• Title/Summary/Keyword: Inhibition rate

Search Result 1,536, Processing Time 0.026 seconds

전처리 공정에 따른 폐 신문지의 효소 가수분해 특성

  • Mun, Nam-Gyu;Lee, Jae-Hwan;Kim, Seong-Bae
    • 한국생물공학회:학술대회논문집
    • /
    • 2000.04a
    • /
    • pp.459-462
    • /
    • 2000
  • The pretreatment of used newspaper for the enzymatic digestion preprocess was performed on a percolation reactor and a batch reactor. The test condition of percolation process was $170^{circ}C$, 60min, 1 mL/min, and 400psi, that of batch was $40^{circ}C$, 3hr. and latm Reaction solutions used in pretreatment process were aqueous ammonia, sulfuric acid, water, and hydrogen-peroxide as an oxidizing agent. As a result, the effect of pretreatment was similar to batch and percolation process, but the yield of enzymatic hydrolysis was higher in batch than percolation. This batch pretreatment enhanced enzymatic hydrolysis rate and increased glucose yield from about 15 to 20%. The inhibition factors influenced the rate of enzymatic hydrolysis was investigated, and the ink contented newspaper was the major factor.

  • PDF

Role of CaO in the Sintering of 12Ce-TZP Ceramics (12Ce-TZP 세라믹스의 소결에서의 CaO의 역할)

  • 박정현;문성환;박한수
    • Journal of the Korean Ceramic Society
    • /
    • v.29 no.4
    • /
    • pp.265-272
    • /
    • 1992
  • Role of CaO in the sintering of 12Ce-TZP ceramics was studied. The addition of small amounts of CaO increase the densification rate of 12Ce-TZP by altering lattice defect structure and the diffusion coefficient of the rate controlling species, namely cerium and zirconium cations. CaO also inhibits grain growth during sintering and allows the sintering process to proceed to theoretical density by maintaining a high diffusion flux of vacancies from the pores to the grain boundaries. The inhibition of grain growth is accomplished by the segregation of solute at the grain boundaries, causing a decrease in the grain boundary mobility. The segregation of calcium was revealed by AES study.

  • PDF

Kinetics for the Growth of Alcaligenes eutrophus and the Biosynthesis of Poly-${\beta}$-hydroxybutyrate (Alcaligenes eutrophus 균주의 성장과 Ploy-${\beta}$-hydroxybutyrate 생합성에 대한 속도론)

  • Lee, Yong-Woo;Yoo, Young-Je
    • Microbiology and Biotechnology Letters
    • /
    • v.19 no.2
    • /
    • pp.186-192
    • /
    • 1991
  • It is very important to have a good kinetic model which considers the effects of both ammonium and glucose for the control and optimization of the poly-${\beta}$-hydroxybutyrate (PHB) fermentation. A kinetic model for the growth of Alcaligenes eutrophus and the biosynthesis of PHB under both ammonium and glucose limitation was proposed. Growth rate of residual biomass was expressed as a function of concentrations of residual biomass, glucose and ammonium having glucose inhibition. PHB production rate was expressed as a function of concentrations of residual biomass, glucose, ammonium and PHB content having ammonium and product inhibitions. Novel approaches were made to estimate the parameters in the model equations which considered two limiting substrates. Model parameters were evaluated by graphical and simplex methods. The proposed kinetic model fitted the data very well.

  • PDF

Evaluation of Sound-induced Affects based on Prefrontal Cortex Asymmetry and Heart Rate Variability (전전두엽의 비대칭성과 심장박동율변동성에 기초한 음향감성 평가)

  • 김원식;이지혜;조문재
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
    • /
    • 2001.11a
    • /
    • pp.138-143
    • /
    • 2001
  • 본 연구에서는 생환공간에서의 음향감성을 평가하기 위하여 긍정감성을 유발하는 음환경으로서 '명상음악'과 부정감성을 유발하는 음환경으로서 '헬리콥터소음'과 '마루가 삐거덕거리는 소음'을 제시하였을 때 행동활성화체계(BAS)와 행동억제체계(BIS)의 민감성이 서로 다른 집단들을 대상으로 전전두엽의(PFC) 비대칭성과 심장박동율변동성(HRV)을 분석하였다. 연구결과, 명상음악을 청취시에는 안정상태에 비하여 좌측전두엽이 더 활성화되고 HRV의 LF/HF는 감소된 반면에 소음환경에서는 우측전두엽이 더 활성화되고 LF/HF는 더 증가하였다.

  • PDF

Effects of Reticuloendothelial Hyperfunction on Preservation of Lung (망내계기능 항진이 폐장보존에 미치는 영향)

  • 박동식
    • Journal of Chest Surgery
    • /
    • v.7 no.2
    • /
    • pp.145-152
    • /
    • 1974
  • The effect of reticuloendothelial hyperfunction on hypothermic preservation of lung was studied in dogs. In order to evaluate the viability after hemodynamic_ load in preserved isolated lung, observations were made on the rate of increase in weight, degree of edema,compliance and surface activity of lung. The results obtained as follows: l. In the group of activating of the reticuloendothelial system by injection of sodium thiosulfate intravenously before pneumonectomy and infusion of naphthionine through the pulmonary artery before hypothermic preservation of isolated lung the limit of preservation was eight hours whereas four hours in non-treated control group. 2.Therefore the method of activating of the reticuloendothelial system before and after pulmonary resection seems effective in preserving for prolonging the period of preservation of lung by means of inhibition of pulmonary edema. 3. Pulmonary surface activity is expected to be valuable as a method in evaluation of the viability of preserved lung along with compliance and rate of increase in weight of lung.

  • PDF

Hydroysis of Rice Straw with Trichoder-ma viride TO4 Cellulase

  • Lee, Mun-Ho;Yong, Pack-Moo
    • Proceedings of the Korean Society for Applied Microbiology Conference
    • /
    • 1978.10a
    • /
    • pp.208.2-208
    • /
    • 1978
  • Rice Straw was delignified by autoclaving with 1% NaOH solution at $121^{\circ}C$ for one hour and was disintegrated by a Wiley mill to 60 mesh. This substrate was saccharified with cellulase produced by Trichoderma viride T04 in solid culture me-dium. The rate and extent of hydrolysis were both increased when high enzyme concentration and low substrate concentration were employed. The original cellulose was treated with 0.19 FPA unit for three hours and followed by the second treatment for the same period with the same concentration of enzyme after washing. By doing this the hydrolysis rate at the second stage could increase four folds of that unwashed. The same experiment with 0.32 FPA unit yielded two folds suggesting an end-product inhibition on the recaction system. The extent of hydrolysis however, could not be in-creased by this process.

  • PDF

Influence of Oxytocin on the Renal Function of the Chicken (닭의 신장기능(腎臟機能)에 미치는 Oxytocin의 영향(影響))

  • Ko, Suk-Tai
    • Journal of Pharmaceutical Investigation
    • /
    • v.1 no.1
    • /
    • pp.34-46
    • /
    • 1971
  • The existence of oxytocin in the pituitary gland of chicken has been ascertained, but its physiological roles are still obscure. In the study the action of oxytocin on renal function of the chicken was investigated during water diuresis, utilizing clearance and the Sperber technique. The results obtained are summarized as follows: Oxytocin, like in many species of mammals, elicited a profound diuretic response in the chicken. Urine flow, excretion of electrolytes, as well as glomerular filteration rate increased, with intravenous infusion of $3{\sim}10\;m{\mu}/kg/min$. Oxtocin, infused into the renal portal circulation via hindleg vein in a dose of $3{\sim}13\;m{\mu}/kg/min$. elicited marked increase in urine flow, glomerular filteration rate and sodium excreted in the urine. The diuretic effect was more pronounced in the infused side. It is suggested that diuretic response to oxytocin in the chicken results from dual action of oxytocin: increase of GFR and inhibition of sodium reabsorption on the renal tubule. The possibility that oxytocin might act through some endogenous substances could be ruled out.

  • PDF

Inhibition of Corticosterone-induced Muscle Protein Synthesis by the Anabolic Steroid Nandrolone Phenylpropionate in Female Rats (아나보릭스테로이드인 Nandrolone Phenylpropionate가 암컷 쥐에서 코티코스테론에 의해 야기된 근육단백질 쇠퇴와 근육단백질 합성율 감소에 미치는 영향)

  • 주종재
    • Journal of Nutrition and Health
    • /
    • v.29 no.8
    • /
    • pp.867-873
    • /
    • 1996
  • This study was undertaken to determine whether the anabolic steroid nandrolone phenylpropionate(NPP) can inhibit the muscle atrophy and reduction in muscle protein synthesis caused by glucocorticoids in female rates. Daily injections of 50mg/kg of corticosterone for eight days induced significant reductions in body weight gain and protein without affecting food intake. The mass, protein and RNA content, ratio of RNA to protein, and fractional rate of protein synthesis, measured in vivo, of gastrocnemius muscle were all significantly reduced by corticosterone treatement. Simultaneous administration of NPP at a dose of 10mg/kg with corticosteorne (50mg/kg) fully inhibited the reductions in the mass, protein and RNA content of gastrocnemius muscle, and body weight gain and protein with no alteration in food intake but the reduction in fractional rate of muscle protein syntheis was only partially prevented. The results indicate that the anabolic steroid nandrolone phenylpropionate is capable of preventing muscle atrophy in female rats treated with excess corticosterion.

  • PDF

The Effect of Nonionic Surfactants on the Solubility and Biodegradation of PAHs in Soil Slurry (PAHs의 용해도와 생분해에 미치는 비이온계 계면활성제의 영향)

  • 박종섭;김인수
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
    • /
    • 1998.11a
    • /
    • pp.174-177
    • /
    • 1998
  • The effects of surfactants affecting polycyclic Aromatic Hydrocarbon(PAHs) solubility and biodegradation in soil slurry were investigated. The critical micelle concentration(CMC) values of surfactants used in this study were 12.7mg/L(Brij 30), 13.4mg/L(Tween 80), 13.6mg/t(Triton X-100). The solubility of PAH increased as the Hydrophile-Lipophile Balance(HLB) value of surfactant decrease. At surfactant biodegradation and toxicity experiement using respirometer, Brij 30 did not show any toxic effect and substrate inhibition upon the level of 1.5g/L. Also, biodegradation of Brij 30 gave no reduction on the phenanthrene biodegradation rate. When the desorption rate of phenanthrene between sand and clay is compared, lower percentage of phenanthrene was desorbed at clay because of the larger surface aera and higher organic content of clay. At the biodegradation experiments of phenanthrene in soil slurry phase, more than 90% of initial phenanthrene adsorbed onto both sand and clay were biodegraded by phenanthrene- acclimated cultures.

  • PDF

$\alpha$-Glucosidase Inhibition by Culture Broth of Streptomyces sp. NS15 (Streptomyces sp. NS15 배양액에 의한 $\alpha$-Glucosidase 저해)

  • 백남수;김영만
    • The Korean Journal of Food And Nutrition
    • /
    • v.11 no.6
    • /
    • pp.640-646
    • /
    • 1998
  • For the production of nonprotein $\alpha$-glucosidase inhibitor from the Streptomyces sp. NS15 strain, effects of initial optimum pH, nitrogen sources, carbon sources, cationic metal ions, agitation speed and aeration rate were investigated. Initial optimum pH of medium was 7.0. The most effective nitrogen and carbon sources were soybean meal 2.0%(w/v) and glucose 1.6%(w/v), respectively. The cationic metal ins had no stimulating effect on inhibitory activity of $\alpha$-glucosidase except Fe2+. Agitation speed and aeration rate were effective at 400rpm and 1vvm, respectively. In the jar-fermenter cultivation for 4 days under optimal culture conditions, the culture broth showed the inhibitory acitivity of 3,200units/ml, which is 25 times higher than that of basic medium (CYM) for porcine intestinal $\alpha$-glucosidase. The inhibitory activity of $\alpha$-glucosidase reached about 3,200units/ml after 4 days of cultivation and decreased gradually for a further two days.

  • PDF