• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2535-2537
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• 2016

Background: Most of the cervical cancer patients, including those with cervical adenocarcinomas, come at advanced stage in the developing world so its mortality is high. Radiotherapy is one of the treatment modality for advanced stage cervical adenocarcinomas, but its efficacy depends on several prognostic factors such as the stage, histopathology, presence of organ dysfunction and expression of cellular biology markers mainly involve in cell proliferation such as the epidermal growth factor receptor (EGFR). Some research indicates that activation of EGFR in malignancy (including cervical cancer) correlates with aggressive behavior, a poor prognosis and decreasing sensitivity of radiotherapy. However, the combination between targeted therapies and radiotherapy are innovative approaches which may provide a good result. This study aimed to assess any correlation between expression of EGFR and response to radiotherapy in cervical adenocarcinoma cases. Materials and Methods: A total of 32 women were registered in a retrospective study period January 2007 and May 2014. Paraffin blocks from these patients were processed by classical histological techniques and for immunohistochemical staining of EGFR, scoring being accomplished according to the immunoreactive scoring (IRS) of Remmele and Stegner. Results: Among the studied molecular factors, there was significant correlation expression of EGFR with poor response to radiotherapy (p=0.0001). Conclusions: The result of this study showed a significant correlation between expression of EGFR and sensitivity of radiation in cervical adenocarcinoma cases. Further research is necessary to obtain information about new therapeutic management.

• Journal of Korean Academy of Nursing
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• v.43 no.5
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• pp.681-689
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• 2013

Purpose: The purpose of this study was to examine effects of the Permission, Limited Information, Specific Suggestions, Intensive Therapy (PLISSIT) model sexual health enhancement program on, and development in, sexual function, sexual distress, marital intimacy, and subjective happiness of women with gynecologic cancer and their husbands. Methods: The comprehensive program (4 session, 90 minutes per session) was developed based on the PLISSIT model. Participants were 43 couples, 21 assigned to the experimental group who attended the 4-week program, and 22 to the control group. Sexual function, sexual distress, marital intimacy, subjective happiness of the women, marital intimacy, subjective happiness of husbands were determined by a questionnaire that was completed by the participants before and after the program. The control group received the intervention post experiment. Chi-square test, t-test, Fisher's exact test were used to test the effectiveness of the program. Results: Post intervention results showed significant differences between the groups for sexual function, sexual distress, and marital intimacy in the women and for subjective happiness in the husbands. Conclusion: Results indicate that the sexual health enhancement program is effective in improving sexual function, lowering sexual distress, increasing marital intimacy, and subjective happiness in women with gynecologic cancer and their husbands.

• Journal of Korean Academy of Nursing
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• v.41 no.4
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• pp.471-480
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• 2011

Purpose: The purpose of this study was to evaluate the effectiveness of the Permission, Limited Information, Specific Suggestions, Intensive Therapy (PLISSIT) model sexual program on female sexual function for women with gynecologic cancer. Methods: The integrative 6-hr (two hours per session) program reflecting physical and psychosocial aspects of women's sexuality was developed based on Annon's PLISSIT model. Participants were 61 women with cervical, ovarian, or endometrial cancer. Of them, 29 were assigned to the experimental group and 32 to the control group. The women completed the Female Sexual Function Index (FSFI) including sexual desire, arousal, lubrication, orgasm, satisfaction, and pain. Independent t-test and repeated measured ANOVA were used to test the effectiveness of the program. Results: Significant group differences were found on FSFI sub-domain scores including sexual desire, arousal, lubrication, orgasm, and satisfaction but not pain. Significant time differences were found on all domains except for pain in the experimental group repeated measured ANOVA. Conclusion: The results indicate that the three-week PLISSIT model sexual program is effective in increasing sexual function for women with gynecologic cancer. Nurses may contribute to improving women's sexual function by utilizing the program. Strategies to relieve sexual pain need to be considered for greater effectiveness of the program.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.1
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• pp.255-262
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• 2011

The advancement of information and communication technology has caused a few dysfunction such as hacking. To keep an organization from a harmful hacking, demands for cryptographic modules have been increased. However, the evaluation criteria of cryptographic modules in Korea have been less firmly established. It is difficult for the consumers of cryptographic module to choose an appropriate cryptographic module, and to establish interoperability between applications and cryptographic modules. This study analyzes evaluation criteria, evaluation processes and evaluation policy of CMVP(Cryptographic Module Verification Program) in the advanced countries. The paper suggests a policy for Korea CMVP, in resulting a provision of foundations for international standard and cooperations for international cryptographic policies and systems.

• Advances in robotics research
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• v.1 no.2
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• pp.155-169
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• 2014

Study results in the last decades show that amount and quality of physical exercises, then the active participation, and now the cognitive involvement of patient in rehabilitation training are known of crux to enhance recovery outcome of motor dysfunction patients after stroke. Rehabilitation robots mainly have been developing along this direction to satisfy requirements of recovery therapy, or focusing on one or more of the above three points. Therefore, neuro-machine interaction based active rehabilitation robot has been proposed for assisting paralyzed limb performing designed tasks, which utilizes motor related EEG, UCSDI (Ultrasound Current Source Density Imaging), EMG for rehabilitation robot control and feeds back the multi-sensory interaction information such as visual, auditory, force, haptic sensation to the patient simultaneously. This neuro-controlled and perceptual rehabilitation robot will bring great benefits to post-stroke patients. In order to develop such kind of robot, some key technologies such as noninvasive precise detection of neural signal and realistic sensation feedback need to be solved. There are still some grand challenges in solving the fundamental questions to develop and optimize such kind of neuro-machine interaction based active rehabilitation robot.

• Journal of Applied Biological Chemistry
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• v.54 no.2
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• pp.101-107
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• 2011

Aging in females is associated with a reduced metabolic function, increased incidence of neurodegenerative diseases, and cognitive dysfunction, as a result of loss in gonadal function. The change can alter the states of phosphorylation on the proteins, which cause dramatic changes in the cellular location or activity of the proteins. In this study, the differential phosphorylation of the proteins responsible for the functions related to cognition was studied using the ovariectomized adult rats. Phosphoproteomic analysis using the cerebral and hippocampal tissues could identify 51 differentially phosphorylated proteins including 12 proteins for energy metabolism, 8 cytoskeletal proteins, 6 signaling proteins, and other functional proteins in the ovariectomized rats. Further, anti-oxidative enzymes, superoxide dismutase and peroxiredoxin-2, which are known to be inactivated by phosphorylation, were found to be differentially phosphorylated in the cerebellum and hippocampus of the ovariectomized rats, respectively. Many of the deactivated proteins by differential phosphorylation identified in this study were overlapped to those of Alzheimer's disease cases. These results will provide information for neurodegenerative learning and memory impairments in women as brought about by menopause.

• Journal of Satellite, Information and Communications
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• v.12 no.1
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• pp.22-27
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• 2017

In this paper, A heightened interest in the latest drone, yet steady increase in the field to exploit them. The next market is expected to be vastly improved, and use drone also increasingly will be strengthened. But also not a few side effects of him. In order to use safer and more commonly a drone safety and privacy protection, and there are many issues that need to be considered. Violating privacy laws, such as relations caused by the drone flight and review this study ways to resolve the breach. The flight due to a draw at peace with human life and behavior and enjoy it, but this problem created by new outbreak.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.12
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• pp.5047-5056
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• 2016

Colorectal cancer (CRC) is a major worldwide health problem owing to its high prevalence and mortality rates. Carcinogenesis in the colon is a multistage and multifactorial process. An imbalance between free radical exposure and anti-oxidant defense systems may leads to oxidative stress and attack of macromolecules which can alter signal transduction pathways and gene expression. Consequently, oxidative damage can lead to cellular dysfunction and contribute to pathophysiological processes in a variety of diseases including CRC. One factor tightly associated with CRC is chronic inflammation, which can be present from the earliest stage of tumor onset. Unpolished rice is an attractive chemoprevention in CRC due to their anti-oxidant and anti-inflammatory activities. The aim of this paper is to review evidence linking oxidative stress and inflammation to CRC and to provide essential background information for understanding future research on oxidative stress and inflammation on CRC. Mechanisms of action of unpolished rice in CRC carcinogenesis are also discussed.

• Korean Journal of Adult Nursing
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• v.29 no.3
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• pp.225-234
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• 2017

Purpose: The aim of this study was to evaluate the effect of sexual health program for men with rectal cancer resection based on sexual function, self-esteem, depression, and marital intimacy. Methods: Using a quasi-experiment design, the intervention group (n=32) participated in the sexual health program based on PLISSIT (Permission, Limited Information, Specific Suggestions, Intensive Therapy) model. They received the program three times between August 2014 and March 2015. The comparison group (n=30) received a general educational program for rectal cancer. Four survey questionnaires such as International Index of Erectile Function (IIEF), Self-Esteem Scale, Center for Epidemiologic Studies Depressing Scale (CES-D), Marital Intimacy were used to measure the four key variables. Results: After the sexual health program, the intervention group showed statistically positive effect for the sexual function (F=4.14, p=.046), self-esteem (F=16.71, p<.001), depression (F=12.56, p=.001), and marital intimacy (F=12.45, p=.001) than the comparison group. Conclusion: Sexual health program should be consistently provided for men with rectal cancer resection since the intervention group reported better self-esteem, less depression, more intimacy and better sexual functioning.

• The Journal of the Korea Contents Association
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• v.5 no.6
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• pp.360-367
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• 2005

Corporation's computerization developed by diffusion of internet, and dysfunction of Information is increasing greatly with virus, computing network infringement. Therefore, the today, corporation security is more and more emphasized. Security solution by that importance of security rises so is developing together Security solution is developing to ESM system in existing single system and important thing is function of each security solution and optimizing design of policy. Existent security policy taking a serious view security from external invasion but security of interior the importance rise the today. Accordingly, must construct ESM system of new structure for this. This paper proposes and embodied integration security administration system that solidify interior security utilizing IDS. Experiment external IP and ID access and analyzed the result.