• Nutrition Research and Practice
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• 제12권1호
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• pp.61-68
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• 2018

BACKGROUND/OBJECTIVES: This study aimed to test the association between APOA5 3'-UTR variants (rs662799) and cardiometabolic traits in Koreans. SUBJECTS/METHODS: For this study, epidemiological data, Apolipoprotein A5 (APOA5) genotype information, and lymphoblastoid cell line (LCL) biospecimens from a subset of the Ansung-Ansan cohort within the Korean Genome and Epidemiology study (KoGES-ASAS; n = 7,704) as well as epidemiological data along with genomic DNA biospecimens of participants from a subset of the Korea National Health and Nutrition Examination Survey (KNHANES 2011-12; n = 2,235) were obtained. APOA5 mRNA expression was also measured. RESULTS: APOA5 rs662799 genotype distributions in both the KoGES-ASAS and KNHANES groups were 50.6% for TT, 41.3% for TC, and 8.1% for CC, which are similar to those in previous reports. In both groups, minor C allele carriers, particularly subjects with CC homozygosity, had lower high-density lipoprotein (HDL) cholesterol and higher triglyceride levels than TT homozygotes. Linear regression analysis showed that the minor C allele significantly contributed to reduction of circulating HDL cholesterol levels [${\beta}=-2.048$, P < 0.001; ${\beta}=-2.199$, P < 0.001] as well as elevation of circulating triglyceride levels [${\beta}=0.053$, P < 0.001; ${\beta}=0.066$, P < 0.001] in both the KoGES-ASAS and KNHANES groups. In addition, higher expression levels of APOA5 in LCLs of 64 healthy individuals were negatively associated with body mass index (r = -0.277, P = 0.027) and circulating triglyceride level (r = -0.340, P = 0.006) but not significantly correlated with circulating HDL cholesterol level. On the other hand, we observed no significant difference in the mRNA level of APOA5 according to APOA5 rs662799 polymorphisms. CONCLUSIONS: The C allele of APOA5 rs662799 was found to be significantly associated with cardiometabolic traits in a large Korean population from the KoGES-ASAS and KNHANES. The effect of this genotype may be associated with post-transcriptional regulation, which deserves further experimental confirmation.

• Nutrition Research and Practice
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• 제12권1호
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• pp.69-77
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• 2018

BACKGROUND/OBJECTIVES: Metabolic risk factors should be managed effectively in patients with type 2 diabetes mellitus (T2DM) to prevent or delay diabetic complications. This study aimed to compare the self-management levels of diet and metabolic risk factors in patients with T2DM, according to the duration of illness, and to examine the trends in self-management levels during the recent decades. SUBJECTS/METHODS: Data were collected from the Korea National Health and Nutrition Examination Surveys (KNHANES, 1998-2014). In our analysis, 4,148 patients with T2DM, aged ${\geq}30years$, were categorized according to the duration of their illness (< 5 years, 5-9 years, and ${\geq}10years$). Demographic and lifestyle information was assessed through self-administered questionnaires, and biomarker levels (e.g., fasting glucose level, blood pressure, or lipid level) were obtained from a health examination. Dietary intake was assessed by a 24-recall, and adherence level to dietary guidelines (meal patterns and intake levels of calories, carbohydrates, vegetable/seaweed, sodium, and alcohol) were assessed. Multivariable generalized linear regression and unconditional logistic regression models were used to compare the prevalence rates of hyperglycemia, dyslipidemia, and hypertension according to the duration of patients' illness, accounting for the complex survey design of the KNHANES. RESULTS: In the multivariable adjusted models, patients with a longer duration (${\geq}10years$) of T2DM had a higher prevalence of hyperglycemia than those with a shorter duration of T2DM (< 5 years) (odds ratio 2.20, 95% confidence interval 1.61-3.01, P for trend < 0.001). We did not observe any associations of disease duration with the prevalence of hypertension and dyslipidemia. In addition, the adherence levels to dietary recommendations did not significantly differ according to disease duration, except adherence to moderate alcohol consumption. There were significant decreasing trends in the prevalence of hyperglycemia in patients with a duration of illness ${\geq}10years$ (P for trend = 0.004). CONCLUSION: Although the proportion of patients with adequate control of glucose levels has improved in recent decades, poorer self-management has been found in those with a longer disease duration. These findings suggest the need for well-planned and individualized patient education programs to improve self-management levels and quality of life by preventing or delaying diabetic complications.

• Journal of Acupuncture Research
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• 제32권3호
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• pp.95-105
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• 2015

Objectives : The purpose of this study is to review the characteristics of patients who visited the emergency room of a Korean medical hospital with musculoskeletal disorders during the last 5 years and to provide a potential basis for future studies and emergency medical practice. Methods : Patient visit records between May 1st, 2010 and February 28th, 2015 were reviewed and patients with musculoskeletal disorders were included in a retrospective analysis. Results : A total of 5,218 patient visit records were initially reviewed and 1,485 patients (28.46 %) were included in the analysis. S code group was the most frequently diagnosed coding group of Korean Standard Classification of Diseases. The male to female ratio was 1.05:1 and patients in their thirties represented the highest age group. When classified by time of visit, the distribution of patients was similar from 10:00 to 22:59. The most frequently visited day and month were Sunday and September. 879 patients (59.19 %) visited the emergency room within 24 hours from onset of symptoms. The most common symptom site was the low back (45.59 %), followed by ankle (13.94 %) and neck (13.80 %). The most frequently used treatment method was acupuncture (92.32 %), followed by infrared (45.45 %), TENS (30.03 %) and herbal medication (29.02 %). The follow-up and admission rates were 30.24 % and 13.00 % respectively. 343 patients (23.10 %) received Western medical treatment within a day before visiting the emergency room of the Korean medical hospital. Conclusions : This analysis provides the latest information on the characteristics of patients who visited the emergency room of a Korean medical hospital with musculoskeletal disorders. The results can provide the basis for further studies and for other attempts to improve the clinical setting of the emergency room.

• 한국수자원학회논문집
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• 제37권11호
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• pp.897-913
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• 2004

지금까지 국내에서는 도시하수, 공장폐수 등의 점오염원에 국한하여 수질관리를 시행하여 부분적으로 밖에 효과를 얻지 못하였다. 따라서 오염원에 대한 최적관리를 위해서는 유역의 토지특성 및 토양 형태에 따른 비점오염원에 대한 관리가 매우 중요하다. 본 연구에서는 유역의 특성별로 발생하는 오염원을 산정하기 위해 분포형 모형을 적용하였으며, 상세한 유역특성 자료를 구축하기 위해 GIS 기법을 응용하였다. 본 연구에서는 분포형 수질관리모형으로 연속 강우 사상에 대해 유역에서 발생하는 유출량 및 첨두유량, 유사량, 비점오염 부하량 등을 산정할 수 있는 AnnAGNPS 모형을 적용하였고, 모형내의 부모듈을 이용하여 입력자료를 생성 및 가공하여 적용하였다. 대상유역은 팔당호 유역권에 포함되는 복하천 유역을 선정하였으며, 1999년과 2000년 호우기의 각각 2개의 강우 사상을 적용하였다. 우선 강우시 유역에서 발생하는 유출량을 모의하고, 이를 복하교 지점의 실측유량자료와 비교, 보정하여 모형의 입력 매개변수를 조정하였으며, 이후 토사발생량과 오염부하량을 모의하였다 토사발생량의 경우는 실측값이 미비하여 비교분석은 못하였으나, 오염부하량의 경우 환경부에서 측정한 수질농도 자료를 이용하여 비교, 분석값을 제시하였다.

• 정보처리학회논문지D
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• 제13D권2호
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• pp.271-278
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• 2006

본 논문은 CE(Consumer Electronics) 제품을 개발하는 기업에서 소프트웨어 재사용의 향상을 위하여 기업 내에서 추진한 여러 사례들을 기반으로 소프트웨어 재사용에 대한 기반을 구축하고, 이를 개발 조직에 적용하면서 발생한 문제점의 도출과 개선점의 반영에 대해 논한다. 기업내에서의 재사용 기반을 구축하기 위해서는 기술적, 관리적, 개발환경의 측면이 모두 고려된 종합적인 접근 방법이 필요하다. 본 논문에서는 기술적 측면에서 개발 방법론을, 관리적 측면에서 재사용 메트릭을, 그리고 개발환경의 측면에서 재사용 저장소를 개발하고 운영한 사례를 논하며, 각각을 적용하면서 발생한 문제점을 분석하여 기업에서 보다 효과적인 재사용 기반을 구축하는 개선사례를 제시한다. 본 논문에서 다루는 재사용 활동의 대상은 개발대상 측면에서 내장 소프트웨어라는 특성, 조직적 측면에서 다앙한 제품을 다루는 수십 개의 각기 다른 개발영역과 조직구조를 가진 대규모 조직이라는 특성, 그리고 제품 개발 주기가 매우 짧으며 동일 제품에 대한 파생 제품이 동시에 다량으로 개발된다는 개발 환경의 특성에 기반하고 있다. 본 논문은 상기 분야에 대한 소프트웨어 재사용 현황에 대한 보고서로, 또한 이로부터 기업 내 재사용 기반을 개선하는 사례와 그 방안을 제시한다는 측면에서의 활용도가 있겠다.

• 한국콘텐츠학회논문지
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• 제11권3호
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• pp.220-229
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• 2011

본 연구는 연극배우 157명을 대상으로 연습 및 공연상황에서 심리요인의 중요도, 심리문제의 경험과 해결 방법, 공연에서의 공헌도와 조절 능력, 심리상담에 관한 요구 등의 심리적 지원에 대한 전반적 인식과 발전 방안에 대해 분석하였다. 이를 위해 전문가회의를 통해 개발된 질문지로 양적, 질적분석을 실시한 결과, 연극배우들은 심리상담 및 심리기술과 같은 심리적 지원의 역할을 매우 긍정적으로 인식하고 있는 것으로 나타났다. 연극배우들은 연습과 공연상황에서 심리요인이 매우 중요한 역할을 한다고 믿고 있었지만, 심리적 지원에 관한 교육참여와 정보제공이 매우 낮게 나타났다. 또한 배우들의 자신감, 집중력, 성취의지, 동기, 긍정적 태도와 생각, 공연에 대한 목표, 감정조절, 심상능력, 각성조절 능력 등의 심리요인은 공연에서 높은 공헌도가 있음에도 불구하고, 실제 심리적 조절능력이 떨어지는 것으로 나타났다. 연극배우들은 심리적 지원에 대한 참여에 적극적인 태도를 갖고 있으며, 체계적인 심리상담과 심리기술에 대한 연습을 원하고 있는 것으로 밝혀졌다. 이러한 연구 결과는 연극배우에 맞는 심리적 지원 체계 마련, 심리적 지원 프로그램 개발, 실제적 현장 교육 실시 등의 연극학계의 현장 지원 노력의 지침으로 활용될 수 있을 것이다.

• 한국지역사회생활과학회지
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• 제17권1호
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• pp.141-154
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• 2006

The purpose of this study is to provide the information of the aged olds for which basic data are almost no available. The subjects were divided on the base of age 75. The elderly under 75 were named 'the young olds' and over 75 were 'the aged olds'. The aim of this research is to promote health and to improve nutrition, and the survey was made for health promotion behaviors, habits against health risk, dietary management status and diet intake. And it was conducted by 24 hr-recall method and analyzed by nutrients intake. 242 subjects were collected in 12 cities or counties in Gyeonggi Province and 20 elderly people (10 male and 10 female) were selected out of 1 village in each district. Questionnaire about health behavior and dietary management was carried out by interview method through regional home extension workers. Statistical analyses were made by SAS (version 8.1) and Chi-square tests and General Linear Models were used. Out of the subjects the aged olds over 75 was 31.9%, elementary school educated (93.5%), with spouse (40.3%), with adult children(28.6%), monthly living cost of 500-1,000 thousand won(40.3%). Mean age was 78.82 years compared with 69.75 years of the young olds. 46.8% of the aged olds used monthly pocket money over 1000 won and it was lower than 63.3% of the young olds. Only half of the aged olds had regular exercise of walking (77.8%) or with athletic equipment (17.8%). However, the young olds did more frequent walking (82.1 %) and less exercise with athletic equipment (4.8 %), which was significantly different. Kinds of disease were different with the young or the aged olds, as more proportion of cardiovascular disease(37.9%) for the young olds and joint lumbago neuralgia(41.6%) for the aged olds. Dietary management was good (3 meals per day: 93.4%, fixed mealtime: 72.4%, and regular amount: 79.9%). But there was significant difference in side dish varieties and kinds of snacks; for the aged olds only 8% had over 5 sorts (compared with 18.8% of the young olds) and the kinds of snacks were cookie, candy, juice, carbonated beverage for the aged olds (compared with noodle, milk, soybean-milk for young olds). The ratio of nutrients intake (energy, riboflavin and niacin) with RDA was significantly higher for the aged olds than that of the young olds. The surveyed subjects had no difficulties in Activities of Daily Living (ADL), but some of the aged olds had difficulties in Instrumental Activities of Daily Living (IADL) like housekeeping, using transportation, going shopping and making phone calls. These results suggest that low quality of life is linked with low economic status of the rural elderly and congregate meal at village hall would be required because of the lack of side dishes variety for the aged olds. And nutrition education program about good snacks and exercise practice would be needed for the aged olds. By operating nutrition education program the aged olds would enjoy better quality life maintaining or ameliorating IADL abilities.

• 한국치위생학회지
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• 제11권5호
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• pp.671-683
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• 2011

Objectives : The purpose of this study was to examine the oral health knowledge and actual oral health care of the selected subjects, their decision making about prosthetic treatment, the state and characteristics of their prosthetic treatment and their satisfaction with prosthetic treatment in an attempt to provide some information on the improvement of the quality of life related to oral health and the promotion of oral health. Methods : The subjects in this study were 250 people who received education in two different lifelong education institutions in the city of Busan. After a survey was conducted from May 23 to June 15, 2011, the answer sheets from 217 respondents were analyzed. Results : 1. As for the general characteristics of the respondents, the men(52.1%) outnumbered the women. Those who were in their 60 and up(47.5%) made up the largest age group, and the married people(65.4%) outnumbered the unmarried ones. By occupation, the company employees(20.3%) made up the biggest group. By education, the greatest group was high-school graduates(36.1%). By monthly mean income, the biggest group gained an income of 2.01 million won or more(36.9%). As to medical security, community-based insurance was most prevailing (36.9%). In terms of health promotion, the largest group worked out to stay fit(52.4%). 2. Regarding oral health knowledge, they had a good knowledge about the cause of dental caries(56.7%), but they weren't well aware of the right time for regular dental checkup(47.9%). In relation to oral health care, regular scaling wasn't prevailing(16.9%). 3. Regarding connections between the general characteristics and satisfaction with prosthesis, the less-educated respondents expressed significantly more dissatisfaction(p=0.015). By monthly mean income, those who had a smaller income were dissatisfied in general(p=0.028). Conclusions : The findings of the study illustrated that it's required to spread awareness of the importance of oral health among people in general, and that differentiated incremental oral health care should be provided for different age groups. In order to raise the satisfaction of patients with prosthesis, how to relieve their pain and anxiety and how to adjust prosthetic treatment cost properly should carefully be considered. In addition, the government should take measures to offer assistance for the low-income classes in preparation for an increase in the elderly population.

• 시큐리티연구
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• 제39호
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• pp.387-411
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• 2014

학교폭력은 더 이상 피해자와 가해자 당사자만의 문제가 아니며, 학교, 가정, 그리고 국가에도 그 책임이 있는 사회적 문제로 인식되고 있다. 학교폭력 문제를 해결하기 위해서 학교 내 외에서 발생하는 범죄와 안전을 위해하는 요소는 매우 다양하지만 이 중 학교에서 발생하는 학생간의 폭력을 중심으로 학교폭력의 발생 실태를 살펴보고자 한다. 또한 안전한 학교를 조성하기 위하여 경찰이 학교라는 범위 내에서 행하고 있는 활동의 실태를 살펴보고 그에 따른 문제점은 무엇인지를 확인한다. 더 나아가 학교폭력에 효과적으로 대응하기 위한 방안으로서 민간경비를 적절히 활용할 수 있는 방안에 대해서 논해보고자 한다. 현대 사회에서 치안서비스에 대한 국민들의 기대수준은 시간이 흐를수록 상승하고 있으나 경찰의 한정된 자원만으로는 감당하기에 부족한 현상이 발생하고 있다. 지금까지 국가가 독점했던 경찰활동은 다양한 치안활동의 주체들과 협력하는 시스템으로 변해가고 있으며, 지역사회는 경찰이 감시하고 법을 집행해야 할 대상 또는 공간이 아니라 효율적인 경찰활동을 위한 협력자로 인식하고 있다. 경찰력의 한계 등의 측면에서 바라볼 때 민간경비의 활용은 매우 효과적인 방안이 될 수 있다. 학교폭력 예방을 위한 민간경비의 활용을 위해서는 민간경비원에 대한 임무 및 법적 권한을 부여하고 학교폭력예방을 위한 업무와 함께 교내의 위험한 사각지대 순찰활동 등 방범활동을 위하여 학교와 구체적인 정보를 공유하여야 한다. 또한 물리적 기계적 경비 시스템을 도입하여 학교폭력 예방에 노력을 기울여야 할 것이다.

• 한국임상수의학회지
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• 제26권2호
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• pp.130-133
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• 2009

검사키트의 신속성과 간편성이 보편화되면서 진단목적으로 키트를 사용하는 빈도가 증가하고 있다. 그러나 대부분의 검사키트는 민감도와 특이도가 100% 완벽하지 못하기 때문에 진단검사의 특성과 이러한 특성에 영향을 미치는 요인을 이해하지 못할 경우 검사결과를 해석하는데 오류를 범하게 된다. 임상의는 검사결과 양성 혹은 음성일 때 환자가 실제로 질병에 감염되어 있을 확률이 어느 정도인지에 관심을 두기 때문에 본 연구에서는 예측도를 이용하여 유병율에 따른 결과 해석방법을 개 심장사상충 진단키트를 예로 들어 설명하였다. 문헌고찰 결과 심장사상충 진단용 키트검사의 평균 민감도와 특이도는 DiroChek 78.1-95.2%, SNAP 66.3-98.1%, Solo Step 69.5-97.5%를 보였다. 혈액학적 검사법(Modified Knott's, direct smear, capillary tube)의 민감도와 특이도는 각각 38.4-81.8%, 96.9-100%의 범위를 보여 검사법에 따라 상당한 차이를 보였다. 또한 국내 개 심장상충의 자충과 항원 유병율은 지역별로 차이가 있으며 키트검사의 예측도는 유병율에 매우 민감하다는 점을 고려하면 개 심장사상충에 대한 검사결과에 근거하여 감염확률을 추정할 때 유병율이 상이한 임상환경에서는 양성 혹은 음성결과에 대하여 신중하게 해석할 필요가 있다.