• Journal of the Korea Society for Simulation
• /
• v.23 no.4
• /
• pp.181-188
• /
• 2014

Heterogeneous physical systems and computational devices are incorporated on a large-scale in a CPS (cyber-physical system) environment. Simulations can be useful for the reliable behaviors of CPSs. Time synchronization is one of major technical issues for the simulations. In the CPS, distributed systems control themselves by interacting with each other during runtime. When some simulation models have high complexity, wrong control commands as well as incorrect data can be exchanged due to the time error. We propose a time synchronization algorithm for the hybrid model that has characteristics of both continuous time systems and discrete event systems. In addition, we develop a CPS simulator based on our algorithm. For the verification of the algorithm and the execution of the simulator, we develop an example hybrid model and simulate considering user controls as well as interactions among the distributed systems.

• Journal of Ginseng Research
• /
• v.40 no.2
• /
• pp.151-159
• /
• 2016

Background: Ginsenoside-Rg3, the pharmacologically active component of red ginseng, has been found to inhibit tumor growth, invasion, metastasis, and angiogenesis in various cancer models. Previously, we found that 20(R)-ginsenoside-Rg3 (Rg3) could inhibit angiogenesis. Since microRNAs (miRNAs) have been shown to affect many biological processes, they might play an important role in ginsenoside-mediated angiomodulation. Methods: In this study, we examined the underlying mechanisms of Rg3-induced angiosuppression through modulating the miRNA expression. In the miRNA-expression profiling analysis, six miRNAs and three miRNAs were found to be up- or down-regulated in vascular-endothelial-growth-factor-induced human-umbilical-vein endothelial cells (HUVECs) after Rg3 treatment, respectively. Results: A computational prediction suggested that mature hsa-miR-520h (miR-520h) targets ephrin receptor (Eph) B2 and EphB4, and hence, affecting angiogenesis. The up-regulation of miR-520h after Rg3 treatment was validated by quantitative real-time polymerase chain reaction, while the protein expressions of EphB2 and EphB4 were found to decrease, respectively. The mimics and inhibitors of miR- 520h were transfected into HUVECs and injected into zebra-fish embryos. The results showed that overexpression of miR-520h could significantly suppress the EphB2 and EphB4 protein expression, proliferation, and tubulogenesis of HUVECs, and the subintestinal-vessel formation of the zebra fish. Conclusion: These results might provide further information on the mechanism of Rg3-induced angiosuppression and the involvement of miRNAs in angiogenesis.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.15 no.26
• /
• pp.111-117
• /
• 1992

In the stock marketing. investor needs speedy and accurate decision making for the investment. A stock exchange index provides the important index of the early of 1993 in Korea using Fuzzy Delphi Method(F. D. M) which is widely used to a mid and long range forecasting in decision making problem. In the Fuzzy Delphi method, considerably qualified experts an first requested to give their opinion seperately and without intercommunication. The forecasting data of experts consist of Triangular Fuzzy Number (T.F.N) which represents the pessimistic, moderate, and optimistic forecast of a stock exchange index. A statistical analysis and dissemblance index are then made of these subject data. These new information are then transmitted to the experts once again, and the process of reestimation is continued until the process converges to a reasonable stable forecast of stock exchange index. The goal of this research is to forecast the stock exchange index using F.D.M. in which subjective data of experts are transformed into quasi -objective data index by some statistical analysis and fuzzy operations. (a) A long range forecasting problem must be considered as an uncertain but not random problem. The direct use of fuzzy numbers and fuzzy methods seems to be more compatible and well suited. (b) The experts use their individual competency and subjectivity and this is the very reason why we propose the use of fuzzy concepts. (c) If you ask an expert the following question: Consider the forecasting of the price index of stocks in the near future. This experts wi11 certainly be more comfortable giving an answer to this question using three types of values: the maximum value, the proper value, and the minimum value rather than an answer in terms of the probability.

• Journal of Ginseng Research
• /
• v.42 no.1
• /
• pp.57-67
• /
• 2018

Background: Ginseng contains many small metabolites such as amino acids, fatty acids, carbohydrates, and ginsenosides. However, little is known about the relationships between microorganisms and metabolites during the entire ginseng fermentation process. We investigated metabolic changes during ginseng fermentation according to the inoculation of food-compatible microorganisms. Methods: Gas chromatography mass spectrometry (GC-MS) datasets coupled with the multivariate statistical method for the purpose of latent-information extraction and sample classification were used for the evaluation of ginseng fermentation. Four different starter cultures (Saccharomyces bayanus, Bacillus subtilis, Lactobacillus plantarum, and Leuconostoc mesenteroide) were used for the ginseng extract fermentation. Results: The principal component analysis score plot and heat map showed a clear separation between ginseng extracts fermented with S. bayanus and other strains. The highest levels of fructose, maltose, and galactose in the ginseng extracts were found in ginseng extracts fermented with B. subtilis. The levels of succinic acid and malic acid in the ginseng extract fermented with S. bayanus as well as the levels of lactic acid, malonic acid, and hydroxypruvic acid in the ginseng extract fermented with lactic acid bacteria (L. plantarum and L. mesenteroide) were the highest. In the results of taste features analysis using an electronic tongue, the ginseng extracts fermented with lactic acid bacteria were significantly distinguished from other groups by a high index of sour taste probably due to high lactic acid contents. Conclusion: These results suggest that a metabolomics approach based on GC-MS can be a useful tool to understand ginseng fermentation and evaluate the fermentative characteristics of starter cultures.

• Journal of Convergence for Information Technology
• /
• v.7 no.3
• /
• pp.127-137
• /
• 2017

Sally Potter's movie, Orlando is a bold re-make of Virginia Woolf's classic novel, Orlando: A Biography, in which an English nobleman survives 400 years - as a man and then a woman. This paper focuses on a study of the film of Orlando in light of the feministic view. In Woolf's gender-bending, time-traveling novel, Orlando, Woolf probes the ideology of patriarchal society through an androgynous persona. Sally Potter's adroit revision of Woolf's novel not only duplicates Woolf's Orlando but it also catches Woolf's feminism by using cinematic expertise. The film is incredibly true to Woolf's spirit. The most explicit changes were structural so the storyline was simplified. Thus Orlando gives us a license to travel freely from a man to a woman. In short, Orlando is not about feminism but the unity and harmony of male and female.

• Journal of Convergence for Information Technology
• /
• v.7 no.3
• /
• pp.1-12
• /
• 2017

The purpose of this study is to contribute to research on dementia and policy making by reviewing research trends of dementia for 15 years and it was collected from 12,588 dementia - related research data for 15 years at Google 's scalar site. The results of this study confirm that the research on dementia, one of the most common geriatric diseases, is continuously increasing. Second, research on dementia is increasing due to social influences such as government support. Third, we suggested that dementia is changing from a viewpoint of diseases to be managed at the facility and treatment of severe dementia patients to a paradigm from the viewpoint of management of mild patients and community participation. Fourth, dementia seems to be shifting from a serious and negative awareness to a social atmosphere that is accepted as a slow but manageable disease. This is changing to a dementia-friendly social environment, which is making a very positive environmental change. This study contributes to the field research by presenting the trend of domestic research on dementia.

• Journal of Convergence for Information Technology
• /
• v.7 no.3
• /
• pp.37-46
• /
• 2017

The purpose of this study was to determine halitosis perception status of firefighters and identify the factors related to halitosis; for this purpose, a survey was conducted in 241 firefighters in Daejeon, obtaining the following results: First. The higher level of smoking and alcohol intake, the more likely to perceive halitosis; all of those with a general disease perceived halitosis; and the more stress, the more likely to perceive halitosis. Second, The respondents who brushed their teeth three times a day, who spent 1~2 minutes in brushing their teeth, who failed to wash their tongue, and who had never received oral health education were most likely to perceive halitosis. And third. such factors as age, the amount of tongue coating, and dry mouth affected halitosis perception status. Firefighters' halitosis perception is related to several factors. For this reason, emphasis is placed on the need to develop a program for helping firefighters prevent halitosis and remove oral symptoms and to give education for good oral health management.

• Journal of Convergence for Information Technology
• /
• v.7 no.3
• /
• pp.139-146
• /
• 2017

This study tries to examine the effect of parents' neglect on career identity, and prove the meditating effect of experience satisfaction and school adjustment between the two variables in the times of convergence. For the study, the data from the Korean Children and Youth Panel Survey was analyzed by utilizing the path analysis, and the number of subjects was 391 adolescents. The results are as follows: First, parents' neglect influenced negatively career identity. Second, experience satisfaction and school adjustment had a positive effect on experience satisfaction. Third, parents' neglect directly influenced career identity and its' effect was indirectly mediated by the subjects's experience satisfaction and school adjustment. Therefore, the result of the study can be utilized for theoretical implication and foundation for developing programs to increase career identity.

• Journal of Convergence for Information Technology
• /
• v.7 no.3
• /
• pp.13-26
• /
• 2017

This study describes the relationship between analysis of global competencies and multiple intelligences among nursing students for the fourth industrial revolution. The survey was conducted to nursing students. and 733 samples were finally applied. Result, Global Competencies in male students significantly higher than women students. There were statically significant association between Global Leader Competency and Multiple Intelligence. Conclusion: This study showed multiple intelligence had relation with Global Leader Competency Therefore, strategy needs to reflect nursing curriculum and education program in nursing students.

• Journal of Convergence for Information Technology
• /
• v.7 no.3
• /
• pp.111-116
• /
• 2017

This study offers the possibility as a new product of souvenirs from cultural tourist sites with virtual reality contents, instead of a simple exhibit. Users can watch augmented reality contents on souvenirs, and use the virtual experience service of cultural tourist sites with VR viewer. It has 4K-class high-quality $360^{\circ}$ image capture to increase the immersion of users in virtual space, implement virtual reality space and intuitive UI interaction with users using IMU (Inertial Measurement Unit). It is also possible to apply various add-on functions, including 3D contents, through technical development to increase its marketability, and apply in other industries. In addition, the prototype of the souvenir and VR viewer will be made by using a 3D printer and such in order to apply the contents which will be introduced in this study. Various product expansions can be considered through consultation with the relevant companies for the use of ready-made products.