• Proceedings of the Korean Society of Veterinary Pathology Conference
• /
• 2003.10a
• /
• pp.48-48
• /
• 2003

Mammary cancer is the most common malignant neoplasm in the bitch. It constitute 40 percent of all tumors in female dogs, which is three times higher than incidence of mammary tumors in humans[2]. Cytological differentiation between benign and malignant canine mammary tumors is difficult, however, an irregular chromatin pattern was reported to be a significant criterion for malignancy[1]. It can be estimated that approximately 30 percent of the surgically removed mammary tumors are malignant[4]. Malignant mammary tumors often have some degree of infiltrative/destructive growth into adjacent tissues and/or invasion of vessels. Malignant mammary tumors often metastasize into local lymph nodes and lungs, and less frequently into other organs[3]. Based on histological and cytological criteria, this case was diagnosed as tubulopapillary carcinoma of the mammary gland. (omitted)

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.22 no.1
• /
• pp.209-211
• /
• 2008

Aggressive angiomyxoma is a rare neoplasm that arise from soft tissue of the perineum and usually affects young woman. It has a high risk of local recurrence due to infiltrative lesion. This tumor should be distinguished from benign and malignant tumor or tumor like lesion of the perineum. We experienced a case of an aggressive angiomyxoma on soft tissue of the vaginal wall in 43-year-old woman and reported it with a brief review of literature.

• Korean Journal of Head & Neck Oncology
• /
• v.13 no.2
• /
• pp.256-259
• /
• 1997

The fibromatoses are defined as a group of non encapsulated, non metastasizing, fibrous tumors that have a tendency for infiltrative growth and local recurrence following surgical excision and can be divided into fascial and musculoaponeurotic fibromatoses. Infantile fibromatosis is childhood counterpart of musculoaponeurotic fibromatosis and is more common in the head and neck, the shoulder and upper arm and the thigh. Treatment includes excision, radiation, steroid and chemotheraphy, etc. Treatment of choice is complete excision but postoperative deformity and sequelae should be considered. Recently, we have experienced a case of infantile fibromatosis originating from infratemporal fossa and report this case with a review of literatures.

• The Journal of the Korean dental association
• /
• v.27 no.8 s.243
• /
• pp.697-702
• /
• 1989

악성종양은 상피성의 암종(carcinoma)과 결체직성의 육종(sarcoma)으로 분류된다. 최근 암환자의 발생은 점차 증가되는 추세이며, 우리나라에서도 사망원인 중 뇌졸증 다음으로 암이 차지하는 비율이 높다. 이러한 암은 침윤성(infiltrative)인 성장으로 인하여 인접 정상조직을 급격히 파괴시키며, 해당 임파절을 따라 신체 다른 부위로 전이(metastasis)된다. 임파절에 전이되기 전에 조기발견된 암은 70%의 5년 생존률을 보이는 반면, 임파절에 전이된 후에 발견된 암은 30%의 5년 생존률을 보인다. 따라서 암의 성공적인 치료를 위해서는 이의 조기발견이 매우 중요하다고 할수 있다. 그러나 불행하게도 많은 환자가 이미 병소가 상당히 진행된 상태에서 내원하기 때문에 이의 근치가 어려우며, 예후 또한 좋지 않다. 이러한 암을 조기발견하기 위해서는 환자 자신의 관심뿐만 아니라 치과의사의 세심한 검진이 필요하리라 생각된다.

• Journal of Korean Foot and Ankle Society
• /
• v.24 no.3
• /
• pp.124-127
• /
• 2020

Intramuscular lipomas are benign adipose tumors of the soft tissues that may resemble liposarcomas because of their size, deep location, and occasionally infiltrative growth. An awareness of their existence is fundamental to treating them correctly, and their differential diagnosis from liposarcoma is essential. Magnetic resonance imaging (MRI) is a useful diagnostic tool to differentiate benign adipose tumors from liposarcoma. Marginal excision and biopsy are required for the definite diagnosis and the treatment of symptomatic intramuscular lipomas. To the best of the authors' knowledge, this is the first report in South Korea regarding the treatment of an intramuscular giant lipoma of the ankle.

• Imaging Science in Dentistry
• /
• v.32 no.4
• /
• pp.231-234
• /
• 2002

The odontogenic myxoma is an infiltrative benign tumor of bone that occurs almost exclusively in the jaw bones and comprises 3% to 6% of odontogenic tumors. This neoplasm is thought to arise from the primitive mesenchymal structures of a developing tooth, including the dental follicle, dental papilla, or periodontal ligament. Radiographically the odontogenic myxoma may produce several patterns: unicystic, multilocular, pericoronal, and radiolucent-radiopaque, making the differential diagnosis difficult. In this report, two cases of the odontogenic myxoma in the jaw bones are presented. The first case involved only the mandible, while the second case involved the maxilla. Both cases presented extensive multilocular radiolucencies characteristic of odontogenic myxoma.

• Tuberculosis and Respiratory Diseases
• /
• v.39 no.6
• /
• pp.554-558
• /
• 1992

A 38 years old man had been treated as a pulmonary tuberculosis by the positive result of acid fast stain of bronchial washing from the focal infiltrative lesion at left lower lobe. On radiologic examination after one year treatment, there was an aggravation of lesion at left lower lobe with moderate amount of pleural effusion at the same side. After 11 weeks, follow up chest film disclosed bilateral pleural effusion. The pleural fluid of both side was pus in gross appearance with low pH, high LDH, low glucose and high protein. Pleurodectomy was performed to remove the loculated empyema with the thickened pleura of right thorax. This pleuro-pulmonary lesion can be easily misdiagnosed as a tuberculous lesion if it is not taken into consideration as a possible diagnosis.

• Korean Journal of Veterinary Research
• /
• v.59 no.1
• /
• pp.51-54
• /
• 2019

Pulmonary masses were observed in the thoracic cavity of a 9-year-old female Korean native cattle (Hanwoo) encountered at a Jeju, Korea slaughterhouse. Grossly, the thoracic cavity was filled with pulmonary masses. Histologically, the neoplastic masses were composed of many abnormal papillary structures lined by single to double columnar neoplastic cells and formed arborizing fronds supported by significant fibrovascular stroma. The neoplastic cells showed strong destructive and infiltrative growth to adjacent tissues and were strongly positive for pan-cytokeratin (CK), CK 7 and sporadically positive for CK MNF116. The masses in the female Hanwoo were diagnosed as a papillary pattern of pulmonary adenocarcinoma.

• Journal of Gastric Cancer
• /
• v.21 no.2
• /
• pp.213-219
• /
• 2021

Plexiform fibromyxoma (PF) of the stomach is a very rare mesenchymal tumor of the gastrointestinal tract. We report the first case of PF with 2 different growth patterns pathologically confirmed after surgical resection. The tumor was characterized microscopically as infiltrative; it demonstrated diffuse growth into the smooth muscle bundles of the muscularis propria and was also multinodular and plexiform within the myxoid stroma. Immunohistochemical analysis revealed that the tumor cells were positive or weakly positive for smooth muscle actin, vimentin, and H-caldesmon and negative for desmin, CD117, CD34, CK-20, Pan-CK, Dog1, S100, ER, PR, and CD10. No mutations of C-kit and platelet-derived growth factor receptor alpha were detected. No genetic disruption of glioma-associated oncogene homolog 1 was detected by fluorescence in situ hybridization. The final diagnosis of PF was mainly based on the morphological and immunohistochemical findings.

• Journal of Veterinary Clinics
• /
• v.38 no.6
• /
• pp.274-278
• /
• 2021

An 11-year-old, intact female, Miniature Poodle presented with an abdominal mass. The abdominal mass was located around the right fifth mammary gland. The surgically removed mammary mass was subjected to histopathological examination. Based on the microscopic interpretation, a final diagnosis of an intermediate grade infiltrative mammary comedocarcinoma was established. Computed tomography for metastasis evaluation after surgical resection of the tumor showed enlarged right medial iliac and right inguinal lymph nodes, and a micronodule in the accessory lung lobe, suggesting metastasis of the mammary gland tumor. Doxorubicin, a chemotherapeutic drug, was administered six times at three week intervals. However, despite chemotherapy, the masses around the fourth and fifth mammary gland on the right side enlarged in size, and the treatment was discontinued at the request of the owner. The anticancer response to mammary comedocarcinoma is poor and the patient is in hospice management. This is the first attempt to treat a case of canine mammary comedocarcinoma in South Korea.