• Maxillofacial Plastic and Reconstructive Surgery
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• 제18권1호
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• pp.164-174
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• 1996

In order to develop the allogeneic bone implants instead of autogenous bone grafts for maxillofacial reconstruction, undemineralized freeze-dried human bone was processed. The freeze-dried human bone was implanted into the cranial and mandibular defects of the rabbits. The implants were evaluated clinically, roentgenographically and histomophometrically. And immunohistochemical evaluation of the implants was performed on the rat. The results were as follows : 1. When compared with control defects of $0.8{\times}0.8\;cm$, the implants on the rabbit defects displayed complete osseous bridging clinically and roentgenographically. Histomophometrically a minimal inflammatory cell infiltrate was present but the defects healed well clinically. 2. When compared with control grafts, the freeze-dried implants on the rat muscle displayed decreased antigenicity by immunohistochemical evaluation, due to freeze-drying process. 3. Undemineralized freeze-dried human bone in this study can be preserved as a bank bone in this study and seems to be applicable for clinical allogeneic bone grafts.

• Journal of Chest Surgery
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• 제54권5호
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• pp.408-411
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• 2021

Tuberculosis (TB)-infected giant bullae are rare. A 55-year-old man was referred when an infected bulla did not respond to empirical treatment. Computed tomography showed a giant bulla in the right upper lobe with an air-fluid level and surrounding infiltrate. Sputum culture, acid-fast bacilli (AFB) stain, and polymerase chain reaction (PCR) for TB were negative. Percutaneous drainage of the bullous fluid was performed. AFB stain and PCR were positive in the drained fluid. The patient was given anti-TB drugs and later underwent obliteration of the pulmonary cavity using talc. To summarize, we report a patient with a TB-infected giant bulla that was treated successfully with anti-TB drugs and obliteration of the pulmonary cavity using talc.

• Tuberculosis and Respiratory Diseases
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• 제45권6호
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• pp.1199-1213
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• 1998

연구배경 : 최근 면역기능저하 환자들이 급증하고 있으며 이들에 있어서 새로 발생된 설명이 불가능한 폐침윤은 매우 흔하면서도 환자의 생명을 위협할 수 있는 상황으로 발전할 수 있다. 폐진균증은 이런 임상상에서 폐침윤의 중요한 원인으로 대두되고 있으나 이에 대한 연구가 많지 않아 본 연구를 시행하였다. 방 법 : 1996년 10월부터 1998년 4월까지 삼성서울병원에서 면역기능저하 환자 중 새로운 폐침윤이 있었던 환자로 조직학적으로 폐에서 진균이 증명되었거나 정상적으로 균이 자리지 않는 부위(sterile)에서 시행한 배양검사장 진균이 배양된 환자들을 대상으로 임상적 특정, 방사선학적 소견, 진단적 검사, 치료 및 그 결과에 대해 후향적인 조사를 시행하였다. 결 과 : 총 13명의 환자 (M : F=8 : 5, 연령 중앙값 47세)에서 14예의 폐진균증이 진단되었다. 진단은 asperogillosis가 12예였고 mucormycosis가 2예였다. 혈액암 환자 9명에서 10예, 장기이식 환자에서 4예의 폐진균증이 진단되었다. 3예에서는 진단당시 경험적 amphotericin B를 중앙값 9일(8-21일)간 투여받고 있었다. 혈액암군 10예 중 9예에서 폐침윤 발견당시 백혈구 감소증이 중앙값 16일동안 지속되었으며 발열(9/10), 기침(6/10), 가래(5/10), 호흡곤란(4/10), 흉통 (5/10), 악설음(4/10) 등의 증상과 징후가 흔하게 관찰되었다. 반면에 장기이식환자군에서는 증상 및 징후가 뚜렸하지 않은 경우가 많았다(p<0.05). 단순 흉부촬영상으로 새로운 폐침윤은 단일 혹은 다발성의 결절(6/14)이나 경결(consolidation)(8/14)의 형태로 나타났으며 흉부 단층촬영상에서는 간유리음영(14/14), 흉수(5/14), 동공형성(7/14) 등의 소견이 관찰되었다. 확진한 방법으로는 개흉술이 10예, 비디오 흉강경술이 2예, 경피적침흡인술이 1예, 농양의 농 배양검사가 1예였다. 모든 환자는 amphotericin B(591-2806mg) 투여를 받았으며 1예에서 liposomal amphotericin B, 1예에서 경구 itraconazole로 치료를 부분적으로 시행하였다. Amphotericin B 투여 후 12/14예에서 폐병변의 호전이 관찰되었으며 14예중 4예에서 사망하거나 회복이 불가능한 상태로 퇴원하였다. 결 론 : 혈액암의 치료로 과립구감소증이 있는 환자나 장기이식 환자에서 새로운 폐침윤이 결절이나 경결의 형태로 발현하면, 증상이 미미하거나 경험적 amphotericin B를 투여하고 있더라도 폐진균증을 의심을 해야하며 적극적인 진단과 치료로써 예후를 호전시킬 수 있을 것으로 기대된다.

• Tuberculosis and Respiratory Diseases
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• 제46권2호
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• pp.273-280
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• 1999

저자들은 소세포 폐암으로 확진된 환자에서 오심 구토 혈변등 위장관 증상을 호소하여 상부 위 내시경 검사 및 조직 생검을 시행하여 위장으로의 전이를 확인한 2 예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• 한국재난정보학회 논문집
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• 제18권3호
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• pp.581-588
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• 2022

연구목적: 본 연구에서는 석탄 심부 화재 발생 시 대응과 침윤소화약제의 실효성 확대를 위한 기술기준 개선방안을 제시하고자 하였다. 연구방법: 석탄 8톤과 침윤소화약제 3종, 소화용수를 활용하여 침투 실험을 수행하고, 국내·외 기술기준 및 해외 사례를 분석하였다. 연구결과: 소화용수는 높은 표면장력으로 인해 석탄 심부로 침투하지 못하였고, 침윤소화약제는 5~25cm 깊이까지 침투되었다. 국내 기술기준은 침투성에 대한 간접 측정 방식인 표면장력만 언급되어있고, 소화능력시험도 목재를 활용하는 것으로 확인되었다. 반면 해외에서는 면직물을 활용한 심부 화재 실험, 헵탄을 이용한 B급 화재 실험이 있는 것을 확인하였다. 그 외, 미 광산국에서는 모세관 상승 시험, 침전시험, 접촉각 측정이 있는 것으로 분석되었다. 결론: 미국 NFPA 및 광산국의 기준과 사례를 토대로 국내 기술기준도 침투성을 직접적으로 측정할 수 있는 기준을 추가하여 실효성을 확대할 필요가 있을 것으로 사료된다.

• Applied Microscopy
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• 제12권1호
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• pp.41-47
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• 1982

Mycosis fungoides is an uncommon, chronic fatal disease of lymphoreticular system associated with primary ski3 involvement for many years and terminating as a malignant lymphoma with involvement of lymph nodes and viscerae. On occasion it simulates numerous other nonspecific benign skin lesions, thus it may be impossible to decide whether the infiltrate represents early mycosis fungoides or nonspecific on the histopathologic ground alone. A case of mycosis fungoides was confirmed by electron microscopy and reported here. The patient was 69-years-old male who had suffered from erythematous scaly eruption on the whole body since 10 years. Skin biopsies of 4 times showed focal ulceration with chronic nonspecific inflammation and polymorphic cell infiltration in lower dermis, thus possibility of mycosis fungoides could not be completely ruled out. Electron microscopically several atypical lymphoid cells, which had a large cerebriform nucleus with peripheral condensation of dense chromatin and scant cytoplasm, were noted in the upper dermis. Intraepidermal infiltration of these atypical cells was also seen. It was thought that the electron microscopic study may be very helpful to differentiate equivocal mycosis fungoides from the nonspecific dermatosis.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제17권2호
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• pp.116-120
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• 2014

Inflammatory myofibroblastic tumor (IMT) is rare mesenchymal solid tumor that consists of proliferating myofibroblasts with an inflammatory infiltrate background. It has a very low prevalence in infants and occurs mainly in children and young adults. IMT are mainly located in the thoracic cavity, but intra-abdominal lesions are rare. IMT can exhibit locally aggressive neoplastic processes and metastases similar to malignancies, so, have clinical importance. Herein, we describe two infantile intra-abdominal IMT cases presenting with incidentally found palpable abdominal mass. A 4-month-old male infant had IMT at the ileal mesentery and a 5-month-old male infant had IMT at liver. Both cases were successfully treated by complete surgical resection without complication or recurrence. Considering the biological behavior of the intermediate type of neoplasm in IMT, we expect good survivals when achieving appropriate surgical resection without adjuvant therapy in infantile intra-abdominal IMT.

• 한국환경복원기술학회지
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• 제11권6호
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• pp.1-10
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• 2008

The study was aimed at analyzing the relationship between the characteristics of urban green infrastructure and stormwater runoff in a small urban watershed composed of 22 drainage basins. The green areas of which soils are not sealed and allow water infiltrate, were examined for different types of green spaces. In a comparative study for drainage basins of which green spaces are 15.5% and 34.4%, respectively, runoffs were not different with the size of green space. It was attributed to that the increase of runoff by greater road area offset the advantage of greater green area. Another comparative measurement of runoff for drainage basins with similar green area size showed that runoff decreased with greater permeable area (school ground area) and smaller road area. The runoff measurements could address that runoff rates are affected not only by green area size but also by the type of green area and other land covers related to permeability and flow into drainage. It implicated that the improvement of urban green infrastructure as a functional unit for water infiltration and interception is important for stormwater runoff management.

• 대한기계학회논문집A
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• 제27권7호
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• pp.1051-1057
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• 2003

This study is about controlled impurities, which make metal alloys, especially AC4CH alloy that is made by restraining 0.2％ Fe and Aluminum to make a matrix material. A metal matrix composite is produced using the squeeze casting method. The first step in the squeeze casting method is to add some organic binder including aluminum borate whisker into the matrix. After the fabrication of a metal matrix composite, each is individually appended to an inanimate binder such as SiO$_2$, Al$_2$O$_3$, and TiO$_2$. Through experiments the mechanical property changes were investigated between the metal matrix composite and AC4CH alloy. This study proves the superiority of the mechanical property of a metal matrix composites over AC4CH according to the previous tests and results that were mentioned above. One excellent property of matrix material composites is the infiltrated TiO$_2$ reinforcement. This material is a good substitute for the existing materials that are used in the development of industries today.

• Tuberculosis and Respiratory Diseases
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• 제51권3호
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• pp.275-280
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• 2001

Background : A 18 year-old man presented with dyspnea and a swelling of the neck. On physical examination, maculopapular rashes were noted on the face and the whole body and crepitus was noted at the thorax and upper arms. His chest X -ray showed bilateral interstitial infiltrates of the lung, pneumomediastinum and subcutaneous emphysema. On serologic examination, measles IgM was positive. Under the diagnosis of measles pneumonia, the patient was treated with oral ribavirin, which resulted in a complete resolution of the pneumomediastinum, subcutaneous emphysema, pneumonic infiltrate, and subjective symptoms of dyspnea and swelling of the neck in 7 days. Here we report this case with a brief review of the relevant literature.