• Tuberculosis and Respiratory Diseases
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• 제76권2호
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• pp.80-83
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• 2014

Patients with acquired immunodeficiency syndrome (AIDS) are at higher risks of bacterial pneumonia than the general population, and the pathogen is the most commonly involved Streptococcus pneumoniae. We hereby report a case of pneumococcal pneumonia associated with leptomeningitis, osteomyelitis and epidural abscess in a patient with AIDS. He is being successfully treated with ampicillin/sulbactam and clindamycin. And because the pneumococcal infection is usually associated with morbidity and mortality rates in the setting of AIDS, we should consider for pneumococcal vaccinations among the AIDS populations.

• Clinical and Experimental Pediatrics
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• 제54권4호
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• pp.141-145
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• 2011

Pertussis is an acute respiratory infection characterized by paroxysmal cough and inspiratory whoop for over 2 weeks. The incidence of pertussis has decreased markedly after the introduction of DTwP/DTaP vaccine, but the incidence of pertussis has increased steadily among young infant and among adolescents and adults in many countries. Td vaccine was used in this age group but the increase in pertussis has lead to the development of a Tdap vaccine. The Tdap vaccine is a Td vaccine with a pertussis vaccine added and is thought to decrease the incidence and transmission of pertussis in the respective age group. In Korea, two products are approved by the KOREA FOOD & DRUG ADMINISTRATION, which are ADACEL$^{TM}$ (Sanofi-Pasteur, Totonto, Ontario, Canada) and BOOSTRIX$^{(R)}$ (GlaxoSmithKline Biologicals, Rixensart, Belgium) for those aged between 11-64. This report summarizes the recommendations approved by the Committee on Infectious Diseases, the Korean Pediatric Society.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 2001년도 제53차 추계 학술대회 연제집
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• pp.294-295
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• 2001

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 2001년도 제53차 추계 학술대회 연제집
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• pp.292-293
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• 2001

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 2001년도 제53차 추계 학술대회 연제집
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• pp.283-284
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• 2001

• 한국보건간호학회지
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• 제33권3호
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• pp.326-339
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• 2019

Purpose: This study attempts to identify the level of awareness, ethical awareness, and decision-making among nursing students, in response to pandemic infectious diseases. Methods: Subjects were 210 nursing college students attending colleges in 5 cities and provinces nationwide. Data were collected from November 2017 to April 2018 using a self-administrated questionnaire, and analyzed utilizing descriptive statistics. Results: Considering the awareness of pandemic infectious diseases, the nursing students expressed high concern about the possibility of future outbreaks of pandemic infectious diseases and seriousness of the situation. There were numerous negative views on the response and stockpiling of drugs by the government. Ethical awareness of pandemic infectious diseases was high, with demands for accurate information and proper protective equipment. Overall, ethical decision-making when responding to pandemic infectious diseases represented a high score. Also, higher awareness levels of pandemic infectious diseases would result in increased ethical and ethical decision-making. Conclusion: In conclusion, we propose the introduction of an ethical education program for medical personnel and nursing university students, to enable the handling of future pandemic outbreaks of new infectious diseases.

• Child Health Nursing Research
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• 제27권1호
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• pp.56-64
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• 2021

Purpose: This study investigated the practices of preventing infectious diseases by daycare center teachers. The focus was on the mediating effects of self-efficacy in the relationship between communication skills and practices of preventing infectious diseases. Methods: This study used a descriptive correlational design. The participants were 164 daycare center teachers. Hierarchical regression was used to test the mediating effect of self-efficacy in the relationship between communication skills and practices of preventing infectious diseases. Data were analyzed using the independent t-test, one-way analysis of variance, Pearson correlation coefficients, and hierarchical regression. The mediation effect was analyzed using an SPSS Macro program, PROCESS. Results: Significant relationships were found between communication skills and practices of preventing infectious diseases (β=.19, p<.001), self-efficacy and practices of preventing infectious diseases (β=.59, p<.001), and communication skills and self-efficacy (β=.27, p<.001). Self-efficacy had a significant mediating effect (β=.17, 95% confidence interval=0.07~0.29) on practices of preventing infectious diseases. Conclusion: In order to improve practices of preventing infectious diseases among daycare teachers, it is necessary to develop and apply interventions and methods that can increase effective communication skills and self-efficacy.

• Clinical and Experimental Vaccine Research
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• 제13권1호
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• pp.21-27
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• 2024

Chronic infectious diseases refer to diseases that require a long period of time from onset to cure or death, the use of therapeutic vaccines has recently emerged to eradicate diseases. Currently, clinical research is underway to develop therapeutic vaccines for chronic infectious diseases based on various vaccine formulations, and the recent success of the messenger RNA vaccine platform and efforts to apply it to therapeutic vaccines are having a positive impact on conquering chronic infectious diseases. However, since research on the development of therapeutic vaccines is still relatively lacking compared to prophylactic vaccines, there is a need to focus more on the development of therapeutic vaccines to overcome threats to human health caused by chronic infectious diseases. In order to accelerate the development of therapeutic vaccines for chronic infectious diseases in the future, it is necessary to establish a clear concept of therapeutic vaccines suitable for the characteristics of each chronic infectious disease, as well as standardize vaccine effectiveness evaluation methods, secure standards/reference materials, and simplify the vaccine approval procedure.

• 대한수의학회지
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• 제57권3호
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• pp.155-158
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• 2017

Surgical castration performed to reduce male-associated problems results in pain and microbial infections in male animals. Therefore, immunocontraception, which is mediated by the animal's own antibodies against reproductive hormones, has been recommended as an alternative to surgical castration when considering the animal's welfare. In this study, a new immunocontraceptive vaccine composed of six tandem copies of gonadotropin-releasing hormone (GnRH) fused to rat granulocyte-macrophage colony-stimulating factor (GM-CSF) was developed, and its efficacy was evaluated in male rats. Three different doses (10, 50, and $100{\mu}g$) of recombinant GM-CSF-GnRH protein were injected three times at intervals of two weeks into male rats. The rats vaccinated with three doses of GM-CSF-GnRH produced a significantly higher level of antibodies against GnRH than that in the negative control rats. Severe atrophy of gonads was observed in rats vaccinated with three doses of GM-CSF-GnRH but not in the negative control rats. The results reveal that the new GnRH vaccine conjugated with rat GM-CSF induces efficient immunocontraception in male rats. This formulation of the immunocontraceptive vaccine would be applicable to both domestic and pet male animals.

• 한국콘텐츠학회논문지
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• 제21권3호
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• pp.561-566
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• 2021

학교는 감염병 발생 시 광범위하게 확산될 우려가 높은 집단이며, 학생들의 건강과 학습권을 저해할 수 있으므로 체계적인 관리와 신속한 대응이 필요하다. 본 연구는 초·중·고 학생들에게 흔히 발생하는 감염병의 현황을 파악하여 감염병의 위협으로부터 학생과 교직원을 보호하고 정상적인 학교 기능을 유지하기 위한 기초자료를 제공하기 위해 실시하였으며, 조사 대상으로는 세종시를 선정하였다. 3대 감염병은 인플루엔자, 수두, 수족구병으로서, 3대 감염병 모두 급성 바이러스성 감염병으로 분류되며 전파속도가 빠르고 전파력이 강한 특징이 있어 집단 생활을 하는 학생들에게는 치명적인 결과를 초래할 수 있다. 연구자료는 교육부 교육행정정보망인 나이스(NEIS)의 2019년도 감염병 보고자료를 활용하였고, 전국 초·중·고등학교에서 매주 보고된 현황 자료를 활용하여 분석하였으며, 연구방법으로는 전국과 세종시 감염병 발생 현황 비교, 각 학교급별 발생 현황 비교, 감염병 항목별 발생 현황 비교, 시기별 감염병 현황 분석을 실시하였다. 3대 감염병 발생 현황 조사 결과는 세종시 뿐만 아니라 전국 학교감염병의 감염병을 관리하는데 기초자료로 사용되어, 향후 학교감염병 관리 대책 수립에 활용할 수 있도록 기대한다.