• Journal of Korean Neurosurgical Society
• /
• 제53권3호
• /
• pp.197-200
• /
• 2013

Diagnosis of cerebral syphilitic gumma is frequently determined at the time of surgery, because imaging and laboratory findings demonstrate the elusive results. A 59-year-old woman presenting dysarthria showed a mass on her brain computed tomography. She was first suspected of brain tumor, but histological results from surgical resection revealed cerebral gumma due to neurosyphilis. After operation, she presented fever and rash with an infiltration on a chest X-ray. Histological assessment of skin was consistent with syphilis. Fluorescent treponemal antibody absorbed test IgG in cerebrospinal fluid was positive. She was successfully treated with ceftriaxone for 14 days.

• Parasites, Hosts and Diseases
• /
• 제50권3호
• /
• pp.253-257
• /
• 2012

Natural habitat fragmentation and reducing habitat quality have resulted in an increased appearance of Japanese macaques, Macaca fuscata (Gray, 1870), in suburban areas in Japan. To investigate the risk of zoonotic infections, a coprological survey of helminth eggs passed by wild Japanese macaques was carried out in 2009 and 2010 in Shiga Prefecture, Japan. Microscopic examination found helminth eggs in high prevalence, and nucleotide sequencing of DNA extracted from the eggs identified Oesophagostomum cf. aculeatum and Trichuris trichiura. A fecal culture also detected infective larvae of Strongyloides fuelleborni. These zoonotic nematodes pose a potential health issue to local people in areas frequented by Japanese macaques.

• Parasites, Hosts and Diseases
• /
• 제56권6호
• /
• pp.597-602
• /
• 2018

Histomonas meleagridis is a facultative anaerobic parasite, which can cause a common poultry disease known as histomoniasis. The species and age of the birds impacts on the susceptibility, with turkey being the most susceptible species. Chickens are less susceptible to H. meleagridis than turkeys and usually serve as reservoir hosts. Here, the diagnosis of an outbreak of histomoniasis in backyard Sanhuang chickens is described. The primary diagnosis was made based on clinical symptoms, general changes at necropsy, histopathology, and the isolation and cultivation of parasites. The pathogen was further confirmed by cloning, PCR identification, and animal inoculation tests. A strain of H. meleagridis, named HM-JSYZ-C, with a higher pathogenicity level in chickens was obtained. The study lays a foundation for further investigations into H. meleagridis and histomoniasis in chickens.

• Parasites, Hosts and Diseases
• /
• 제59권4호
• /
• pp.399-402
• /
• 2021

The COVID-19 pandemic continues to be a major health problem worldwide. Timely diagnosis of co-infections mimicking COVID-19, such as malaria, might be challenging particularly in non-endemic areas. We report the first case of COVID-19 and Plasmodium ovale malaria co-infection from our region aiming to highligt the importance of travel history and prophylaxis in malaria management in the context of pandemic. The galloping sound can sometimes be a harbinger of zebra besides the horse.

• Clinical and Experimental Pediatrics
• /
• 제65권4호
• /
• pp.167-171
• /
• 2022

In the era of the coronavirus disease 2019 (COVID-19) pandemic, countries worldwide have implemented several nonpharmaceutical interventions (NPIs) to contain its spread before vaccines and treatments were developed. NPIs included social distancing, mask wearing, intensive contact tracing and isolation, and sanitization. In addition to their effectiveness at preventing the rapid spread of COVID-19, NPIs have caused secondary changes in the epidemiology of other infectious diseases. In Korea, various NPI stages have been implemented since the first confirmed case of COVID-19 on January 20, 2020. This review, based on a PubMed database search, shows the impact of NPIs on several infectious diseases other than severe acute respiratory syndrome coronavirus 2 in the COVID-19 pandemic era in Korea.

• 한국입자에어로졸학회지
• /
• 제6권2호
• /
• pp.81-90
• /
• 2010

Several studies have suggested the possibility of airborne transmission of infectious diseases such as tuberculosis, pandemic influenza. because the number of patients increases explosively, if infectious disease had a high basic reproduction number, pharmaceutical interventions such as vaccination, chemoprophylaxis in the early stage of epidemic. Thus, non-pharmaceutical interventions such as mask-wearing, installing air cleaners, school closure are important to control and prevent the infectious diseases. However, the current technology on the mask, air cleaning, ventilation, and etc., seems to be not originated from the understanding of infection via airborne transmission. It is important to estimate the aerodynamic behavior of saliva droplets by coughing or speaking in order to understand the phenomena of airborne infection. In addition, the prediction of transmission of infectious diseases through the air is critical to prevent or minimize the damage of infection. In this review, we reviewed the recent studies on the airborne infection by focusing on the aerodynamic characteristics of saliva droplets and modeling of airborne transmission.

• 대한물리의학회지
• /
• 제16권1호
• /
• pp.123-141
• /
• 2021

PURPOSE: Focusing on the factors that influence the infectious disease emergency response policy (approached by dividing the factors into health policy management and economic policies), both SARS and MERS cases were based on the legal system, manpower, and budget, but there has not been enough learning from the epidemic. This study focused on infectious disease emergency governance, which various studies have neglected despite its social and academic importance. METHODS: The research is based on an analysis of SARS, MERS, and COVID-19 and compares global policies. In this study, infectious disease emergency governance was divided into health policy management and economic factors. This study focused on planning and leadership before and after the outbreak of infectious diseases and how cooperation was achieved to monitor and respond to infectious diseases successfully. RESULTS and CONCLUSION: The limit of this study was that COVID-19 is a currently ongoing infectious disease with high uncertainty. Because it is an ongoing problem, only some data and statistics are reflected, and many limitations prevent a proper comparison under the same criteria as other infectious diseases. In addition, because continuous changes are expected, there is also room for infectious diseases to develop in a completely different pattern from the current situation, and continuous research must be accompanied in the future.

• 대한미생물학회지
• /
• 제35권5_6호
• /
• pp.372-372
• /
• 2000

• 한국화재소방학회논문지
• /
• 제31권3호
• /
• pp.144-150
• /
• 2017

국가 간 교류 확대와 기후변화 등으로 감염병의 국내유입도 증가하고 있는 추세이다. 또한 사회적 환경변화로 감염병 발생 가능성의 증가에 대한 국민적 관심과 불안은 크게 증가하고 있다. 이러한 감염병 발생은 경제에도 심각한 위협이 되고 있으므로 감염병 예방과 확산 방지를 위한 다각적인 노력이 필요하다. 현재 많은 의료 기관에서는 전염병이 발생했을 때, 질병관리본부 등 상급 기관으로의 신속한 보고가 매우 중요하며 또한 일반 환자와 감염된 의심환자를 공간적으로 나누는 시설이 여의치 않아 병원 내에서 감염이 확대될 위험성이 높은 편이다. 본 연구에서는 감사원의 중동증후군(MERS)의 감사 결과를 토대로 감염병 발생 보고, 감염자의 분리 방법 및 감염 확대를 막는 방법 등을 고찰하여 예방 및 확산 방지를 위한 개선방안에 대해서 연구하였다.

• Biomolecules & Therapeutics
• /
• 제11권3호
• /
• pp.178-182
• /
• 2003

The clinical use of once daily aminoglycoside (ODA) dosing has been increased because of the potential therapeutic advantages of this dosing regimen. To evaluate the optimal sampling times of ODA dosing method in a clinical setting, the study was prospectively conducted in a total of 28 patients with UTI. All of the patients were intravenously administered gentamicin at a dose of 7 mg/kg over 60 minutes and randomly divided into two groups. Blood was collected at 0, 2, and 6 hours in Group A and at 1, 2, and 6 hours in Group B after the end of 1-hour infusion. The pharmacokinetic parameters (Ke, Vd and Cmax) obtained using the 0, 6 hour levels and 2, 6 hour levels in Group A were statistically different while those of 1, 6 hour levels and 2, 6 hour levels in Group B were similar. This finding indicated that the distributional phase of ODA is completed within 1 hour following the end of the I-hour infusion. If we are allowed to collect only two blood samples in ODA considering patients comfort and the analytical cost of drug, the first one should be drawn after 1 hour following the end of infusion to obtain adequate pharmacokinetic information.