• Tuberculosis and Respiratory Diseases
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• v.63 no.2
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• pp.145-153
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• 2007

Background: Asthma is a syndrome that is characterized by a variable degree of airflow obstruction, bronchial hyperresponsiveness, and airway inflammation. Colchicine is an inexpensive and safe medication with unique anti-inflammatory properties. IL-1Ra (Interleukin-1 receptor antagonist) mediates the anti-inflammatory effect in human inflammatory diseases, including asthma. This study examined whether IL-1Ra mediates the anti-inflammatory effect of colchicine in normal human bronchial epithelial cells (NHBE), RAW 264.7 cells (murine macrophage cell line), and a mouse lung. Methods: NHBE, RAW 264.7 cells and BALB/c mice were stimulated with colchicine, and the increase in the IL-1Ra level was estimated by ELISA, Western analysis and RT-PCR analysis. Results: Colchicine stimulated NHBE and RAW 264.7 cells to release IL-1Ra into the supernatant in a dose-and time-dependent manner. The major isoform of IL-1Ra in NHBE and RAW 264.7 cells is type I icIL-1Ra, and sIL-1Ra, respectively. IL-1Ra up-regulation was blocked by PD98059, a specific inhibitor in MAPK pathways. Colchicine also stimulated the secretion of IL-1Ra into the bronchoalveolar lavage (BAL) fluid of BALB/c mouse. Conclusion: Colchicine stimulates an increase in the IL-1Ra level both in vivo and in vitro, and might have an anti-inflammatory effect.

• Korean Chemical Engineering Research
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• v.51 no.4
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• pp.438-442
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• 2013

The study of bioproduct production from inexpensive biomass such as marine biomass has recently attracted considerable attention. Because, marine biomass which compared to land biomass, it can be grown rapidly and is easily cultivated without the need for expensive equipment. In addition, the carbohydrate contents are similar or higher than land biomass such as woody biomass and can be easily converted to chemicals through proper chemical processes. In the production of various biochemicals from marine biomass, levulinic acid is a highly versatile chemical with numerous industrial uses and has the potential to become a commodity chemical. It can be used as a raw material for resins, plasticizers, textiles, animal feed, coatings and antifreeze. In this study, experiments were carried out to determine the optimum conditions of temperature, acid concentration and reaction time for production of levulinic acid from marine biomass, Gelidium amansii, using two-step treatment. In the first hydrolysis step, solid-state cellulose which was used to produce ethanol by fermentation and liquid-state galactose which used to produce bioproduct such as levulinic aicd were obtained through acid soaking. In the second hydrolysis step, the liquid-state galactose was converted into levulinic acid via a high-temperature reaction in a batch reactor. As a result, the overall production yield of Gelidium amansii to levulinic acid in the two-step acid hydrolysis was approximately 20.6% on the initial biomass basis.

• 한국벤처창업학회:학술대회논문집
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• 2010.08a
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• pp.71-89
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• 2010

It is strongly believed that multicast will become one of the most promising services on internet for the next generation. Multicast service can be deployed either on network-layer or application-layer. IP multicast (network-layer multicast) is implemented by network nodes (i.e., routers) and avoids multiple copies of the same datagram on the same link. Despite the conceptual simplicity of IP multicast and its obvious benefits, it has not been widely deployed since there remain many unresolved issues. As an alternative to IP multicast, overlay multicast (application-layer multicast) implements the multicast functionality at end hosts rather than routers. This may require more overall bandwidth than IP multicast because duplicate packets travel the same physical links multiple times, but it provides an inexpensive, deployable method of providing point-to-multipoint group communication. In this paper we develop an efficient method applied greedy algorithm for solving two models of overlay multicast tree building problem that is aimed to construct MDST (Minimum Diameter Spanning Tree : minimum cost path from a source node to all its receivers) and MST (Minimum Spanning Tree : minimum total cost spanning all the members). We also simulate and analyze MDST and MST.

• Fashion & Textile Research Journal
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• v.12 no.3
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• pp.291-301
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• 2010

Today Korean clothing companies are experiencing difficulties in the global market due to unfavorable business conditions including poor production environments, labor shortage, rising costs, the further opening of the domestic distribution market, and increased competition among them. As a result, this has caused many of Korean clothing companies to transfer their production bases abroad in search of relatively inexpensive labor force, instead of using domestic plants. This study attempted to examine how Korean clothing companies perceive production environments and labor standards with regard to their offshore outsourcing. In such an attempt, in-depth interviews were conducted with 24 brand-name clothing firms. Those interviewed firms were the brands for the domestic or foreign market that were found to produce more than 200,000 pieces of clothing per year, and also the group of interviewees included some promotion service providers. The key findings from this study are as follows: First, a large number of the interviewed clothing companies were found to manage their foreign contract manufacturers by "visiting their factories regularly on a seasonal basis" or "stationing their personnel in factory for management purposes." Second, in relation to quality control in their foreign manufacturers, the most frequent response was to "have personnel stationed in those manufacturers." A smaller number of the clothing companies answered that they had "engaged their production management teams in quality control from time to time," or "used their inspectors to inspect products." Third, when asked about labor standards in foreign contract manufacturers, the largest number of the clothing companies responded, "we apply our own standards." The results of this study suggest that most of domestic clothing companies still use offshore sourcing just as a means of reducing their initial labor costs. However, in the continuously changing environment of the global clothing industry, clothing businesses are required to escape from the early phases of their manufacturing environments and set up more globalized standards.

• Geophysics and Geophysical Exploration
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• v.11 no.2
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• pp.153-160
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• 2008

Seismic modeling is used to simulate wave propagation in the earth. Although the earth's subsurface is usually semi-infinite, we cannot handle the semi-infinite model in seismic modeling because of limited computational resources. For this reason, we usually assume a finite-sized model in seismic modeling. In that case, we need to eliminate the edge reflections arising from the artificial boundaries introducing a proper boundary condition. In this study, we changed three kinds of boundary conditions (sponge boundary condition, Clayton and Engquist's absorbing boundary condition, and Higdon's transparent boundary condition) so that they can be applied in elastic wave modeling for anisotropic media. We then apply them to several models whose Poisson's ratios are different. Clayton and Engquist's absorbing boundary condition is unstable in both isotropic and anisotropic media, when Poisson's ratio is large. This indicates that the absorbing boundary condition can be applied in anisotropic media restrictively. Although the sponge boundary condition yields good results for both isotropic and anisotropic media, it requires too much computational memory and time. On the other hand, Higdon's transparent boundary condition is not only inexpensive, but also reduce reflections over a wide range of incident angles. We think that Higdon's transparent boundary condition can be a method of choice for anisotropic media, where Poisson's ratio is large.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.7
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• pp.239-247
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• 2014

The CTSIB (Clinical Test of Sensory Integration on Balance) using high sensitive pressure sensors is normally used to assess the sense of balance in hospital. It takes an objective measurement of the amount of sway that occurs in the body trunk by observing the change in the center of pressure (CoP) on the foot at the upright posture. In this paper, we would like to propose method to easily measure trunk sway in home. Although the Wii balance board(WBB) is used for games, it can measures the center of pressure, which is highly correlated. The Wii remote controller(WRC) is inexpensive compared to the WBB, but it has problems with estimation of trunk sway because it can't measure pressure directly like WBB. We collected data from 10 normal subjects (5 males, 5 females) from two devices in order to compare the CoP from WBB and the center of mass (CoM) from WRC. The results of WRC and WBB was similar when the data were analyzed by the convex hull and ellipse area.

• Journal of the korean academy of Pediatric Dentistry
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• v.31 no.4
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• pp.671-679
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• 2004

The purpose of this study was to develop a practical caries activity test by fluorescence using laser, plasma light and halogen light. The subjects of study were 45 children of 7-8 years old Argon laser, plasma light and halogen light were irradiated to buccal or labial surface of all teeth. Fluorescence of initial carious lesion from teeth was observed through barrier filter and the number of teeth showing lesion was counted. Visual examination for the dDfFtT, mutans streptococci screening test and Lactobacilli colony counting were also done. Data analysis was accomplished by Axelsson's method. The result from the present study can be summarized as follows. 1. Laser, plasma light and halogen light could detect the initial carious lesions better than visual examination(p<0.05). 2. There was positive correlation between laser(r=0.42), plasma light(r=0.41), halogen light(r=0.39) and dBfFtT rate(p<0.01). 3. The specificity sensitivity and predictive value was showed highest value in laser, but was showed favorable value in plasma light and halogen light. In regard to above results, laser, plasma light and halogen light all considered to be reliable method for determining individual caries activity. And they were also considered to be practical method because it would be simple, inexpensive, and time saving method.

• Journal of Dental Rehabilitation and Applied Science
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• v.28 no.4
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• pp.385-395
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• 2012

This clinical report presents the case using overlay dentures to treat a patient with cleft lip and palate and malocclusion. This patient requires vigorous treatment such as orthodontic treatment and combined orthodontic/oral surgery procedures. Overlay denture can be used as an alternative treatment option. Intraoral and radiographic examinations were done. The vertical dimension of occlusion was evaluated for proper prosthetic procedures and the surveying in the diagnostic cast was done. Considering the tissue and teeth undercut, the alterations of teeth shape were done. Final preparation and impression was performed. After the evaluation of vertical dimension and occlusion with wax-denture, the dentures were polymerized. Clinical remounting and occlusal adjustment were done on the articulator. Overlay dentures were delivered and the patient was recalled for relining. The overlay dentures satisfied patient's esthetic and functional requirements and provided a stable occlusion. Overlay dentures in this case were a reversible and relatively inexpensive treatment for this patient, however the potential possibilities of caries and periodontal disease as a result of poor oral hygiene should be prevented with periodic recall.

• Journal of Adhesion and Interface
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• v.19 no.3
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• pp.101-105
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• 2018

With the rapidly growing of the population and industrization of cities, the clean and affordable water resources have gained immense interest because of remaining about 780 million people still lack access to it. However, present wastewater treatment systems have been faced with various issues, such as low processing efficiency, high operational costs and the requirement of a large area for manufacturing. It is therefore urgently required to develop an inexpensive and efficient wastewater treatment system. As the one of these efforts, we suggested and successfully demonstrated the wastewater treatment system using and electrochemical method via a dimensionally stable anode (DSA) based on rutile type $RuO_2$. Our system achieved biochemical oxygen demand (BOD), chemical oxygen demand (COD), and total organic carbon (TOC) removal efficiently at the respective rates of 52.0%, 77.8%, and 65.6% from household wastewater. In addition, we were able to remove BOD, COD, total nitrogen (TN), and total phosphorus (TP) from animal husbandry wastewater at rates of 92.9%, 75.6%, 35.1%, and 100%, respectively, thereby achieving dramatic reductions. Considering the excellent removal efficiency and the small size of this device, electrochemical wastewater treatment using a DSA coated in rutile $RuO_2$ presents a promising option for the treatment of both household and animal husbandry wastewater.

• Journal of Korea Water Resources Association
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• v.38 no.11
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• pp.917-925
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• 2005

LSIV (Large Scale Image Velcocimetry) Is one of the image-based velocity measurement techniques. Since it measures surface velocities, it gives simple and inexpensive way to measure velocity, compared to other methods. Because of these advantages, there have been many studies to apply LSIV to the river discharge measurement in the field. Measuring the discharge by using LSIV requires a method which converts a surface velocity to a mean velocity In the present study, experiments and analysis of vortical velocity profile of open-channel flow in various conditions were performed to develop methods which estimate a mean velocity from a surface velocity. The result of this experiment reveals that velocity-dip phenomena occur at free-surface layer in open channel flow and Froude number affects more than bed roughness does. Two methods for estimating the mean velocity were proposed. One is to correct the wake law's profiles by using the difference of surface velocity from the mean velocity, and the other is to use the ratio of mean and surface velocities. The result of applying these methods in an experiment shows that they are quite accurate having an error of approximately $6\%$ only.