• Title/Summary/Keyword: Inductive effect

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Effect of n-Butyrate on the In Vitro Reactivation of Latent Herpes Simplex Virus (잠재성 Herpes Simplex Virus의 재활성화에 대한 n-Butyrate의 효과)

  • Chun, Yeon-Sook;Park, No-Hee
    • The Korean Journal of Pharmacology
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    • v.22 no.2
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    • pp.123-127
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    • 1986
  • n-Butyrate (n-BT A) increased the rate and number of infectious units produced in the in vitro reactivation of latent herpes simplex virus. While the mechanism of action of n-BT A is obscure, a continuous presence of n-BT A is necessary for its inductive effect.

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A surface resistance effect on the fabrication of Dye-sensitized Solar Cell with various widths (셀 폭에 따른 염료 감응형 태양전지의 표면저항 효과)

  • Choi, Jin-Young;Kim, Yong-Cheol;Park, Sung-Jun;Sung, Youl-Moon;Kim, Whi-Young;Kim, Hee-Je
    • 한국신재생에너지학회:학술대회논문집
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    • 2006.06a
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    • pp.187-191
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    • 2006
  • Sputter deposition followed by surface treatment was studied using reactive RF plasma as a method for preparing titanium oxide $(TiO_2)$ films on the FTO $(SnO_2: F)$ substrate for dye-sensitized solar cells (DSCs). Anatase structure $TiO_2$ films deposited by reactive RF magnetron sputtering under the conditions of $Ar/O_2(5%)$ mixtures, RF power of 600W and substrate temperature of $400^{\circ}C$ were surface-treated by inductive coupled plasma (ICP) with $Ar/O_2$ mixtures at substrate temperature of $400^{\circ}C$, and thus the films were applied to the DSCs. We have chosen a solar cell width as a variable of a large-scaled DSCs and confirmed electric characteristics of an individual cell. As a result, the higher the internal resistance of DSC becomes, the wider the width gets. Internal resistance makes it difficult to collect photoelectron generated from dye. Ultimately up sizing DSC causes the increase of internal resistance and then has a bad effect on the cell characteristics.

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Study of Corrosion of Brass Coated Steel Cords in the Acetonitrile Solution of Sulfenamide Derivatives by Tafel Plot and AC Impedance Measurements

  • Young Chun Ko;Byung Ho Park;Hae Jin Kim;Q Won Choi;Jongbaik Ree;Keun Ho Chung
    • Bulletin of the Korean Chemical Society
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    • v.15 no.2
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    • pp.122-126
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    • 1994
  • Corrosion of brass coated steel cords in the acetonitrile solution of sulfenamide derivatives, N-Cyclohexylbenzothiazole-2-sulfenamide (CBTS), N,N'-Dicyclohexylbenzothiazole-2-sulfenamide (DCBS), N-tert-Butylbenzothiazole-2-sulfenamide (TBBS), N-tert-Amylbenzothiazole-2-sulfenamide (TABS), and N-Oxydiethylbenzothiazole-2-sulfenamide (OBTS) was investigated by potentiostatic anodic and cathodic polarization (Tafel plot), DC polarization resistance, and AC impedance measurements. The corrosion current densities and rates are 1.236 ${\mu}A /cm^2$ and 0.655 MPY for CBTS; 1.881 ${\mu}A/cm^2$ and 0.988 MPY for DCBS; 2.367 ${\mu}A/cm^2$ and 1.257 MPY for TBBS; 3.398 ${\mu}A /cm^2$ and 1.809 MPY for TABS, respectively. OBTS among derivatives under study shows the lowest corrosion density (0.546 ${\mu}A /cm^2$) and the slowest corrosion rate (0.288 MPY). Also, the charge transfer resistances and the double layer capacitances are 275.21 $k{\Omega}{\cdot}cm^2$ and 7.0 ${\mu}F{cdot}cm^{-2}$ for CBTS; 14.24 ${\mu}F{\cdot}cm^2$ and 26 ${\mu}F{\cdot}cm^{-2}$ for DCBS; 54.15 $k{\Omega}{\cdot}cm^2$ and 26 ${\mu}F{\cdot}cm^{-2}$ for TBBS; 0.96$k{\Omega}{\cdot}cm^2$ and 83 ${\mu}F{\cdot}cm^{-2}$ for TABS, respectively. The weaker the electron donating inductive effect of derivatives is and the smaller the effect of steric hindrance is, the more the corrosion of brass coated steel cords in the acetonitrile solution of sulfenamide derivatives is prevented. The above results agree with that observed in the field of tire industry.

Asterisk(*) Array structure based power reduction power distribution board (애스터리스크(*) 배열구조 기반 전력저감 수배전반)

  • Kim, Mi-Suk;Park, Dong-Sam
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.11
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    • pp.138-144
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    • 2017
  • With the increase in power consumption due to the surge in the demand for power, it is necessary to improve the quality or design of the power (supply) for the purpose of reducing the energy consumption and so reduce the power loss. The switchboard is a mechanical device that receives electricity from the electricity generation facilities of KEPCO and divides it into the facilities required for each building. Switchboards generally consist of enclosures, switches, power conductors, and control components. This study deals with energized power conductors, which constitute the main element in the switchboard. Through the measurement of the effective ac resistance, it was confirmed that the vertical array structure of the conventional type plate conductor is inefficient. If the effective AC resistance increases significantly, the sectional area of the conductor becomes relatively large due to the skin effect. In this study, we studied the energy and material savings that could be obtained using the asterisk (*) array structure, which minimizes the effective ac resistance by reducing the skin effect. The core technology principle of this study is the energy saving switchgear based on conductor resistance reduction technology utilizing the asterisk array structure. The present invention involves a plate-shaped conductor arrangement structure capable of canceling out the magnetic field generated on each of the plate conductors (rst or abc) of the AC power supply in the power distribution panel by mutual action. The effect of this structure is to reduce the amount of inductive reactance due to the increase in the cross-sectional area and reduction of the effective AC resistance.

Development of Instructional Models for Problem Solving in Quadratic Functions and Ellipses (이차함수와 타원의 문제해결 지도를 위한 멀티미디어 학습자료 개발)

  • 김인수;고상숙;박승재;김영진
    • Journal of Educational Research in Mathematics
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    • v.8 no.1
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    • pp.59-71
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    • 1998
  • Recently, most classrooms in Korea are fully equipped with multimedia environments such as a powerful pentium pc, a 43″large sized TV, and so on through the third renovation of classroom environments. However, there is not much software teachers can use directly in their teaching. Even with existing software such as GSP, and Mathematica, it turns out that it doesn####t fit well in a large number of students in classrooms and with all written in English. The study is to analyze the characteristics of problem-solving process and to develop a computer program which integrates the instruction of problem solving into a regular math program in areas of quadratic functions and ellipses. Problem Solving in this study included two sessions: 1) Learning of basic facts, concepts, and principles; 2) problem solving with problem contexts. In the former, the program was constructed based on the definitions of concepts so that students can explore, conjecture, and discover such mathematical ideas as basic facts, concepts, and principles. In the latter, the Polya#s 4 phases of problem-solving process contributed to designing of the program. In understanding of a problem, the program enhanced students#### understanding with multiple, dynamic representations of the problem using visualization. The strategies used in making a plan were collecting data, using pictures, inductive, and deductive reasoning, and creative reasoning to develop abstract thinking. In carrying out the plan, students can solve the problem according to their strategies they planned in the previous phase. In looking back, the program is very useful to provide students an opportunity to reflect problem-solving process, generalize their solution and create a new in-depth problem. This program was well matched with the dynamic and oscillation Polya#s problem-solving process. Moreover, students can facilitate their motivation to solve a problem with dynamic, multiple representations of the problem and become a powerful problem solve with confidence within an interactive computer environment. As a follow-up study, it is recommended to research the effect of the program in classrooms.

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Long Term Effect of High Glucose and Phosphate Levels on the OPG/RANK/RANKL/TRAIL System in the Progression of Vascular Calcification in rat Aortic Smooth Muscle Cells

  • Kang, Yang Ho;Jin, Jung Sook;Son, Seok Man
    • The Korean Journal of Physiology and Pharmacology
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    • v.19 no.2
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    • pp.111-118
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    • 2015
  • Osteoprotegerin (OPG), receptor activator of NF-${\kappa}B$ ligand (RANKL)/receptor activator of NF-${\kappa}B$ (RANK) axis, and TNF-related apoptosis-inducing ligand (TRAIL) participate in vascular calcification process including atherosclerosis, but their contributions under high glucose (HG) and phosphate (HP) condition for a long-term period (more than 2 weeks) have not been fully determined. In this study, we evaluated the effects of HG and HP levels over 2 or 4 weeks on the progression of vascular calcification in rat vascular smooth muscle cells (VSMCs). Calcium deposition in VSMCs was increased in medium containing HG (30 mmol/L D-glucose) with ${\beta}$-glycerophosphate (${\beta}$-GP, 12 mmol/L) after 2 weeks and increased further after 4 weeks. OPG mRNA and protein expressions were unchanged in HG group with or without ${\beta}$-GP after 2 weeks. However, after 4 weeks, OPG mRNA and protein expressions were significantly lower in HG group with ${\beta}$-GP. No significant expression changes were observed in RANKL, RANK, or TRAIL during the experiment. After 4 weeks of treatment in HG group containing ${\beta}$-GP and rhBMP-7, an inhibitor of vascular calcification, OPG expressions were maintained. Furthermore, mRNA expression of alkaline phosphatase (ALP), a marker of vascular mineralization, was lower in the presence of rhBMP-7. These results suggest that low OPG levels after long term HG and phosphate stimulation might reduce the binding of OPG to RANKL and TRAIL, and these changes could increase osteo-inductive VSMC differentiation, especially vascular mineralization reflected by increased ALP activity during vascular calcification.

Cytotoxic Evaluation of Plant Essential Oils in Human Skin and Lung Cells

  • Ahn, Changhwan;Park, Mi-Jin;Kim, Jae-Woo;Yang, Jiyoon;Lee, Sung-Suk;Jeung, Eui-Bae
    • Journal of the Korean Wood Science and Technology
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    • v.46 no.2
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    • pp.166-177
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    • 2018
  • Plant essential oils are defined as fragrant volatile oils extracted from leaves, stems, fruits, flowers, and roots of a plant. Such oils are composed of multiple components and multiple functions. By accumulation of inductive information, various plant essential oils have been studied for using in therapeutic medicine for various diseases. Despite of the apparent advantages of essential oils as a source of therapeutic medicines, plant essential oils have many limitations, including cytotoxic side effects. Therefore, it is necessary to evaluate the toxicity and the mechanisms of cytotoxicity of such oils. In this study, we evaluated the cytotoxicity to human-derived cell lines of 10 plant essential oils provided by National Institute of Forest Science (i.e., Larix kaempferi; Abies holophylla; Zanthoxylum ailanthoides; Pinus parviflora; Tsuga sieboldti; Chamaecyparis pisifera; Cryptomeria japonica; Pinus densiflora; Illicium anisatum; Pinus thunbergii). Cytotoxicity evaluations were accomplished by using CCK-assays and PCR-based cytotoxicity-related marker gene analyses with A549 cell line, and the Detroit551 cell line which are lung and skin cell line. The genes were analyzed included caspase-3 has a role in cell apoptosis, and the other cyclinA, cyclinB, cyclinD, and cyclinE regulated cell cycling for the cell proliferation. By examining the five cytotoxicity-related marker genes by performing real-time PCR and examined the cytostatic gene regulation associated with the various essential oils. The results of this study showed that the degree of cytotoxicity and the cytostatic gene regulation which could give precious information for using the plant essential oil for the clinical usages.

Acid Property and Catalytic Activity on Mordenites Treated by Hydrochloric Acid and Hydrofluoric Acid (염산 및 불산처리 모더나이트의 산특성과 촉매활성)

  • Han, Young-Taek;Ha, Baik-Hyon
    • Applied Chemistry for Engineering
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    • v.2 no.1
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    • pp.77-85
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    • 1991
  • A series of samples having different $SiO_2/Al_2O_3$ ratio were prepared by treating hydrogen mordenites with boiling hydrochloric acid and with hydrofluoric acid. The acidities of these samples were measured by TPD of $NH_3$ and by pyridine adsorption using IR, and the catalytic activities and selectivities of isomerization were measured for the reaction of ortho-xylene. For the samples treated by boiling hydrochloric acid, the acidities decreased with the increasing $SiO_2/Al_2O_3$ ratio caused by the extraction of framework aluminum. The sample having the $SiO_2/Al_2O_3$ ratio or 22 showed better activity than the others. For the samples treated by hydrofluoric acid, the content of chemically binding fluorine increased with the increasing contact time of hydrofluoric acid solution. The catalytic activities decreased with the hydrofluoric acid treatment due to the decreased acid sites resulted from the extraction of aluminum and silicon as well as the hydroxyl group replacement by the fluoride ion. The slightly increasing catalytic activities, however, came from the newly created acid sites, due to the removal of surface silicon, having enhanced by the inductive effect of binding fluorin with further acid treatment.

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Inductive Effect of Scutellariae radix on Glutathione S-Transferase Yc1/2 from Rat Liver (황금이 백서의 간 조직 글루타치온 에스-전이 효고 Ycl/2의 발현 효과)

  • Kim Young Sook;Kim Dong Hyun;Choi Mi Jung;Kim Sung Min;Park Rae Kil;Kwon Kang Beom;Ryu Do Gon;Kim Bok Ryang
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.6
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    • pp.1448-1452
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    • 2003
  • The water extract of Scutellariae radix was treated to rat and the primary culture of hepatocytes, and the expressions of several glutathione S-transferase (GST) isozymes and the activity of GST Yc1/2 were investigated by Western blot and by the use of HPLC. The results were obtained as follows: The water extract of Scutellariae radix did not induce the expressions of cytosolic GST Ya and GST Yp in rat livers. But, the extract increased the expression of cytosolic GST Yc1/2 to 2-4 fold higher than control. The expression of GST Yc1/2 in the primary culture of rat hepatocytes was induced by the water extract of Scutellariae radix in a dose-dependent manner, reaching 21-fold over control with 50 ㎍/㎖ treatment. The induction of the expression of GST Yc1/2 in rat livers increased the formation of AFB₁-glutathione conjugate from AFB₁-8,9-epoxide which was made in the metabolism of AFB₁.

Fabrication and Small scale Short Circuit Tests of Hybrid Fault Current Limiter Employing Asymmetric Non-Inductive Coil and Fast Switch (이종초전도 코일을 이용한 하이브리드형 한류기의 제작 및 단락실험)

  • Jang, Jae-Young;Kim, Young-Jae;Na, Jin-Bae;Choi, Suk-Jin;Lee, Woo-Seung;Lee, Chang-Young;Park, Dong-Keun;Ko, Tae-Kuk
    • Progress in Superconductivity and Cryogenics
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    • v.13 no.1
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    • pp.41-45
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    • 2011
  • Hybrid fault current limiters (FCL) have been researched at Yonsei University. The hybrid FCL has advantages such as having a rapid response to a sudden fault situation and a fast recovery time from a quench. It consists of an asymmetric HTS coil, a switching module, and a bypass reactor. The asymmetric HTS coil is wound with two different types of HTS wires in an opposite direction so that it has nearly zero inductance at the superconducting state. When the quench occurs at the fault state, a strong magnetic field is generated from the asymmetric coil because of different quench characteristics of two HTS wires, and then a repulsive force is induced in the switching module. The force opens the switch and the fault current is pushed into the bypass reactor. In this research, we analyzed the cause of the repulsive force and confirmed, experimentally and computationally, that the magnitude of a repulsive force is varied by changing the gap distance between the asymmetric coil and the switching module. By using the FEM simulation, we calculated the repulsive force with respect to the gap distance and verified that the effect of the gap distance. Then, short circuit test was carried out to confirm the correct operation of the fast switch.