• Title/Summary/Keyword: Indion 190 resin

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Practical and Green Approach for N-Boc Protection of Amines Catalyzed by Indion 190 Resin (Indion 190 수지에 의한 아민촉매의 N-Boc protection의 실용적이며 친환경적 접근법)

  • Chaskar, Atul;Yewale, Sampat;Langi, Bhushan;Deokar, Hrushikesh
    • Journal of the Korean Chemical Society
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    • v.53 no.4
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    • pp.422-426
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    • 2009
  • An efficient, chemoselective and practical protocol for N-Boc protection of amines using di-tertbutoxypyrocarbonate $(Boc)_{2}O$ in presence of Indion 190 resin. Resin was easily separated from the reaction mixture by filtration and reused in subsequent reactions without any apparent loss of activity. Simple workup, mild condition, short reaction time and high yield are some of the striking features of the present process.