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Alterations of Glutathione and Glutathione-Dependent Enzyme Activities by Monosodium-L-Glutamate in Rats with Carbon Tetrachloride-Induced Liver Damage (사염화탄소와 Monosodium-L-Glutamate 병용투여에 의한 간조직의 환원형글루타치온 함량 및 그의 관련효소활성의 변화)

  • 김형춘;이왕섭;전완주;김수희;주왕기
    • YAKHAK HOEJI
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    • v.35 no.5
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    • pp.384-388
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    • 1991
  • To explore the effect of monosodium-L-glutamate(MSG) on CCI$_{4}$-damaged liver in Wister male rat, 5% MSG solution as drink water were administered after S.C. injection of 0.1 mg/kg CC1$_{4}$ twice a week for 4 weeks. After last administration of MSG, heptic glutathione(GSH) dependent system was assayed. It showed that MSG increased significanly hepatic glutathione(GSH) and glutathione peroxidase(GSH$_{px}$), but decreased glutathione-S-transferase(GST) acivity in normal rats. MSG increased significantly the GSH$_{px}$ and GST activities in rats with CCI$_{4}$-induced liver damage. These results indicate that decrease of GSH dependent systems in CC1$_{4}$ liver injury might be partially elevated by coadministration of MSG.

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Evolutionary Design of a Fuzzy Logic Controller for Multi-Agent Systems

  • Jeong, Il-Kwon;Lee, Ju-Jang
    • 제어로봇시스템학회:학술대회논문집
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    • 1998.10a
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    • pp.507-512
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    • 1998
  • It is an interesting area in the field of artificial intelligence to and an analytic model of cooperative structure for multi-agent system accomplishing a given task. Usually it is difficult to design controllers for multi-agent systems without a comprehensive knowledge about the system. One of the way to overcome this limitation is to implement an evolutionary approach to design the controllers. This paper introduces the use of a genetic algorithm to discover a fuzzy logic controller with rules that govern emergent co-operative behavior: A modified genetic algorithm was applied to automating the discovery of a fuzzy logic controller jot multi-agents playing a pursuit game. Simulation results indicate that, given the complexity of the problem, an evolutionary approach to and the fuzzy logic controller seems to be promising.

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A Smart Drug/Medicine Pack for u-Medication Monitoring (유비쿼터스 투약 감시를 위한 스마트 투약 팩)

  • Park, Jang-Hwan;Lee, Tae-Soo;Kim, Young-Chol
    • Journal of Institute of Control, Robotics and Systems
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    • v.12 no.1
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    • pp.23-27
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    • 2006
  • As a pervasive healthcare application to help medication of elderly patients, the smart compliance monitors have been recently proposed. In this paper, we present a new smart drug/medicine pack (SDP) for ubiquitous medication monitoring, for which the packaging is either paper packet or blister pack. This ubiquitous compliance monitor is composed of several SDPs and a Bluetooth equipped PDA phone. The SDP is a wireless module that monitors the medication consumption unobtrusively by transmitting the sensed data of 'drug removal' events to the medical center and by reminding patients when they take a dose on their mobile phone. The communication between SDP modules and PDA is realized via Bluetooth. The PDA is basically embedded to indicate the medication record and to alert every prescribed medication time during treatment. Experimental results show that the proposed system works exactly when the SDPs are far within about 2 [m] from PDA.

Statistical Prediction of False Alarm Rates in Automatic Vision Inspection System (자동결함 검출시스템에서 결함크기 측정오차로 인한 오검률의 통계적 예측)

  • Joo, Young-Bok;Huh, Kyung-Moo;Park, Kil-Houm
    • Journal of Institute of Control, Robotics and Systems
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    • v.15 no.9
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    • pp.906-908
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    • 2009
  • AVI (Automatic Vision Inspection) systems automatically detect defect features and measure their sizes via camera vision. It is important to predict the performance of an AVI to meet customer's specification in advance. Also the prediction can indicate the level of current performance of an AVI system. In this paper, we propose a statistical method for prediction of false alarm rate regarding inconsistency of defect size measurement process. For this purpose, only simple experiments are needed to measure the defect sizes for certain number of times. The statistical features from the experiment are utilized in the prediction process. Therefore, the proposed method is swift and easy to implement and use. The experiment shows a close prediction compared to manual inspection results.

STUDY OF SUPERHUMPS IN THE RECENTLY DISCOVERED SU UMA DWARF NOVAE

  • VOLOSHINA, I.;KHRUZINA, T.;METLOV, V.
    • Publications of The Korean Astronomical Society
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    • v.30 no.2
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    • pp.241-245
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    • 2015
  • In this work we present the results of light curve analysis for two cataclysmic variables detected recently in the SDSS project: SDSS J090350.73+330036.1 and J150240.98+333423.9. Photometric observations of the first were obtained during a superoutburst in May 2010. Our observations clearly indicate the presence of superhumps in the light curves, suggesting SDSS J090350.73+330036.1 is an SU UMa dwarf nova. We determined the period of the superhumps. We also carried out fitting using a spiral-arm model in order to determine parameters of the accretion disk, hot line, and other components of this system. Photometric observations of the second, J150240.98+333423.9, were obtained during the post-maximum decline, during April-June 2012. Photometric variability of this system has been studied in an inactive state. We obtained its parameters via a combined model fitted to the observed light curves by ${\chi}^2$ minimization.

Simultaneous identification of stiffness and damping based on derivatives of eigen-parameters

  • Lia, H.;Liu, J.K.;Lu, Z.R.
    • Structural Engineering and Mechanics
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    • v.55 no.4
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    • pp.687-702
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    • 2015
  • A method based on derivatives of eigen-parameters is presented for damage detection in discrete systems with dampers. The damage is simulated by decrease on the stiffness coefficient and increase of the damping coefficient. In the forward analysis, the derivatives of eigen-parameters are derived for the discrete system. In the inverse analysis, a derivative of eigen-parameters based model updating approach is used to identify damages in frequency domain. Two numerical examples are investigated to illustrate efficiency and accuracy of the proposed method. Studies in this paper indicate that the proposed method is efficient and robust for both single and multiple damages and is insensitive to measurement noise. And satisfactory identified results can be obtained from few numbers of iterations.

A Study on Inventory Control Policy for Quantity-Discount and Budget Constraint (수량 할인과 예산 제약을 고려한 재고관리 정책에 관한 연구)

  • Lee, Dongju
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.38 no.2
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    • pp.145-151
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    • 2015
  • As order quantity is increased, the ordering cost per item will be cheaper due to saving of transportation and material handling costs. In this paper, two realistic assumptions such as quantity discount and budget limit are considered. Quantity discount means that all units in the order will be discounted according to the predetermined order levels. Budget limit represents that the costs for inventory investments are bounded. This paper develops a Lagrangian relaxation approach for a continuous review inventory model with a budget constraint and quantity discounts. Computational results indicate that the proposed approach provides a good solution. Sensitivity analysis is done to get some insights on budget limit and quantity discount. As budget limit or the amount of discount according to order quantity is increased, order quantity is increased, whereas reorder point is not always increased.

Discussion on the Indicator System and Methods of Environment Impact Assessment for Port Master Planning

  • Honglei, Xu;Jinxiang, Cheng;Yan, Xie
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2006.10a
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    • pp.213-219
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    • 2006
  • Planning Environment Impact Assessment is regarded as one of the most important measures to achieve sustainable development in China. Conduct environment impact assessment for port planning was prescribed by Environment impact Assessment Law of the People's Republic of China. This Paper introduces the basic concept of Planning Environment Impact Assessment and Port Planning firstly, and then discusses the assessment indicators and assessment methods adopted in the Environment Impact Assessment for port planning. At last, the application of the indicators and methods are illustrated in case studies based on the practice on Port Planning's Environment Assessment in China.

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Evaluation of an Abstract Component Model for Embedded Systems Development

  • Bunse, Christian;Choi, Yunja;Gross, Hans Gerhard
    • Journal of Information Processing Systems
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    • v.8 no.4
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    • pp.539-554
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    • 2012
  • Model-driven and component-oriented development is increasingly being used in the development of embedded systems. When combined, both paradigms provide several advantages, such as higher reuse rates, and improved system quality. Performing model-driven and component-oriented development should be accompanied by a component model and a method that prescribes how the component model is used. This article provides an overview on the MARMOT method, which consists of an abstract component model and a methodology for the development of embedded systems. The paper describes a feasibility study that demonstrates MARMOT's capability to alleviate system design, verification, implementation, and reuse. Results indicate that model-driven and component-based development following the MARMOT method outperforms Agile development for embedded systems, leads to maintainable systems, and higher than normal reuse rates.

Properties of $\beta$-1,3-glucan Synthase System in Saccharomyces cerevisiae (Saccharomyces cerevisiae의 베타-1,3-글루칸 합성효소 체계의 특성)

  • Park, Hee-Moon;Kim, Jeong-Yoon;Kim, Sung-Uk;Bok, Song-Hae
    • Microbiology and Biotechnology Letters
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    • v.23 no.3
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    • pp.316-321
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    • 1995
  • Some properties of $\beta$-1, 3-glucan synthase system in Saccharamyces cerevisiae were investigated. By extraction with detergent and salt, the membrane preparations could be dissociated into two components, one soluble, the other still membrane bound. Both components, in addition to GTP, were necessary for the activity of $\beta$-1, 3-glucan synthase like other fungi. The protective effect of guanosine nucleotides on the soluble factor pointed to the possibility that this fraction contained a GTP-binding protein. Addition of increasing amounts of soluble factor to a constant amount of insoluble catalytic factor, vice versa, gave rise to a saturation curve. These results, including different types of evidence, indicate that the soluble factor and the catalytic factor form a complex.

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