• Advances in nano research
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• v.15 no.6
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• pp.551-565
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• 2023

Coupled porous curved beams, due to their low weight and high flexibility, have many applications in engineering. This study investigates the vibration behavior of coupled porous curved beams in different boundary conditions. The system consists of two curved beams connected by a mid-layer of elastic springs. These beams are made of various materials, such as homogenous steel foam, and composite materials with PMMA (polymethyl methacrylate) and SWCNT (single-walled carbon nanotube) used as the matrix and nanofillers, respectively. To obtain equivalent material properties, the role of mixture (RoM) was employed, followed by the implementation of the porosity function. The system's governing equations were obtained by employing FSDT and Hamilton's law. To investigate thermal vibration, temperature was implemented as a load in the governing equations. The GDQ method was used to solve these equations. To demonstrate the applicability of the GDQ method in calculating the frequencies of the system and the correctness of the developed program, a validation study was conducted. After validation, numerous examples were presented to investigate the behavior of single and coupled curved beams in various material properties and boundary conditions. The results indicate that the frequencies of the curved beams and the system depend highly on the amount of porosity (n) and the distribution pattern. The system frequencies decreased with an increase in the porosity coefficient. The stiffness of the springs had no effect on the first mode frequency but increased frequencies of other modes in a specific range. The frequencies of the system decreased with an increase in environmental temperature.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.10
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• pp.2701-2717
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• 2023

In this paper, a hybrid fuzzy-based method is suggested for determining India's best system for power generation. This suggested approach was created using a fuzzy-based combination of the Giza Pyramids Construction (GPC) and Recalling-Enhanced Recurrent Neural Network (RERNN). GPC is a meta-heuristic algorithm that deals with solutions for many groups of problems, whereas RERNN has selective memory properties. The evaluation of the current load requirements and production profile information system is the main objective of the suggested method. The Central Electricity Authority database, the Indian National Load Dispatch Centre, regional load dispatching centers, and annual reports of India were some of the sources used to compile the data regarding profiles of electricity loads, capacity factors, power plant generation, and transmission limits. The RERNN approach makes advantage of the ability to analyze the ideal power generation from energy data, however the optimization of RERNN factor necessitates the employment of a GPC technique. The proposed method was tested using MATLAB, and the findings indicate that it is effective in terms of accuracy, feasibility, and computing efficiency. The suggested hybrid system outperformed conventional models, achieving the top result of 93% accuracy with a shorter computation time of 6814 seconds.

• Nuclear Engineering and Technology
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• v.55 no.12
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• pp.4518-4526
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• 2023

NECP-SARAX is a neutronics analysis code system for advanced reactor developed by Nuclear Engineering Computational Physics Laboratory of Xi'an Jiaotong University. In past few years, improvements have been implemented in TULIP code which is the cross-section generation module of NECP-SARAX, including the treatment of resonance interface, considering the self-shielding effect in non-resonance energy range, hyperfine group method and nuclear library with thermal scattering law. Previous studies show that NECP-SARAX has high performance in both fast and thermal spectrum system analysis. The accuracy of TULIP code in fast and thermal spectrum system analysis is demonstrated preliminarily. However, a systematic verification and validation is still necessary. In order to validate the applicability of TULIP code for full energy range, 147 fast spectrum critical experiment benchmarks and 170 thermal spectrum critical experiment benchmarks were selected from ICSBEP and used for analysis. The keff bias between TULIP code and reference value is less than 300 pcm for all fast spectrum benchmarks. And that bias keeps within 200 pcm for thermal spectrum benchmarks with neutron-moderating materials such as polyethylene, beryllium oxide, etc. The numerical results indicate that TULIP code has good performance for the analysis of fast and thermal spectrum system.

• BMB Reports
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• v.32 no.3
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• pp.311-316
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• 1999

Studies in adipocytes indicate that secretion of active lipoprotein lipase (LPL) was strictly regulated by a quality control system in the endoplasmic reticulum (ER). However, there has been no report about the ER chaperones participating in the folding and assembly of LPL. Many chaperones are known to bind unfolded proteins and dissociate from them through the ATP-hydrolyzing reaction. In this study, putative ER chaperones for LPL were determined by affinity chromatography using denatured LPL as an affinity ligand and elution with ATP. BiP, grp94, calreticulin, and another 50 kDa K-D-E-L protein in the ER of rat adipose tissue were bound to denatured LPL and eluted by ATP. Calnexin was bound to denatured LPL; however, it was not eluted by ATP but by acetic acid. These results indicate that, at least, BiP, grp94, calreticulin, calnexin, and the unidentified 50 kDa protein might act as putative chaperones for the proper folding and assembly of LPL in ER.

• BMB Reports
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• v.38 no.2
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• pp.211-217
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• 2005

Cordyceps, an entomopathogenic fungus, contains many health-promoting ingredients. Recent reports indicate that the consumption of cordyceps helps reduce blood-sugar content in diabetics. However, the mechanism underlying this reduction in circulatory sugar content is not fully understood. Methanolic extracts were prepared from the fruiting bodies of Paecilomyces tenuipes, and 4-beta acetoxyscirpendiol (4-ASD) was eventually isolated and purified. $Na^+$/Glucose transporter-1 (SGLT-1) was expressed in Xenopus oocytes, and the effect of 4-ASD on SGLT-1 was analyzed utilizing a voltage clamp and by performing 2-deoxy-D-glucose (2-DOG) uptake studies. 4-ASD was shown to significantly inhibit SGLT-1 activity compared to the non-treated control in a dose-dependent manner. In the presence of the derivatives of 4-ASD (diacetoxyscirpenol or 15-acetoxyscirpendiol), SGLT-1 activity was greatly inhibited in an 4-ASD-like manner. Of these derivatives, 15-acetoxyscirepenol inhibited SGLT-1 as well as 4-ASD, whereas diacetoxyscirpenol was slightly less effective. Taken together, these results strongly indicate that 4-ASD in P. tenuipes may lower blood sugar levels in the circulatory system. We conclude that 4-ASD and its derivatives are effective SGLT-1 inhibitors.

• 한국신재생에너지학회:학술대회논문집
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• 2008.05a
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• pp.349-352
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• 2008

This study has numerically modeled the combustion processes of the turbulent swirling premixed lifted syngas flames in the low-swirl burner (LSB). In these turbulent swirling premixed flames, the four tangentially-injected air jets induce the turbulent swirling flow which plays the crucial role of stabilizing the turbulent lifted flames. In the present approach, the turbulence-chemistry interaction is represented by the level-set based flamelet model. Numerical results indicate clearly that the present level-set based flamelet approach has realistically simulated the structure and stabilization mechanism of the turbulent swirling premixed lifted flames in the low-swirl burner. Computations are made for the wide range of the syngas chemical composition and the dilution level at two pressure conditions (1.0, 5.0 bar). Numerical results indicate that the lifted height in the LSB is increased by decreasing the H2 percentage and increasing the dilution level at the given equivalence ratio. It is also found that the flashback is occurred for the hydrogen composition higher than 80% at the equivalence ratio, 0.8. However, at the syngas composition range in the IGCC system, the stable lean-premixed lifted flames are formed at the low-swirl burner.

• The Korea Journal of Herbology
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• v.25 no.3
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• pp.19-25
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• 2010

Objective : The aim of this study was to investigate anti-inflammatory activity of SD-01 methanol extract in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. Methods : Cytotoxic activity of SD-01 methanol extract on RAW 264.7 cells was measured using 5-(3-caroboxymeth-oxyphenyl)-2H-tetra-zolium inner salt (MTS) assay. The nitric oxide (NO) production was measured by Griess reagent system. And proinflammatory cytokines and $PGE_2$ were measured by ELISA method. The levels of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), $I{\kappa}$-B-alpha and nuclear NF-${\kappa}$ B p65 expression were detected by western blot. Results : Our results indicated that methanol extract of SD-01 significantly inhibited the LPS-induced NO, $PGE_2$ production and iNOS, COX-2 expression accompanied by an attenuation of TNF-$\alpha$, IL-$1\beta$, IL-6 and MCP-1 production in RAW 264.7 cells. Moreover, methanol extract of SD-01 treatment also blocked LPS-induced NF-kB activation. Conclusion : These findings indicate that methanol extract of SD-01 inhibits the production of pro-inflammatory mediators and cytokines via suppression of NF-${\kappa}$ B activation. Take together, these results indicate that methanol extract of SD-01 has the potential for use as an agent of anti-chronic inflammatory diseases.

• Economic and Environmental Geology
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• v.32 no.3
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• pp.237-245
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• 1999

The Mujeong au-Ag hydrothermal vein type deposits occur within the Teriary igneous rocks of the Janggi basin. Ore minerals consist of pyrite, pyrrhotite, sphalertite, chalcopyrite, galena, cosalite, lillianite, argentite and electrum, and associated with epidotization, sericitization and pyritization. Fluid inclusion studies reveal that ore fluids were low saline with a simple NaCl-$H_{2}O$ system. Fluid inclusion data indicate that homogenization temperatures and salinities of fluid are 150 to $340^{\circ}C$ and 1.0 to 6.5wt.% NaCl equivalent, respectively. Sulfur isotope compositions of sulfied minerals ( ${\delta}^{34}S$=6.2 to 9.6$\textperthousand$) indicate that the ${\delta}^{34}S_{H2S}$ value of ore fluids was about 10.4$\textperthousand$. This ${\delta}^{34}S_{H2S}$ value is likely consistent with and hydrothermal sulfur, whereas the fluids were highly influenced by mixing with meteoric water. Measured and calculated oxygen and hydrogen isotope values (${\delta}^{18}O_{H2O}$=-2.7 to 3.4 $\textperthousand$, ${\delta}D_{H2O}$ = -83.6 to -52.7 $\textperthousand$) of ore forming fluids suggest mixing with hydrothermal and meteoric water. Equilibrium thermodynamic interpretation by mineral assemblages and chemistry indicates that sulfur fugacities (-log $fs_2$) ore forming fluids range from 9.0 to 12.6 atm stage II.

• Journal of Labour Economics
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• v.24 no.3
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• pp.39-62
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• 2001

The purpose of this paper is to investigate determinants of firms' workforce reduction ratio in Korea, utilizing a dataset surveyed by Korea Labor Institute in 1999. We hypothesize that firms' employment structure has an effect on their workforce reduction ratio. Our findings indicate that the ratio of the layoffs and/or the buyouts is higher, as the average tenure of employees is longer. The findings also indicate that the unionization as a proxy variable for the intensity of the seniority-based pay moderates positively the effect of employees' tenure on the workforce reduction ratio, implying that the more seniority-based the pay system is, the higher positive effect the average tenure of employees has on the workforce reduction ratio.

• Geomechanics and Engineering
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• v.16 no.1
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• pp.49-58
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• 2018

Open-mode cracks could be commonly observed in layered rocks. A concept model is firstly used to explore the mechanism of the vertical cracks (VCs) in the top layer. Then the crack behaviour of the two-layer model is simulated based on a cohesive zone model (CZM) for layer interfaces and a plastic-damage model for rocks. The model indicates that the tensile stress normal to the VCs changes to compression if the crack spacing to layer thickness ratio is lower than a threshold. The results indicate that there is a threshold for interfacial shear strength that controls the crack patterns of the layered system. If the shear strength is lower than the threshold, the top layer is meshed by the VCs and interfacial cracks (ICs). When the shear strength is higher than the threshold, the top layer is meshed by the VCs and parallel cracks (PCs). If the shear strength is comparative to the threshold, a combining pattern of VCs, PCs and ICs for the top layer can be formed. The evolutions of stress distribution in the crack-bound block indicate that the ICs and PCs can reduce the load transferred for the substrate layer, and thus leads to a crack saturation state.