• 대한기계학회논문집B
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• 제25권1호
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• pp.18-28
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• 2001

The present study investigates flow dynamics between two dimensional compliant plates under sinusoidal flow conditions in order to understand influence of wall motion, impedance phase angle (time delay between pressure and flow waveforms), and non-Newtonian fluid on wall shear stress using computational fluid dynamics. The results showed that wall motion induced additional terms in the streamwise velocity profile and the pressure gradient. These additional terms due to wall motion reduced the amplitude of wall shear stress and also changed the mean wall shear stress. The trend of the changes was very different depending on the impedance phase angle. As the impedance phase angle was changed to more negative values, the mean wall shear stress decreased while the amplitude of wall shear stress increased. As the phase angle was reduced from 0°to -90°under $\pm$4% wall motion, the mean wall shear stress decreased by 12% and the amplitude of wall shear stress increased by 9%. Therefore, for hypertensive patients who have large negative phase angles, the ratio of amplitude and mean of the wall shear stress is raised resulting in a more vulnerable state to atherosclerosis according to the low and oscillatory shear stress theory. We also found that non-Newtonian characteristics of the blood protect atherosclerosis by decreasing the oscillatory shear index.

• 대한한방내과학회지
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• 제38권4호
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• pp.531-540
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• 2017

Objectives: This study discusses the effects of constitution therapy on adolescent ulcerative colitis. Methods: A 12-year-old male patient was treated with western medication for six months and herbal medicine for one year and six years; however, his abdominal pain, mucousy stool, bloody stool, and diarrhea persisted. He was diagnosed as having Taeumin according to Sasang constitution classification and treated with Sasang constitutional medicine (i.e., Yeuldahanso-tang and food restrictions based on constitutional medicine theory). Before the first treatment, his Pediatric Ulcerative Colitis Activity Index (PUCAI) score was 35, but this score decreased to 15 within six months and was maintained at 10 by 18 months of treatment. He took the herbal medication for 38 months, and his PUCAI score was 0 at the end of treatment. His liver functioned normally despite long-term drug use, and a follow-up colonoscopy showed no ulcerative colitis except melanosis, which was presumed to be caused by the herbal medicine. Ulcerative colitis in pediatric adolescents requires treatment with pharmacotherapy and dietary control based on constitutional medicine to maintain disease remission. Conclusions: Constitutional therapy is effective for treating adolescent ulcerative colitis. More clinical data are needed for patients with ulcerative colitis.

• Structural Engineering and Mechanics
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• 제22권6호
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• pp.665-683
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• 2006

The strength behaviors of Fiber Reinforced Plastics (FRP) Composites can be greatly influenced by the properties of constitutive materials, the laminate structures, and load conditions etc, accompanied by many uncertainty factors. So the reliability study on FRP is an important subject of research. Many achievements have been made in reliability studies based on the probability theory, but little has been done on the roles played by fuzzy variables. In this paper, a fuzzy reliability model for FRP laminates is established first, in which the loads are considered as random variables and the strengths as fuzzy variables. Then a numerical model is developed to assess the fuzzy reliability. The Monte Carlo simulation method is utilized to compute the reliability of laminas under the maximum stress criterion. In the second part of this paper, a generalized fuzzy reliability model (GFRM) is proposed. By virtue of the fact that there may exist a series of states between the failure state and the function state, a fuzzy assumption for the structure state together with the probabilistic assumption for strength parameters is adopted to construct the GFRM of composite materials. By defining a generalized limit state function, the problem is converted to the conventional reliability formula that enables the first-order reliability method (FORM) applicable in calculating the reliability index. Several examples are worked out to show the validity of the models and the efficiency of the methods proposed in this paper. The parameter sensitivity analysis shows that some of the mean values of the strength parameters have great influence on the laminated composites' reliability. The differences resulting from the application of different failure criteria and different fuzzy assumptions are also discussed. It is concluded that the GFRM is feasible to use, and can provide an effective and synthetic method to evaluate the reliability of a system with different types of uncertainty factors.

• 응용통계연구
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• 제17권3호
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• pp.573-594
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• 2004

최근 국내에서 통계학 전공자들뿐만 아니라 일반인들도 읽을 수 있는 통계학 책이 많이 출판되는 현상은 대단히 반가운 일이다. 그 책들 가운데에는 국내 저자가 쓴 것보다는 번역서가 더 많은데, 번역도서의 양적인 팽창은 한편으로 그 책들이 번역되어야할 이유가 과연 무엇인가라는 질문을 비롯해서 번역의 질적인 면을 검토할 필요성도 제기한다. 이 글에서는 지난 2003년에 나온 번역서 네 권을 대상으로 그 책들에 담긴 색인과 참고문헌, 통계학 이론과 통계학 용어, 그리고 통계학의 역사에 대해 중점적으로 살펴보았다. 또한 그 책들을 소개하는 일간신문의 신간소개나 서평 기사들도 검토하였다. 결론적으로 이 글의 진단은 번역서들에서 보게 되는 많은 문제점들이 통계학과 거리가 먼 번역자들이 그 책을 옮겼기 때문에 생긴다는 것이다. 따라서 국내의 통계학 전문가들이 일반 대중을 위한 통계학 책의 필요성, 번역 작업이 갖는 의미, 번역할 책의 선택에 대해 좀더 활발하게 토론하고 무엇보다 직접 번역 작업에 참여할 필요가 있겠고, 나아가 일반 한국 사람을 대상으로 한국어로 된 훌륭한 통계학 책을 쓰는 작업에도 더 적극적일 필요가 있겠다.

• 한국펄프종이공학회:학술대회논문집
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• 한국펄프종이공학회 2006년도 PAN PACIFIC CONFERENCE vol.1
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• pp.31-36
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• 2006

Tritium has been used to directly measure the exchangeable hydrogen in bleached softwood kraft pulp. The hydrogen atoms associated with hydroxyl groups in pulp or with water contained in the pulp can dissociate and exchange with the hydrogen atoms in bulk water. Tritium is a radioactive isotope of hydrogen and behaves almost identically to it. The distribution of tritium between pulp and water ($k_{pw}$) can be easily measured and becomes an index of the protons available fur hydrogen bonding. Bleached kraft pulp was refined in a PFI mill to a range of freenesses. Tritiated water was added and the amount exchanged measured. There was a slight steady increase in $k_{pw}$ until approximately 300 CSF; $k_{pw}$ then rose sharply between 300 CSF and 100 CSF. This rise appears to correlate with FSP. It is likely that the action of refining on the fiber reaches a threshold at about 300 CSF causing the fiber surface to break open creating exponentially more surface area. This theory is visually confirmed through light microscopy. The slow increase in fibrillation of the fibers above 300 CSF correlates with the increase in $k_{pw}$. Beyond the threshold of 300 CSF a dramatic difference in fibrillation is shown, also corresponding with the large increase in $k_{pw}$. The freeness difference around 300 CSF is small, but the change in fiber properties is extreme within this region. This change in properties could lead to sheet breaks and other disruptions when producing products around the threshold. This study leads to a better understanding of how fiber changes during refining, resulting in a practical benefit of target freeness determination. Presently, freeness is selected based on product quality and on some measure of runnability. Yet, there are other considerations, demonstrated by the extreme change in fiber properties around 300 CSF.

• 한국지반공학회논문집
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• 제21권6호
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• pp.5-18
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• 2005

본 연구에서는 배수면으로부터의 거리에 따라 점진적으로 진행되는 압밀이 차후의 압밀 거동에 미치는 영향에 대하여 고찰하였다. 이를 위해 압밀진행에 따른 위치 별 투수계수 및 부피압축계수의 변화를 고려할 수 있는 유한차분 압밀해석기법 및 프로그램을 개발하였다. 개발된 해석 프로그램을 이용하여 간극비 변화에 따른 투수계수와 부피압축 켸수의 변화 정도가 다른 다양한 특성의 지반에 대하여 연직배수재가 설치된 모형지반의 압밀거동을 분석하였다. 또한 실제 지반조건에서의 영향 정도를 살펴보기 위하여, 낙동강 하구의 정규압밀 점성토 및 재성형 카올리나이트의 지반 특성을 근간으로 입력치를 결정, 해석을 수행하여 위치 별 점진적 압밀에 의한 영향을 분석하였다. 해석 결과 점진적 압밀 진행에 따른 압밀 지체가 현장의 압밀 거동 이해에 매우 중요하며, 또한 압밀 초기에, 소성성이 크고, 재하하중이 클수록 현저하게 나타남을 알 수 있었다.

• 대한한의학회지
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• 제32권1호
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• pp.56-66
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• 2011

Background: This was a study to analyze Sanghanron through network theory, as the first attempt to construct network models for systems biomedicine in traditional Korean medicine. For this purpose, we investigated the network structure with priority given to two-node connections between symptoms and herbs of Taeyangbyung compilation in Sanghanron. Purpose: We had three goals in carrying out this study. First, to establish the minimum clinical grouping data sets for symptoms and herbs of Taeyangbyung compilation in Sanghanron. Second, to make index files for the obtained data sets. Third, to generate a network structure for systems biomedicine in this part, and analyze its relationship. Methods: Using MS office Excel and Netminer software, we constructed the minimum clinical grouping data sets and the network for systems biomedicine about symptoms and herbs of Taeyangbyung compilation in Sanghanron, and analyzed its relationship. Results: We established the minimum clinical grouping data sets for symptoms and herbs of Taeyangbyung compilation in Sanghanron, using MS Excel. We constructed a network to structurize our database through two-node connections of Netminer program, and analyzed its relationships. Conclusions: Further research on network model for systems biomedicine between symptoms and herbs for three Yang and three Um(Taeyang, Soyang, Yangmyung, Taeum, Soum, Gualum) disease compilation is necessary.

• Asian Pacific Journal of Cancer Prevention
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• 제15권24호
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• pp.10683-10690
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• 2015

The big gap between efficacy of population level prevention and expectations due to heterogeneity and complexity of cancer etiologic factors calls for selective yet personalized interventions based on effective risk assessment. This paper documents our research protocol aimed at refining and validating a two-stage and web-based cancer risk assessment tool, from a tentative one in use by an ongoing project, capable of identifying individuals at elevated risk for one or more types of the 80% leading cancers in rural China with adequate sensitivity and specificity and featuring low cost, easy application and cultural and technical sensitivity for farmers and village doctors. The protocol adopted a modified population-based case control design using 72, 000 non-patients as controls, 2, 200 cancer patients as cases, and another 600 patients as cases for external validation. Factors taken into account comprised 8 domains including diet and nutrition, risk behaviors, family history, precancerous diseases, related medical procedures, exposure to environment hazards, mood and feelings, physical activities and anthropologic and biologic factors. Modeling stresses explored various methodologies like empirical analysis, logistic regression, neuro-network analysis, decision theory and both internal and external validation using concordance statistics, predictive values, etc..

• 한국정보과학회논문지:시스템및이론
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• 제36권6호
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• pp.521-531
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• 2009

플래시 메모리는 하드디스크와 다른 물리적 특성을 가진다. 대표적으로 읽기연산과 쓰기연산의 비용이 다르고, 덮어쓰기(overwrite)가 불가능하여 소거연산(erase)이 선행되어야 한다. 이러한 물리적 제약을 소프트웨어적으로 보완해주기 위해서, 플래시 메모리를 사용하는 시스템은 대부분 플래시 변환 계층(Flash Translation Layer)을 사용한다. 현재까지 효율적인 FTL 기법들이 제안되었으며, 이들은 임의쓰기(random writes) 패턴보다 순차쓰기(sequential writes) 패턴에 훨씬 더 효율적으로 동작한단. 본 논문에서는 플래시 메모리 상에서 B-트리 인덱스를 효율적으로 생성, 유지하기 위한 새로운 기법을 제안한다. B-트리에 키의 삽입, 삭제, 수정 등치 연산을 수행하면 FTL에 비효율적인 임의쓰기 패턴을 많이 발생시키며, 결국 B-트리 인덱스 유지 비용이 커지게 된다. 제안하는 기법에서는 B-트리에서 발생되는 임의쓰기 패턴을 먼저 플래시 메모리의 쓰기 버퍼에 추가쓰기(append writes) 패턴으로 변환하여 저장하고, 추후 이를 FTL에 효율적인 순차쓰기 패턴으로 FTL에 전달한다. 다양한 실험을 통해 제안하는 기법이 기존의 기법보다 플래시 메모리 I/O 비용 측면에서 우수하다는 것을 보인다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2011년도 제41회 하계 정기 학술대회 초록집
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• pp.225-225
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• 2011

The dielectric and optical properties of GaInZnO (GIZO), HfInZnO (HIZO) and InZnO (IZO) thin films on glass by RF magnetron sputtering method were investiged using reflection electron energy loss spectroscopy (REELS). The band gap was estimated from the onset values of REELS spectra. The band gaps of GIZO, HIZO and IZO thin films are 3.1 eV, 3.5 eV and 3.0 eV, respectively, Hf and Ga incorporated into IZO results in an increase in the energy band gap of IZO by 0.5 eV and 0.1 eV. The dielectric functions were determined by comparing the effective cross section determined from experimental REELS with a rigorous model calculation based on the dielectric response theory, using available software package, good agreement between the experimental and fitting results gives confidence in the accuracy of the determined dielectric function. The main peak of Energy Loss Function (ELF) obtained from IZO shows at 18.42 eV, which shifted to 19.43 eV and 18.15 eV for GIZO and HIZO respectively, because indicates the corporation of cation Ga and Hf in the composition. The optical properties represented by the dielectric function e, the refractive index n, the extinction coefficient k, and the transmission coefficient, T of HIZO and IZO thin films were determined from a quantitative analysis of REELS. The transmission coefficient was increased to 93% and decreased to 87% in the visible region with the incorporation of Hf and Ga in the IZO compound.