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Effect of Korean Medicine Treatment Including Korean Medicine Counselling on Weight Loss in Patients with Morbid Obesity: A Retrospective Chart Review (고도비만 환자 대상 한의 비만 상담을 포함한 한의치료의 체중 감량 효과: 후향적 차트 리뷰)

  • Kim, Sungha;Han, Kyungsun;Kwon, Ojin;Lee, Wongu;Yoon, Chulsang;Lee, Jun-Hwan
    • Journal of Korean Medicine for Obesity Research
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    • v.21 no.1
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    • pp.22-31
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    • 2021
  • Objectives: We conducted a retrospective chart review to investigate the effects of Korean Medicine (KM) treatment on weight loss in patients with morbid obesity (body mass index [BMI]≥30 kg/m2) and to compare the effects of KM counseling and non-counseling on weight loss. Methods: We performed a retrospective chart review of patients with morbid obesity who received KM treatment for at least 1 month. We evaluated the effects of KM treatment on body weight, BMI, body fat, fat mass, EuroQol-5D, and the Korean version of the obesity-related quality of life scale (KOQOL). We also assessed the liver and kidney functions, and adverse events. We performed a comparative analysis between the counseling and non-counseling groups. Results: A total of 37 patients who underwent 4 weeks of KM treatment involving Wolbi-tang, electroacupuncture, and KM counseling were included in this study. Twenty-one patients were assigned to the counseling group and sixteen patients to the non-counseling group. There was a significant decrease in weight, BMI, fat mass, and KOQOL (P<0.05) with improvements in total cholesterol, low-density lipoprotein, and triglycerides. The counseling group had a greater reduction in body weight, BMI, body fat, and fat mass compared to the non-counseling group, although it was not significant. In the BMI below 35 (n=25), the reduction ratio of body weight, body fat mass, and body fat was higher in the counseling group than in the non-counseling group; additionally, body fat decreased significantly in counseling group (P<0.05). No severe adverse effects were observed. Conclusion: KM treatment could be effective for weight loss, especially in patients with morbid obesity, KM counseling could also be a good tool for weight loss, typically in patients with BMI<35 kg/m2.

The Effect of Second-Generation Antipsychotics Administration for 1-Year on the Platelet Activities in Patients With Schizophrenia: Retrospective Study (조현병 환자에서 1년간의 2세대 항정신병약물 지속적 투여가 혈소판 활성도에 미치는 영향: 후향적 연구)

  • Yoon-Seok, Oh;Jong Wook, Lee;Hong-Seok, Oh;Seung-Jun, Kim;Na-Hyun, Lee;Woo Young, Im;Ji-Woong, Kim
    • Korean Journal of Psychosomatic Medicine
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    • v.30 no.2
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    • pp.165-171
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    • 2022
  • Objectives : This study was conducted to investigate the effect of 1-year administration of second-generation antipsychotics (SGAs) on the platelet activity in patients with schizophrenia through a retrospective review of the medical records. Methods : The mean platelet component (MPC) value was used as an index of the platelet activity. The included subjects (N=24) were the patients who were confirmed to have taken SGAs continuously for one year after the first MPC measurement had been performed. The change of MPC was verified through a paired sample t-test. Results : The result revealed that the mean MPC value was significantly decreased from 26.5±1.4 g/dL to 25.6±1.8 g/dL after 1-year administration of SGAs from the time of the first MPC measurement. Conclusions : This study suggests that 1-year administration of SGAs may be related with increased platelet activity, and that close monitoring for risks such as cerebrovascular/cardiovascular or thromboembolic diseases may be necessary during SGAs treatment in clinical practice.

A Study on the Development of "Bufo gargarizans" Habitat Suitability Index(HSI) (두꺼비 서식지 적합성 지수(HSI) 모델개발을 위한 연구)

  • Cho, Gun-Young;Koo, Bon-Hak
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.25 no.2
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    • pp.23-38
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    • 2022
  • This study investigates the characteristics and physical habitat requirements for each Bufo gargarizans life history through a literature survey. After deriving variables for each component of Bufo gargarizans, in order to reduce regional deviations from eight previously studied literature research areas for deriving the criteria for variables, a total of 12 natural habitats of Bufo gargarizanss are selected as spatial ranges by selecting four additional sites such as Umyeonsan Ecological Park in Seoul, Wonheungibangjuk in Cheongju in the central region, Changnyeong Isan Reservoir in the southern region, and Mangwonji in Daegu. This study presents Bufo gargarizans SI, a species endemic to Korea, whose population is rapidly declining due to large-scale housing site development and road development, and develops a Bufo gargarizans HSI model accordingly to improve the function of the damaged Bufo gargarizans habitat and to present an objective basis for site selection of alternative habitat. At the same time, it provides basic data for adaptive management and follow-up monitoring. The three basic habitat requirements of amphibians, the physical habitat requirements of Bufo gargarizans, synthesized with shelter, food, and water, and the characteristics of each life history, are classified into five components by adding space and threats through literature research and expert advice. Variables are proposed by synthesizing and comparing the general characteristics of amphibians, among the previously studied single species of amphibians, the components of HSI of goldfrogs and Bufo gargarizans, and the ecological and physical environmental characteristics of Bufo gargarizans. Afterwards, through consultation with an amphibian expert, a total of 10 variables are finally presented by adjacent forest area(ha), the distance between spawning area and the nearest forest land(m), the soil, the distance from the wetland(m), the forest layered structure, the low grassland space, the permanent wetland area(ha), shoreline slope(%), PH, presence of predators, distance from road(m), presence or absence of obstacles. n order to derive the final criteria for each of the 10 variables, the criteria(alternative) for each variable are presented through geographic information analysis of the site survey area and field surveys of the previously studied literature research area. After a focus group interview(FGI) of 30 people related to the Bufo gargarizans colony in Cheongju, a questionnaire and in-depth interviews with three amphibians experts are conducted to verify and supplement the criteria for each final variable. Based on the finally developed Bufo gargarizans HSI, the Bufo gargarizans habitat model is presented through the SI graph model and the drawing centering on the Bufo gargarizans spawning area

Effects of Planting Density and Fertilizer Level on the Growth, Yield, Quality and Nitrogenous Compounds of Burley Tobacco (재식밀도 및 시비량이 버어리종 잎담배의 생육, 수량, 품질 및 질소화합물에 미치는 영향)

  • Kim, Sang-Beom;Han, Chul-Soo;Ryu, Ik-Sang
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.32 no.1
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    • pp.40-47
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    • 1987
  • Under the different conditions of planting density and compound fertilizer level, some agronomic and chemical characteristics of burley tobacco were investigated from 1982 to 1984. Leaf area and dry leaf weight per plant, crop growth rate, relative growth rate and net assimilation rate for 40-60 days after transplanting were higher with increasing plant spacing and fertilizer, but leaf area index was lower with increasing plant spacing. At topping stage, the leaf size was increased with increasing plant spacing and amount of fertilizer applied and the stem diameter was increased by increasing plant spacing. Leaf area, leaf weight per plant and weight per unit leaf area of harvested leaf were higher when plant spacing and fertilizer increased. It was estimated that the optimum plant spacing was 105cm x 34cm and level of com-pound fertilizer (N-P$_2$ O$\sub$5/ -K$_2$O =10-10-20) was 263kg/l0a for high yield. There were trends toward increase the contents of total alkaloid and total nitrogen with increasing plant spacing and fertilizer application. There was significant positive correlation between plant spacing and total nitrogen, and between fertilizer application and total nitrogen. The plant spacing of 105cm x 35 to 40cm and 227.5kg/l0a of fertilizer level may be profitable for farm economy and the low nitrogenous leaf.

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Geomorphological and Sedimentological Characteristics of Jangdo Wetland in Shinan-gun, Korea (신안 장도습지의 지형과 퇴적물 특성)

  • CHOI, Kwang Hee;CHOI, Tae-Bong
    • Journal of The Geomorphological Association of Korea
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    • v.17 no.2
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    • pp.63-76
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    • 2010
  • The Jangdo wetland is located on a very gentle slope of the mountain area in Daejangdo island, Shinan-gun, Korea, in which the area of the watershed is estimated at 147,000 m2. The wetland has been regarded as a peat bog without any sedimentological evidence. This study was conducted to analyze the geomorphological and sedimentological characteristics of the wetland. The geographic information system (GIS) was used to analyze the drainage system, and field surveys were conducted to measure the range and depth of wetland deposits. The grain size analysis, organic matter determination, elements analysis and radiocarbon dating were performed on samples from the wetland. As a result, the wetland deposits were about 30 cm deep on average, the mean grain sizes ranged from 50 to 500 μm, and the average C/N ratio was 11.5. The portion of organic matter it contained was only 5~26%, which did not satisfy the peat standards. The radiocarbon ages from the wetland deposits range 180±50 14C yr BP to modern, which indicated that natural and anthropogenic interferences including agricultural activities have continuously happened. We conclude that the Jangdo wetland is still in its infancy, not a steady state, so that it could be very sensitive to a small disturbance.

Available phosphorus levels modulate gene expression related to intestinal calcium and phosphorus absorption and bone parameters differently in gilts and barrows

  • Julia Christiane Votterl;Jutamat Klinsoda;Simone Koger;Isabel Hennig-Pauka;Doris Verhovsek;Barbara U. Metzler-Zebeli
    • Animal Bioscience
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    • v.36 no.5
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    • pp.740-752
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    • 2023
  • Objective: Dietary phytase increases bioavailability of phytate-bound phosphorus (P) in pig nutrition affecting dietary calcium (Ca) to P ratio, intestinal uptake, and systemic utilization of both minerals, which may contribute to improper bone mineralization. We used phytase to assess long-term effects of two dietary available P (aP) levels using a one-phase feeding system on gene expression related to Ca and P homeostasis along the intestinal tract and in the kidney, short-chain fatty acids in stomach, cecum, and colon, serum, and bone parameters in growing gilts and barrows. Methods: Growing pigs (37.9±6.2 kg) had either free access to a diet without (Con; 75 gilts and 69 barrows) or with phytase (650 phytase units; n = 72/diet) for 56 days. Samples of blood, duodenal, jejunal, ileal, cecal, and colonic mucosa and digesta, kidney, and metacarpal bones were collected from 24 pigs (6 gilts and 6 barrows per diet). Results: Phytase decreased daily feed intake and average daily gain, whereas aP intake increased with phytase versus Con diet (p<0.05). Gilts had higher colonic expression of TRPV5, CDH1, CLDN4, ZO1, and OCLN and renal expression of TRPV5 and SLC34A3 compared to barrows (p<0.05). Phytase increased duodenal expression of TRPV5, TRPV6, CALB1, PMCA1b, CDH1, CLDN4, ZO1, and OCLN compared to Con diet (p<0.05). Furthermore, phytase increased expression of SCL34A2 in cecum and of FGF23 and CLDN4 in colon compared to Con diet (p<0.05). Alongside, phytase decreased gastric propionate, cecal valerate, and colonic caproate versus Con diet (p<0.05). Phytase reduced cortical wall thickness and index of metacarpal bones (p<0.05). Conclusion: Gene expression results suggested an intestinal adaptation to increased dietary aP amount by increasing duodenal trans- and paracellular Ca absorption to balance the systemically available Ca and P levels, whereas no adaption of relevant gene expression in kidney occurred. Greater average daily gain in barrows related to higher feed intake.

Target Reliability Indices of Static Design Methods for Driven Steel Pipe Piles in Korea (국내 항타강관말뚝 설계법의 목표 신뢰도지수)

  • Kwak, Kiseok;Huh, Jungwon;Kim, Kyung Jun;Park, Jae Hyun;Lee, Juhyung
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.28 no.1C
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    • pp.19-29
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    • 2008
  • As a part of study to develop LRFD (Load and Resistance Factor Design) codes for foundation structures in Korea, reliability analyses for driven steel pipe piles are performed and the target reliability indices are selected carefully. The 58 data sets of static load tests and soil property tests conducted in the whole domestic area were collected and analyzed to determine the representative bearing capacities of the piles. The static bearing capacity formula and the Meyerhof method using N values are applied to calculate the expected design bearing capacity of the piles. The resistance bias factors were evaluated for the two static design methods by comparing the representative bearing capacities with the design values. Reliability analysis was performed by two types of advanced methods: First Order Reliability Method (FORM), and Monte Carlo Simulation (MCS) method using resistance bias factor statistics. The static bearing capacity formula exhibited relatively small variation, whereas the Meyerhof method showed relatively high inherent conservatism in the resistance bias factors. Reliability indices for safety factors in the range of 3 to 5 were evaluated respectively as 1.50~2.89 and 1.61~2.72 for both of the static bearing capacity formula and the Meyerhof method. The target reliability indices are selected as 2.0 and 2.33 for group pile case and 2.5 for single pile case, based on the reliability level of the current design practice and considering redundancy of pile group, acceptable risk level, construction quality control, and significance of individual structure.

The Development and Validation of the Leisure Obsession Scale (여가강박 척도의 개발 및 타당화 연구)

  • Jiyeon Yoon;Seung-Hyuk Choi;Taekyun Hur
    • Korean Journal of Culture and Social Issue
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    • v.19 no.2
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    • pp.235-257
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    • 2013
  • The purpose of this study is to develop the Leisure Obsession Scale and examine the validity of the scale. The Leisure Obsession Scale was developed and identified its validity by exploratory factor analysis, confirmatory factor analysis, and correlation analysis. The Leisure Obsession Scale consists of two factors, which are 'Leisure Preoccupation' and 'Leisure Stereotype'. Those two factors indicated the reasonable fit index by confirmatory factor analysis. In addition, this scale displayed discriminant validity via measurement of obsession, workaholism, leisure anxiety, and leisure constraint. Also, the results of criterion validation analysis shows that the Leisure Obsession Scale and its subscale are correlated with measure of age, leisure information searching, intention of participation to new leisure activities, and intention of increase in leisure time. Conceptualizing leisure obsession and exploring components of leisure obsession would be valuable for understanding the nature of leisure obsession and its effects on leisure satisfaction, and suggesting more effective psychological intervention in a diverse population.

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Evaluation of Growth and Yield on Transplanting time and Plant Density in ItalianRyegrass

  • Yun-Ho Lee;Hyeon-Soo Jang;Jeong-Won Kim;Bo-kyeong Kim;Deauk-Kim;Jong-Tak Youn
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.101-101
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    • 2022
  • In recent years, due to climate change, the livestock industry has become more interested in the production of forage crops. In Korea, more than 74% of forage crops are cultivated in winter rice fields. In particular, Italian ryegrass (IRG) is depends on imports for more than 70% of its seeds. In generally, the IRG rapeseed cultivation method involves sowing from early October to mid-October by drill sowing seeding or spot seedling. However, the sowing period is delayed due to frequent rainfall during. And, same period require a lot of seeds. However, raising seedlings and transplanted IRG will overcome weather conditions and reduce the amount of seeds. This study was intended to be applied to the domestic IRG seed industry in the future through growth and quantity evaluation according to transplant time and planting density for the production of good quality IRG seeds in rice paddy fields. In this study, transplanting time (October 20, October 30, November 10) and planting density (50, 70, and 80) were cultivated at the National Institute of Crop Science in 2021. The amount of fertilizer applied was adjusted to (N-P2O5-K2O) 4.5-12-12 (kg/10a), and then 2.2(kg/10a) of nitrogen was added each year. For the growth survey, leaf area, canopy coverage, plant length, and seed yield were investigated. Along with the transplanting time, the plant length was higher on October 20 than on October 30 and November 10. On the other hand, leaf area index changes differed depending on the transplanting time and planting density, and were particularly high on October 20, 80 density and 70 density, but similar on October 30 and November 10. 1000 seed weight showed no difference with transplanting time and planting density. On the other hand, the seed yield was 215(kg/10a) for 80 density on October 20, 211(kg/10a) for 70 density, 118(kg/10a) for 50 density, and 80 density for October 30 and November 10. and 70 density did not differ. On the other hand, the 50 density on October 30 and November 10 were 164(kg/10a) and 147(kg/10a) respectively. As can be seen from this study, the earlier the transplant, the higher the seed yield. However, the 50 density was reduced in yield compared to the 70 density and 80 density.

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Characteristics of Seedling Quality of Rhus javanica L. 1-year-old Container Seedling by Fertilization Level (붉나무 1년생 용기묘의 시비수준별 묘목품질 특성)

  • Yang Soo Kim;Sang Geun Kim;Jung Suk Um;Geun Sik Kim;Ki Seon Song;Jae Sun Yi
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2022.09a
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    • pp.74-74
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    • 2022
  • 본 연구는 붉나무의 기능성 성분의 산업화 활용을 위한 고품질의 붉나무 1년생 용기묘 대량생산을 위해 실시되었다. 붉나무 1년생 용기묘의 묘목품질의 향상을 위해 다양한 농도의 시비처리하여 우량묘 생산에 적합한 시비수준을 구명하고자 하였다. 시비실험은 무시비구 포함하여 수용성 복합비료 (N:P:K=20:20:20, v/v)를 1,000mg·L-1, 2,000mg·L-1, 3,000mg·L-1 수준으로 실시하였다. 시비처리는 붉나무 용기묘의 간장과 근원경 생장은 1,000mg·L-1 시비처리구에서 생장이 가장 좋게 나타났으며 시비수준이 증가할수록 감소하는 경향을 보였다. 뿌리형태 특성분석에서도 전체뿌리길이, 투영단면적, 표면적 및 뿌리부피가 간장과 근원경 생장과 동일한 경향을 보이는 것으로 조사되었다. 건물 생산량은 부위별 잎, 줄기, 뿌리 및 전체가 모두 1,000mg·L-1 시비처리구에서 가장 높았으며, 그 이상의 시비수준에서는 점점 감소하는 경향을 보였다. H/D(Hight/Root collar diameter)율은 전체가 3.82(무시비구) ~ 4.90, T/R(Top/Root)율은 전체가 0.56(1,000mg·L-1 시비처리구) ~ 0.82로 조사되었다. 시비처리 에 의한 붉나무의 LWR(Leaf dry weight ratio)은 무시비구, SWR(Shoot dry weight ratio)은 3,000mg·L-1 시비처리구, 그리고 RWR(Root dry weight ratio)은 1,000mg·L-1 시비처리구에서 유의적 차이를 보이며 높게 나타났다. 묘목품질지수(QI)의 경우 1,000mg·L-1 시비처리구에서 12.13으로 다른 시비수준들보다 월등히 높았다. 본 실험의 결과를 종합하면, 뿌리발달이 좋은 우량한 붉나무 생산에 적절한 시비수준은 1,000mg·L-1 정도인 것으로 판단된다.

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