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Development of Walkability Search System (보행친화도 검색 시스템 개발)

  • Kim, Eun Jung;An, Donghyeok
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.9 no.12
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    • pp.987-997
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    • 2019
  • Walk score, walkablity index of built environmental condition, has developed and used in everyday life in United States. The purpose of this study is to produce walk score in Seoul, and to develop computer-based walk score system for improving it's usage. This study covers city of Seoul, and the unit of spatial analysis is 100m × 100m grid cell. This study uses same methodology with walk score in US, the Geographic Information Systems(GIS) is used for calculating the values of walk score(N=58,062). This study implemented Java-based system that utilizes walk score dataset(latitude, longitude, and walk score). This system provided search functions including both lat/long-based and address-based options. Meanwhile, this system was designed to provide the closest value of walk score in dataset if location did not match the certain points in dataset. This study has significance to provide walk score system being easily available to all.

3DCGI workflow proposal for reduce rendering time of drama VFX (드라마 VFX의 렌더링 시간 단축을 위한 3DCGI 워크플로우 제안)

  • Baek, Kwang Ho;Ji, Yun;Lee, Byung Chun;Yun, Tae Soo
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.24 no.8
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    • pp.1006-1014
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    • 2020
  • Consumer expectations for drama VFX increased as the influx of overseas dramas increased due to the growth of OTT service, but the current production time of the drama production system has a negative effect on the quality and completion of work. This paper proposes a background rendering using a game engine and a subject rendering using background HDRI as environmental lighting. The proposed workflow is expected to reduce the production time of VFX and improve the quality of VFX. The proposed workflow was verified in 3 steps. Comparing game engine and rendering software according to the same lighting environment and camera distance, comparing rendering with existing rendering method and background HDRI generation, and validating the proposed workflow. For verification, quantitative evaluation was performed using Structual similarity index and histogram. This study is expected to be one of the options to improve the quality of VFX and improve the risk.

Long-Term Efficacy and Safety of Golimumab for Ulcerative Colitis in a Pediatric Inflammatory Bowel Disease Center in Japan

  • Tokita, Kazuhide;Shimizu, Hirotaka;Takeuchi, Ichiro;Shimizu, Toshiaki;Arai, Katsuhiro
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.25 no.6
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    • pp.461-472
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    • 2022
  • Purpose: Golimumab (GLM) is an anti-tumor necrosis factor (TNF)-α antibody preparation known to be less immunogenic than infliximab (IFX) or adalimumab. Few reports on GLM in pediatric patients with ulcerative colitis (UC) are available. This study aimed to review the long-term durability and safety of GLM in a pediatric center. Methods: The medical records of 17 pediatric patients (eight boys and nine girls) who received GLM at the National Center for Child Health and Development were retrospectively reviewed. Results: The median age at GLM initiation was 13.9 (interquartile range 12.0-16.3) years. Fourteen patients had pancolitis, and 11 had severe disease (pediatric ulcerative colitis activity index ≥65). Ten patients were biologic-naive, and 50% achieved corticosteroid-free remission at week 54. Two patients discontinued prior anti-TNF-α agents because of adverse events during remission. Both showed responses to GLM without unfavorable events through week 54. However, the efficacy of GLM in patients who showed primary nonresponse or loss of response to IFX was limited. Four of the five patients showed non-response at week 54. Patients with severe disease had significantly lower corticosteroid-free remission rate at week 54 than those without severe disease. No severe adverse events were observed during the study period. Conclusion: GLM appears to be safe and useful for pediatric patients with UC. Patients with mild to moderate disease who responded to but had some adverse events with prior biologics may be good candidates for GLM. Its safety and low immunogenicity profile serve as favorable options for selected children with UC.

A Case Report of Postherpetic Neuralgia Treated with Kyung Hee Gongjin-dan and Hyangbujapalmul-tang-gagam (경희공진단과 향부자팔물군자탕가감으로 호전된 대상포진 후 신경통 치험 1례)

  • Jeon, Gyu-Ri;Yim, Tae-Bin;Hwang, Ye-Chae;Heo, Hye-Min;Cho, Seung-Yeon;Park, Seong-Uk;Ko, Chang-Nam;Park, Jung-Mi
    • The Journal of Internal Korean Medicine
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    • v.43 no.5
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    • pp.980-988
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    • 2022
  • The most common definition of postherpetic neuralgia is the presence of pain more than a month after the onset of the eruption of zoster. This case report suggests the effect of Korean medicine on postherpetic neuralgia. An 85-year-old male patient with postherpetic neuralgia was treated with a combination of Korean medical remedies. Kyung Hee Gongjin-dan and Hyangbujapalmul-tang-gagam were applied for 23 days. The Numerical Rating Scale was used to measure pain intensity. The Barthel Index and Beck Depression Inventory were used for the functional assessment and depression evaluation, respectively. After treatment, the patient's pain intensity decreased. Additionally, the patient's independence increased during activity, and the severity of their depression decreased. Thus, this case suggests that a combination of Korean medicine treatments might be effective for postherpetic neuralgia. In particular, it shows that Kyung Hee Gongjin-dan and Hyangbujapalmul-tang-gagam can be therapeutic options in the treatment of postherpetic neuralgia.

Cost Normalization Framework for a Benchmarking System: A Case for Downstream and Chemical Construction Projects

  • Yin, Zhe;DeGezelle, Deborah;Pappas, Mike;Caldas, Carlos
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.590-598
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    • 2022
  • Benchmarking is an important tool to assess the performance of capital projects in the construction industry. Incorporating cost-related metrics into a benchmarking system requires an effective cost normalization process to enable meaningful comparisons among projects that were executed at different locations and times. Projects in the downstream and chemicals sector have unique characteristics compared to other types of construction projects, they require a distinctive cost normalization framework to be developed to benchmark their absolute cost performance. The purpose of this study is to develop such a framework to be used for the case of benchmarking the downstream and chemical projects for their performance assessment. The research team started with a review of existing cost normalization methodologies adopted in benchmarking systems and conducted 7 interviews to identify the current cost normalization practices used by industrial professionals. A panel of 12 experts was then convened and it held 6 review sessions to accomplish the framework development. The cost normalization framework for benchmarking downstream and chemical projects was established as a three-step procedure and it adopts a 4-element cost breakdown structure to accommodate projects submitted by both owners and contractors. It also incorporated 5 published cost indexes that are compatible with downstream and chemical projects and they were embedded into 2 options to complete the normalization process. The framework was then pilot-tested on 4 completed projects to validate its functional practicality and the downstream and chemical use case in the benchmarking system.

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Evaluation of genetic differentiation and search for candidate genes for reproductive traits in pigs

  • Elena Romanets;Siroj Bakoev;Timofey Romanets;Maria Kolosova;Anatoly Kolosov;Faridun Bakoev;Olga Tretiakova;Alexander Usatov;Lyubov Getmantseva
    • Animal Bioscience
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    • v.37 no.5
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    • pp.832-838
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    • 2024
  • Objective: The use of molecular genetic methods in pig breeding can significantly increase the efficiency of breeding and breeding work. We applied the Fst (fixsacion index) method, the main focus of the work was on the search for common options related to the number of born piglets and the weight of born piglets, since today the urgent task is to prevent a decrease in the weight of piglets at birth while maintaining high fertility of sows. Methods: One approach is to scan the genome, followed by an assessment of Fst and identification of selectively selected regions. We chose Large White sows (n = 237) with the same conditions of keeping and feeding. The data were collected from the sows across three farrowing. For genotyping, we used GeneSeek GGP Porcine HD Genomic Profiler v1, which included 68,516 single nucleotide polymorphisms evenly distributed with an average spacing of 25 kb (Illumina Inc, San Diego, CA, USA). Results: Based on the results of the Fst analysis, 724 variants representing selection signals for the signs BALWT, BALWT1, NBA, and TNB (weight of piglets born alive, average weight of the 1st piglets born alive, total number born alive, total number born). At the same time, 18 common variants have been identified that are potential markers for both the number of piglets at birth and the weight of piglets at birth, which is extremely important for breeding work to improve reproductive characteristics in sows. Conclusion: Our work resulted in identification of variants associated with the reproductive characteristics of pigs. Moreover, we identified, variants which are potential markers for both the number of piglets at birth and the weight of piglets at birth, which is extremely important for breeding work to improve reproductive performance in sows.

Univariate and Multivariate Analysis of Phenotypic Traits in Mung Beans Reveals Diversity Among Korean, Indian, and Chinese Accessions

  • Kebede Taye Desta;Young-ah Jeon;Myoung-Jae Shin;Yu-Mi Choi;Jungyoon Yi;Hyemyeong Yoon
    • Korean Journal of Plant Resources
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    • v.37 no.3
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    • pp.270-306
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    • 2024
  • This study investigated the diversity of 323 mung bean accessions from Korea, China, and India, along with six cultivars, using 22 agronomical traits. The standardized Shannon-Weaver index (H') for the qualitative traits ranged from 0.11 (terminal leaflet shape) to 0.98 (pubescence density of pod). Likewise, the coefficient of variation for the quantitative traits ranged from 8.76% (days to maturity (DM)) to 79.91% (lodging rate (LR)), indicating a wide genetic variance. Hypocotyl color, pod color, seed shape, and seed coat surface lust showed different distributions among Korean, Indian, and Chinese accessions. Chinese accessions had the highest average germination rate, DM, days from flowering to maturity, and one-hundred seeds weight, followed by Korean and Indian accessions, while the number of seeds per pod (SPP) displayed the opposite trend, with all except SPP showing significant variation (p < 0.05). Similarly, plant height, days to flowering, and number of pods per plant increased in the order of India > Korea > China, with LR showing the opposite trend (p < 0.05). The mung bean accessions were grouped into four major clusters using hierarchical cluster analysis supported by principal component analyses, and all of the quantitative traits showed significant variations between the clusters (p < 0.05). Generally, the mung bean accessions investigated in this study exhibited wide phenotypic trait variations, which could be beneficial for future genomics studies. Moreover, this study identified 77 accessions that outperformed the controls. Consequently, these superior accessions could provide a wide spectrum of options during the development of improved mung bean varieties.

R Based Parallelization of a Climate Suitability Model to Predict Suitable Area of Maize in Korea (국내 옥수수 재배적지 예측을 위한 R 기반의 기후적합도 모델 병렬화)

  • Hyun, Shinwoo;Kim, Kwang Soo
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.19 no.3
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    • pp.164-173
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    • 2017
  • Alternative cropping systems would be one of climate change adaptation options. Suitable areas for a crop could be identified using a climate suitability model. The EcoCrop model has been used to assess climate suitability of crops using monthly climate surfaces, e.g., the digital climate map at high spatial resolution. Still, a high-performance computing approach would be needed for assessment of climate suitability to take into account a complex terrain in Korea, which requires considerably large climate data sets. The objectives of this study were to implement a script for R, which is an open source statistics analysis platform, in order to use the EcoCrop model under a parallel computing environment and to assess climate suitability of maize using digital climate maps at high spatial resolution, e.g., 1 km. The total running time reduced as the number of CPU (Central Processing Unit) core increased although the speedup with increasing number of CPU cores was not linear. For example, the wall clock time for assessing climate suitability index at 1 km spatial resolution reduced by 90% with 16 CPU cores. However, it took about 1.5 time to compute climate suitability index compared with a theoretical time for the given number of CPU. Implementation of climate suitability assessment system based on the MPI (Message Passing Interface) would allow support for the digital climate map at ultra-high spatial resolution, e.g., 30m, which would help site-specific design of cropping system for climate change adaptation.

Knee Joint Sparing Tumor Resection in 4years-Old Patient with Osteosarcoma - A Case Report - (4세 소아 대퇴골 골육종의 슬관절 보존형 절제 및 재건술 - 증례 보고 -)

  • Cho, Wan-Hyung;Cho, Sang-Hyun;Won, Ho-Hyun;Jeon, Dae-Geun
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.2
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    • pp.157-162
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    • 2008
  • Nowadays, most of the malignant bone tumor patient underwent limb salvage operation, however, reconstructive options for skeletally immature group are still controversial. There are three necessary conditions of most ideal reconstructive method in treating the skeletally immature children. As the epiphyseal plate sacrification is usually inevitable in malignant bone tumor around knee joint, ideal reconstructive technique would be as follows; 1)minimal or no damage to theadjacent epiphyseal plate, 2) maintaining mobile joint, 3) index procedure does not disturb subsequent operation such as lengthening. Segmental resection and reconstruction using autogenous pasteurized graft was done for 4 years old meta-diaphyseal osteosarcoma of femur. At 6 months from index operation, plain radiograph showed pasteurized bone resorption and loosening of fixation devise. To overcome the complication, we used allograft reconstruction by impacting the proximal host bone to the fluted portion of allobone. Three months later, proximal bone union was observed and patient showed good functional outcome.

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Comparison of Awareness of Symptoms and Illness Between Patients with Obstructive Sleep Apnea and Simple Snoring (수면무호흡증과 단순 코골이 환자의 증상과 질환 인식도 비교)

  • Lee, Seyoung;Kang, Jae Myeong;Cho, Yoon-Soo;Yoon, Hyun Jin;Kim, Ji-Eun;Shin, Seung-Heon;Park, Kee Hyung;Kim, Seon Tae;Kang, Seung-Gul
    • Sleep Medicine and Psychophysiology
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    • v.23 no.1
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    • pp.16-24
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    • 2016
  • Background and Objectives: Obstructive sleep apnea (OSA) is often undiagnosed but is an important risk factor affecting the health of an individual. The level of awareness of the illness among patients with OSA is low and is not correlated with severity of the illness. This study was conducted to compare awareness of OSA symptoms and illness between patients with OSA and simple snorers. Materials and Methods: Two hundred eighty-two patients who were suspected of having OSA participated in this study. All subjects underwent overnight polysomnography. Those with an apnea-hypopnea index (AHI) ${\geq}5$ were classified as the OSA group, while those with an AHI < 5 were classified as the simple snoring group. A sleep questionnaire, which included items on awareness of the illness, OSA, and sleep symptoms, was administered to all subjects and their bed-partners. Results: Simple snorers were much more aware of their symptoms such as snoring, irregular breathing, and apnea than were patients with OSA. Bed-partners of simple snorers were also more aware of the participants' sleep symptoms than were partners of patients with OSA. However, the duration of OSA symptoms was longer in the OSA group. In the correlation analysis, the level of awareness of OSA symptoms was negatively correlated with AHI, age, body mass index, and Epworth Sleepiness Scale score. Among the sleep questionnaire and polysomnography results, only Pittsburgh Sleep Quality Index was positively correlated with level of awareness of OSA symptoms. The minority of the respondents had heard about the treatment methods of continuous positive airway pressure and oral appliance and preferred them as treatment options. Conclusion: This study suggests that simple snorers are more aware of their symptoms than are patients with OSA. A higher severity of OSA, represented by a higher AHI, is correlated with lower awareness of one's OSA symptoms.