• Structural Engineering and Mechanics
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• v.54 no.6
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• pp.1153-1174
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• 2015

Deployable structures have gained more and more applications in space and civil structures, while it takes a large amount of computational resources to analyze this kind of multibody systems using common analysis methods. This paper presents a new approach for dynamic analysis of multibody systems consisting of both rigid bars and arbitrarily shaped rigid bodies. The bars and rigid bodies are connected through their nodes by ideal pin joints, which are usually fundamental components of deployable structures. Utilizing the Moore-Penrose generalized inverse matrix, equations of motion and constraint equations of the bars and rigid bodies are formulated with nodal Cartesian coordinates as unknowns. Based on the constraint equations, the nodal displacements are expressed as linear combination of the independent modes of the rigid body displacements, i.e., the null space orthogonal basis of the constraint matrix. The proposed method has less unknowns and a simple formulation compared with common multibody dynamic methods. An analysis program for the proposed method is developed, and its validity and efficiency are investigated by analyses of several representative numerical examples, where good accuracy and efficiency are demonstrated through comparison with commercial software package ADAMS.

• Animal cells and systems
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• v.10 no.3
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• pp.115-120
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• 2006

Parkinson's disease (PD) is a neurodegenerative disease caused by selective degeneration of dopaminergic neurons in the substantia nigra. Mutations in ${\alpha}$-synuclein have been causally linked to the pathogenesis of hereditary PD. In addition, it is a major component of Lewy body found in the brains of sporadic cases as well. In the present study, we examined whether overexpression of wild type or PD-related mutant ${\alpha}$-synuclein induces unfolded protein response (UPR) and triggers the known signaling pathway of the resulting endoplasmic reticulum (ER) stress in SH-SY5Y cells. Overexpression of wild type, A30P, and A53T ${\alpha}$-synuclein all induced XBP-1 mRNA splicing, one of the late stage UPR events. However, activation of ER membrane kinases and upregulation of ER or cytoplsmic chaperones were not detected when ${\alpha}$-synuclein was overexpressed. However, basal level of cytoplsmic calcium was elevated in ${\alpha}$-synuclein-expressing cells. Our observation suggests that overexpression of ${\alpha}$-synuclein induces UPR independent of the known ER membrane kinase-mediated signaling pathway and induces ER stress by disturbing calcium homeostasis.

• Journal of Fashion Business
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• v.9 no.6
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• pp.86-100
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• 2005

This paper has examined how ugliness has aesthetically been portrayed in modern make-up. In the past, ugliness was regarded as an antonym of beauty, but it recently plays a role on part of beauty, as independent portion of art. It was Schegel who initially maintained the view. According to his theory, ugliness represents interesting things including suffering reality, shock, attention, humor, surprises brought by distort and deformation. Hegel had a different view on it. As for him, he had the notion that ugliness was the opposite to beauty and that it had to be dependent in art, he argued that art was subordinate to philosophy, and that it was just nostalgia for the past, not representing reality, therefore, it could not be a foothold in contemporary art. In this context, some images of ugliness can be classified accordingly to Schegel's view deteste, decadence and androgynous can be fallen into a category describing reality; fetish, kitsch and grotesque can be included in interesting things. There is no fine line between the two. There are sometimes things they have in common. They mutually draw attentions by distancing themselves from general images of beauty, or making many changes and distorts in its part, using unique materials, unprecedented attempts of colors which result in creative and shocking images. Attempts made in ugly images in modern art are widening its concept to depicting reality on the body of human beings, also creating its new definition, playing a major role in independent part of modern art, not in the past way like wearing make-up on the face to make it look better.

• Food Science and Industry
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• v.50 no.1
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• pp.2-10
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• 2017

Human have eaten various traditional fermented foods for a numbers of million years for health benefit as well as survival. The beneficial effects of fermented foods have been resulted from complex microbial communications within the fermented foods. Therefore, the holistic approaches for individual identification and complete microbial profiling involved in their communications have been of interest to food microbiology fields. Microbiome is the ecological community of microorganisms that literally share our environments including foods as well as human body. However, due to the limitation of culture-dependent methods such as simple isolations of just culturable microorganisms, the culture-independent methods have been consistently developed, resulting in new light on the diverse non-culturable and hitherto unknown microorganisms, and even microbial communities in the fermented foods. For the culture-independent approaches, the food microbiome has been deciphered by employing various molecular analysis tools such as fluorescence in situ hybridization, quantitative PCR, and denaturing gradient gel-electrophoresis. More recently, next-generation-sequencing (NGS) platform-based microbiome analysis has been of interest, because NGS is a powerful analytical tool capable of resolving the microbiome in respect to community structures, dynamics, and activities. In this overview, the development status of analysis tools for the fermented food microbiome is covered and research trend for NGS-based food microbiome analysis is also discussed.

• Fashion & Textile Research Journal
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• v.14 no.6
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• pp.968-976
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• 2012

This study presents a new method called the SPMP (Semi-automatic profile measuring program) to efficiently measure body shape in elderly women. SPMP can automatically measure the angle of axis (19 items), surface (17 items), lengths (14 items), heights (16 items), widths (13 items), and depth (6 items). In total these 85 items are automatically measured very quickly, accurately, and easily after manually marking an initial 36 points. The utility of SPMP was evaluated using several tests. When SPMP measuring results were compared with manual methods (using a ruler and protractor) in thirteen elderly women using a paired t-test, there was no significant difference found between them. Furthermore, when measurements from SPMP were compared with actual measurement results in selected items from seven elderly women's measurements, smaller mean differences were found than those defined by ISO 20685, with the exception of the abdominal area which moves easily with breathing. Seven independent measurements of a single elderly woman were made by seven students using SPMP, and the values of coefficient of variation were less than 5% for all but 8 items. Finally, this study analyzed the correlation of all 85 item measurements, and found that the angle from the upper chest to the neck towards the front in the axis curved forward as much as the axis angle from the thigh to the waist (r=-0.876, $^{**}p$ < 0.01) bent backwards in elderly women. This detailed analysis helps to understand age-related changes in body posture, and will be useful in future studies.

• Journal of Environmental Science International
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• v.24 no.1
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• pp.117-131
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• 2015

Purpose: In this study a pilates exercise program using self-efficacy sources was provided for women 65 years of age or older and the effects on physical fitness, body composition, depression, self-efficacy, and health-related quality of life were tested. Methods: A quasi-experimental study employing a nonequivalent control group, pre-post design was conducted. The subjects consisted of 30 older women in the experiment group and 30 in the comparison group. The intervention was conducted twice a week for a period of 12 weeks. During this period, the pilates exercise program using self-efficacy sources (health education, phone coaching, mentoring, checking homework, recreation) were provided in the experiment group and pilates exercise program were offered in the comparison group. Chi-square test, independent t-test, ANCOVA were used for data analysis. Results: Following completion of the program, upper muscle strength (F=4.131, p=.047), low muscle strength (F=5.558, p=.022), upper flexibility (F=5.252, p=.026), static balance (F=5.957, p=.018), dynamic body balance & agility(F=18.971, p<.001), endurance(F=10.058, p=.002), muscle mass (F=5.748, p=.020), depression (F=4.493, p=.038), Self-efficacy (F=33.853, p<.001), and Health-related quality of life(F=5.586, p=.022) were significantly better in the experimental group. Conclusion: Findings from this study indicate that the pilates exercise program using self-efficacy sources are effective in enhancing physical fitness, body composition, self-efficacy and health-related quality of life and in decreasing depression for female elders and could therefore be regarded as positive program for promotion of physical and mental health for older women.

• Biomedical Science Letters
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• v.15 no.4
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• pp.301-307
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• 2009

Whole-body insulin resistance results largely from impaired insulin-stimulated glucose disposal in skeletal muscle. Our previous studies using differential display and quantitative real-time RT-PCR have shown that a novel cDNA band (DD23) had a higher level of expression in insulin resistant skeletal muscle and it was correlated with whole-body insulin action, independent of age, sex, and percent body fat. In this study, we cloned and characterized DD23. The DD23 sequence is part of the 3'UTR region of the RNA binding motif, single stranded interacting protein (RBMS3). We have cloned the full length cDNA for RBMS3 and identified two splice variants. These variants named DD23-L and DD23-S have 15 and 14 exons respectively and differ from RBMS3 in the 3'UTR significantly. Northern blot analyses showed that an ~8.8 kb mRNA transcript of DD23 was predominantly expressed in skeletal muscle and to a lesser extent in placenta, but not in heart, brain, lung, liver, or kidney, unlike RBMS3. Elevated expression levels of these novel alternatively spliced variants of RBMS3 in skeletal muscle may play a role in whole body insulin resistance.

• PNF and Movement
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• v.15 no.2
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• pp.185-194
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• 2017

Purpose: The purpose of this study was to prove the effects of the PNF patterns combined with whole-body vibration (PWBV) training on muscle strength, balance, walking speed, and endurance in stroke patients. Methods: Sixteen subjects were randomly assigned to the PWBV group (n=8) and the whole-body vibration (WBV) group (n=8). The PWBV group performed PNF pattern exercises using sprinter combined with WBV, while the WBV group performed using squatting for 30 minutes. Both groups performed therapeutic interventions five days per week over a period of four weeks. The manual muscle test, timed up and go test (TUG), 10-meter walk test (10MWT), and six-minute walk test (6MWT) were used to assess the muscle strength, balance, and gait of the participants. The SPSS Ver. 19.0 statistical program was used for data processing. Statistical analysis included a pared t-test to compare the pre- and post-intervention, and an independent t-test was used to compare groups. The significance level was set as 0.05. Results: The PWBV group and WBV group showed significant improvements in the TUG, 10MWT, and 6MWT (P<0.05). Significant differences between the PWBV and WBV groups were found (P<0.05). Conclusion: The PWBV improved muscle strength, balance, gait speed, and endurance in stroke patients. Thus, PWBV may be suggested as a therapeutic intervention in patients with stroke hemiplegia.

• The Korean Society of Law and Medicine
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• v.14 no.2
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• pp.217-260
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• 2013

In connection to the civil liability of the medical malpractice, plaintiff and courts are solving the medical disputes with theory of the liability based on tort law. because contract law does not enact the right of claim of solatium and a plaintiff's lawyer and courts hesitate to use contract law. Medical treatment of doctor is main debt in medical contract and its in-complete performance gives rise to the violations of human's life, body and health. Consequently a breach of medical contract leads to violations of person-al rights. These violations spring from liability of contract as well as tort and damages from them are recognized based on medical contract law. A duty of explanation of doctor is a independent and appendant debt to the treatment debt. However its breach provokes violations of human's life, body and health as well as a right self-determination. Therefore consolation money claim should be recognized. In case of the violation of patient's life, body and health, patient's family al-so can demand consolation money due to the violation of their's own mental pain. However in case of the violation of only patient's self-determination without informed concent, they can not demand it by reason of the violation of patient's self-determination. But by reason of the violation of patient's life, body and health that were recognized by proximate causal relation between violation of duty of explanation and abd execution, they can do.

• Korean Journal of Community Nutrition
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• v.7 no.1
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• pp.45-57
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• 2002

The purpose of this research of this research was to survey the health of 181 male and 130 female students at K University in Chunganm from June 1 to June 23, 2001. It analyzed the students’dietary behaviors, life styles and perceived body shapes and the correlation of these factors to the health condition of the students surveyed. The results of the survey are summarized as follows. The average nutrition knowledge score (out of a possible 20 points), dietary attitudes score (out of a possible 50 points) and dietary habits score (out of a possible 30 points) were 8.66, 33.14 and 19.02 for males, and 9.99, 32.64, and 19.05 for females, respectively. The percentages of those who smoked, drank, smoked and drank and exercised regularly were 55.2, 92.8, 54.1, 82.9% for males, and 6.9, 91.5, 6.9, 63.1 for females, respectively. A significantly higher proportion of males smoked, drank, and exercised as compared to females (p<0.001). The percentages of students who were underweight, normal or overweight by BMI were 5.0, 79.0 and 16.0 for males, and 20.0, 78.5 and 1.5 for females, respectively. Fifty percent of females indicated that they felt they were obese, versus only 31.1% of males. Half of the females thought they were fattish, while only 31.1% of males thought that. Seventy-six point nine percent of females and 61.9% of males, more females than males, were dissatisfied with their weights. The health scores (the higher the point, the better the health condition) of the females (44.17) were significantly lower than those of the males (47.17) (p<0.001). A stepwise multiple regression analysis with health scores as the dependent variable and other scores as independent variables, indicated that the health scores of males were highly correlated with satisfaction with his body weight, smoking and drinking, and perceived body shape, whereas the females’health scores were highly correlated with obesity level, satisfaction with her body weight, and smoking and drinking.