• Title/Summary/Keyword: Inclusion-Degree

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Breast animation deformity

  • Dyrberg, Diana Lydia;Bille, Camilla;Gunnarsson, Gudjon Leifur;Frandsen, Tove Faber;Salzberg, C. Andrew;Sorensen, Jens Ahm;Thomsen, Jorn Bo
    • Archives of Plastic Surgery
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    • v.46 no.1
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    • pp.7-15
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    • 2019
  • Breast animation deformity (BAD) has been reported to occur after submuscular implant placement following breast augmentation and immediate breast reconstruction. Despite its apparent impact on patients' quality of life, BAD has only recently become a topic of general concern. Its incidence and etiology have yet to be established. The aim of this systematic review was to identify papers that clearly defined and classified BAD and described how the degree of animation was assessed. We performed a search in PubMed and Embase. Studies meeting the inclusion criteria that described BAD after implant-based breast augmentation or immediate breast reconstruction were included. After screening 866 publications, four studies were included: three describing BAD after breast augmentation and one describing BAD after immediate breast reconstruction. The median percentage of patients with some degree of BAD was 58%. The highest percentages were found in patients operated on using the Regnault technique or the dual-plane technique (73%-78%). The lowest percentages were found following the dual-plane muscle-splitting technique (30%) and the triple-plane technique (33%). We found no studies meeting the inclusion criteria that analyzed BAD after prepectoral implant placement. This review of the current literature suggests that the degree of BAD is proportional to the degree of muscle involvement. Evidence is scarce, and the phenomenon seems to be underreported. Future comparative studies are warranted.

Studies on Host-Virus Interaction of Poxviruses 1. Cytochemical, Autoradiographic and Immunocytological Analysis in Cowpox Virus-FL Cell System (Poxvirus 감염(感染)에 있어서의 Virus-숙주세포(宿主細胞)의 상호관계(相互關係) 1. Cowpox Virus-FL 세포계(細胞系)의 세포화학적(細胞化學的) Autoradiography 및 세포면역학적해석(細胞免疫學的解析))

  • Kim, Uh Ho
    • Korean Journal of Veterinary Research
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    • v.15 no.1
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    • pp.57-67
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    • 1975
  • The poxvirus group is considered to be a typical cytoplasmic inclusion forming virus. Every poxvirus has been reported to produce only one kind of inclusion in the infected tissues. A vague concept that inclusions of poxviruses are eosinophilic or acidophilic has prevailed. Although many papers and theories about the nature of the inclusion have been presented, most of them are not quite convincing on the point of the relations with virus multiplication, and an analysis of papers published showed that there seem to be many discrepancies in the descriptions of the nature of the poxvirus inclusions. Comparative studies on host-virus interaction with cowpox, orf, swinepox and fowlpox viruses which selected from each Group (I-IV) of poxviruses were performed from the morphological and virological standpoints. At first, in cowpox virus-FL cell system, as a comparative model, cytoplasmic inclusion, nucleic acid metabolism by autoradiography and detection of viral antigen by immunofluorescence were studied and obtained the results as follows: 1. The focus-like cytopathic effect (CPE) at early stage developed to entire culture at terminal stage of infection, and also the developing status of CPE was correlated to viral doses for inoculation. Two kinds of cytoplasmic inclusions which named A and B type were easily observed by Giemsa, hematoxylin-eosin (H & E) and May-Greenwald Giemsa (MGG) stainings in the infected cells. The B type inclusions were formed at early stage of infection and the A type inclusions were produced subsequently the B type formation. The B type which common type inclusion in poxviruses was a small compact or aggregate at early stage and developed to a large diffuse body at terminal stage of infection. On the other hand, the A type inclusion which depend upon the kind of virus was appeared as round and discrete shape, and its size and number was increased gradually during the culture period. It was characteristic to form distinct halos around the both types of inclusions in acid fixed, H & E stained preparations of infected cultures. The B type inclusion was always positive in Feulgen reaction and showed as DNA containing body but the A type inclusion was not. 2. In the relationship between inclusion and DNA metabolism of infected cells by the qualitative autoradiography using 3H-thymidine, the appearance of silver grains was coincided with B type inclusion but not with A type inclusion. This showed that the DNA synthesis was proceeded in all B type inclusions except those in the terminal stage with a diffuse form. This suggested that the B type inclusions are only sites of DNA synthesis and this was proceeded after the cell infection independently. The activity of DNA synthesis of the inclusions was nearly the same as that of the nucleic of normal cells and non-inclusion bearing cells. and non-inclusion bearing cells. Regardless of the size of the degree of DNA synthesis of the B type inclusion, inclusion bearing cells all showed remarkable suppression of nuclear DNA synthesis. 3. By the direct fluorescent antibody technique viral antigen in infected cells was detected. The B type inclusions have been proved to contain a great deal of viral antigen, whereas the basic substance of A type inclusion did not show antigenicity except the round edge. It was suggested that the round edge fluorescence might be caused by the glare of cytoplasmic viral antigen which pushed out and concentrated by the A type inclusion development. 4. Hemorrhagic red pock formations on chorioallantoic membrane of embryonated chicken egg had proved the characteristic of used viral strain. 5. By the above studies on the nature of two types of inclusions and the role they play in virus multiplication, it was concluded that the B type inclusion must be the site of the synthesis of viral DNA and protein as well as the site of the virus.

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Modeling of the ITZ zone in concrete: Experiment and numerical simulation

  • Setiawan, Yanuar;Gan, Buntara S.;Han, Ay Lie
    • Computers and Concrete
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    • v.19 no.6
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    • pp.641-649
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    • 2017
  • The discovery of the Interfacial Transition Zone (ITZ) by Farran in 1956 initiated a new era in the study of the behaviour of concrete. Acknowledged as the weak link, this ITZ was studied extensively, numerically as well as experimentally. While the complementary experimental tests illustrated the visual behaviour of this specimen under increasing monotonic compression loading, a perfect bond within the ITZ has also been studied by using finite element analysis for comparison purposes. Finite element analysis was used to evaluate the degree of correctness and precision of the proposed ITZ model. This paper discusses the use of the cutoff bar in finite element modeling, representing the ITZ of a single aggregate (inclusion) in a mortar matrix. Experiments were conducted to investigate the influence of the ITZ model on the single inclusion specimen's strength. The model was tested for some inclusions that varied in dimension and shape. The effect of inclusion shape on the stress concentrations of the specimens was examined. The aim of this research work is to propose a simple yet accurate ITZ model to be used in the commercially available finite element software packages.

Effect of Microstructure on Hydrogen Induced Cracking Resistance of High Strength Low Alloy Steels

  • Koh, Seong Ung;Jung, Hwan Gyo;Kim, Kyoo Young
    • Corrosion Science and Technology
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    • v.6 no.4
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    • pp.164-169
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    • 2007
  • Hydrogen induced cracking (HIC) was studied phenomenologically and the effect of microstructure on HIC was discussed for the steels having two different levels of nonmetallic inclusions. Steels having different microstructures were produced by thermomechanically controlled processes (TMCP) from two different heats which had the different level of nonmetallic inclusions. Ferrite/pearlite (F/P), ferrite/acicular ferrite (F/AF), ferrite/bainite (F/B) were three representative microstructures for all tested steels. For the steels with higher level of inclusions, permissible inclusion level for HIC not to develop was different according to steelmicrostructure. On the contrary, HIC occurred also at the martensite/austenite (M/A) constituents regardless of steel microstructure when they accumulated to a certain degree. It was proved that M/A constituents were easily embrittled by hydrogen atoms. Steels having F/AF is resistant to HIC at a given actual service condition since they covers a wide range of diffusible hydrogen content without developing HIC.

A RELIABILITY-BASED CAPACITY RATING OF EXISTING BRIDGES BY INCORPORATING SYSTEM IDENTIFICATION (동특성 추정 기법과 신뢰성 해법에 의한 기설교량의 내하력 판정 방법)

  • Cho, Hyo-Nam;Yun, Chung-Bang
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 1990.04a
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    • pp.37-43
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    • 1990
  • This paper develops practical models and methods for the assessment of safety and rating of damaged and/or deteriorated bridges by incorporating a system identification technique for the explicit inclusion of the degree of deterioration or damage and of the actual bridge response. And, based on the proposed model, reliability-based rating methods are proposed as LRFR(Load and Resistance Factor Rating) and system reliability-index rating criteria. The proposed limit state model explicitly accounts for the degree of deterioration or damage in terms of the damage and response factors. The damage factor in the paper is proposed as the ratio of the current stiffness to the intact stiffness. Based on the observation and the results of applications to existing bridges, it may be concluded that the proposed rating models, which explicitly account for the uncertainties and the effects of degree of deterioration or damage based on the system identification technique, provide more realistic and consistent safety-assessment and capacity-rating.

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Screening and broadening effects on the mobilities for p-type Si and Ge (Screening 현상 및 broadening 현상이 p형 Si과 Ge의 이동도에 미치는 효과)

  • 전상국
    • Electrical & Electronic Materials
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    • v.10 no.6
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    • pp.581-588
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    • 1997
  • The ionization energy and degree of ionization for Si and Ge with boron doping are calculated. The hole mobilities are then calculated as a function of doping concentration using the relaxation time approximation. When the screening effect is taken into account, the reduction of ionization energy results in the increase of degree of ionization. As a result, the calculated Si mobility becomes closer to the experimental data, whereas the calculated Ge mobility is almost independent of the screening effect. The inclusion of the broadening effect in the mobility calculation overestimates the ionized impurity scattering. As compared with the experiment, the screening effect is not avoidable to calculate Si and Ge mobilities, and the broadening effect must accompany with the hopping process.

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Content Analysis of Newspapers' Travel News (신문의 관광보도 내용분석)

  • Park, Jowon
    • The Journal of the Korea Contents Association
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    • v.14 no.11
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    • pp.68-78
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    • 2014
  • Recently, media's attention to tourism is enhanced, and the proportion of tourism related content is increasing. Hence, the present study performed a content analysis of the travel news stories in major Korean newspapers to figure out the current state of travel journalism. A rotation sampling method was employed, and 53 days in 2013 were selected. Main coding categories were type, theme, and writer of the news stories and the degree of promotional information in the news stories. Differences among newspapers and the degree of inclusion of the promotional information according to news types and themes were analyzed. Analyses revealed the differences among newspapers and the degree of inclusion of promotional information was different according to the news types and themes. On the basis of the findings, problems of the travel journalism were identified, and possible measures to solve the problems were discussed.

Enzymatic Hydrolysis of Hydrophobic Triolein by Lipase in a Mone-phase Reaction System Containing Cyclodextrin; Reaction Characteristics

  • Lee, Yong-Hyun;Kim, Tae-Kwon;Shin, Hyun-Dong;Park, Dong-Chan
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.3 no.2
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    • pp.103-108
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    • 1998
  • A hydrophobic substrate triolein was hydrolyzed by lipase in a mono-phase reaction system containing cyclodextrin(CD) as emulsifier. The triolein was transformation to an emulsion-like state in the CD containing reaction system in contrast to the oil-droplet like state without CD due to the formation of an inclusion complex between the lipids and CDs. The hydyrolysis reaction increased substantially in the CD containing reaction system, and the optimum reaction conditions including the amount of lipase, ${\beta}$-CD concentration, and mixing ratio of triolein and ${\beta}$-CD, were determined. The performance of the enzyme reaction in a mono-phase reaction system was compared with that of a two-phase reaction system which used water immiscible hexane as the organic solvent. The role of a CD in the mono-phase reaction system was elucidated by comparing the degree of the inclusion complex formation with triolein and oleic acid, Km and Vmax values, and product inhibition by oleic aicd in aqueous and CD containing reaction systems. The resulting enhanced reaction seems to be caused by two phenomena; the increased accessibility of lipase to triolein and reduced product inhibition by oleic acid through the formation of an inclusion complex.

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Preparation of Microparticulate Itraconazole/Hydroxypropyl-$\beta$-cyclodextrin Inclusion Complexes Using a Supercritical Anti-Solvent [SAS] Process (초임계 역용매 공정을 이용한 Itraconazole/Hydroxypropyl-$\beta$-cyclodextrin 포접복합체 미세입자 제조)

  • 이상윤;김정규;김우식;유종훈;임교빈
    • KSBB Journal
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    • v.19 no.4
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    • pp.321-326
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    • 2004
  • Microparticles of an inclusion complex between itraconazole and 2-hydroxypropyl-${\beta}$-cyclodextrin (HP-${\beta}$-CD) were prepared using an environmentally-benign supercritical anti-solvent (SAS) process. In order to evaluate the degree of complexation, the thermal behavior of solid micro particulate complexes was investigated using differential scanning calorimetry. The experimental results obatined for the solubility and dissolution rate of the microparticulate inclusion complexes in a buffer solution of pH 1.2 showed that the complexation of itraconazole with HP-${\beta}$-CD results in a significant increase in the solubility and dissolution rate of itraconazole. For the microparticulate itraconazole/Hp-${\beta}$-CD inclusion complexes prepared by the SAS process, about 80% of itraconazole was found to dissolve in the buffer solution. Our experimental results confirmed that the SAS process is a promising method for the preparation of microparticles of water-insoluble drug/cyclodextrin inclusion complexes.

An Interval Approach to Fuzzy Pattern Recognition

  • Karbou, Fatiha;Karbou, Fatima;Karbou, M.
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 1998.06a
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    • pp.278-283
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    • 1998
  • The interval approach to the linguistic expression coding nears us to the human idea. Thus, what seems "weak" for a person can appear very weak for another person or for the same person in others circumstances. However, the utilization of intervals is not restrained to the cases of linguistic expression coding. Indeed, the interval can facilitate the solution of several problems.

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