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Serum Angiotensin-Converting Enzyme Levels in Coal Worker's Pneumoconiosis (탄광부 진폐증환자의 Angiotensin-Converting Enzyme 활성치)

  • Kim, Kyung-Dong;Choi, Myung-Sook;Lee, Chae-Hoon;Kim, Chung-Sook;Bae, Eun-Kyung
    • Journal of Yeungnam Medical Science
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    • v.6 no.1
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    • pp.109-119
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    • 1989
  • We measured fasting serum angiotensin -converting enzyme (SACE) in 100 healthy controls and 75 coal worker's pneumoconiosis (CWP) patients by a commercial kits($ACEcolor^{(R)}$, Fujirio Inc., Japan) and evaluated this manual method. The linear range extends to an activity of 80U/L. Precision on a commercial control serum (ACE control-$N^{(R)}$, Sigma Co.)with a mean value, of 9.47U/L yielded a within-run and between-run CVs are 5.6% (N=15) and 6.9% (N=14) respectively. SAVE in 75 CWP was $20.3{\pm}5.7U/L$ ($mean{\pm}s.d.$) ; higher than in healthy controls ($13.4{\pm}3.9U/L$, P<0.01). No correlation was found between SACE, sex, and age. The results suggest that the measurement of SACE and follow-up SACE in coal workers may be a useful diagnostic fools for CWP.

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Effects of Different Levels of Hermetia Illucens on Growth Performance and Nutrient Digestibility in Weaning Pigs (이유자돈 사료 내 동애등에(Hermetia illucens)의 첨가수준이 사양성적, 영양소소화율 및 경제성에 미치는 영향)

  • Choi, Yo-Han;Yoon, Se-Yeong;Jeon, Se-Min;Lee, Jae-Young;Oh, Seung-Min;Lee, Seung-Hyung;Kim, Jin-Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.9
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    • pp.255-261
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    • 2019
  • This trial was conducted to determine the optimal supplementation level of Hermetia illucens (HI) on the growth performance, the apparent total tract retention of nutrients and the economic efficiency in weaning pigs. A total of 192 weaned pigs ($Landrace{\times}Yorkshire{\times}Duroc$; $6.51{\pm}0.15kg$) were randomly allotted to 4 treatments and 6 replicates on the basis of their initial body weight. The dietary treatments included a corn-soybean meal based diet supplemented with 0, 1, 2 or 3% HI. There were no significantly effects between the treatments in phases I, II and overall. But average daily gain was significant and linearly increased when HI was added to the diet in the overall group. Although digestibility of dry matter (DM) was increased by adding HI, digestibility responses were not observed by supplying HI in phase I. Also, all the parameters of economic efficiency were not significantly different according to the level of HI. The results showed that HI had beneficial effects on growth performance and digestibility of dry matter. However, there were no effects on economic efficiency by using HI in weaning pig diets.

Research on ANIOS Disinfection Efficiency to Prevent Infection in Radiography Room (방사선촬영실 감염 방지를 위한 에니오설프의 소독효율 연구)

  • Jung, Woo-Chan;Ahn, Ki-Song;Yang, Eun-Ju;Kim, Young-Jae
    • Journal of the Korean Society of Radiology
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    • v.15 no.1
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    • pp.55-61
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    • 2021
  • In this study, microbes were collected before and after disinfection using ANIOS(ANIOSURF Premium NPC) and compared the areas where the radiological technologist and the patient frequently contacted the chest X-ray. From September 1st to September 7th, 2020. in P Hospital in Deagu, 4 region were collected in a 10×10 size using a sterile cotton swab of the transport medium, and before and after disinfection results were obtained through the colorimetric method. As a result, n the X-ray tube handle Proteus mirabilis, Staphylococcus epidermidis, Bacillus spp., Candida spp., and in the Chin region Proteus mirabilis, Enterococcu faecium, Pseudomonas aeruginosa, NTM, and in the Chest region Proteus mirabilis, Enterococcu faecium, Pseudomonas aeruginosa, and in the Palm region NTM, Candida spp. were detected, and 103 CFU(Colony Forming Unit) or more were measured. After disinfection, only X-ray tube handle was detect Bacillus spp. and more than 102 CFU was measured. Microorganisms found prior to disinfection can cause opportunistic infections, Experimental results showed that Aniosulf(0.25%) is more economical and disinfectant than ethanol(70-90%) and isopropyl alcohol(70-90%). However, further research is needed on the detection of Bacillus spp. resultingly this research is useful basic data of infection control in Radiography room and prevention secondary infections.

Appearance of Fish Species Based on the Weir's Density in the Four River Systems in Korea (국내 4대강 수계 하천의 보 밀도에 따른 어류 출현종 분석)

  • Moon, Woon Ki;Noh, Da Hye;Yoo, Jae Sang;Lim, O Young;Kim, Myoung Chul;Kim, Ji Hye;Lee, Jeong Min;Kim, Jai Ku
    • Ecology and Resilient Infrastructure
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    • v.9 no.2
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    • pp.93-99
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    • 2022
  • It was confirmed that the fish diversity decreased with increasing index of weir's density (IWD) in the four river systems. The IWD showed difference with watershed, it was high in the Nakdong River (NDR). Both two river systems of Gum River (GUR) and Yeongsan River (YSR) were similar, whereas relatively lower density observed in the Han River (HNR) system. A result of 2-Dimensional Kolmogorov-Smirnov (2-DKS) as a nonparametic test showed different threshold values affecting fish diversity with the river systems. The p-values based on Dmax, were significantly different at 0.05 level (except for YSR). The threshold values affecting fish diversity were also different with watershed. The values were 1.6/km of the HNR, 1.3/km of the NDR, and 2.3/km of the GUR, respectively. The fish diversity was decreased when IWD is over threshold values. The IWD of total 404 rivers (about 33%) among 1,217 surveyed in this study showed above threshold value. These rivers should be considered first for evaluating river continuity. The IWD and threshold value suggested in this study would be useful for selecting a stream priority for river connectivity study.

Impact of the Crossed-Structures Installed in Streams and Prediction of Fish Abundance in the Seomjin River System, Korea (하천에 설치된 횡구조물의 영향 및 섬진강 수계의 어류 풍부도 예측)

  • Moon, Woon Ki;Noh, Da Hye;Yoo, Jae Sang;Lim, O Young;Kim, Myoung Chul;Kim, Ji Hye;Lee, Jeong Min;Kim, Jai Ku
    • Ecology and Resilient Infrastructure
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    • v.9 no.2
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    • pp.100-106
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    • 2022
  • The relationships between river length and weir density versus fish species observed were analyzed for 210 local rivers in the Seomjin River system (SJR). A nonlinear exponential relationship between river length and number of fish species were observed. Model coefficient was 0.03 and coefficient of determinant (R2) was 0.59, meaning that about 59.0% of total variance was explained by river length variable. Predicted value by model and observed number of species showed a difference. About 110 local rivers (about 52.4%) showed lower value than predictive value. The average index of weir's density (IWD) in the SJR was about 2.7/km, which was significantly higher than that of other river basins. As a result of nonparametric 2-Kimensional Kolmogorov-Smirnov (2-DKS) analysis based on the IWD, the threshold value affecting fish diversity was about 2.5/km (Dmax=0.048, p<0.05). Above the threshold value, it means that the number of fish species would be decreased. In fact, the ratio of the expected species to the observed species was lowered to less than 70%, when the IWD is higher than the threshold value. To maintain aquatic ecological connectivity in future, it is necessary to manage IWD below the threshold value.

Study on the Evaluation of Thermal Damage According to the Manufacturing Conditions of Korean Paper (한지의 제조 조건에 따른 열 손상 평가 연구)

  • Kim, Ji Won;Park, Se Rin;Han, Ki Ok;Jeong, Seon Hwa
    • Journal of Conservation Science
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    • v.37 no.6
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    • pp.648-658
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    • 2021
  • In this study, we aimed to analyze the chemical changes that occur in Korean paper in an accelerated deterioration environment of 105℃. We selected the Korean paper produced with different types of cooking agents (plant lye, Na2CO3) and during different manufacturing seasons (winter, summer). The degree of deterioration of the Korean paper was confirmed by measuring the brightness, yellowness, and pH level, and the degree of change in each vibrational region of cellulose as deterioration progressed through infrared (FT-IR) spectroscopy. The FT-IR analysis showed that, as deterioration progressed, the absorbance of the amorphous region in cellulose decreased, whereas the absorbance of the crystalline region slightly increased. X-Ray diffraction (XRD) analysis and Raman spectroscopy were performed to verify the changes in the crystalline and amorphous regions in cellulose indicated by the FT-IR results. Furthermore, the crystallinity index (CI) was calculated; it showed a slight increase after deterioration; therefore, CI was confirmed to follow the same trend as that observed for absorbance in the FT-IR results. In addition, as a result of Raman spectroscopic analysis, the degree of decomposition of the amorphous region in the cellulose under the manufacturing conditions was confirmed by the fluorescence measured after the deterioration.

Synthesis of Linear 1,2-Alkylaminopropanediols as Preservatives and Antimicrobial Activity (보존제로서 선형 1,2-알킬아미노프로판디올의 합성과 항균활성)

  • Cha, Kyung-On;Kwak, Sang-Woon;Jeong, Kook-In;Kim, Young-Ho
    • Applied Chemistry for Engineering
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    • v.33 no.4
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    • pp.394-401
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    • 2022
  • The synthesis of 1,2-alkylaminopropanediols (1,2-AAPs) was designed to improve the hydrophilicity of linear 1,2-alkanediols having 10, 12, 14, and 16 carbon atoms in the alkyl chain. 1,2-AAPs were synthesized by reacting 3-monochloro-1,2-propanediol (3-MCPD) with linear alkylamines having 10, 12, 14 or 16 carbon atoms in an ethanol solvent at 40℃ for 2 h. The yield and purity of four types of 1,2-AAPs synthesized were found to be in the range of 51-58% and 85-99%, respectively. The amine salts of four types of 1,2-AAPs were prepared from a purified paste or solid compound by adding an acidic solution (HCl) to pH 7, and then their solubilities and antibacterial effects were tested. 1,2-decylaminopropanediol, 1,2-dodecylaminopropanediol, and 1,2-tetradecylaminopropanediol were all dissolved in water at concentrations of 100%, 50%, and 0.1%, respectively, however 1,2-hexadecylaminopropanediol was not. The antibacterial effect was improved as the length of the alkyl chain increased. As a result of confirming the preservative effect of the lotion (cosmetic formulation) applied with 1,2-AAP for application, it showed very strong antibacterial activity at low concentrations ranging from 0.005% to 0.2%.

Comparison of retentive force and wear pattern of Locator® and ADD-TOC attachments combined with CAD-CAM milled bar

  • Chae, Sung-Ki;Cho, Won-Tak;Choi, Jae-Won;Bae, Eun-Bin;Bae, Ji-Hyeon;Bae, Gang-Ho;Huh, Jung-Bo
    • The Journal of Advanced Prosthodontics
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    • v.14 no.1
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    • pp.12-21
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    • 2022
  • PURPOSE. The purpose of this study was to investigate changes in retention and wear pattern of Locator® and ADD-TOC attachments on a digital milled bar by performing chewing simulation and repeated insertion/removal of prostheses in fully edentulous models. MATERIALS AND METHODS. Locator (Locator®; Zest Anchors Inc., Escondido, CA, USA) was selected as the control group and ADD-TOC (ADD-TOC; PNUAdd Co., Ltd., Busan, Republic of Korea) as the experimental group. A CAD-CAM milled bar was mounted on a master model and 3 threaded holes for connecting a bar attachment was formed using a tap. Locator and ADD-TOC attachments were then attached to the milled bar. Simulated mastication and repeated insertion/removal were performed over 400,000 cyclic loadings and 1,080 insertions/removals, respectively. Wear patterns on deformed attachment were investigated by field emission scanning electron microscopy. RESULTS. For the ADD-TOC attachments, chewing simulation and repeated insertion/removal resulted in a mean initial retentive force of 24.43 ± 4.89 N, which were significantly lower than that of the Locator attachment, 34.33 ± 8.25 N (P < .05). Amounts of retention loss relative to baseline for the Locator and ADD-TOC attachments were 21.74 ± 7.07 and 8.98 ± 5.76 N (P < .05). CONCLUSION. CAD-CAM milled bar with the ADD-TOC attachment had a lower initial retentive force than the Locator attachment. However, the ADD-TOC attachment might be suitable for long-term use as it showed less deformation and had a higher retentive force after simulated mastication and insertion/removal repetitions.

A Case of Propionic Acidemia Presenting with Dilated Cardiomyopathy (확장성 심근병증으로 발현된 프로피온산혈증 1례)

  • Son, Jisoo;Choi, Yoon-Ha;Seo, Go Hun;Kang, Minji;Lee, Beom Hee
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.21 no.1
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    • pp.22-27
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    • 2021
  • Propionic acidemia (PA) is an inherited autosomal recessive disorder, due to the deficiency of propionyl-CoA carboxylase (PCC). PCC is the enzyme which catalyzes the conversion of propionyl-CoA to D-methylmalonyl-CoA, and it is critical for the metabolism of amino acids, odd-chain fatty acids, and side chains of cholesterol. The clinical manifestations present mostly at the neonatal period with life-threatening metabolic acidosis and hyperammonemia. Here, we described a case of a 16-year-old Korean boy with late-onset PA who presented with embolic cerebral infarction due to dilated cardiomyopathy (DCMP) with left ventricular noncompaction. And he has family history of sudden cardiac death, so we performed metabolic screening and genetic tests. Elevated levels of 3-hydroxypropionic acid, methylcitric acid and propionylglycerine were detected in urine. Plasma acylcarnitine profile showed elevated propionylcarnitine (C3). Diagnosis of PA was confirmed by genetic analysis, which revealed compound heterozygous mutations, c.[1151T>G] (p.[Phe384Cys]) and c.[1228C>T] (p.[Arg410Trp]) in PCCB gene. His heart function is in improving state and the results of biochemical analysis are stable with heart failure medication and metabolic managements. We present a case of patient without episodes of metabolic decompensation who manifests DCMP as the first symptom of PA.

Planar microchip-based lactate biosensor (평면 소자형 락테이트 바이오센서)

  • Ha, Jeonghan;Huh, Hwang;Kang, Tae Young;Lee, Yong Seok;Yoon, Soon Ho;Shin, Jungwon;Nam, Hakhyun;Cha, Geun Sig
    • Analytical Science and Technology
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    • v.19 no.6
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    • pp.482-489
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    • 2006
  • Two electrode-based lactate biosensor was prepared by immobilizing lactate oxidase (LOD) obtained from pediococcus species in a poly(vinyl alcohol). Hydrogen peroxide ($H_2O_2$) produced by the reaction of lactate and LOD was detected on the Pt-black that was electrochemically deposited on the Au electrode. Sensors fabricated with Pt-black deposited Au electrode provided a high current of $H_2O_2$ oxidation at a substantially lowered applied potential (+300 mV vs. Ag/AgCl), resulting in reduced interferences from easily oxidizable species such as ascorbic acid, acetaminophen, and uric acid. An outer membrane is formulated by adjusting water uptake of hydrophilic polyurethane (HPU). The sensor performance was evaluated in vitro with both flow-through arrangement and static mode. The sensor showed a linear range from 0.1 mM to about 9.0 mM in 0.05 M phosphate buffer (pH 7.6) containing 0.05 M NaCl. Storing the sensors prepared in this work at $4^{\circ}C$ buffer solution while not in use, they provided same electrochemical performance for more than 25 days.