• 제목/요약/키워드: In-situ diagnosis

검색결과 153건 처리시간 0.023초

치성낭종으로부터 유래된 편평상피세포암종 (SQUAMOUS CELL CARCINOMA ARISING FROM RESIDUAL ODONTOGENIC CYST;Report of a Case & Review of Literatures)

  • 김용각;박형국;권혁진;현재훈
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제19권2호
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    • pp.209-214
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    • 1997
  • Odontogenic cysts are relatively common pathologic lesions found in the oral and perioral structures, but the case of squamous cell carcinoma arising from those cysts are very uncommon. After first reported of that case in 1889 by Herman, Schwimmer collected 56 cases of previously reported squamous cell carcinoma arising in residual odontogenic cyst during about past one century. More than 60% of cases of carcinoma developing in odontogenic cysts arising in inflammatory periapical or residual cyst, and these tumors are usually well-differentiated with relatively good prognosis, and often are diagnosed as benign lesion in radiographic or clinical examination, therefore definitive diagnosis must be made by histologic examintation. We report a case and review the literatures, in our case, 78-year old woman were clinically and radiographically diagnosed as residual odontogenic cyst. But in histologic examination after enucleation of lesion, mass of squamous cell carinoma were observed, but in other area, typical cyst wall and lining epithelium were observed. And in some area, carcinoma in situ and invading squamous cell carcinoma into the lining epithelium were also observed.

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Light and Electron Microscopy Studies Elucidating Mechanisms of Tomato Leaf Infection by Pseudocercospora fuligena

  • Zelalem Mersha;Girma Birru;Bernhard Hau
    • The Plant Pathology Journal
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    • 제39권2호
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    • pp.181-190
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    • 2023
  • The fungal pathogen Pseudocercospora fuligena, known to affect tomatoes in the tropics and subtropics, has been reported from temperate climates including the United States and Turkey in recent years. In this study, an isolate from fresh tomatoes and the disease it causes were characterized and infection mechanisms investigated. Macroscopically, both sides of tomato leaves show indistinct effuse patches but prolific production of fuliginous lesions is conspicuous on the abaxial side first but also on the adaxial side later on as infection progressed. Microscopically, fascicles of conidiophores (11-128 ㎛ × 3.5-9 ㎛) arising from stromata and conidia with up to 12 septations were observed. Molecular characterization of the isolate revealed high homology (99.8%) to other P. fuligena isolated from tomatoes in Turkey. Out of the 10 media tested, P. fuligena grew significantly well and sporulated better on unsealed tomato oatmeal agar and carrot leaf decoction agar, both supplemented with CaCO3. Direct transfer of conidia from profusely sporulating lesions was the easiest and quickest method of isolation for in-vitro studies. Light and scanning electron microscopy on cleared and intact tomato leaves further confirmed stomatal penetration and egress as well as prevalence of primary and secondary infection hyphae. In situ, blocked stomatal aperture areas of 154, 401, and 2,043 ㎛2 were recorded at 7, 12, and 17 days after inoculation, respectively. With the recent expanded horizon of the pathosystem and its consequential impact, such studies will be useful for a proper diagnosis, identification and management of the disease on tomato worldwide.

음향방출법을 이용한 굽힘피로 손상된 소켓용접배관의 진단 및 감시 (Diagnosis and Monitoring of Socket Welded Pipe Damaged by Bending Fatigue Using Acoustic Emission Technique)

  • 김정석;오세웅;박익근
    • 비파괴검사학회지
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    • 제28권4호
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    • pp.323-330
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    • 2008
  • 소구경 배관 소켓 용접부의 고주기 피로특성윽 평가하고 피로 균열의 발생을 음향방출법을 이용하여 실시간 모니터링 하였다. 스테인리스 316L강 시험편은 가스텅스텐아크용접 공정으로 루트부에 결함이 없는 시험편과 용입불량 결함이 있는 시험편으로 준비하였다. 피로파단은 고응력 일때는 토우부, 상대적으로 저응력일 때는 루트부에서 일어났다. 피로시험동안 음향방출 카운트가 급격히 증가하는 시점을 균열의 발생 싸이클 ($N_i$)로 정의하였고 방사선투과법과 전자현미경을 이용하여 피로균열 생성 싸이클 전과 후에서 균열을 확인하였다. 소켓용접배관의 굽힘피로 손상 진단 및 감시를 위해 균열의 존재와 파괴모드 그리고 균열의 발생 싸이클에 관한 연구를 수행하였다.

IC 센서를 이용한 고속철도차량 구동장치의 무선 온도 모니터링 시스템 (Wireless Temperature Monitoring of Driving Gear Unit in High Speed Train Using IC Sensor)

  • 권석진;서정원;이동형;황지성
    • 한국정밀공학회지
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    • 제30권7호
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    • pp.673-678
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    • 2013
  • Driving gear units can be affected by various problems, including those associated with external or internal defects in the bearing, problems with the lubricant oil, high-loading of the railway, and frequent impacts generated by rail joints. Temperature monitoring is a basic method in diagnosing abnormal conditions in the reduction gear and other components. This paper describes a new wireless monitoring system for the temperature diagnosis of abnormal conditions of the reduction gear. Integrated circuit (IC)-type temperature sensors were installed in the reduction gear box of a high-speed railway car. The temperature data from the reduction gear were acquired and analyzed in situ during high-speed rail operation. Analysis of these data was used to alert the driver and/or maintenance personnel when problems occurred.

Stress evaluation of tubular structures using torsional guided wave mixing

  • Ching-Tai, Ng;Carman, Yeung;Tingyuan, Yin;Liujie, Chen
    • Smart Structures and Systems
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    • 제30권6호
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    • pp.639-648
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    • 2022
  • This study aims at numerically and experimentally investigating torsional guided wave mixing with weak material nonlinearity under acoustoelastic effect in tubular structures. The acoustoelastic effect on single central frequency guided wave propagation in structures has been well-established. However, the acoustoelastic on guided wave mixing has not been fully explored. This study employs a three-dimensional (3D) finite element (FE) model to simulate the effect of stress on guided wave mixing in tubular structures. The nonlinear strain energy function and theory of incremental deformation are implemented in the 3D FE model to simulate the guided wave mixing with weak material nonlinearity under acoustoelastic effect. Experiments are carried out to measure the nonlinear features, such as combinational harmonics and second harmonics in related to different levels of applied stresses. The experimental results are compared with the 3D FE simulation. The results show that the generation combinational harmonic at sum frequency provides valuable stress information for tubular structures, and also useful for damage diagnosis. The findings of this study provide physical insights into the effect of applied stresses on the combinational harmonic generation due to wave mixing. The results are important for applying the guided wave mixing for in-situ monitoring of structures, which are subjected to different levels of loadings under operational condition.

Development of Nested Polymerase Chain Reaction for the Detection of Mycoplasma hyopneumoniae in Formalin-fixed Paraffin-embedded Lung Tissues

  • Lim, Jung-eun;Ha, Seung-kwon;Chae, Chan-hee
    • 한국수의병리학회:학술대회논문집
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    • 한국수의병리학회 2003년도 추계학술대회초록집
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    • pp.29-29
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    • 2003
  • Mycoplasma hyopneumoniae is among the most prevalent and important infectious agents associated with porcine respiratory disease complex. The airway dagame caused by M. hyopneumoniae adversely affect the pulmonary host defense mechanisms and may lead to secondary bacterial infections. Culture is considered to be the "gold standard" for diagnosis but this is a very slow and labor-intensive procedure. Isolation of M. hyopneumoniae is complicated by its fastidious nature and extremely slow growth. Thirty days of incubation may be necessary to detect the organism in primary broth cultures. The purposes of the study were (ⅰ) to develop nested PCR for the detection of M. hyopneumoniae for the detection of M. hyopneumoniae DNA in the formalin-fixed, paraffin-embedded lung tissues from experimentally and naturally infected pigs and (ⅱ) to compare the utility of nested PCR with in situ hybridization. (omitted)

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Incipient Fault Detection of Reactive Ion Etching Process

  • Hong, Sang-Jeen;Park, Jae-Hyun;Han, Seung-Soo
    • Transactions on Electrical and Electronic Materials
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    • 제6권6호
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    • pp.262-271
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    • 2005
  • In order to achieve timely and accurate fault detection of plasma etching process, neural network based time series modeling has been applied to reactive ion etching (RIE) using two different in-situ plasma-monitoring sensors called optical emission spectroscopy (OES) and residual gas analyzer (RGA). Four different subsystems of RIE (such as RF power, chamber pressure, and two gas flows) were considered as potential sources of fault, and multiple degrees of faults were tested. OES and RGA data were simultaneously collected while the etching of benzocyclobutene (BCB) in a $SF_6/O_2$ plasma was taking place. To simulate established TSNNs as incipient fault detectors, each TSNN was trained to learn the parameters at t, t+T, ... , and t+4T. This prediction scheme could effectively compensate run-time-delay (RTD) caused by data preprocessing and computation. Satisfying results are presented in this paper, and it turned out that OES is more sensitive to RF power and RGA is to chamber pressure and gas flows. Therefore, the combination of these two sensors is recommended for better fault detection, and they show a potential to the applications of not only incipient fault detection but also incipient real-time diagnosis.

Nonsyndromic Multiple Basal Cell Carcinomas

  • Kim, Dong Hwi;Ko, Hyo Sun;Jun, Young Joon
    • 대한두개안면성형외과학회지
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    • 제18권3호
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    • pp.191-196
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    • 2017
  • Basal cell carcinoma (BCC) comprising several lesions is not uncommon, but nonsyndromic multiple BCCs with parotid invasion are rare entities. We present two cases of multiple sporadic, nonsyndromic BCCs, and one of these cases is a unique case of parotid invasion associated purely with actinic keratosis. In Case 1, a 79-year-old female presented with multiple skin lesions on the face and left hand. All lesions were completely removed by surgery. The pathologic results showed lesions consistent with BCC and some lesions consistent with actinic keratosis. After 8 months, the patient presented with skin lesions in bilateral temporal areas and left cheek area. Surgical excision of the lesions was performed, and the biopsy results were squamous cell carcinoma in situ and actinic keratosis. In Case 2, a 43-year-old woman presented with multiple skin lesions on the face, scalp, right chest, abdomen and right leg. All lesions were completely removed by surgery. Pathologic evaluation confirmed the diagnosis of BCC. BCC is rarely metastatic, but it can lead to severe disfiguration or destruction. It is important to diagnose and treat BCC at an early stage.

FISH를 이용한 다운증후군과 에드워드증후군의 신속한 산전확인 : 309예의 임상적 고찰 (Rapid prenatal diagnosis of Down syndrome and Edward syndrome by fluorescence In situ hybridization : Clinical experience with 309 cases)

  • 강진희;이숙환;박상희;박지현;김지연;한원보;김인현;박상원;장진범;이경진;박희진;전혜선;이경주;신중식;차동현
    • Journal of Genetic Medicine
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    • 제4권1호
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    • pp.64-71
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    • 2007
  • 목 적 : 다운증후군과 에드워드증후군의 빠른 진단에 있어 FISH 검사의 임상적 유용성과 한계성을 보고하고자 한다. 방 법 : 유전질환이 의심되는 고위험임신 309예에서 양수 검사를 통해 미배양 양수세포에서 18번과 21번 염색체의 probes를 이용한 FISH 검사를 시행하고 이들의 결과를 염색체 핵형분석 결과와 비교하였다. 결 과 : 평균연령은 34.18세, 평균임신주수는 18주(126.12 일)의 309예에서 FISH 검사는 모두 성공하였다. 각각 1예씩의 다운증후군과 에드워드증후군이 FISH로 신속한 진단이 가능했으며 이들은 염색체 핵형 검사에서 확인하였다. 그러나 18번과 21번 이외의 염색체의 이수성과 구조적 이상은 발견하지 못했는데 모두 12예(3.9%)로 상당부분을 차지했다. 앞으로 산전 선별검사에 있어 FISH검사과정의 자동화 기계화로 더 시간을 단축하고 가격을 낮추는 방안이 계속 개발되어야 할 것이다.

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Breast Screening and Breast Cancer Survival in Aboriginal and Torres Strait Islander Women of Australia

  • Roder, David;Webster, Fleur;Zorbas, Helen;Sinclair, Sue
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권1호
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    • pp.147-155
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    • 2012
  • Aboriginal and Torres Strait Islander people comprise about 2.5% of the Australian population. Cancer registry data indicate that their breast cancer survivals are lower than for other women but the completeness and accuracy of Indigenous descriptors on registries are uncertain. We followed women receiving mammography screening in BreastScreen to determine differences in screening experiences and survivals from breast cancer by Aboriginal and Torres Strait Islander status, as recorded by BreastScreen. This status is self-reported and used in BreastScreen accreditation, and is considered to be more accurate. The study included breast cancers diagnosed during the period of screening and after leaving the screening program. Design: Least square regression models were used to compare screening experiences and outcomes adjusted for age, geographic remoteness, socio-economic disadvantage, screening period and round during 1996-2005. Survival of breast cancer patients from all causes and from breast cancer specifically was compared for the 1991-2006 diagnostic period using linked cancer-registry data. Cox proportional hazards regression was used to adjust for socio-demographic differences, screening period, and where available, tumour size, nodal status and proximity of diagnosis to time of screen. Results: After adjustment for socio-demographic differences and screening period, Aboriginal and Torres Strait Islander women participated less frequently than other women in screening and re-screening although this difference appeared to be diminishing; were less likely to attend post-screening assessment within the recommended 28 days if recalled for assessment; had an elevated ductal carcinoma in situ but not invasive cancer detection rate; had larger breast cancers; and were more likely than other women to be treated by mastectomy than complete local excision. Linked cancer registry data indicated that five-year year survivals of breast cancer cases from all causes of death were 81% for Aboriginal and Torres Strait Islander women, compared with 90% for other women, and that the former had larger breast cancers that were more likely to have nodal spread at diagnosis. After adjusting for socio-demographic factors, tumour size, nodal spread and time from last screen to diagnosis, Aboriginal and Torres Strait Islander women had approximately twice the risk of death from breast cancer as other women. Conclusions: Aboriginal and Torres Strait Islander women have less favourable screening experiences and those diagnosed with breast cancer (either during the screening period or after leaving the screening program) have lower survivals that persist after adjustment for socio-demographic differences, tumour size and nodal status.