• The Journal of Korean Physical Therapy
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• 제24권5호
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• pp.355-361
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• 2012

Purpose: The purpose of this study was to evaluate the effectiveness of pulmonary rehabilitation on lung function and fatigue in persons with chronic obstructive pulmonary disease (COPD). Methods: Thirty one persons with COPD participated in this study. Four groups were allocated as follows: experimental group 1 (under 10 years of the post-disease period), control group 1 (under 10 years of the post-disease period), experimental group 2 (over 10 years of the post-disease period), and control group 2 (over 10 years of the post-disease period). Results: Forced expired volume in one second (FEV1) % pred and lactic acid showed improvement in experimental group 1 and experimental group 2 after training. Control group 1 and control group 2 did not show improvement of FEV1% pred and lactic acid after training. However, FEV1% pred and lactic acid in experimental group 1 were not significantly different, compared with the experimental group. Conclusion: Results of our study suggest that implementation of a pulmonary rehabilitation program resulted in improvement of lung function and fatigue in persons with COPD not related to the post-disease period.

• 말소리와 음성과학
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• 제1권2호
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• pp.37-42
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• 2009

The purpose of the present study was to determine the effect of the management program known as vocal function exercise (VFE) on voice quality. Typical VFE was modified and applied to patients with vocal nodules by controlling intensity of voice and relieving the vocal fold to solve hyperfunctional problems in VFE. Eight female subjects aged between 28 and 54 who had been diagnosed with vocal nodules took part in the study. The patients performed VFEs once a week for eight weeks. Vocal function exercises consist of voice hygiene, respiratory training, phonation training, and glide training. The subjects' voices were analyzed pre and post therapy on the aspects of acoustics, maximum phonation time (MPT), GRBAS, and voice handicap index (VHI). As a result, it was found that fundamental frequency ($F_o$) was significant increased, shimmer decreased remarkably and that noise to harmonic ratio (NHR) lowered obviously in the acoustic parameter. In addition, MPT was increased significantly. The scale of GRBAS indicated significant improvement in grade, roughness, and strained voice. VHI indicated significant improvement in an emotional part. In conclusion, VFE was effective in improving voice quality for patients with vocal nodules.

• 대한한방내과학회지
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• 제26권1호
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• pp.1-11
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• 2005

Backgrounds : Gamichungsangboha-tang extract has been known to improve pulmonary functions and quality of life within four weeks of treatment. Cessation of treatment causes recurrence of symptoms and regression of pulmonary function and poorer quality of life. Long-term herbal therapy is difficult to maintain due to economic burden and other reasons. AF-365 is made with reduced dosage of Gamichungsangboha-tang extract. This study was designed to evaluate the effectiveness of AF-365 for maintenance therapy. Materials and Methods : The subjects consisted of 27 patients with asthma who had beed treated with AF-365 for four weeks. First, patients were treated with Gamichungsangboha-tang extract for four weeks. Second patients stopped herbal medicine for four weeks and after that they took AF-365. Pulmonary function test(PFT) was checked before and after four weeks of treatment. Quality of Life Questionnaire for Adult Korean Asthmatics(QLQAKA) was checked every two weeks from the beginning. The effects of AF-365 were analysed throughout the last four weeks. Results : Treatment of AF-365 for four weeks resulted in significant increase in PEFR%, QLQAKA. The QLQAKA of the step3, step4 group classified by Global initiative for asthma(GINA) showed significant improvement, and the QLQAKA of the step2 group showed no significant difference. In step3 group, PEFR% increased significantly. Conclusions : This study supports a role for AF-365 in maintenance of pulmonary function and quality of life, especially in persistent symptomatic asthmatics.

• 문화기술의 융합
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• 제7권4호
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• pp.203-210
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• 2021

본 연구는 노력성 호흡 운동 중심의 촛불끄기 호흡훈련이 성인의 몸통 근력 강화를 의미하는 호흡 능력 향상에 어떤 유의한 효과가 있는지를 알아보기 위하여 실시하였다. 4주간의 촛불끄기 훈련을 통해 실험 전-후의 노력성폐활량(FVC)은 통계학적으로 유의하게 증가하였다(p<.05). 4주간의 촛불 끄기 훈련을 통해 실험 전-후의 1초간 노력성 날숨량(FEV1)의 변화는 통계학적으로 유의한 차이를 보이지 않았다(p>.05). 4주간의 촛불 끄기 훈련을 통해 실험 전-후의 최대날숨유속(PEF)은 유의하게 증가하였다(p<.05). 본 연구는 건강한 성인을 대상으로 노력성 호흡 운동 중심의 촛불끄기 호흡운동을 실시하여 성인의 몸통 근력 강화를 의미하는 노력성 폐활량(FVC), 1초간 노력성 날숨량(FEV1), 최대날숨유속(PEF) 등의 노력성 호흡훈련과 허파기능의 관계에 대해 조사하여 유의한 결과를 얻었다. 앞으로 물리치료가 꼭 필요한 중증 호흡기계 질환자를 대상으로 하는 연구가 진행되어야 할 것으로 사료된다.

• 대한간호학회지
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• 제33권5호
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• pp.570-579
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• 2003

Purpose: The purpose of this study is to exam the effects of a short-term pulmonary program on lung function, exercise tolerance, and quality of life in chronic lung patients. Method: Randomized controlled pre-post test design was used. The outcome measures were forced expiratory volume in one second (FEV1, % predicted), 6 min walking distance (6MWD), Borg score after 6MWD, and Chronic Respiratory Disease Questionnaire (CRDQ). Experimental group performed the 4-week home-based pulmonary rehabilitation program composed of inspiratory muscle training, upper and lower extremity exercise, relaxation, and telephone visit. Patients in control group were only given education about self-management strategies. Thirty four patients with moderate-to-severe respiratory impairment were recruited, and 28 patients (19 in experiments, 15 in control) completed the study. Result: Significant improvements in lung function, exercise tolerance, and health related quality of life were found only in the experiment group. Conclusion: This study yielded evidence for the potential and beneficial effects of home-based pulmonary rehabilitation program in patients with moderate to severe chronic lung disease. The program could be adequately utilized for improvement of health related quality of life in chronic lung patients.

• Tuberculosis and Respiratory Diseases
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• 제73권1호
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• pp.1-10
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• 2012

Care of patients with sepsis has improved over the last decade. However, in the recent two years, there was no significant progress in the development of a new drug for critically ill patients. In January 2011, it was announced that the worldwide phase 3 randomized trial of a novel anti-Toll-like receptor-4 compound, eritoran tetrasodium, had failed to demonstrate an improvement in the mortality of patients with severe sepsis. In October 2011, Xigris (drotrecogin alfa, a recombinant activated protein C) was withdrawn from the market following the failure of its worldwide trial that had attempted to demonstrate improved outcome. These announcements were disappointing. The recent failure of 2 promising drugs to further reduce mortality suggests that new approaches are needed. A study was published showing that sepsis can be associated to a state of immunosuppression and loss of immune function in human. However, the timing, incidence, and nature of the immunosuppression remain poorly characterized, especially in humans. This emphasizes the need for a better understanding of sepsis as well as new therapeutic strategies. Many clinical experiences of the extracorporeal membrane oxygenator (ECMO) treatment for adult acute respiratory distress syndrome (ARDS) patients, which is caused by the H1N1 influenza A virus, were reported. The use of ECMO in severe respiratory failure, particularly in the treatment of adult ARDS, is occurring more commonly.

• Journal of Chest Surgery
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• 제17권3호
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• pp.409-417
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• 1984

In the early days of open heart surgery, acute respiratory failure following extracorporeal circulation was a significant deterrent to an uncomplicated recovery. Although a marked improvement in prevention and treatment of postoperative respiratory failure has been achieved, the problem has not been completely eliminated and continues to be a causative factor in morbidity and mortality Fates following open heart surgery. We have attempted to evaluate postoperative respiratory failure in patients undergoing cardiac operation with the aid of extracorporeal circulation. Our series comprised 92 patients who underwent elective open heart surgery at the Department of Thoracic and Cariodvascular Surgery, School of Medicine, Kyungpook National University, from January, 1980 to December, 1982. In our study, the overall incidence of acute respiratory failure following open heart surgery was 18.8 percent. The duration of extracorporeal circulation in a series of 18 patients who developed postoperative respiratory failure [Group B] was longer in the mean value [120.3 minutes] than the uncomplicated 74 patients [Group A] [85.8 minutes]. The duration of artificial ventilation after open heart surgery in Group A averaged 13.4 hours as contrasted with 76.5 hours in Group B. In Group B, the inspired oxygen concentration [FiO2] in artificial ventilation was continued in the higher level than Group A until 18 hours after operation. Upon pulmonary function test performed pre-and postoperatively, residual volume[RV], RV/TLC and FEV 1.0/FVC were remained essentially unchanged following extracorporeal circulation, whereas forced vital capacity [FVC], FEV 1.0 and FEF 25-75% were significantly decreased in the early postoperative days. The incidence of acute respiratory failure was significantly higher in a series of patients who developed postoperative complications, such as re- exploration due to massive bleeding, low cardiac output, acute renal failure and arrhythmias. A total of 9 patients died, giving an overall mortality was 33.3 percent whereas the mortality was only 1.1 percent for patients without respiratory failure.

• 대한물리의학회지
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• 제10권1호
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• pp.15-21
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• 2015

PURPOSE: This study compared the effects of chest expansion resistance exercise (CERE) and breathing retraining (BRT) on stroke patients' chest expansion and maximal inspiratory pressure(MIP), thereby intending to present an effective intervention method for enhancing their respiratory functions. METHODS: The subjects were 30 stroke patients and randomly and equally assigned to a CERE group (10), a BRT group (10), and a control group (10). The intervention was applied to each group five times per week, 30 minutes per each time, for six weeks. A tapeline was used to measure upper and lower chest expansion and MIP prior to and after the intervention and the results were compared. RESULTS: After the intervention, the upper and lower chest expansion was considerable in the CERE group (p<.01), significant in the BRT group (p<.05) but was not significant in the control group (p>.05). According to the post-hoc test result, the upper and lower chest of the CERE group and the BRT group significantly expanded compared to that of the control group (p<.05) and the upper and lower chest of the CERE group statistically significantly expanded relative to that of the BRT group (p<.05). According to the MIP evaluation result, the CERE group saw considerable improvement (p<.01) and the BRT group underwent significant changes (p<.05), but there were no significant changes in the control group (p>.05). The post-hoc test result was that the CERE group and the BRT group saw significant improvement compared to the control group (p<.05) and the CERE group experienced statistically significant enhancement relative to the BRT group (p<.05). CONCLUSION: As an intervention for respiratory function improvement, CERE is considered effective for strengthening respiratory muscles and promoting chest expansion through manual resistance by a therapist.

• 동의생리병리학회지
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• 제21권4호
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• pp.1045-1050
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• 2007

This study was conducted to help oriental medical prevention program policy for improvement of public health in a local community. We have researched respiratory diseases and demands for oriental medical cold preventing therapy of some residents in Chung-Buk. We have conducted individually face-to-face interviews through standardized questionnaires to 141 residents of two towns (76 in Haeng-jung, 65 in Gu-mi) under the jurisdiction of Chung-won Public Health Center. The senior aged over 65 was 53.9%, which was a little more than the average senior age. The rate which could be diagnosed as a disorder of lung function was 2.97% by Lung Function Test. The participants diagnosed as Asthma accounted for 17.9% by Symptom Based Easy Asthma Diagnosis of Easy Asthma Management(EAM). The participants who had intentions of participating in oriental medical cold preventing therapy accounted for 58.6%. And among the oriental medical cold preventing therapy the preference for acupuncture and moxibustion was 77.1 %, which was much higher than any other thing. It is thought that people still have little understanding about the oriental medical cold preventing therapy. Therefore it is considered that the Korean government should try to establish well-organized cold preventing system on the basis of Oriental Medical theory for a local community.

• Tuberculosis and Respiratory Diseases
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• 제65권5호
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• pp.410-415
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• 2008

폐쇄성 세기관지염은 골수 이식 후 폐에 발생하는 합병증이다. 현재 스테로이드와 면역 억제제를 투여하여 적극적인 치료를 하더라도 폐기능의 호전을 보이는 경우는 일부에 불과하다. 저자들은 기존의 치료에도 불구하고 호전을 보이지 않은 골수 이식 후 발생한 폐쇄성 세기관지염 환자에서 macrolide계 항생제인 azithromycin을 1년간 경구 투여하여 폐기능이 호전됨을 경험하였기에 문헌고찰과 함께 보고하는 바이다.