• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5557-5563
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• 2015

Background: Cholelithiasis is associated in 54%-98% of patients with carcinoma of the gallbladder, and a high incidence among females suggests a role of female hormones in the etiology of the disease. Cytochrome $P450C17{\alpha}$ (CYP-17) is a key enzyme involved in estrogen metabolism and polymorphisms in CYP-17 are associated with altered serum levels of estrogens. Thus, we investigated whether the CYP-17 MspA1 gene polymorphism might impact on risk of gall bladder cancers or gallstones, as well as to determine if this gene polymorphism might be linked with estrogen serum levels and lipid profile among the North Indian gall bladder cancer or gallstone patients. Materials and Methods: CYP-17 gene polymorphisms (MspA1) were genotyped with PCR-RFLP in cancer patients (n=96), stone patients (n=102), cancer + stone patients (n=52) and age/sex matched control subjects (n= 256). Lipid profile was estimated using a commercial kit and serum estrogen was measured using ELISA. Results: The majority of the patients in all groups were females. The lipid profile and estrogen level were significantly higher among the study as compared to control groups. The frequency of mutant allele A2 of CYP17 MspA1 gene polymorphism was higher among cancer (OR=5.13, 95% CI+3.10-8.51, p=0.0001), stone (OR=5.69, 95%CI=3.46-9.37, p=0.0001) and cancer + stone (OR=3.54, 95%CI=1.90-6.60, p=0.0001) when compared with the control group. However there was no significant association between genotypes of CYP17 MspA1 gene polymorphism and circulating serum level of estrogen and lipid profile. Conclusions: A higher frequency of mutant genotype A1A2 as well as mutant allele A2 of CYP-17 gene polymorphism is significantly associated with risk of gallbladder cancer and stones. Elevated levels of estrogen and an altered lipid profile can be used as predictors ofgall bladder stones and cancer in post menopausal females in India.

• Journal of the Korean GEO-environmental Society
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• v.12 no.7
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• pp.67-76
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• 2011

In this present study, to evaluate a behavior characteristics of the sea dyke coastal covering stone by sea waves. sea waves act on coastal structures as an impact load. During impact loading, erosion and bluff slumping occur in the coastal structures. Also, the covering stone are worn down by wave impact. The sea dyke has been used near coastal region for protection of infra-structure since 1970s in Korea. The sea dyke consist of dredged sand and covering stone mainly. The damage type of covering stone has been reported since 1970s. However, the interaction of impact load by sea wave with the covering stone has not been investigated yet properly. Mainly damage type of covering stone is an abrasion. But the study of covering stone abrasion is not sufficient. Hence, In this study, it was analyzed the interaction of impact load by sea wave and the covering stone during sea wave action on coastal structures. In order to analyze the behavior characteristics of coastal covering stone considering the magnitude and period of impact loading and to evaluate the displacement increment of covering stone during impact load, numerical analysis was carried out considering impact loading by sea wave.

• Computers and Concrete
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• v.33 no.6
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• pp.707-724
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• 2024

This paper proposes a study of cement replacement with rice husk ash (RHA) and eggshell ash (ESA) for enhanced mechanical properties of geopolymer (GP) concrete with and without admixture. The main objective is to investigate the mechanical properties of GP with various replacement levels of Pozzolana Portland cement by RHA and ESA. The GP resistance to durability is examined and impact of ash materials on concrete's durability performance is determined. The environmental benefits of using agricultural waste materials in GP manufacturing minimize cement usage and CO2 emissions. The goal is to assess value of RHA-ESA of building material, paving stones for structures to lessen environmental impact. The novelty lies in use of ESA and RHA as partial replacements for cement and investigation of admixtures to enhance concrete properties, and reduce environmental impact. The research contributes by introducing a novel approach to reducing cement consumption by using ESA and RHA to address environmental concerns. It also explores the potential benefits of admixtures improving concrete performance and reducing environmental pollution. A study is carried with and without impacts of admixture to find compressive strength of GP cubes. The cement has been replaced by RHA and ESA in the range of (2.5%+7.5%, 5%+5%, 7.5%+2.5) by weight of cement for M20 mix. The compressive strength (CS) and split tensile strength (STS) at 7days, 14 days and 28 days is obtained as 21 N/mm2 at 7.5%RHA+2.5%ESA and 2.3 at 7.5%RHA+2.5%ESA, 24 N/mm2 at 7.5%RHA+2.5%ESA and 2.3 at 7.5%RHA+2.5%ESA, 28 N/mm2 at 7.5%RHA+2.5%ESA and 2.8 at 7.5%ESA respectively with normal curing condition.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.2049-2056
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• 2011

The reinforced-roadbed materials composed of crushed stones are used for preventing vertical deformation and reducing impact load caused by highspeed train. Repeated load application can induce deformation in the reinforced-roadbed layer so that it causes irregularity of track. Thus it is important to understand characteristics of permanent deformation in the reinforced-subbase materials. The characteristics of permanent deformation can be simulated by prediction model that can be obtained by performing repetitive triaxial test. The prediction model of permanent deformation is a key-role in construction of design method of track. The prediction model of permanent deformation is represented in usual as the hyperbolic function with increase of number of load repetition. The prediction model is sensitive to many factors including stress level etc. so that it is important to define parameters of the model as clearly as possible. Various data obtained from repetitive triaxial test and resonant column test using the reinforced-roadbed of crushed stone are utilized to develop a new prediction model based on concept of shear-stress ratio and elastic modulus. The new prediction model of permanent deformation can be adapted for developing design method of track in the future.

• Proceedings of the Korea Water Resources Association Conference
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• 2018.05a
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• pp.149-149
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• 2018

Prediction on initial motion of sediment is crucial to evaluate sediment transport and channel stability. The condition of incipient movement of sediment is characterized by bed shear stress, which is generated from force of moving water against the bed of the channel, and by critical shear stress, which depends on force resisting motion of sediment due to the submerged weight of the grains. When the bed shear stress exceeds the critical shear stress, sediment particles begin rolling and sliding at isolated and random locations. In Mountain River, debris flow frequently occurs due to heavy rainfall and can lead some natural stones from mountain slope into the bed river. This phenomenon could add additional forces to sediment transport system in the bed of river and also affect or change direction and magnitude of sediment movement. In this paper, evaluations on incipient motion of uniform coarse gravel under falling spheres impacts using small scale flume channel were conducted. The drag force of falling spheres due to water flow and length movement of falling spheres were investigated. The experiments were carried out in flume channel made by glass wall and steel floor with 12 m long, 0.6 m wide, and 0.6 m deep. The bed slopes were selected with the range from 0.7% to 1.5%. The thickness of granular layer was at least 3 times of diameter of granular particle to meet grain placement condition. The sphere diameters were chosen to be 4cm, 6 cm, 8 cm, 10 cm. The spheres were fallen in to the bed channel for critical condition and under critical condition of motion particle. Based on the experimental results, the Shields curve of particles Reynold number and dimensionless critical shear stress were plotted. The relationship between with drag force and the length movement of spheres were plotted. The pathways of the bed material Under the impact of spheres falling were analyzed.

• Journal of the Korean association of regional geographers
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• v.7 no.3
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• pp.14-28
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• 2001

This study is to discuss the problems due to the maldevelopment occurred at the reserved areas of natural environments of the Ulleung Island, Gyeongsangbuk-do province, and it also suggests the ways of solving them The types of the maldevelopment practiced on the Ulleung Island consist of the change of land use, the opening of a round road, the destruction of mountains for the construction of harbor, the development of tourist areas, and the construction of military facilities. The decreased habitat of animals and the pollution of drinking water are occurred by the change of land use. The destruction of ecological system is due to the opening of a round road. The damage of natural landscape and the change of ocean eco-system is closely related to the construction of harbor and the destruction of mountains. Finally, the damage of rare plants and the pollution of drinking water are due to the development of tourist areas and the construction of military facilities. In the followings, the ways of solving the problems occurred by the various types of maldevelopment are suggested. First, the planning of pro-environmental development has to be established and practiced to preserve rare plants which are damaged due to the change of land use. Second, the destruction of natural landscape and resources has to be minimized by the implementation of environmental impact assesment when road and harbor are constructed. Third, the stones needed for the development of islands ought to be imported from mainland. Fourth, the established tourist areas are needed to rationally manage and the potential tourist areas has to be transferred to the reserved areas of natural environments. Fifth, military facilities should be constructed though the cooperation of autonomous local government. Finally, government officers' and residents' conscience of protecting and reserving natural environments is needed, and government has to give residents financial supports.

• Journal of the Korean Institute of Landscape Architecture
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• v.27 no.3
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• pp.1-17
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• 1999

The purpose of this study is to evaluate the creation techniques of artificial wetland, one of biotopes developed to promote biodiversity in urban areas, and to look for improvement steps. Specifically, artificial wetland creation techniques were categorized into living environment and living creature classification. Being living conditions for creations, habitat environment was reviewed with a focus on water and soil environments. Living creatures were classified into plants, insects, fish, and birds. The evaluation of creation techniques was done in post-construction evaluation while considering the creation of habitats for living creatures. Intervention by users, changes in living environment and living species, and relevance of creation techniques were reviewed. Key results of this study are as follows. (1) Water environment for the living environment of creatures provides a suitable environment conditions for the living of creatures through a process easing the use of piped water. Various water depths and embankment appear to have a positive impact on the living of aquatic life. In particular, embankment covered in soil naturally played an important role as a place for the activities of aquatic insects and young fish as well as the growth of aquatic plants. (2) Various aquatic and ground plants to promote insect-diversity, shallow water, and old-tree logs had contributed greatly in increasing the types and number of insects. Aquatic insects. Aquatic insects were seen much particularly in areas where aquatic plants are rich but water is shallow than any other areas. (3) A space piled with stone to provide habitats for fish was not much used. However, it was observed that fish used embankment built with natural stones and embankment using logs in areas where water is deep. In addition, it was confirmed that 1,500 fish that had been released propagated using various depths and places for birth. (4) It was analyzed that techniques (creation of island, log setting, and creation of man-made bird nests) to provide habitats and to attract birds are not serving their roles. In such a case, it is believed that species had not increased due to the smallness as well as isolated features of the area. Based on theoretical review, they are judged to be areas that are likely to be used when a greater variety of birds is introduced. It is judged that attracting and keeping more birds at the site, such spaces need to be linked systematically in the future in terms of building eco-network while ensuring an adequate living areas. (5) In the study areas, users intervened greatly. As a result, a blockage was created preventing the normal growth of plants and non-indigenous plants were introduced. In order to limit the intervention by users, setting enough buffer zones, and environment education programs were urgently required. D/H=1>Hyangkyo> houses on the river>temples>lecture halls. D/H ratio of the backside areas is as follows. D/H=1>Hyangkyo>houses on the river>lecture halls. 4. Inner garden were planted deciduous than evergreen trees with Lagerstroemia indica. Enclosed dominant trees were planted by Pinus densiflora, Querces seuata. construct GEM strain, and examined for the expression and functional stability in microcosms.

• Korean Journal of Ecology and Environment
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• v.37 no.4 s.109
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• pp.462-468
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• 2004

Most of the surveys of periphyton carried out for environmental and ecosystem health assessment of streams have considered the impact made on their fixative substrates (stones, rocks, sand, silt, clay and other abiotic matters), but there has been virtually no research that considered moving substrates. This study attempted to make an analysis and assessment of the habitat environments of the microalgae attached to the skin surfaces of fish living in small streams, with a focus on their species composition and community structure. The dominant fish in the this survey were Zacco temmincki and Zacco platypus, which are usually found in the streams, and rivers, and they accounted for 62% and 19%, respectively, in relative abundance. Substrates of fish, a representative organism with the trait of moving a long distance, show a marked contrast with those of organisms fixed at a certain place. Characteristics of both the upstream and the downstream reach well reflected in the microalgae attached to the skin surface of fishes, of which diatoms took the major composition. The result of this observation is considered to be useful to provide basic data in assessment of stream health. Also it may be suggested as a biological tool for the assessment of aquatic environment in the future.

• Journal of the Korean Society of Radiology
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• v.17 no.5
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• pp.751-759
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• 2023

Breast ultrasonography is difficult to image in fatty breasts and to find micro-calcification, but the discovery of micro-calcification is very important for breast cancer screening. Among the color Doppler artifact of ultrasound, twinkle artifact mainly occur on strong reflectors such as stones or calcification in images, and evaluation methods using them are clinically being used. In this study, we are conducting experiments on the color Doppler settings of ultrasound equipment, such as repetition frequency, ensemble, persist, wall filtering, smoothing, linear density, and dissociation value, by producing a breast simulation phantom using the largest amount of calcium phosphate among breast implants. The purpose of this study was to improve the contrast of twinkle artifact in breast ultrasound examinations and to maximize their use in clinical practice. As a result, the pulse repetition frequency occurred in the range of 3.6 kHz to 7.2 kHz, and did not occur above 10.5 kHz. For ensembles, twinkle artifact occurred in all sizes of calcification under low conditions, and in threshold settings, the twinkle artifact increased slightly only under 80 to 100 conditions, and did not occur in 1 mm size calcification. Persist, wall filter, smoothing, and line density settings did not have much meaning in the setting variable because conditions did not increase by condition, and pulse repetition frequency, ensemble, and thresholds had the greatest impact on the twinkling artifact image. This study is expected to help examiners select optimal conditions to effectively increase twinkle artifact by adjusting color Doppler settings.

• Journal of the Korean Society of Clothing and Textiles
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• v.32 no.12
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• pp.1837-1847
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• 2008

The goal of this study is to express the image of chameleons-that change their colors by light, temperature and its mood-into the sexy styles of corresponding coquettish temperamental people in Wearable Art. The method used in this study was experimenting various production mediums, including creating the textured stretch fabric, in the process of expressing the conceptual characteristics of the chameleon in Wearable Art. The concept of the work was a concoction of 'tempting', 'splendid', 'brilliant', 'fascinating', etc. that highlighted the real disposition of the chameleon. The futuristic preference of the researcher was also implicated. "Comfortable" and "enjoyable" concepts via motions were improved with the its completeness. The point of the design and production is to express symbolically the chameleon in real life, analyzing its sleek body lines, conditional colors changing, outer skins and the cubic textures. The coquettish temperamental image, the conceptual image of the chameleon, was also expressed by implication into the whole work. The entire line of this work is body-conscious silhouette. It was symbolically selected to image the outline of the chameleon that has the slim and sleek body. The exposed back is intended to express symbolically the projected back bones of the chameleon. The hood of gentle triangle line expresses the smooth-lined head part. The irregular hemlines represent the elongated chameleon's tale. The chameleon with its colors of vivid tones is characterized the colors changing by its conditions. This point was importantly treated in the working process by trying the effects that the colors are seen slightly different according to the light and angles. The material was given the effect that its surface colors are seen different in lights and angles because of the wrinkles protruded lumpy-bumpy. The various stones of red and blue tones are very similar to the skin tones of the real chameleon, and their gradation makes the effect that the colors are visibly changed with each move. The textures of the chameleon were produced via the wrinkle effect of smoke-shape, which is the result of using the elastic threads on the basic mediums stitched with 50/50 chiffon and polyester along with velvet dot patterns. The stretching fabric by the impact of the elastic threads is as much suitable for making the body-conscious line. The stones are composed of acrylic cabochon and gemstone. They are symbolically expressed the lumpy and bumpy back skin of the chameleon and produced the effect of the colors visibly different. The primary technique used in this dress is the draping utilizing the biased grains. The front body piece is connected to the hood and joined to the back piece without any seam. For the irregular hemline flares, leaving the several rectangular pieces with bias grains, they were connected by interlocking. What defines the clothes is the person in action. Therefore, what decides the completeness of clothes might be its comfortable and enjoyable feeling by living and acting people. The chameleon dress could also reach its goal of comforting and pleasing Wearable Art in the process of studying the techniques and effects that visibly differentiate the colors. It is considered as a main point of the Wearable Art, which is a comfortable enjoyable clothing tempered with the artistic beauty.