• Title/Summary/Keyword: Immunity System

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A DELAY DYNAMIC MODEL FOR HIV INFECTED IMMUNE RESPONSE

  • BERA, S.P.;MAITI, A.;SAMANTA, G.P.
    • Journal of applied mathematics & informatics
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    • v.33 no.5_6
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    • pp.559-578
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    • 2015
  • Human Immune Deficiency Virus (or simply HIV) induces a persistent infection that leads to AIDS causing death in almost every infected individual. As HIV affects the immune system directly by attacking the CD4+ T cells, to exterminate the infection, the natural immune system produces virus-specific cytotoxic T lymphocytes(CTLs) that kills the infected CD4+ T cells. The reduced CD4+ T cell count produce reduced amount of cytokines to stimulate the production of CTLs to fight the invaders that weakens the body immunity succeeding to AIDS. In this paper, we introduce a mathematical model with discrete time-delay to represent this cell dynamics between CD4+ T cells and the CTLs under HIV infection. A modified functional form has been considered to describe the infection mechanism. Characteristics of the system are studied through mathematical analysis. Numerical simulations are carried out to illustrate the analytical findings.

Complexity Reduction Algorithm of Speech Coder(EVRC) for CDMA Digital Cellular System

  • Min, So-Yeon
    • Journal of Korea Multimedia Society
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    • v.10 no.12
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    • pp.1551-1558
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    • 2007
  • The standard of evaluating function of speech coder for mobile telecommunication can be shown in channel capacity, noise immunity, encryption, complexity and encoding delay largely. This study is an algorithm to reduce complexity applying to CDMA(Code Division Multiple Access) mobile telecommunication system, which has a benefit of keeping the existing advantage of telecommunication quality and low transmission rate. This paper has an objective to reduce the computing complexity by controlling the frequency band nonuniform during the changing process of LSP(Line Spectrum Pairs) parameters from LPC(Line Predictive Coding) coefficients used for EVRC(Enhanced Variable-Rate Coder, IS-127) speech coders. Its experimental result showed that when comparing the speech coder applied by the proposed algorithm with the existing EVRC speech coder, it's decreased by 45% at average. Also, the values of LSP parameters, Synthetic speech signal and Spectrogram test result were obtained same as the existing method.

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High-Resolution Interrogation Technique for Fiber Bragg crating Sensor Using Long-Period Fiber Grating Pair and Erbium-Doped fiber

  • Jung, Jae-Hoon;Lee, Yong-Wook;Lee, Byoung-Ho
    • Journal of the Optical Society of Korea
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    • v.6 no.1
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    • pp.5-12
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    • 2002
  • A novel interrogation scheme to detect fine Bragg wavelength shift using a long period fiber grating pair with erbium-doped fiber inserted between the two gratings is reported. The technique is shown to feature high resolution and much more immunity to temperature perturbation compared to the conventioned Mach-Zehnder interferometer demodulation system. For quasi-static strain measurement, this approach provides high wavelength resolution of 0.05 pm that corresponds to 41.7 ne in strain and $3.8 $\times$ 10^{-3}$$^{\circ}C$ in temperature. This interrogation system is also employed in dynamic measurement to obtain the minimum detectable strain perturbation of ~ 8.76 ne/H $z^{{\frac}{1}{2}}$ at 100 Hz. Moreover, this interrogation system has prominent thermal stability. This thermal stability comes from the fact that two arms of the interferometer, the core and cladding in erbium-doped fiber, are exposed to nearly the same environment .

Allograft Immune Reaction of Kidney Transplantation Part 1. Mechanism of Allograft Rejection (신이식 후 면역반응의 이해 - 1부. 이식 거부 반응의 기전 -)

  • Kang, Hee-Gyung
    • Childhood Kidney Diseases
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    • v.12 no.1
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    • pp.23-29
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    • 2008
  • Kidney allograft transplantation is the most effective method of renal replacement for end stage renal disease patients. Still, it is another kind of 'disease', requiring immunosuppression to keep the allograft from rejection(allograft immune reaction). Immune system of the allograft recipient recognizes the graft as a 'pathogen (foreign or danger)', and the allograft-recognizing commanderin-chief of adaptive immune system, T cell, recruits all the components of immune system for attacking the graft. Proper activation and proliferation of T cell require signals from recognizing proper epitope(processed antigen by antigen presenting cell) via T cell receptor, costimulatory stimuli, and cytokines(IL-2). Thus, most of the immunosuppressive agents suppress the process of T cell activation and proliferation.

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Real-Time Monitoring and Warning System for Slope Movements Using FBG Sensor. (광섬유격자 센서를 활용한 사면거동 실시간 안전 진단 시스템)

  • 장기태;정경선;김성환;박권제;이원효;김경태;강창국;홍성진
    • Proceedings of the Korean Geotechical Society Conference
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    • 2000.11b
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    • pp.60-76
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    • 2000
  • Early detection in real-time response of slope movements ensures tremendous saving of lives and repair costs from catastrophic disaster Therefore, it is essential to constantly monitor the performance and integrity of slope-stabilizing structures such as Rock bolt, Nail and Pile during or after installation. We developed a novel monitoring system using Fiber Bragg Grating (FBG)sensor. It's advantages are highly sensitivity, small dimension and electro-magnetic immunity. capability of multiplexing, system integrity, remote sensing - these serve real-time health monitoring of the structures. Real-time strain measurement by the signal processing program is shown graphically and it gives a warning sound when the monitored strain state exceeds a given threshold level so that any sign of abnormal disturbance on the spot can be easily perceived.

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Development of UFC/DC Data Communication method for XKO-1 using RS-422 Bus (RS422 버스를 이용한 저속통제기 UFC/DC 데이터 통신 기법 개발)

  • 양승열;김영택
    • Journal of the Korea Institute of Military Science and Technology
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    • v.5 no.2
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    • pp.123-131
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    • 2002
  • ASC(Avionics System Computer) was developed to control weapon delivery and navigation sensors, and to perform man-machine interface with pilots for XKO-1 aircraft. The data communications between ASC and UFC(Up Front Controller), DC(Data Concentrator) were implemented by RS422 serial data bus. Also, SCIL(Standard Computer Interface Library) was designed to facilitate control and management of the computer hardware resources and is embedded in the ASC. These structures have a merit of noise immunity and a reduction of wire harness for signal lines, and enable OFP(Operational Flight Program) programmers to use the SCIL easily without knowing hardware details. Manufactured system was on installed on XKO-1, and peformed for BIT(Built In Test) and interface test with UFC and DC. The test results show that it meets the system requirements.

Coexisting with the Coronavirus, How to Prepare for It (위드코로나 시대, 어떻게 준비할 것인가?)

  • Lee, Sun-Hee
    • Health Policy and Management
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    • v.31 no.3
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    • pp.241-243
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    • 2021
  • With the increase in vaccinations worldwide, the world is facing the era of coexisting with coronavirus disease 2019 (COVID-19). The government announced that it will change its focus of public health emergency response system, gradually toward daily recovery from November. Hence, this article reviews an overview of policy tasks to prepare for the era of coexistence with COVID-19. The three key policies that should be considered are as follow: (1) vaccination should be administered promptly to improve the immunity of the target population; (2) the government should advance the medical capability for critically ill patients and reorganize the patient delivery system; and (3) epidemiological surveillance system should be reformed in a direction to raise the social capacity.

A Study on the Degree of Need of Human Structure and Function Knowledge in Clinical Nurses (기초간호자연과학의 인체구조와 기능 내용별 필요도에 대한 연구)

  • Choe, Myoung-Ae;Byun, Young-Soon;Seo, Young-Sook;Hwang, Ae-Ran;Kim, Hee-Seung;Hong, Hae-Sook;Park, Mi-Jung;Choi, Smi;Lee, Kyung-Sook;Seo, Wha-Sook;Shin, Gi-Soo
    • Journal of Korean Biological Nursing Science
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    • v.1 no.1
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    • pp.1-24
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    • 1999
  • The purpose of this study was to define the content of requisite human structure and function knowledge needed for clinical knowledge of nursing practice. Subjects of human structure and function were divided into 10 units, and each unit was further divided into 21 subunits, resulting in a total of 90 items. Contents of knowledge of human structure and function were constructed from syllabus of basic nursing subjects in 4 college of nursing, and textbooks published by nurse scholars prepared with basic nursing sciences. The degree of need of 90 items was measured with a 4 point scale. The subjects of this study were college graduated 136 nurses from seven university hospitals in Seoul and three university hospitals located in Chonnam Province, Kyungbook Province, and Inchon. They have been working at internal medicine ward, surgical ward, intensive care unit, obstetrics and gynecology ward, pediatrics ward, opthalmology ward, ear, nose, and throat ward, emergency room, rehabilitation ward, cancer ward, hospice ward, and their working period was mostly under 5 years. The results were as follows: 1. The highest scored items of human structure and function knowledge necessary for nursing practice were electrolyte balance, blood clotting mechanism and anticoagulation mechanism, hematopoietic function, body fluid balance, function of plasma, and anatomical terminology in the order of importance. The lowest scored items of human structure and function knowledge necessary for nursing practice was sexual factors of genetic mutation. 2. The highest order of need according to unit was membrane transport in the living unit, anatomical terminology in movement and exercise unit, mechanism of hormone function in regulation and integration unit, component and function of blood in oxygenation function unit, structure and function of digestive system in digestive and energy metabolism unit, temperature regulation in temperature regulation unit electrolyte balance in body fluid and electrolyte unit, concept of immunity in body resistance unit, and genetics terminology in genetics unit. The highest order of importance according to subunit was membrane transportation in cell subunit, classification of tissues in tissue unit, function of skin and skin in skin subunit, anatomical derivatives of the skeleton subunit, classification of joints in joint subunit, an effect of exercise on muscles in muscle subunit, function of brain in nervous system subunit, special sense in sensory subunit mechanism of hormone function in endocrine subunit, structure and function of female reproductive system in reproductive system unit, structure and function of blood in blood unit, structure of heart, electrical and mechanical function in cardiovascular system unit, structure of respiratory system in respiratory system subunit, structure and function of digestive system in digestive system subunit, hormonal regulation of metabolism in nutrition and metabolism subunit, function of kidney in urologic system subunit, electolyte balance in body fluid, electolyte and acid-base balance subunit. 3. The common content of human structure and function knowledge need for all clinical areas in nursing was structure and function of blood, hematopoietic function, function of plasm, coagulation mechanism and anticoagulation mechanism, body fluid, electrolyte balance, and acid-base balance. However, the degree of need of each human structure and function knowledge was different depending on clinical areas. 4. Significant differences in human structure and function knowledge necessary for nursing practice such as skin and derivatives of the skin, growth and development of bone, classification of joint, classification of muscle, structure of muscle, function of muscle, function of spinal cord, peripheral nerve, structure and function of pancrease, component and function of blood, function of plasma, structure and function of blood, hemodynamics, respiratory dynamics, gas transport, regulation of respiration, chemical digestion of foods, absorption of foods, characteristics of nutrients, metabolism and hormonal regulation, body energy balance were demonstrated according to the duration of work. 5. Significant differences in human structure and function knowledge necessary for nursing practice such as classification of tissue, classification of muscles, function of muscles, muscle metabolism, classification of skeletal muscles, classification of nervous system, neurotransmitters, mechanism of hormone function, pituitary and pituitary hormone, structure and function of male reproductive organ, structure and function of female reproductive organ, component and function of blood, function of plasma, coagulation mechanism and anticoagulation mechanism, gas exchange, gas transport, regulation of respiration, characteristics of nutrients, energy balance, function of kidney, concept of immunity, classification and function of immunity were shown according to the work area. Based on these findings, all the 90 items constructed by Korean Academic Society of Basic Nursing Science should be included as contents of human structure and function knowledge.

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Investigation of a Hybrid HVDC System with DC Fault Ride-Through and Commutation Failure Mitigation Capability

  • Guo, Chunyi;Zhao, Chengyong;Peng, Maolan;Liu, Wei
    • Journal of Power Electronics
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    • v.15 no.5
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    • pp.1367-1379
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    • 2015
  • A hybrid HVDC system that is composed of line commutated converter (LCC) at the rectifier side and voltage source converter (VSC) in series with LCC at the inverter side is studied in this paper. The start-up strategy, DC fault ride-through capability, and fault recovery strategy for the hybrid HVDC system are proposed. The steady state and dynamic performances under start-up, AC fault, and DC fault scenarios are analyzed based on a bipolar hybrid HVDC system. Furthermore, the immunity of the LCC inverter in hybrid HVDC to commutation failure is investigated. The simulation results in PSCAD/EMTDC show that the hybrid HVDC system exhibits favorable steady state and dynamic performances, in particular, low susceptibility to commutation failure, excellent DC fault ride-through, and fast fault recovery capability. Results also indicate that the hybrid HVDC system can be a good alternative for large-capacity power transmission over a long distance byoverhead line.

Power Line Communication-based Heated Glass Temperature Control System (전력선통신을 이용한 선박 및 건축용 발열유리 온도제어 시스템)

  • Lee, Su-Hyeong;Kim, In-Dong
    • The Transactions of the Korean Institute of Power Electronics
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    • v.20 no.2
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    • pp.105-114
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    • 2015
  • Heated glasses are widely used to prevent surface condensation and freezing in ship and building windows. This study proposes a heated glass temperature control system composed of power and control circuits to control the temperature of heated glasses. The proposed temperature control system adopts a digital controller instead of a conventional analog controller. Thus, the proposed system has better characteristics, such as precise setup and control of glass temperature, setup and control of output power, and control mode change between ON/OFF and phase controls. The system can also implement multi-functional control algorithms. The control characteristics are not dependent upon external disturbances, such as ambient temperature and electrical noises. Furthermore, the proposed temperature control system utilizes the power line communication (PLC) method to control the number of heated glasses without any extra communication lines. The system proposes a new communication protocol with strong immunity to electrical switching noises. A new sensorless algorithm is used to detect the temperature of the heated glass. This study presents the design guidelines in detail and its effectiveness are confirmed by implementing a 4-kw prototype temperature control system.