• 생물정신의학
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• 제15권3호
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• pp.147-151
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• 2008

This review briefly summarizes the relevant knowledge of psychoneuroimmunological basis for neuroimmunology, with particular emphasis on bidirectional neural-immune interactions. The immune system and the nervous system maintain extensive communication, including hardwiring of sympathetic and parasympathetic nerves to lymphoid organs. Immune system is modulated by various neurotransmitters such as acetylcholine, norepinephrine, substance P and histamine. Neuroendocrine hormones such as corticotrophin-releasing hormone(CRH) or substance P regulate cytokine balance. The immune system modulates brain activity including sleep and body temperature. Recent studies have revealed that psychological factors which influence immunity and immune-related disease may modulate brain-to -immune interaction. But, we still await the scientific research and evidences to prove whether or how behavioral or treatment intervention of stress can influence the development, progress or prevention of a specific disease.

• 한국정보통신학회논문지
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• 제5권1호
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• pp.52-60
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• 2001

본 논문에서는 나카가미 페이딩 환경에서 다중 반송파 MFSK-DPSK/DS-CDMA 합성 변조기법을 제안하였다. 또한, 다중경로 페이딩에 강한 특성과 주파수 이용 효율이 높은 다중반송파 DS-CDMA 합성변소 방식을 같이 사용하여 분석하였다. 그러한 변조방식은 비동기식 MFSK와 MFSK에 기반한 DPSK를 이용한 결합 주파수 위상 합성변조 방식이다. 결과로부터 전력효율과 대역폭 효율이 일반적인 통신 시스템보다 다중캐리어 합성 변조시스템이 효율을 개선시킬 수 있음을 알았다.

• 전자공학회논문지A
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• 제28A권11호
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• pp.855-865
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• 1991

A simple method for analysis of serial search burst-format direct-sequence spread-spectrum (DS-SS) code acquisition system had been recently proposed, and therein, the effect of the code autocorrelation sidelobes on the performance of DS-SS code acquisition system has been assessed [4],[5]. In this paper, a new hybrid scheme which combines the serial search with maximum likelihood search is proposed to eliminate the deleterious effect of code autocorrelation sidelobes, and the performance is analyzed for the additive withe Gaussian noise (AWGN) channels. To analyze the performance of this system, we have generalized the method used in [4],[5] to arbitrary burst-format DS-SS acquisition schemes. The results show that a new hybrid scheme has good immunity against the effect of code autocorrelation sidelobes. Thevalidity of the presented approach has been confirmed form the results of simulation.

• Journal of Advanced Marine Engineering and Technology
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• 제28권8호
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• pp.1286-1290
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• 2004

This paper describes the anti-corrosion system on underwater structures of ships. Metals and alloys have several positions in the series such as immunity, corrosion and passivity. The iron potential has to change from the corrosion position to the anodic protection or cathodic protection for preventing corrosion by providing corrosion protection system such as ICCP(Impressed Current Cathodic Protection). The purpose of ICCP system is to eliminate the rusting or corrosion, which occurs on metal immersed in water. The system includes a power supply unit, which consists of a transformer, a converter. a controller, etc. This paper presents the protection performance of ICCP under dynamic condition such as velocity. The variation of potential and current density with time and environment factors are also described Finally, the experimental results will be explained and analysed.

• 전자공학회논문지A
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• 제31A권6호
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• pp.61-69
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• 1994

For distortion-invariant recognition of Korean characters, a holographic implementation of an optical associative memory system is proposed. The structure of the proposed system is a single-layer neural network employing interconneclion matrix, thresholding and feedback. To provide the interconnection matrix, we use two CGII's which are placed on intermcdiate plane of cascaded Vander Lugt corrclators to form an optical memory loop. The holographic correlator stores reference images in a hologram and retrives them in a coherently illuminated feedback loop. An input image which maybe noisy or incomplete, is applicd to the system and simultaneously correlated optically with all of the stord images. These correlations are throsholed and fed back to the input, where the strongest correlation reinforces the input image. The enhanced image passes arround the loop repeatedly, approaching the stored image more closely on each pass until the system stabilizes on the desired image. The computer simulation results show that the proposed Korean Character recognition algorithm has high discrimination capability and noise immunity.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2006년도 하계종합학술대회
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• pp.871-872
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• 2006

In this paper, we designed bio-signal acquisition system in Magnetic Resonance Imager(MRI) Environment. In MRI Environment, Strong RF Pulse and Gradient Field Switching Noise exist and can cause distortion of ECG. By this, ECG can lose their important information. So we proposed a bio-signal acquisition system with robust immunity to RF pulse and gradient switching noise. In conclusions, the proposed system showed the prevent saturation of measured biosignal and possibility of using cardiac gating and respiration gating method.

• 한국자기공명학회논문지
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• 제25권3호
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• pp.39-44
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• 2021

The CRISPR-Cas system provides adaptive immunity for bacteria and archaea against invading phages and foreign plasmids. In the Class 1 CRISPR-Cas system, multi-subunit Cas proteins assemble with crRNA to bind to DNA targets. To disarm the bacterial defense system, bacteriophages evolved anti-CRISPR (Acr) proteins that actively inhibit the host CRISPR-Cas function. Here we report the backbone resonance assignments of AcrIF7 protein that inhibits the type I-F CRISPR-Cas system of Pseudomonas aeruginosa using triple-resonance nuclear magnetic resonance spectroscopy. We employed various computational methods to predict the structure and binding interface of AcrIF7, and assessed the model with experimental data. AcrIF7 binds to Cas8f protein via flexible loop regions to inhibit target DNA binding, suggesting that conformational heterogeneity is important for the Cas-Acr interaction.

• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3903-3907
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• 2013

Background: Patients with colorectal cancer are usually treated with chemotherapy, which reduces the number of blood cells, especially white blood cells, and consequently increases the risk of infections. Some research studies have reported that aromatherapy massage affects the immune system and improves immune function by, for example, increasing the numbers of natural killer cells and peripheral blood lymphocytes. However, there has been no report of any study which provided good evidence as to whether aromatherapy with Thai massage could improve the immune system in patients with colorectal cancer. The objectives of this study were to determine whether the use of aromatherapy with light Thai massage in patients with colorectal cancer, who have received chemotherapy, can result in improvement of the cellular immunity and reduce the severity of the common symptoms of side effects. Materials and Methods: Sixty-six patients with colorectal cancer in Phichit Hospital, Thailand, were enrolled in a single-blind, randomised-controlled trial. The intervention consisted of three massage sessions with ginger and coconut oil over a 1-week period. The control group received standard supportive care only. Assessments were conducted at pre-assessment and at the end of one week of massage or standard care. Changes from pre-assessment to the end of treatment were measured in terms of white blood cells, neutrophils, lymphocytes, CD4 and CD8 cells and the CD4/CD8 ratio and also the severity of self-rated symptom scores. Results: The main finding was that after adjusting for pre-assessment values the mean lymphocyte count at the post-assessment was significantly higher (P=0.04) in the treatment group than in the controls. The size of this difference suggested that aromatherapy with Thai massage could boost lymphocyte numbers by 11%. The secondary outcomes were that at the post assessment the symptom severity scores for fatigue, presenting symptom, pain and stress were significantly lower in the massage group than in the standard care controls. Conclusions: Aromatherapy with light Thai massage can be beneficial for the immune systems of cancer patients who are undergoing chemotherapy by increasing the number of lymphocytes and can help to reduce the severity of common symptoms.

• 대한수의학회지
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• 제29권3호
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• pp.283-289
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• 1989

In order to measure in vitro cell mediated immunity in the guinea pigs sensitized with the killed bacilli of Mycobacterium bovis ($AN_5$), M avium (serotype 2), M tuberculosis and M intracellulare (serotype 8), leukocyte adherence inhibition (LAI) test was established using the antigens of purified protein derivatives (PPD) tuberculin. By using LAI test, specificity of cell-mediated immune responses of the guinea pigs inoculated with various Mycobacterium spp was investigated, and comparison between values of LAI and skin test was also made to evaluate the specificity of the newly designed test. The results obtained throughout the experiments were summarized as follows; 1. The optimal concentration of PPD antigens for LAI test was 1 to 2mg per ml of medium. 2. When the leukocytes of guinea pigs sensitized with both M bovis($AN_5$) and M avium (serotype 2) for 2 to 8 weeks were incubated with homologous or heterologous PPD antigens, mean values of LAI test were $61.2{\pm}11.2$ and $65.6{\pm}5.1%$ in homologous PPD antigens respectively, while $30.0{\pm}3.7$ and $32.8{\pm}5.7%$ in heteNlogous PPD antigens, showing the prominently high value of LAI in the homologous syst,em (p<0.01). 3. When the leukocytes of guinea pigs sensitized with both M tuberculosis and M intracellulare (serotype 8) for 2 to 8 weeks were incubated with homologous and heterologous PPD antigens, mean values of LAI test were $67.9{\pm}2.9$ and $66.9{\pm}5.0%$ in homologous PPD antigens, while $27.4{\pm}7.4$ and $24.4{\pm}7.1%$ in heterologous PPD antigens, showing the prominently high value of LAI in the homologous system (p<0.01). 4. Comparing with the specificity of LAI and skin tests on the basis of the value obtained from the homologous system, deviation of reaction was revealed to be 49.5 to 100.2 in LAI test, and -15.9 to 52.0 in skin test.

• 비교문화연구
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• 제45권
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• pp.245-268
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• 2016

2008년 개봉된 영화 <도쿄!>는 미셸 공드리 감독의 <인테리어 디자인>, 레오 카락스 감독의 <메르드>, 봉준호 감독의 <흔들리는 도쿄>로 구성되어 있다. 이 세 편의 단편은 모두 도시적 삶에서 비롯된 자기 소외의 경험을 다룬다. 도시에서 어떻게 자기 자신으로 살아남을 것인가? 삶의 문제는 근본적으로 삶의 자기 유지와 관련되어 있다. <도쿄!>에서 세 명의 감독이 펼쳐놓은 이야기는 이러한 도시적 삶이 자기-보존적이면서 동시에 자기-해체적인 양상을 띠고 있음을 보여준다. 도시는 문을 열면서 닫고 닫으면서 여는 이중구속의 역설적 움직임이 지속적으로 이루어지는 공간이다. 도시적 삶은 이러한 움직임 속에서 데리다가 무한하게 확장할 것을 제안했던 자가면역적 논리에 항상 노출되어 있다. 삶의 문제는 근본적으로 삶의 자기 유지와 관련된다. <도쿄!>를 구성하는 세 편의 단편에서 도시적 삶은 전유적, 탈전유적, 비전유적인 존재 양상을 통해 자기성을 드러낸다. 전유적 자기가 타자를 다시 제 소유로 삼음으로써 자기를 더욱 강화한다면 비전유적 자기는 순수하게 동일한 것으로 남고자 스스로를 방어한다. 이러한 도시적 삶의 양상은 필연적으로 자가면역적 반작용에 부딪칠 수밖에 없다. 오직 탈전유적 자기만이 자가면역적 반작용 속에서 약속 안의 위협을 감수하며 자기성의 움직임의 또 다른 양상의 가능성을 예표한다.