• The Korean Journal of Nuclear Medicine Technology
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• v.15 no.2
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• pp.72-75
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• 2011

Purpose: The HSV1-tk reporter gene system is the most widely used system because of its advantage is that it is possible to monitor directly without the introduction of a separate reporter gene in case of HSV1-tk suicide gene therapy. This study was performed to automate 9-(4-[$^{18}F$] Fluoro-3-hydroxymethylbutyl) guanine ([$^{18}F$] FHBG) that are widely used as substrate for the HSV1-tk reporter gene in living organisms with positron emission tomography (PET) and find the optimized conditions of synthesis. Materials and Methods: Fully automated synthesis of [$^{18}F$] FHBG was performed using Explora-RN (CTI, USA) module. We have changed of reaction time (3, 5, 10 min) and temperature (110, 120, $130^{\circ}C$) for the optimized conditions of synthesis. Also we experimented to find the optimal concentration of precursor (5, 7, 10 mg). Results: [$^{18}F$] FHBG was purified by HPLC system and collected at around 10-12 min. Synthesis using Explora-RN module showed a $32.0{\pm}1.2%$ yield of radiochemical (decay corrected), the purity was greater than 98%. And the entire synthesis time was less than 48 min. Temperature of the highest synthesis yield was $130^{\circ}C$, reaction time was 5 minutes and concentration of precursor was 10 mg (recommended volume in manual) (n=36). In contrast to radiochemical yield of precursor 10 mg ($32{\pm}1.2%$), yield of 5 and 7 mg precursor was unstable. Conclusion: Automation of [$^{18}F$] FHBG synthesis at Explora-RN module has been completed. In addition, we were able to obtain optimized reaction time, temperature and concentration of precursor. Therefore this study would be provided more rapid synthesis and higher radiochemical yield.

• Journal of Radiation Protection and Research
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• v.39 no.3
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• pp.150-158
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• 2014

Radiation-related practitioners and radiation-treated patients at medical institutions are inevitably exposed to radiation for diagnosis and treatment. Although standards for maximum doses are recommended by the International Commission on Radiological Protection (ICPR) and the International Atomic Energy Agency (IAEA), more direct and available measurement and analytical methods are necessary for optimal exposure management for potential exposure subjects such as practitioners and patients. Thus, in this study we developed a system for real-time radiation monitoring at a distance that works with existing portable device. The monitoring system comprises three parts for detection, imaging, and transmission. For miniaturization of the detection part, a scintillation detector was designed based on a silicon photomultiplier (SiPM). The imaging part uses a wireless charge-coupled device (CCD) camera module along with the detection part to transmit a radiation image and measured data through the transmission part using a Bluetooth-enabled portable device. To evaluate the performance of the developed system, diagnostic X-ray generators and sources of $^{137}Cs$, $^{22}Na$, $^{60}Co$, $^{204}Tl$, and $^{90}Sr$ were used. We checked the results for reactivity to gamma, beta, and X-ray radiation and determined that the error range in the response linearity is less than 3% with regard to radiation strength and in the detection accuracy evaluation with regard to measured distance using MCNPX Code. We hope that the results of this study will contribute to cost savings for radiation detection system configuration and to individual exposure management.

• Geophysics and Geophysical Exploration
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• v.13 no.4
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• pp.315-322
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• 2010

The phase-screen and the split-step Fourier migrations, which are implemented in both the frequency-wavenumber and frequency-space domains by using one-way scalar wave equation, allow imaging in laterally heterogeneous media with less computing time and efficiency. The generalized-screen migration employs the series expansion of the exponential, unlike the phase-screen and the split-step Fourier migrations which assume the vertical propagation in frequency-wavenumber domain. In addition, since the generalized-screen migration generalizes the series expansion of the vertical slowness, it can utilize higher-order terms of that series expansion. As a result, the generalized-screen migration has higher accuracy in computing the propagation with wide angles than the phase-screen and split-step Fourier migrations for media with large and rapid lateral velocity variations. In this study, we developed a 2D prestack generalized-screen migration module for imaging a complex subsurface efficiently, which includes various dips and large lateral variations. We compared the generalized-screen propagator with the phase-screen propagator for a constant perturbation model and the SEG/EAGE salt dome model. The generalized-screen propagator was more accurate than the phase-screen propagator in computing the propagation with wide angles. Furthermore, the more the higher-order terms were added for the generalized-screen propagator, the more the accuracy was increased. Finally, we compared the results of the generalizedscreen migration with those of the phase-screen migration for a model which included various dips and large lateral velocity variations and the synthetic data of the SEG/EAGE salt dome model. In the generalized-screen migration section, reflectors were positioned more accurately than in the phase-screen migration section.

• Korean Journal of Agricultural and Forest Meteorology
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• v.21 no.2
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• pp.97-109
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• 2019

Degree days have been determined using temperature data measured at nearby weather stations to a site of interest to produce information for supporting decision-making on agricultural production. Alternatively, the data products of Moderate Resolution Imaging Spectroradiometer (MODIS) can be used for estimation of degree days in a given region, e.g., Korean Peninsula. The objective of this study was to develop a simple tool for processing the MODIS product for estimating cooling degree days (CDD), which would help assessment of heat stress conditions for a crop as well as energy requirement for greenhouses. A set of scripts written in R was implemented to obtain temperature profile data for the region of interest. These scripts had functionalities for processing spatial data, which include reprojection, mosaicking, and cropping. A module to extract air temperature at the surface pressure level was also developed using R extension packages such as rgdal and RcppArmadillo. Random forest (RF) models, which estimate mean temperature and CDD with a different set of MODIS data, were trained at 34 sites in South Korea during 2009 - 2018. Then, the values of CDD were calculated over Korean peninsula during the same period using those RF models. It was found that the CDD estimates using the MODIS data explained >74% of the variation in the CDD measurements at the weather stations in North Korea as well as South Korea. These results indicate that temperature data derived from the MODIS atmospheric products would be useful for reliable estimation of CDD. Our results also suggest that the MODIS data can be used for preparation of weather input data for other temperature-based agro-ecological models such as growing degree days or chill units.

• Korean Journal of Optics and Photonics
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• v.23 no.6
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• pp.255-263
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• 2012

In this paper, we designed a tabletop display which enables two viewers each to see a different image simultaneously within his/her defined viewing zone. In order to construct the designed viewing zones, we found the basic design conditions for a parallax barrier with a commercial LCD panel. As the viewing zones for two viewers are formed with only two view-point design, the interval between the center positions of each viewing zone and the width of each viewing zone are small compared to designed values. We analyzed the primary cases, introduced two modified design methods to enlarge the interval and the width of the viewing zones, and simulated their characteristics. As designed with six unit view-point and each viewing zone of each viewer is formed with a merged view-point, we found that adequate interval and width of viewing zones can be made, and we verified it in comparison with the tabletop display module that we fabricated.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.1
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• pp.73-76
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• 2010

The issue of inspection and characterization of microstructures has emerged as a major consideration in design, fabrication, and detection of MEMS devices. However, the conventional measurement techniques, including scanning electron microscopy (SEM) imaging, atomic force microscopy (AFM) scanning, and mechanical surface profiler, require often destructive process or may be difficult to measure with a wafer scale. In this paper, we characterize the surface profiles of microstructures using an optical scanner based on a DVD pick-up module. Scanning images of the microstructures are successfully generated using the intensity of reflected light from different depths of the surface profiles, based on the focus error signal (FES) from photodiodes. It is shown that the proposed optical scanner can be used as an alternative measurement system with high performance and low cost, compared to conventional measurement techniques.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.593-596
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• 2005

The MSC is a remote sensing instrument with very high performance that is to be installed on KOMPSAT2 satellite. The MSC consists of EOS (Electro-Optic Subsystem), PMU (Payload Management Unit) and PDTS (Payload Data Transmission Subsystem). PMU controls and monitors all the other payload units by sending commands and collecting telemetry. PMU is in charge of interfacing between payload system and satellite bus system. PMU gets commands from ground-station via OBC (On-Board Computer) that is a main controller of the satellite bus system and sends telemetry to the ground-station via OBC. There is a processor module, called SBC (Single Board Computer) in the PMU. The SBC is a main controller of the MSC system. The main roles of the SBC are payload mission management, command validation and execution, telemetry collection and monitoring, ancillary data handling, event reporting, power control of payload sub-units and communication with these units. Intel's 80486DX2 processor has been used for the SBC. Due to the fact that the SBC plays important roles for imaging mission execution and handles a lot of control data that is required for payload operation, it is required to make analysis of the CPU load when it is in maximum operation mode. In this paper, the analysis and measurement results of the SBC throughput in the maximum operation mode.

• Computers and Concrete
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• v.10 no.2
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• pp.135-147
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• 2012

At mesoscale, concrete is considered as a three-phase composite material consisting of the aggregate particles, the cement matrix and the interfacial transition zone (ITZ). The reconstruction of the internal structures for concrete composites requires the identification of the boundary of the aggregate particles and the cement matrix using digital imaging technology followed by post-processing through MATLAB. A parameter study covers the subsection transformation, median filter, and open and close operation of the digital image sample to obtain the optimal parameter for performing the image processing technology. The subsection transformation is performed using a grey histogram of the digital image samples with a threshold value of [120, 210] followed by median filtering with a $16{\times}16$ square module based on the dimensions of the aggregate particles and their internal impurity. We then select a "disk" tectonic structure with a specific radius, which performs open and close operations on the images. The edges of the aggregate particles (similar to the original digital images) are obtained using the canny edge detection method. The finite element model at mesoscale can be established using the proposed image processing technology. The location of the crack determined through the numerical method is identical to the experimental result, and the load-displacement curve determined through the numerical method is in close agreement with the experimental results. Comparisons of the numerical and experimental results show that the proposed image processing technology is highly effective in reconstructing the internal structures of concrete composites.

• Cartoon and Animation Studies
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• s.48
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• pp.199-215
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• 2017

Recently, a drone is used for the general purpose application although the drone was builtfor the military purpose. A drone is actively used for the creation of contents, and an image acquisition. In this paper, we develop a 3D library module platform using 3D mesh model data, which is generated by a drone image and its point cloud. First, a lot of 2D image data are taken by a drone, and a point cloud data is generated from 2D drone images. A 3D mesh data is acquired from point cloud data. Then, we develop a service library platform using a transformed 3D data for multi-purpose uses. Our platform with 3D data can minimize the cost and time of contents creation for special effects during the production of a movie, drama, or documentary. Our platform can contribute the creation of experts for the digital contents production in the field of a realistic media, a special image, and exhibitions.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.30 no.6
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• pp.124-129
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• 2002

KAISTAT-4 is the fourth experimental microsatellite of KITSAT series which has been developed by Satellite Technology Research Center of KAIST for the last two years. The launch of KAISTSAT-4 is scheduled in 2003. The primary experimental payloads consist of Far-ultraviolet Imaging Spectrograph and Space Physis Package. In a similar way to KITSAT series, the interior of KAISTSAT-4 comprises mainly a set of stacked aluminium-alloy module boxes, each being capable of acting as the primary load path in the mechanical structure. The KAISTSAT-4 qualification model is now designed, fabricated, integrated, and tested to verify if the electrical and mechanical components work and can withstand the launch environments. All the required structural tests have been performed to a sufficient degree to satisfy the intent of the test requirements. This paper presents the structural system and launch environmental test results of KAISTSAT-4 qualification model.