• 제목/요약/키워드: Illegal Distribution

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Quantitative Analysis and Enantiomeric Separation of Ephedra Alkaloids in Ma Huang Related Products by HPLC-DAD and UPLC-MS/MS

  • Kyoung-Moon Han;Jinwoo Hwang;Sun Hee Lee;Boreum Park;Hyungil Kim;Sun Young Baek
    • Natural Product Sciences
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    • v.28 no.4
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    • pp.168-180
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    • 2022
  • Ephedra is a genus of the Ephedraceae family and is found in temperate regions, such as Central Asia and Europe. Among the various ephedra species, Ma Huang (Ephedra herb) is derived from the aerial parts of Ephedra sinica S tapf, Ephedra equisetina Bunge, and Ephedra intermedia Schrenk & C.A. Mey. Ma Huang contains various ephedra alkaloids, including (-)-ephedrine, (+)-pseudoephedrine, (-)-norephedrine, (+)-norpseudoephedrine, (-)-methylephedrine, and (+)-methylpseudoephedrine, which are found naturally as single enantiomers, although they can be prepared as racemates. Although the use of Ma Huang in foods is prohibited in Korea, products containing Ma Huang can be imported, and so it is necessary to develop a suitable analytical technique for the detection of Ma Huang in foods. Herein, we report the development of analytical methods for the detection of ephedra alkaloids in products containing Ma Huang. Following sample purification by solid phase extraction, quantitative analysis was performed using ultra-performance liquid chromatography-triple quadrupole mass spectrometry (UPLC-MS/MS). Additionally, the enantiomers were successfully separated using HPLC-DAD. We successfully analyzed various food samples, where the ephedra alkaloids were qualitatively and quantitatively determined, and the enantiomers were separated. It is expected that these methods may contribute toward preventing the distribution of illegal products containing Ma Huang.

Development of a Model for Identifying Drug Organizations and Their Scale through Tweet Clustering

  • Jin-Gyeong Kim;Eun-Young Park;Da–Sol Kim;Cho-Won Kim;Jiyeon Kim
    • Journal of the Korea Society of Computer and Information
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    • v.29 no.10
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    • pp.207-218
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    • 2024
  • In this paper, we propose a model for identifying drug trafficking organizations and assessing their scale by collecting drug promotional tweets from the social media platform 'X,' with a focus on investigating drug crimes that frequently occur among teenagers and young adults. Recently, various cyber crimes, such as drug distribution, illegal gambling, and sex offense, have been on the rise, exploiting the anonymity provided by social media. Drug trafficking organizations, in particular, operate in a decentralized cell structure, where each member receives anonymous instructions regarding only their specific role and is not directly connected to other members. To track these types of crimes, we designed experimental scenarios using various clustering algorithms, such as K-means Clustering and Spectral Clustering, alongside text embedding models like BERT (Bidirectional Encoder Representations from Transformers) and GloVe (Global Vectors for Word Representation). Furthermore, the clustering results derived from each scenario are validated using Jaccard Similarity and a full-scale investigation. We then analyze tweet clusters identified as the same drug organization across all scenarios, prioritizing the identification of high-priority accounts for cyber investigations.

A Research on Management System of Herbal Medicine in Common Use for Food and Medicine (식약공용 한약재의 관리 방안에 관한 연구)

  • Kweon, Kee-Tae
    • The Korea Journal of Herbology
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    • v.27 no.2
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    • pp.25-29
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    • 2012
  • Objectives : This article reviews a solution preventing the illegal distribution of herbal medicine in common use for food and medicine and risks on public health by conducting safety management of food and medicine. Also, this article would like to contribute to improvement of public health treating diseases in compliance with accurate diagnosis and prescription of Oriental Medicine Doctor("OMD")'s. Methods : An approach in this research can be categorized into two : first, to examine the current administrative situation and problems of herbal medicine in common use for food and medicine based on policy documents of Ministry of Health and Welfare and Korea Food and Drug Adminstration("KFDA") and academic articles of the herbal medicine;second, to find reasonable administrative solutions to solve the problems. Solutions : A solution is to strengthen the management level of herbal medicine in common use for food and medicine by selecting 117 items as target items requiring concentrated management. In case herbal medicine is imported for food, KFDA strengthens the quality management level of herbal medicine by making use of inspection frequency at random, collecting and verifying herbal medicine on the market. However, KFDA decides to maintain current different quality specification system of food and medicine reflecting a civil complaint that quality specification of food and medicine should separately managed according to the purpose of use. Herbal medicine as medicine that is functioned as treating diseases and alleviating symptoms, unlike herbal medicine for food, can cure all kinds of diseases by recovering inner balance of human body, making use of other properties of herbal medicine. Medicine has its own properties. If a doctor uses properties of medicine appropriately, he cures diseases. If a doctor uses herbal medicine inappropriately. he may damage human body. Thus, whether side effects of medicine depend on a doctor who uses herbal medicine. Conclusions : All herbal medicine will be supplied into the market after strict safety control of manufacturers of herbal medicine according to the revised Pharmaceutical Affairs Act, beginning in April, 2012. Thus, people can take safer and more reliable herbal medicine through strengthening safety management of herbal medicine and improving quality and transparency in the distribution system. Herbal medicine should appropriately be prescribed by licensed OMD because herbal medicine is used to treat diseases and alleviate symptoms, unlike herbal medicine for food.

Study of DRM Application for the Portable Digital Audio Device (휴대용 디지털 오디오 기기에서의 DRM 적용에 관한 연구)

  • Cho, Nam-Kyu;Lee, Dong-Hwi;Lee, Dong-Chun;J. Kim, Kui-Nam;Park, Sang-Min
    • Convergence Security Journal
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    • v.6 no.4
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    • pp.21-27
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    • 2006
  • With the introduction of sound source sharing over the high speed internet and portable digital audio, the digitalization of sound source has been rapidly expanded and the sales and distribution of sound sources of the former offline markets are stagnant. Also, the problem of infringement of copyright is being issued seriously through illegal reproduction and distribution of digitalized sound sources. To solve these problems, the DRM technology for protecting contents and copyrights in portable digital audio device began to be introduced. However, since the existing DRM was designed based on the fast processing CPU and network environment, there were many problems in directly applying to the devices with small screen resolution, low processing speed and network function such as digital portable audio devices which the contents are downloadable through the PC. In this study, the DRM structural model which maintains similar security level as PC environment in the limited hardware conditions such as portable digital audio devices is proposed and analyzed. The proposed model chose portable digital audio exclusive device as a target platform which showed much better result in the aspect of security and usability compared to the DRM structure of exiting portable digital audio device.

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The Method for Online Estimating Utilization Rate of Motorway Service Area Under the V2I Data Condition (V2I 데이터 Online 고속도로 휴게소 이용률 추정 방법)

  • Chang, Hyunho;Lee, Jinsoo;Yoon, Byoungjo
    • Journal of the Society of Disaster Information
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    • v.15 no.4
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    • pp.548-559
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    • 2019
  • Purpose: Analysis method of V2I data driven motorway service area usage behavior to cope with manpower survey. Method: Segmentation of traveling state group and boundary using the distribution characteristics of traveling speed data of individual vehicles. Result: As a result of the verification, the use rate of resting places in lunchtime surged, and the boundary between the distribution status of the traffic speed data was clearly or unclear. Conclusion: The effect of the cost reduction is big because it can cope with the use of rest area survey by manpower and there is no limit in the time and space range of investigation. The dynamic utilization rate of each time sequence, such as a service area/drowsiness shelter/simple service area, with a V2I system, can be calculated. Identify illegal parking on highway section. Identify the unexpected situation in the road section. Identify the real-time service area utilization rate and congestion information.

A study on the activation plan of domestic franchise companies third party logistics (국내 프랜차이즈 기업의 제3자 물류 활성화에 관한 연구 : 본아이에프 사례 중심으로)

  • Cho, Jun-ho;Lee, Sang-Youn
    • The Journal of Industrial Distribution & Business
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    • v.2 no.2
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    • pp.15-24
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    • 2011
  • Modern enterprises should concentrate their efforts on continuous improvements in focusing their development in the core areas of business and to reduce their expenses and to enhance the quality of service for customers. The enterprises should focus on their core business while outsourcing the non-core areas of business to external specialists for the purpose of reducing cost. In South Korea, the enterprises are becoming increasingly interested in outsourcing their logistics function, especially in using IT technologies to the 3PL. The underlying reason for this trend is because the logistics costs of Korean businesses are much higher than that of other advanced countries. This higher logistic costs weakens the price competitiveness of Korean companies in the overseas export markets and even dampening the balance of international trade. Domestically, the higher logistics costs have the effect of raising prices in the local markets and thus affecting the local economy. Therefore a solution is urgently needed to save the logistics costs for the Korean companies in the interest of increasing national competitiveness. Outsourcing to the 3PL is becoming an attraction solution to this problem. Thanks to the increasing supply of professional logistics companies, many of the enterprises are switching to the Third Party Logistics. Nevertheless the enterprises do not yet utilize the integrated third-party logistics services on a full scale. This study analyzes present conditions and problems of the domestic third-party logistics market and suggests directions for future development. To solve the problems in the domestic third-party logistics market, four actions are recommended. First there should be new supporting policies in the laws and regulations and a system for small and medium sized companies to grow. Solutions to structural problems such as abnormal multilevel merchandising, illegal operation of private cars, and freight dumping should be implemented concurrently. Furthermore, standards for new companies entry into the market should be enhanced to allow only the competitive distribution companies to enter the market. Second, development of variety of educational programs is needed through establishing human-resource development system and specialized formal educational institution focused on this market. Third, the third party distribution companies, which seek long-term relationships with the owners of goods, should endeavor to strengthen their communications capability. Fourth, adoption of high-tech distribution system and the advent of U-Logistics, making use of RFID is urgent. This study has the limitation of objectivity because it does not include various comparative case studies about companies relating to the Third Party Logistics and domestic franchise companies. However, this study is significant to the extent that it analyzes the general present conditions and the problems of domestic Third Party Logistics and suggests recommendations for revitalization of Third Party Logistics. For future studies, analyzing the successful cases of international third party logistics companies' empirical data and studying the application into domestic franchise companies would improve the objectivity of the results. This would assist the domestic third party logistics companies not only to perform excellent domestic logistics function but also to enter into the global market for international logistics.

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The Study Of Development Plan Based On The Analysis of the Import & Export Market In Korean Webtoon (한국웹툰의 수출입 시장분석을 통한 발전방안 연구)

  • Ryu, Yu-Hee;Lee, Seung-Jin
    • Cartoon and Animation Studies
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    • s.42
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    • pp.105-123
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    • 2016
  • The webtoon market has been consisently developing in the digital market. Under such circumstances, The Korea webtoon market is rapidly growing and leading of them. This is the time to prepare the base of a stable environment for the webtoon market which shows a swift rise. The Korean webtoon is surely aiming at the global market as well as the domestic one. As the Korean webtoon companies spread out to the world briskly, The leading publication cartoon market, Japan tries to break into the Korean digital market. The domestic market that has the good-quality cartoons through exportation and importation to make people of all ages enjoy them. and also the Korean webtoon is in the center of the global webtoon markert. The early model of Korean webtoon, line-webtoon is translated in English, Chinese, Thai language and Indonesian language to use on the mobile applications and web. Nevertheless, It is just the stating point. With Eradicating of the Achilles heel of the digital contents, illegal distribution and finding materials for cultural discount rate minimized cartoon, The Korean webtoon can become the highest in the global market and hold it. Moreover, not only webtoon but also published cartoons are existing together to have a long run. Beyond the existing cartoon books printed on paper, we should reach toward the digital books with portability and economic feasibility to make the contents stay out longer.

Research on Measures to Enhance Railroad Security Checks of Railroad Police Officers to Prevent Terrorist Attacks (철도테러 예방을 위한 철도경찰 보안검색 강화 방안 연구)

  • Gwon, Hyeon-Shik
    • Korean Security Journal
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    • no.49
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    • pp.157-183
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    • 2016
  • Countries across the globe, including those in Europe, are waging a "war against terrorism" as international terrorist groups such as ISIS and lone-wolf terrorists have unleashed various large-scale attacks on rail infrastructure. Anti-South Korean sentiment exists in Muslim-majority countries because the nation has cooperated with the US for its military interventions in the Middle East, and ISIS has threatened to target South Korea four times since September 9, 2015. In addition, North Korea has been left isolated in the international community with its missile and nuclear tests, while further escalating inter-Korean tension and threatening to strike major facilities and attack important figures in the South. These situations imply that South Korea is no longer immune to terrorist attacks. If the nation fails to prevent or deter such terrorist attacks against rail networks, massive casualties, property damage and social confusion would be unavoidable, deteriorating national and international trust in its counter-terrorism policies. This may lead to a national crisis involving decreases in the number of tourists, dampened interest of foreign investors, and capital flight. This study aims to propose policy measures to enhance railroad security checks, based on the work of railroad police officers, for the sake of protecting citizens and public safety. The suggestions include an incremental expansion of railroad security checks; growth of the railroad police force and adjustment of their policing distribution with other police officers; enhancement of security systems across important rail networks; improvement of the Railroad Safety Act; Southeast Asia, including the corresponding strengthening of the national crackdown illegal immigrants, and plans for pre-emptive and regular cooperation among organizations related to the promotion of security checks and the prevention of terrorist attacks.

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A Study on the Design of Smart Contracts mechanism based on the Blockchain for anti-money laundering (자금 세탁 방지를 위한 블록체인 기반 스마트 컨트랙트 메커니즘 설계)

  • Kang, Heejung;Kim, Hye Ri;Hong, Seng-phil
    • Journal of Internet Computing and Services
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    • v.19 no.5
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    • pp.1-11
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    • 2018
  • The Blockchain is a technique that prevents data from being manipulated and guarantees the integrity and reliability of the data by all participants in the network jointly owning and validating the data. Since the Blockchain characterized by security, scalability and transparency, it is used in a variety of fields including logistics, distribution, IoT and healthcare, including remittance. In particular, there is a growing interest in smart contract that can create different forms of contracts and automate implementation based on Blockchain. Smart Contract can be used to pre-programme contracts and are implemented immediately when conditions are met. As a result, digital data can be more reliable. In this paper, we are conducting a study on the smart contract design as a way to solve such problems as illegal misuse of funds on virtual currency, which has become an issue recently. Through this process, we applied the customer identification and money laundering prevention process using smart contract, and then check the possibility of preventing money laundering and propose the ASM (AML SmartContract Mechant) design.

An eBook Service System based on VOD Broadcasting Contents of Smart TV (스마트 TV의 VOD 방송 콘텐츠 기반 전자책 서비스 시스템 개발)

  • Jun, Eung Sup;Chang, Yong Sik
    • Journal of the Korea Society of Computer and Information
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    • v.19 no.12
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    • pp.257-266
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    • 2014
  • In this paper, we propose the development of an eBook Service System based on VOD Broadcasting Contents(eBSS-VOD) which protects the illegal copy through the effective DRM strategy. Here, eBSS-VOD is composed of three sub-systems - eBook server management system, ePub Builder, and eBook App - according to the functional points of view. The eBook server management system operates to manage the eBooks, the encription keys, the VOD contents, the membership and the history of users' viewing log. The ePub Builder assists to produce eBooks by DRM strategy. The eBook App provides users with the utility services of VOD viewing and eBook purchase processing. The proposed eBSS-VOD, differently from the current eBook systems, helps to increase the users' interests in reading books and to motivate the users' purchasing needs and it also makes new distribution channel for eBooks based on VOD broadcasting contents through smart applications. We provides the differentiated eBook builder which are based on ePub3.0 and DRM strategy. Through empirical survey results on users' interests and purchase intention for eBooks, we show that the proposed eBSS-VOD has the comparative effects compared to the current systems.