• Title/Summary/Keyword: IkB

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Influence of Boron Content on the Thermoelectric Properties of p-type Si0.8Ge0.2 Alloy (Si0.8Ge0.2계 합금에서 열전특성에 미치는 B의 영향)

  • Hwang, Sung-Doo;Choi, Woo-Suk;Park, Ik-Min;Park, Yong-Ho
    • Journal of Powder Materials
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    • v.14 no.4
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    • pp.272-276
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    • 2007
  • P-type thermoelectric material $Si_{0.8}Ge_{0.2}$ was sintered by Hot Press process (HP) and the effect of boron ($0.25{\sim}2$ at%) addition on the thermoelectric properties were reported. To enhance the thermoelectric performances, the $Si_{0.8}Ge_{0.2}$, alloys were fabricated by mechanical alloying (MA) and HP. The carrier of p-type SiGe alloy was controlled by B-doping. The effect of sintering condition and thermoelectric properties were investigated. B-doped SiGe alloys exhibited positive seebeck coefficient. The electrical conductivity and thermal conductivity were increased at the small amount of boron content ($0.25{\sim}0.5$ at%). However, they were decreased over 0.5 at% boron content. As a result, the small addition of boron improved the Z value. The Z value of 0.5 at% B doped $Si_{0.8}Ge_{0.2}$ B alloy was $0.9{\times}10{-4}/K$, the highest value among the prepared alloys.

Effect of infectious bursal disease virus infection on pathogenesis of necrotic enteritis in chicken (Infectious bursal disease virus 감염이 닭 괴사성 장염의 병원성에 미치는 영향)

  • Kim, Hong-jib;Kang, Mun-il;Chung, Un-ik
    • Korean Journal of Veterinary Research
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    • v.36 no.4
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    • pp.997-1005
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    • 1996
  • For understanding the role of infectious bursal disease virus(IBDV) to the pathogenesis of necrotic enteritis due to Clostridium perfringens(CP), all 15 day-old chickens used were divided as the following groups; A and E group with the feeding of feed contaminated with CP, B group with oral adminstration of IBDV($50{\mu}l/head$, $10^{3.4}EID_{50}$ of $P_4$ strain) and simultaneously feeding of feed contaminated with CP, C group treated with IBDV alone, F group with the feeding of feed contaminated with CP at 3 weeks after oral inoculation of IBDV, D and G group with the feeding of normal feed as controls. In mortality, B group(30%) was not a difference compared to A group(20%)(p>0.05), but in the pathological lesions the former was more severe degree than the latter. The mortality of F group(70%) was a significant difference to those of A, B or E group (20%)(p<0.01). Also, showed much F group more marked lesions than A, B or E group. In the chickens occurred the death during the study, mean concentration of CP was reached at $10^8{\sim}10^9CFU/g$ in the intestinal contents. B group showed higher mortality and more severe pathological changes than A and E group. Consequently, the results in the study were confirmed that the IBDV could be a role as a enhancing factor in pathogenesis of necrotic enteritis due to CP under the field condition.

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Synthesis of Organic-inorganic Core-shell Nanoparticle Powder using Immersion Annealing Process (담금 어닐링을 이용한 유·무기 코어-쉘 나노입자 파우더 합성법)

  • Choi, Young Joong;Jung, Hyunsung;Bang, Jiwon;Park, Woon Ik
    • Journal of the Microelectronics and Packaging Society
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    • v.25 no.4
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    • pp.35-40
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    • 2018
  • Simple and useful synthetic process to control the morphology of block copolymers (BCPs) is required for implementation in various device applications. However, the conventional method to use colloidal templates is not enough to realize the production of pure and massive core-shell nanoparticles due to the cost-intensive complex process. Here, we introduce a novel and facile synthesis method to realize the formation of core-shell $SiO_x$ nanoparticle power by employing an immersion annealing of a sphere-forming poly(styrene-b-dimethylsiloxane) (PS-b-PDMS) BCP. We successfully obtained a PS-encapsulated $SiO_x$ nanoparticle with a diameter of ~20 nm. In addition, we analyzed how the mixing ratio of heptane/ethanol affects the BCP morphology of self-assembled PS-b-PDMS nanoparticles, showing a worm-like structure under the optimum immersion conditions. This useful approach is expected to be extendable to other solvent-based BCP synthesis, providing a new guideline for unique BCP production.

Shear Strength of the ${Cu_6}{Sn_5}$-dispersed Sn-Pb Solder Bumps Fabricated by Screen Printing Process (${Cu_6}{Sn_5}$를 분산시켜 스크린 프린팅법으로 제조한 Sn-Pb 솔더범프의 전단강도)

  • Choe, Jin-Won;Lee, Gwang-Eung;Cha, Ho-Seop;O, Tae-Seong
    • Korean Journal of Materials Research
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    • v.10 no.12
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    • pp.799-806
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    • 2000
  • Cu$_{6}$Sn$_{5}$-dispersed 63Sn-37Pb solder bumps of 760$\mu\textrm{m}$ size were fabricated on Au(0.5$\mu\textrm{m}$)/Ni(5$\mu\textrm{m}$)/Cu(27$\pm$20$\mu\textrm{m}$) BGA substrates by screen printing process, and their shear strength were characterized with variations of dwell time at reflow peak temperature and aging time at 15$0^{\circ}C$ . With dwell time of 30 seconds at reflow peak temperature, the solder bumps with Cu$_{6}$Sn$_{5}$ dispersion exhibited higher shear strength than the value of the 63Sn-37Pb solder bump. With increasing the dwell time longer than 60 seconds, however the shear strength of the Cu$_{6}$Sn$_{5}$-dispersed solder bumps became lower than that the 63Sn-37Pb solder bumps. The failure surface of the solder bumps could be divided into two legions of slow crack propagation and critical crack propagation. The shear strength of the solder bumps was inversely proportional to the slow crack propagation length, regardless of the dwell time at peak temperature, aging time at 150 $^{\circ}C$ and the volume fraction of Cu$_{6}$Sn$_{5}$ dispersion.> 5/ dispersion.

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Broadband U-Shaped RFID Tag Antenna with Near-Isotropic Characteristic (광대역에서 일정한 준 등방성 특성을 가지는 U-형태의 RFID 태그 안테나)

  • Lee, Sang-Woon;Jung, Hak-Joo;Choo, Ho-Sung;Park, Ik-Mo
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.20 no.5
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    • pp.480-492
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    • 2009
  • In this paper, we proposed a broadband U-shaped RFID tag antenna with near-isotropic characteristic at UHF band. The proposed tag antenna is composed of the U-shaped half wavelength dipole and a rectangular shaped feed. The rectangular shaped feed that is located inside U-shaped dipole is connected for conjugate impedance matching with the commercial tag chip. A better constant gain deviation characteristic in the operating frequency band is achieved by inserting a rectangular slit in the lower center of the U-shaped antenna body. On the condition of VSWR<2, the tag antenna had the measured bandwidth of 10.36%, from 860.5 to 954.5 MHz, and 9.84%, from 864.5 to 954 MHz, for antenna without slit and with slit, respectively. On the condition of VSWR<5.8, the tag antennas had the measured bandwidth of 15.78%, from 835.5 to 979.5 MHz, and 15.89%, from 837 to 981.5 MHz, for antenna without slit and with slit, respectively. The difference between the maximum and minimum gain deviations of tag antenna without slit in the operating frequency band is 0.53 dB since the maximum and minimum gain deviations are 3.86 dB and 3.33 dB, respectively. Whereas the difference between the maximum and minimum gain deviations of tag antenna with slit in the operating frequency is 0.06 dB since the maximum and minimum gain deviations are 3.60 dB and 3.54 dB, respectively.

Mechanism of Anti-Invasive Action of Docosahexaenoic Acid in SW480 Human Colon Cancer Cell (인체 대장암 세포주 SW480에서 docosahexaenoic acid에 의한 침윤억제 기전)

  • Shin, So-Yeon;Kim, Yong-Jo;Song, Kyoung-Sub;Jing, Kaipeng;Kim, Na-Yeong;Jeong, So-Yeon;Park, Ji-Hoon;Seo, Kang-Sik;Heo, Jun-Young;Kwon, Hyun-Joo;Park, Jong-Il;Park, Seung-Kiel;Kweon, Gi-Ryang;Yoon, Wan-Hee;Hwang, Byung-Doo;Lim, Kyu
    • Journal of Life Science
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    • v.20 no.4
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    • pp.561-571
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    • 2010
  • Colon cancer is one of the most common malignancies in the western world and the second leading cause of cancer death in Korea. Epidemiology studies have shown a reduced incidence of colon cancer among populations consuming a large quantity of ${\omega}3$-polyunsaturated fatty acids (${\omega}3$-PUFA) of marine origin. Recently, it has been found that ${\omega}3$-PUFA has an antineoplastic effect in several cancers. This study was designed to investigate the mechanism of the anti-invasive effect of ${\omega}3$-PUFA in colon cancer. ${\omega}3$-PUFA, docosahexaenoic acids (DHA) and eicosapentaenoic acid (EPA) treatment resulted in a dose-dependent inhibition of cell growth in SW480 human colon cancer cells. In contrast, arachidonic acid (AA), a ${\omega}6$-PUFA, exhibited no significant effect. This action likely involves apoptosis, given that DHA treatment increased apoptotic cells in TUNEL assay. Moreover, invasiveness of SW480 cells was inhibited following treatment of DHA in a dose-dependent manner; in contrast, AA had no effect. The levels of MMP-9 and MMP-2 mRNA decreased after DHA pretreatment. MMP-9 and MMP-2 promoter activities were also inhibited by DHA treatment. The levels of NF-kB and p-IkB protein were down-regulated by DHA pretreatment in a dose dependent manner. In addition, DHA inhibited NF-kB promoter reporter activities. These findings suggest that ${\omega}3$-PUFA may inhibit cancer cell invasion by inhibition of MMPs via reduction of NF-kB in colon cancer. In conclusion, ${\omega}3$-PUFA could be used for chemoprevention and treatment of human colon cancer.

Effect of Bulnesia sarmienti Ethanol Extract on Plasma Levels of Glucose and Lipid in Streptozotocin Induced Diabetic Rats (Bulnesia sarmienti 에탄올 추출물이 streptozotocin 유발 당뇨 흰쥐의 혈당 및 혈장 지질수준에 미치는 영향)

  • Park, Chang-Ho;Kim, Dae-Ik;Shin, Eun-Ji;Lee, Gee-Dong;Kim, Jung-Ok;Kim, Kil-Soo;Hong, Joo-Heon
    • Korean Journal of Food Science and Technology
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    • v.40 no.4
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    • pp.455-459
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    • 2008
  • This study examined the effects of Bulnesia sarmienti ethanol extract on lipid metabolism in streptozotocin (STZ)-induced diabetic rats. Sprague Dawley rats were induced with diabetes mellitus by injecting STZ (45 mg/kg) into the tail vein, and were then divided into 5 groups: normal, STZ-control, and three experimental diabetic groups. The rats were fed a basal diet along with B. sarmienti ethanol extract for 8 weeks. According to the results, after 8 weeks of consuming the experimental diets, the body weights and food efficiency ratios of the B. sarmienti ethanol extract-fed groups were not different from those of the control group. However, the concentrations of plasma total-cholesterol, LDL-cholesterol, and triglycerides were significantly lower in the B. sarmienti ethanol extract groups as compared to those of the control group. Although a blood glucose control effect was not observed after the eight weeks of B. sarmienti ethanol extract treatment in this type-l diabetes model, it was discovered that the experimental diets were highly effective at lowering levels of serum lipids, including triglycerides, total-cholesterol, and LDL-cholesterol.

Establishment of an Antibacterial Yeast That Producing Bacteriocin Subpeptin JM4-A or Subpeptin JM4-B (박테리오신 Subpeptin JM4-A 혹은 Subpeptin JM4-B를 생산하는 항균 효모의 제작)

  • Lee, Ok-Hee;Jang, Min-Kung;Lee, Dong-Geun;Kim, In-Hae;Lee, Jae-Hwa;Ha, Jong-Myung;Ha, Bae-Jin;Ahn, Ik-Yong;Cho, Dong-In;Lee, Sang-Hyeon
    • Journal of Life Science
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    • v.18 no.2
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    • pp.287-290
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    • 2008
  • In order to obtain yeast cells producing a bacteriocin, Subpeptin JM4-A or Subpeptin JM4-B, the 48 bp oligonucleotides corresponding to Subpeptin JM4-A and Subpeptin JM4-B genes including codon for start and stop were chemically synthesized and cloned into pAUR123, an yeast expression vector. Transformed yeast cells exhibited growth inhibition of Bacillus subtilis, Escherichia coli and Pseudonomas aeruginosa. This result indicates that yeast cells producing Subpeptin JM4-A or Subpeptin JM4-B possess bacteriocidal properties against both Gram positive B. subtilis and Gram negative E. coli and P. aeruginosa cells. The recombinant yeast strains constructed in this study can be applied in the food preservative or. animal foodfeed.

Evaluation of the Anti-thrombosis Activities of the Aerial Parts of Sageretia thea (상동나무 지상부의 항혈전 활성)

  • Pyo, Su-Jin;Lee, Yun-Jin;Park, Seong-Ik;Lee, Chang-Il;Park, Jong-Yi;Sohn, Ho-Yong
    • Journal of Life Science
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    • v.30 no.5
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    • pp.443-451
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    • 2020
  • Recently, thrombotic diseases have become rapidly more prevalent due to Westernized lifestyles and high-fat diets. In this study, the anti-thrombosis activities of the aerial parts of Sageretia thea were evaluated using ethanol extracts of the leaf (ST-L), branch (ST-B), and fruit (ST-F), and their anti-coagulation, platelet aggregation inhibition, and hemolytic toxicity were assessed. In comparison to the ST-F extract, the ST-B exhibited 6.7 times more polyphenol content, and the ST-L had 2.7 times more total flavonoid content. The ST-L and ST-B extracts showed stronger inhibitions of thrombin, prothrombin, and blood coagulation factors than aspirin, berry extracts, or commercial oriental herbs. Furthermore, ST-L and ST-B showed superior platelet aggregation-inhibitory activities than aspirin. The ST-F extract demonstrated only minor anti-thrombosis effects, and none of the extracts showed hemolysis against red blood cells up to 1 mg/ml. Phenolic acid and flavonoid analysis of the ST-L and ST-B extracts showed abundant rutin, isoquercitrin, and astragalin as the major active compounds. Further research on the anti-thrombotic activity of isoquercitrin, a rare flavonoid from quercetin, is necessary. This is the first report of isoquercitrin in Sageretia thea, and our results suggest that ST-L and ST-B extracts could therefore developed as anti-thrombosis agents.

Evaluation of flood control capacity of agricultural reservoirs during flood season (홍수기 농업용 저수지의 홍수조절용량의 평가)

  • Jang, Ik Geun;Lee, Jae Yong;Lee, Jeong Beom;Kim, Jin Soo
    • Journal of The Korean Society of Agricultural Engineers
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    • v.56 no.4
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    • pp.69-75
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    • 2014
  • We investigated flood control capacity of 484 agricultural reservoirs with storage capacity of over 1 million $m^3$ in South Korea. In general, agricultural reservoir secures flood control capacity by setting up limited water level during flood season from late June to mid-September. The flood control capacity of an agricultural reservoir during flood season can be divided into stable flood control capacity during non-flood season, stable flood control capacity associated with limited water level, and unstable flood control capacity associated with limited water level. In general, the flood control capacity significantly (P < 0.001) increased with reservoir capacity irrespective of type of spillway. The unstable flood control capacity accounted for about 20 % of reservoir capacity in the uncontrolled reservoirs. The study reservoirs showed flood control capacity of 0.60-65 billion (B) $m^3$ and stable flood control capacity of 0.43-47 B $m^3$, depending on the upper and lower limited water levels during the flood season. The stable flood control capacity of the gated reservoirs (0.29-0.33 B $m^3$) was about two times than that of reservoirs with uncontrolled spillways (0.14 B $m^3$). The ratios of stable flood control capacity to reservoir capacity for agricultural reservoirs range from 21 to 23 %, similar to that for Daecheong multipurpose dam. Moreover, the reservoirs with over 100 mm ratio of flood control capacity to watershed area accounted for 38 % of total gated reservoirs. The results indicate that many agricultural reservoirs may contribute to controlling flood in the small watersheds during the flood season.