• 천문학회보
• /
• 제42권2호
• /
• pp.75.1-75.1
• /
• 2017

Ram pressure due to the intracluster medium (ICM) is known to play a crucial role in removing the cool gas content of a galaxy on a short timescale, potentially driving a star forming galaxy to evolve into a red passive population. Although many HI imaging studies find clear evidence of diffuse atomic gas stripping from cluster galaxies, it is still debatable whether the ram pressure can also strip dense molecular gas. NGC 4522, a Virgo spiral, undergoing strong ram pressure stripping, is one of the few cases where extraplanar CO emission together with stripped HI gas and $H{\alpha}$ knots has been identified, providing an ideal laboratory to study the molecular gas stripping event and the extraplanar star formation activity. The aim of this work is to investigate the origin of extraplanar molecular clouds near NGC 4522 (e.g. stripped or forming in situ), and to probe a relation between the molecular gas surface density and the star formation rate (i.e. the Kennicutt-Schmidt law) at sub-kpc scale, especially in the extraplanar space, using ALMA Cycle 3 CO data and $H{\alpha}$ data of NGC 4522. We present the results from our ALMA observations, and discuss possible scenarios for the origin of extraplanar molecular clouds and to characterize the star formation activity associated with stripped gas outside the galactic disk.

• Asian Pacific Journal of Cancer Prevention
• /
• 제17권7호
• /
• pp.3025-3033
• /
• 2016

Chronic myeloid leukaemia (CML) is a clonal myeloproliferative hematopoietic stem cell disorder. Deregulated BCR-ABL fusion tyrosine kinase activity is the main cause of CML disease pathogenesis, making BCR-ABL an ideal target for inhibition. Current tyrosine kinase inhibitors (TKIs) designed to inhibit BCR-ABL oncoprotein activity, have completely transformed the prognosis of CML. Interruption of TKI treatment leads to minimal residual disease reside (MRD), thought to reside in TKI-insensitive leukaemia stem cells which remain a potential reservoir for disease relapse. This highlights the need to develop new therapeutic strategies for CML either as small molecule master TKIs or phytopharmaceuticals derived from nature to achieve chronic molecular remission. This review outlines the past, present and future therapeutic approaches for CML including coverage of relevant mechanisms, whether ABL dependent or independent, and epigenetic factors responsible for developing resistance against TKIs. Appearance of mutant clones along the course of therapy either pre-existing or induced due to therapy is still a challenge for the clinician. A proposed in-vitro model of generating colony forming units from CML stem cells derived from diagnostic samples seems to be achievable in the era of high throughput technology which can take care of single cell genomic profiling.

• 천문학회보
• /
• 제36권2호
• /
• pp.142.1-142.1
• /
• 2011

UBVI and $H{\alpha}$ CCD photometry of IC 1848, one of active star-forming regions in Cas OB6, is carried out as a part of Sejong Open cluster Survey (SOS) project. An OB association is an ideal laboratory for studying the triggered star formation and star formation history. Our purposes are to provide deep photometric data up to 21 mag in V and physical parameters of IC 1848. We classify 79 early-type stars and 186 pre-main sequence (PMS) stars as being the members of the cluster using photometric criteria. The IR excess emission PMS stars by Koenig et al. (2008) are also included as members of IC 1848. Total number of members is 414. We derive the interstellar reddening (=$0.659{\pm}0.058$ mag), reddening law ($R_V=4.0{\pm}0.1$), distance modulus ($V_0-M_V=12.0{\pm}0.1$ mag) using the early-type members of IC 1848. We also determine the age of the cluster ($3.5{\pm}1.5$ Myr) by placing the theoretical isochrones on the HR diagram.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2009년도 제38회 동계학술대회 초록집
• /
• pp.9-10
• /
• 2010

Since the discovery of graphene by mechanical exfoliation from graphite[1], various fabrication methods are available today such as chemical exfoliation, epitaxial graphene on SiC substrates, etc. In view of industrialization, the mechanical exfoliation method may not be an option. Epitaxial graphene on SiC substrates, in this respect, is by far more practical because the method consists of conventional thermal treatments familiar to semiconductor industry. Still, the use of the SiC substrate itself, and hence the incompatibility with the Si technology, lessens the importance of this technology in its future industrialization. In this context, we have tackled the problem of forming graphene on Si substrates (GOS). Our strategy is to form an ultrathin (~80 nm) SiC layer on top of a Si substrate, and to graphitize the top SiC layers by a vacuum annealing. We have actually succeeded in forming the GOS structure [2,3,4]. Raman-scattering microscopy indicates presence of few-layer graphene (FLG) formed on our annealed SiC/Si heterostructure, with the G ($1580\;cm^{-1}$) and the G'($2700\;cm^{-1}$) bands, both related to ideal graphene, clearly observed. Presence of the D ($1350\;cm^{-1}$) band indicates presence of defects in our GOS films, whose elimination remains as a challenge in the future. To obtain qualified graphene films on Si substrate, formation of qualified SiC films is crucial in the first place, and is achieved by tuning the growth parameters into a process window[5]. With a potential for forming graphene films on large-scale Si wafers, GOS is a powerful candidate as a key technology in bringing graphene into silicon technology.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• 제30권1호
• /
• pp.17-24
• /
• 2004

The purpose of this study was to evaluate the stability and efficacy of biologic membrane made of freeze-dried cartilage as a barrier to facilitate guided bone regeneration in experimental non-healing bone defects in the rat mandible. Nine adult Sprague-Dawley rats (400-500g) were used in experiment. 5.0mm in diameter were created on the mandibular angle area by means of slow-speed trephine drill. In microscopic examination, dynamic immature bone forming at 2 weeks and its calcification at 4 weeks were observed. The membrane made of lyophilized cartilage taken from human costal cartilage seems to be very effective for guided bone regeneration as a biologic membrane and the scaffold for attachment of cells or local drug delivery system of growth factor, which may meet the ideal requirement of a barrier membrane and graft materials.

• 한국정보보호학회:학술대회논문집
• /
• 한국정보보호학회 2006년도 하계학술대회
• /
• pp.219-222
• /
• 2006

In this paper an intrusion detection system technique of wireless Ad Hoc network is explained and the advantage of making them work in IEEE 802.15.4/ZigBee wireless standard is also discussed. The methodology that is mentioned here is intrusion detection architecture based on a local intrusion database [1]. An ad hoc network is a collection of nodes that is connected through a wireless medium forming rapidly changing topologies. Due to increased connectivity (especially on the Internet), and the vast spectrum of financial possibilities that are opening up, more and more systems are subject to attack by intruders. An ideal IDS should able to detect an anomaly caused by the intruders quickly so that the misbehaving node/nodes can be identified and appropriate actions (e.g. punish or avoid misbehaving nodes) can be taken so that further damage to the network is minimized

• 유체기계공업학회:학술대회논문집
• /
• 유체기계공업학회 2006년 제4회 한국유체공학학술대회 논문집
• /
• pp.345-348
• /
• 2006

In sheet metal forming process using press and draw die some defect can be made because of the high pressure of air pocket between draw die and the product. The purpose of this study is to develop a program to decide an optimal combination of air vent hole size and number to prevent those defect on product. The air inside air pocket is considered as ideal gas and the compression and expansion is assumed as isentropic process. The mass flow is computed in two flow condition: unchocked and chocked condition. The present computation obtains required cross-sectional area of air vent hole for not exceeding the user specified pressure such as the pressure for yielding strength of the product or the pressure for unchocked flow. To validate the program the present results are compared with the results of other researchers and commercial CFD code.

• 한국표면공학회지
• /
• 제23권4호
• /
• pp.197-207
• /
• 1990

Atomic layer epitaxy is a relatively new epitaxial pprocess chracterized by the alternate and separate exposure of a susbstrate surface to the reactants contaning the constituent element of a compound semicoductror. The ideal ALE is expected to provide sevral advantageous as petcts for growing complicated heterostrutures such as relativly easy controls of the layer thinkness down to a monolayer and in forming abrupt heterointerfaces though monolayer self-saturatio of the growth. In addition, since ALE is stongly dependent on the surface reaction, the growth can also be controlled by photo-excitation which provides activation can be energies for each step of the reaction paths. The local growth acceleration by photo-excitation can be exploited for growing several device strures on the same wafer, which provides another important practical advantage. The ALE growth of GaAs has advanced to the point the laser opertion has been achieved from AlGs/GaAs quantun well structures where thee active layers were grown by thermal and Ar-laser assisted ALE. The status of the ALE growth of GaAs and other III-V compounds will be reviewed with respect to the growth saturation behavior and the electrical properties of the grown crystals.

• International Journal of Computer Science & Network Security
• /
• 제23권7호
• /
• pp.193-201
• /
• 2023

Abstraction is the cornerstone of ideal software engineering (SWE). This paper discusses a problem of forming reasonable generalizations, representations and descriptions in various software development processes through the prism of poor-quality (rash, unconsidered, uncertain and harmful) abstractions. To do this, emphasis is made on an induced strategic connection between the required abstraction and its compact specific formulation based on existing research and the author's introspective experience. A software aim point and characteristic preservation of the solution integrity is the subject of the best formulation and a program module or code associated with it. Moreover, a personal attitude expressed by personal interest, motivation and creativity, is proclaimed to be a fundamental factor in successful software development.

• 대순사상논총
• /
• 제24_2집
• /
• pp.85-115
• /
• 2015

The Reordering of the Universe(天地公事) pursuing the Latter world(後天)'s ideal world while denying the Former world(先天) is composed of enormous rituals. The Dosu(度數) is formed through these rituals and the world is transformed according to the Dosu. The people who follow the Sangje(上帝), the subject of this universe reordering and also participate in the Reordering of the Universe are called as the followers. The follower group can be said as a ritual group in the aspect that they participate in the ritual for the Reordering of the Universe. They not only observed the rituals but also actively participated in them, so took certain roles in forming the Dosu. That is, they performed certain, given roles in developing the rituals, or actively proposed their ideas under the Sangje's leadership, and participated in the process realizing the Dosu. Therefore it can be said that they were a group initiatively participating in the process overcoming the Former world's Sangguk(相克) world, and making the latter world's ideal world. It seemed that the followers at that time might have gone through a certain entrance ritual process in order to join in such a follower group. The 『Jeon-Gyeong』 recorded the entrance rituals of a man called as Cha Gyeong Seok among tremendous followers relatively in detail. According to the 『Jeon-Gyeong』, he first had to get a unique test in the entrance process, and the test was proceeded in several stages: the wisdom test reflecting the Sangje's unusual intelligence, the patience test to endure physical, psychological pains for the great ethic, and the test to evaluate the testee's ability to give up past oneself and to follow the Sangje with a new body & mind. In the process separating himself from the past his appearance, Gyeong-Seok, the candidate to enter, faced a liminal situation, and then performed the incorporation rite. In this process, the purification rite going him out of the past relationship of benefits & grudges was performed, and he was given the regulations to comply as a member of the follower group. Through such serial processes, his entrance in the follower group was allowed. What requested to the candidate in this entrance process was the severance from one's past. For that, the candidate was needed to go out of his past life habits, to free from the relationship of benefits and grudges, and to sever him from his past faults. Such severance was the precondition for him to go out of the Former world's negative reality and to break from the Sanggeuk habits. Another thing requesting to the candidate as well as the severance from his past was to establish a new ideal. The new ideal should be matched with the ideal of the Reordering of the Universe whose main ideology was the Haewon-Sangsaeng(解冤相生). Such ideal can be said as the driving force to proceed toward the new ideal world of Latter World. And the candidate was requested to purify his mind and to participate in the Universe Fair Judgement (天地公庭). That can be said as an important condition for the new member directly to participate in the ritual of the Reordering of the Universe dramatically transforming the world. Finally, the candidate was given the regulations for his ascetic practice(修道) as well as his participation in the Reordering, and was requested to comply them. After becoming a member of this follower group, one had to practice his asceticism through the compliance with such regulations and the training of mantras(呪文) in order to accomplish the goal called as Dotong(道通). By fulfilling these requirements, the newly entered member could have the qualification to perform a certain role in the ritual of the Reordering of the Universe, and could accomplish his religious ideal.