• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2006.05a
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• pp.1198-1201
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• 2006

ISO 140-1 recommends installing diffusing elements in the room if there are large variations of the sound pressure level caused by strong standing wave. Also it requires that reverberation time should not be long or short. In accordance to this regulation, we adjusted the reverberation time in the range of $1{\sim}2$ sec by using 4 types of diffusing elements. This paper demonstrates how to balance the reverberation time in the range of $1{\sim}2$ sec by using several types of diffusing elements.

• Transactions of the Korean Society of Automotive Engineers
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• v.7 no.8
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• pp.160-171
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• 1999

The paper examines the ride performance enhancement that can be obtained by applying hydraulic semiactive vibration absorbers(SAVa) to alter the compliance characteristics of the seat/wheel suspension system. The work relies on a consistent model of the (nonlinear) hydrodynamics of the SAVA. A recently developed Lyapunov control scheme is used to provide regulation.. The performance is first examined assuming a quarter car with a seat/seat mounted mass. The paper then employs a quarter car/seat with a two mass ISO model of the seated human . The simulated results indicated that a reduction of 45% of the peak vertical acceleration is achievable with new system.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.32 no.4
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• pp.393-401
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• 2022

Objectives: OHSMS, which was introduced by Serious Accident Punishment Act as a means for safety and health management at work place, but it is not effective according to recent statistical data. Therefore, I intend to compare the OHSMS regulations of SAPA based on ISO 45001, the international standard of OHSMS, and examine the differences and problems. Methods: The OHSMS regulation of Serious Accident Punishment Act was compared and analyzed using the content standard of ISO 45001, the international standard of OHSMS. The construction and operation aspects and differences in key concept definitions of OHSMS were analyzed in depth. Results: ISO 45001 aims to provide OHSMS with an autonomous framework to manage risks and opportunities in safety and health management, whereas Serious Accident Punishment Act aims for safety and health management through an interest and effort in safety and health management on the premise of legal responsibilities of corporations and CEO. As a result, comparing to ISO 45001 in construction and operation aspects and differences in key concept definitions of OHSMS, the OHSMS of Serious Accident Punishment Act do not cover the entire business in concept definition and construction. Conclusions: In order for Serious Accident Punishment Act to achieve its original purpose of preventing serious accidents through systemic safety and health management, it is necessary to correctly understand the contents of ISO 45001 and to revise the OHSMS regulations in a direction that can ensure predictability and feasibility.

• Nutritional Sciences
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• v.9 no.4
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• pp.240-247
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• 2006

In this study we investigated the neuroprotective, antioxidative, and hypocholestrolemic effects of dietary soy protein and soy isoflavone in a rat focal brain ischemia model. Weaning Sprague-Dawley rats were fed a 20% casein-based diet (CA), 20% soy protein-based diet (SP), or 0.2% soy isoflavones-supplemented diet (ISO) for 6 weeks. The cortical infarction volume of the ISO group was significantly lower than that of the SP group. The thiobarbituric acid reactive substances (TBARS) were considerably lower in the ISO group than the CA group. Glutatbione peroxidase activities of the SP group were notably higher than those of the CA group. Acetylcholinesterase (AchE) activities of the SP group were significantly decreased compared to the CA group. LDL cholesterol levels and LDL/HDL ratios of the ISO group were lower than those of the CA and SP groups. Our results collectively suggest that soy isoflavones may contribute to neuroprotection by reducing the TBARS and serum LDL/HDL ratio, whereas soy protein may be associated with the regulation of cognitive functions by modulating AchE activity.

• Journal of Biomedical Engineering Research
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• v.44 no.1
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• pp.19-24
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• 2023

Due to the spread of COVID-19, many patients with severe respiratory diseases have occurred worldwide, and accordingly, the use of mechanical ventilators has exploded. However, hospitals do not have systematic risk management, and the Medical Device Regulation also provides medical device risk management standards for manufacturers, but does not apply to devices in use. In this paper, we applied the Failure Mode Effects Analysis (FMEA) risk analysis technique based on the International Standard ISO 14971 (Medical Devices-Application of risk management to medical devices) for 85 mechanical ventilators of a specific model in use in hospitals. Failure modes and effects of each parts were investigated, and risk priority was derived through multiplication of each score by preparing criteria for severity, occurrence, and detection for each failure mode. As a result, it was confirmed that the microprocessor-based Patient Unit/Monitoring board in charge of monitoring scored the highest score with 36 points, and that reliability management is possible through systematic risk management according to priority.

• The Journal of Korea Robotics Society
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• v.14 no.4
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• pp.333-339
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• 2019

Cobots are industrial robots with greatly enhanced safety functions that enable them to work in the same space with workers without protector. Cobots are regulated by the Industrial Safety and Health Act and must be certified according to the manufacturing stage, installation stage and usage stage. The ISO 10218-2 standard applied in the installation phase is difficult to apply in the field. Therefore, it is necessary to develop a risk assessment method based on ISO 12100 standard. This paper proposes a new methodology that combines 'JSA' and 'What-if', which reflects the human error and the lack of known risk factors. Accordingly, a new risk assessment template was proposed and the effectiveness of the developed new template was examined. The current cobot safety regulations need to be unified with safety inspections scheme, and robot safety experts and infrastructures need to be expanded and Robot safety regulations should be unified to 'Robot Act'. Based on this research, risk assessment methods suitable for the field need to be developed additionally, and robot safety regulation needs to be transformed to promote the industry.

• Journal of the Korean Society of Marine Environment & Safety
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• v.13 no.4
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• pp.107-112
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• 2007

The vibration generated on shipboard is very important because it greatly affects on the comfortable mind of passenger and working conditions of crews. Shipboard vibration is closely concerned with the development of propulsion method and the type of main engine to decide speed of ship. To make the propulsion power, the main engine of ship have continuous explosion process in engine room, so the shipboard vibration is generated. The shipboard vibration causes the physiological and psychological damages to human body. In the case of the human body exposed to the shipboard vibration, the evaluation of human exposure to whole-body vibration is prescribed in ISO 6954 : 2000(E). In this paper, to evaluate the shipboard working environment, two kinds of vibration levels onboard ship were measured and compared with one another between engine rooms, engine control rooms and wheel house by the regulation of ISO 6954 : 2000(E).

• Journal of KIISE
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• v.41 no.9
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• pp.625-632
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• 2014

With the trend of increasing needs for high-technology from customer and tightening regulation on automotive fuel efficiency and safety, application of E/E system has been expanding consistently in automotive industry. Thus, demand for core elements of E/E system has been growing: micro controller, analog IC and ASIC. But, development process of automotive semiconductor hasn't been clearly established in domestic area. This research aims to present a guide and an example for construction of requirement and design development process on semiconductor based on ISO/TS 16949 that is requirement for quality management system, CMMI that has been proven in various area and ISO 26262 widely used methodology for functional safety. It is expected that the result of this research is used as guidance for construction of semiconductor development process.

• International Journal of Computer Science & Network Security
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• v.23 no.10
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• pp.57-66
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• 2023

Since 2009, Morocco has had a law governing the processing of personal data, the law 09-08, and a supervisory authority, the CNDP (National Commission for the Protection of Personal Data). Since May 2018, the European General Regulation on the Protection of Personal Data (GDPR) entered into force, which applies outside the EU in certain cases and therefore to certain Moroccan companies. The question of the protection of personal data is primarily addressed to the customer. The latter may not only be a victim of crime linked to ICT, but also have to face risks linked to the collection and abusive processing of his personal data by the private and public sectors. Often the customer does not really know how their data is stored, nor for how long and for what purpose. This fact raises the question of satisfying customer requirements, in particular for organizations that have adopted a quality approach based on ISO 9001 standard.In order to master these constraints, Moroccan companies have to adopt strategies based on modern quality management techniques, especially the adoption of principles issued from the international standard ISO 9001 while being confirmed by the law 09-08. It is through ISO 9001 and the law 09-08 that these companies can refer to recognized approaches in terms of quality and compliance. The major challenge for these companies is to have a Quality approach that allows the coexistence between the law 09-08 and ISO 9001 standard and this article deals within this specific context.

• The Korean Journal of Physiology and Pharmacology
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• v.27 no.1
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• pp.75-84
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• 2023

This study aimed to observe the protective effect of momordicine I, a triterpenoid compound extracted from momordica charantia L., on isoproterenol (ISO)-induced hypertrophy in rat H9c2 cardiomyocytes and investigate its potential mechanism. Treatment with 10 μM ISO induced cardiomyocyte hypertrophy as evidenced by increased cell surface area and protein content as well as pronounced upregulation of fetal genes including atrial natriuretic peptide, βmyosin heavy chain, and α-skeletal actin; however, those responses were markedly attenuated by treatment with 12.5 ㎍/ml momordicine I. Transcriptome experiment results showed that there were 381 and 447 differentially expressed genes expressed in comparisons of model/control and momordicine I intervention/model, respectively. GO enrichment analysis suggested that the anti-cardiomyocyte hypertrophic effect of momordicine I may be mainly associated with the regulation of metabolic processes. Based on our transcriptome experiment results as well as literature reports, we selected glycerophospholipid metabolizing enzymes group VI phospholipase A₂ (PLA2G6) and diacylglycerol kinase ζ (DGK-ζ) as targets to further explore the potential mechanism through which momordicine I inhibited ISO-induced cardiomyocyte hypertrophy. Our results demonstrated that momordicine I inhibited ISO-induced upregulations of mRNA levels and protein expressions of PLA2G6 and DGK-ζ. Collectively, momordicine I alleviated ISO-induced cardiomyocyte hypertrophy, which may be related to its inhibition of the expression of glycerophospholipid metabolizing enzymes PLA2G6 and DGK-ζ