• 한국소음진동공학회:학술대회논문집
• /
• 한국소음진동공학회 2006년도 춘계학술대회논문집
• /
• pp.1198-1201
• /
• 2006

ISO 140-1 recommends installing diffusing elements in the room if there are large variations of the sound pressure level caused by strong standing wave. Also it requires that reverberation time should not be long or short. In accordance to this regulation, we adjusted the reverberation time in the range of $1{\sim}2$ sec by using 4 types of diffusing elements. This paper demonstrates how to balance the reverberation time in the range of $1{\sim}2$ sec by using several types of diffusing elements.

• 한국자동차공학회논문집
• /
• 제7권8호
• /
• pp.160-171
• /
• 1999

The paper examines the ride performance enhancement that can be obtained by applying hydraulic semiactive vibration absorbers(SAVa) to alter the compliance characteristics of the seat/wheel suspension system. The work relies on a consistent model of the (nonlinear) hydrodynamics of the SAVA. A recently developed Lyapunov control scheme is used to provide regulation.. The performance is first examined assuming a quarter car with a seat/seat mounted mass. The paper then employs a quarter car/seat with a two mass ISO model of the seated human . The simulated results indicated that a reduction of 45% of the peak vertical acceleration is achievable with new system.

• 한국산업보건학회지
• /
• 제32권4호
• /
• pp.393-401
• /
• 2022

Objectives: OHSMS, which was introduced by Serious Accident Punishment Act as a means for safety and health management at work place, but it is not effective according to recent statistical data. Therefore, I intend to compare the OHSMS regulations of SAPA based on ISO 45001, the international standard of OHSMS, and examine the differences and problems. Methods: The OHSMS regulation of Serious Accident Punishment Act was compared and analyzed using the content standard of ISO 45001, the international standard of OHSMS. The construction and operation aspects and differences in key concept definitions of OHSMS were analyzed in depth. Results: ISO 45001 aims to provide OHSMS with an autonomous framework to manage risks and opportunities in safety and health management, whereas Serious Accident Punishment Act aims for safety and health management through an interest and effort in safety and health management on the premise of legal responsibilities of corporations and CEO. As a result, comparing to ISO 45001 in construction and operation aspects and differences in key concept definitions of OHSMS, the OHSMS of Serious Accident Punishment Act do not cover the entire business in concept definition and construction. Conclusions: In order for Serious Accident Punishment Act to achieve its original purpose of preventing serious accidents through systemic safety and health management, it is necessary to correctly understand the contents of ISO 45001 and to revise the OHSMS regulations in a direction that can ensure predictability and feasibility.

• Nutritional Sciences
• /
• 제9권4호
• /
• pp.240-247
• /
• 2006

In this study we investigated the neuroprotective, antioxidative, and hypocholestrolemic effects of dietary soy protein and soy isoflavone in a rat focal brain ischemia model. Weaning Sprague-Dawley rats were fed a 20% casein-based diet (CA), 20% soy protein-based diet (SP), or 0.2% soy isoflavones-supplemented diet (ISO) for 6 weeks. The cortical infarction volume of the ISO group was significantly lower than that of the SP group. The thiobarbituric acid reactive substances (TBARS) were considerably lower in the ISO group than the CA group. Glutatbione peroxidase activities of the SP group were notably higher than those of the CA group. Acetylcholinesterase (AchE) activities of the SP group were significantly decreased compared to the CA group. LDL cholesterol levels and LDL/HDL ratios of the ISO group were lower than those of the CA and SP groups. Our results collectively suggest that soy isoflavones may contribute to neuroprotection by reducing the TBARS and serum LDL/HDL ratio, whereas soy protein may be associated with the regulation of cognitive functions by modulating AchE activity.

• 대한의용생체공학회:의공학회지
• /
• 제44권1호
• /
• pp.19-24
• /
• 2023

Due to the spread of COVID-19, many patients with severe respiratory diseases have occurred worldwide, and accordingly, the use of mechanical ventilators has exploded. However, hospitals do not have systematic risk management, and the Medical Device Regulation also provides medical device risk management standards for manufacturers, but does not apply to devices in use. In this paper, we applied the Failure Mode Effects Analysis (FMEA) risk analysis technique based on the International Standard ISO 14971 (Medical Devices-Application of risk management to medical devices) for 85 mechanical ventilators of a specific model in use in hospitals. Failure modes and effects of each parts were investigated, and risk priority was derived through multiplication of each score by preparing criteria for severity, occurrence, and detection for each failure mode. As a result, it was confirmed that the microprocessor-based Patient Unit/Monitoring board in charge of monitoring scored the highest score with 36 points, and that reliability management is possible through systematic risk management according to priority.

• 로봇학회논문지
• /
• 제14권4호
• /
• pp.333-339
• /
• 2019

Cobots are industrial robots with greatly enhanced safety functions that enable them to work in the same space with workers without protector. Cobots are regulated by the Industrial Safety and Health Act and must be certified according to the manufacturing stage, installation stage and usage stage. The ISO 10218-2 standard applied in the installation phase is difficult to apply in the field. Therefore, it is necessary to develop a risk assessment method based on ISO 12100 standard. This paper proposes a new methodology that combines 'JSA' and 'What-if', which reflects the human error and the lack of known risk factors. Accordingly, a new risk assessment template was proposed and the effectiveness of the developed new template was examined. The current cobot safety regulations need to be unified with safety inspections scheme, and robot safety experts and infrastructures need to be expanded and Robot safety regulations should be unified to 'Robot Act'. Based on this research, risk assessment methods suitable for the field need to be developed additionally, and robot safety regulation needs to be transformed to promote the industry.

• 해양환경안전학회지
• /
• 제13권4호
• /
• pp.107-112
• /
• 2007

선박에서 발생하는 진동은 여객의 안락감을 결정하거나 승조원의 근무환경에 미치는 영향이 크므로 매우 중요하다. 선박에서 발생하는 진동은 선박의 속도를 좌우하는 추진방식의 발달과 가장 밀접한 관계가 있다. 이와 갈이 추진력을 발생하기 위하여 선박의 기관실에는 디젤엔진의 연속적인 폭발과정에서 기인하는 강력한 진동이 발생하게 된다. 진동이 인체에 미치는 피해는 생리적인 피해와 심리적인 피해로 발생하게 된다. 진동 환경에 인체가 노출되는 경우, 선내의 진동에 대한 평가는 국제표준화지침인 ISO 6954:2000(E)에 의해 정하고 있다. 본 연구에서는 선박에서 진동이 인체에 미칠 수 있는 영향을 평가하기 위해 ISO 6934:2000(E)에서 규정하는 지침에 의해 선박진동의 영향이 가장 큰 기관실, 기관제어설, 각종선실 및 선교 등에서 발생하는 진동의 크기를 측정 비교하여 평가한다.

• 정보과학회 논문지
• /
• 제41권9호
• /
• pp.625-632
• /
• 2014

차량 연비 및 안전에 대한 규제 강화와 고객의 첨단 기능 요구 증가에 따라 전자제어 시스템의 적용이 지속적으로 확대되고 있다. 전자제어 시스템의 핵심 요소인 마이크로 컨트롤러, 아날로그 IC 그리고 ASIC 등 반도체의 수요도 증가하고 있다. 하지만, 국내의 차량용 반도체 개발 프로세스는 명확한 체계가 수립되지 못한 상황이다. 본 연구에서는 품질 경영 체계 요구사항인 ISO/TS 16949, 이미 다양한 분야에서 검증된 프로세스 모델인 CMMI, 그리고 차량 분야의 기능 안전 표준으로 제정된 ISO 26262를 도입하여 반도체 사양 및 설계 개발 프로세스 수립 방안 및 예시를 제시한다. 본 연구의 결과는 조직 내 반도체 개발 프로세스 수립을 위한 가이드로 활용될 것으로 기대한다.

• International Journal of Computer Science & Network Security
• /
• 제23권10호
• /
• pp.57-66
• /
• 2023

Since 2009, Morocco has had a law governing the processing of personal data, the law 09-08, and a supervisory authority, the CNDP (National Commission for the Protection of Personal Data). Since May 2018, the European General Regulation on the Protection of Personal Data (GDPR) entered into force, which applies outside the EU in certain cases and therefore to certain Moroccan companies. The question of the protection of personal data is primarily addressed to the customer. The latter may not only be a victim of crime linked to ICT, but also have to face risks linked to the collection and abusive processing of his personal data by the private and public sectors. Often the customer does not really know how their data is stored, nor for how long and for what purpose. This fact raises the question of satisfying customer requirements, in particular for organizations that have adopted a quality approach based on ISO 9001 standard.In order to master these constraints, Moroccan companies have to adopt strategies based on modern quality management techniques, especially the adoption of principles issued from the international standard ISO 9001 while being confirmed by the law 09-08. It is through ISO 9001 and the law 09-08 that these companies can refer to recognized approaches in terms of quality and compliance. The major challenge for these companies is to have a Quality approach that allows the coexistence between the law 09-08 and ISO 9001 standard and this article deals within this specific context.

• The Korean Journal of Physiology and Pharmacology
• /
• 제27권1호
• /
• pp.75-84
• /
• 2023

This study aimed to observe the protective effect of momordicine I, a triterpenoid compound extracted from momordica charantia L., on isoproterenol (ISO)-induced hypertrophy in rat H9c2 cardiomyocytes and investigate its potential mechanism. Treatment with 10 μM ISO induced cardiomyocyte hypertrophy as evidenced by increased cell surface area and protein content as well as pronounced upregulation of fetal genes including atrial natriuretic peptide, βmyosin heavy chain, and α-skeletal actin; however, those responses were markedly attenuated by treatment with 12.5 ㎍/ml momordicine I. Transcriptome experiment results showed that there were 381 and 447 differentially expressed genes expressed in comparisons of model/control and momordicine I intervention/model, respectively. GO enrichment analysis suggested that the anti-cardiomyocyte hypertrophic effect of momordicine I may be mainly associated with the regulation of metabolic processes. Based on our transcriptome experiment results as well as literature reports, we selected glycerophospholipid metabolizing enzymes group VI phospholipase A₂ (PLA2G6) and diacylglycerol kinase ζ (DGK-ζ) as targets to further explore the potential mechanism through which momordicine I inhibited ISO-induced cardiomyocyte hypertrophy. Our results demonstrated that momordicine I inhibited ISO-induced upregulations of mRNA levels and protein expressions of PLA2G6 and DGK-ζ. Collectively, momordicine I alleviated ISO-induced cardiomyocyte hypertrophy, which may be related to its inhibition of the expression of glycerophospholipid metabolizing enzymes PLA2G6 and DGK-ζ