• Archives of Pharmacal Research
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• v.26 no.6
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• pp.482-486
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• 2003

Adult periodontitis is a multifactorial disease characterized by multple genetic and environmental factors. In view of the importance of interleukin-4 (IL-4) gene as a genetic factor for adult periodontitis, we investigated the relationship between two polymorphisms (-590 C $\rightarrow$ T polymorphism and 70 bp repeat polymorphism) of the human IL-4 gene and adult periodontitis in the Korean population. Genomic DNA was extracted from white blood cells of 32 adult periodontitis patients and 150 normal controls, respectively. There were no significant differences in the allele, genotype and haplotype distributions of two polymorph isms between normal controls and adult periodontitis group. Therefore, our results suggest that IL-4 gene locus contributes little to the interindividual susceptibility for adult periodontitis in Korean population.

• Annual Conference of KIPS
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• 2018.05a
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• pp.224-227
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• 2018

국민의 편의성과 효율성 제고를 위한 온라인 대국민 서비스가 증가함에 따라 보안 사고들이 빈번하게 일어나며, 인적작원을 통해 많은 개인정보가 유출되고 있다. 이에 따라서 정부에서 ISMS와 PIMS 인증제도를 통하여 안정성을 확보하기 위한 제도를 내놓았다. 하지만 두 가지 인증제도의 중복항목으로 담당자들의 업무 부담이 늘며 이를 통합을 발표하였다. 저자는 인증제도의 인력항목을 좀 더 효율적으로 관리 할 수 방안을 제시하고자 한다.

• Proceedings of the Safety Management and Science Conference
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• 2008.11a
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• pp.475-489
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• 2008

1987년 최초의 ISO 9000 (품질경영시스템) 패밀리 규격이 발행된 이래, 기업의 경영 시스템(Management System)의 핵심이 되는 MS 규격으로서 QMS(ISO 9001), EMS(ISO 14001), ISMS (ISO/IEC 27001) 등이 발행 또는 개정되어 왔다. 또 QMS 섹터 규격인 항공 우주 (AS/EN 9100), 의료기기 (ISO 13485), 정보통신 (TL 9000), ITSMS(ISO 20000), FSMS (ISO 22000), SCSMS (ISO 28000) 등이나 새로운 MS 규격이 되는 GHG(ISO 14064), IPOCM(ISO/PAS 22399), SR(ISO/CD 26000) 등 ISO 또는 비ISO 의 MS 규격이 차례차례로 발행 또는 개발 중에 있어 경영시스템 인증은 더욱 더 광범위해지면서 다방면화, 섹터화의 경향을 나타내고 있다. 제품 및 서비스 무역의 글로벌화, 조달 및 투자의 비 지역화, 공공 서비스에 대한 규제 철폐, 소비자 및 환경보호에 대한 공적인 요구, 테러리즘 전염병 자연적인 재앙에 대한 국제적인 연대 책임에 대한 필요성, 새로운 기술과 혁신의 전개 등이 경영 시스템 인증에 대한 요구를 증대시키고 있으며, 그 전제로서 세계적 규모로 제도의 신뢰성을 확보하는 구조의 확립 및 활동 결과의 신뢰가 보증되는 체제가 구축되어 있어야 한다. 이러한 신뢰를 바탕으로 한 제3자 인증제도는 세계경제의 원활한 발전에 중요한 과제가 되고 있다.

• Annual Conference of KIPS
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• 2009.11a
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• pp.627-628
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• 2009

기업의 정보자산에 대한 위협이 날로 증대하고 있다. 따라서 기업의 중요한 정보를 보호 및 관리하는 정보보호관리체계 (Information Security Management System; ISMS)에 대한 필요성과 중요성이 더욱 증가하고 있다. 정보보호관리체계란 조직의 주요 정보자산을 보호하기 위해 정보보호관리 절차와 과정을 체계적으로 수립하여 지속적으로 관리 운영하기 위한 종합적인 체계를 의미한다. 본 논문에서는 국내 기업의 정보보호관리체계에 대한 문제점 및 필요성 등을 분석하여 기업 내부 시스템의 보안성 향상을 위한 효율적인 정보보호관리체계 수립방안을 제안한다.

• Radiation Oncology Journal
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• v.24 no.1
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• pp.30-36
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• 2006

Purpose: It is well known from clinical experience that acute complications of chemoradiation therapy vary from patients to patients. However, there are no known factors to predict these acute complications before treatment starts. The human XRCC1 gene is known as a DNA base excision repair gene. We investigated the possibilities of XRCC1 gene polymorphisms as a predictor for the acute complications of chemoradiation therapy in colorectal cancer patients. Materials and Methods: From July 1997 to June 2003, 86 colorectal cancer patients (71 rectal cancer, 13 sigmoid colon cancer and 2 colon cancer patients) were treated with chemoradiation therapy at the Department of Radiation Oncology, Inha University Hospital. Twenty-two patients were in stage B, 50 were in stage C, 8 were in stage D and 6 patients were unresectable cases. External radiation therapy was delivered with 10MV X-ray at a 1.8 Gy fraction per day for a total dose of radiation of $30.6{\sim}59.4 Gy$ (median: 54 Gy). All the patients received 5-FU based chemotherapy regimen. We analyzed the acute complications of upper and lower gastrointestinal tract based on the RTOG complication scale. The initial and lowest WBC and platelet count were recorded during both the RT period and the whole treatment period. Allelic variants of the XRCC1 gene at codons 194, 280 and 399 were analyzed in the lymphocyte DNA by performing PCR-RFLP. Statistical analyses were carried out with the SAS (version 6.12) statistical package. Results: When all the variables were assessed on the multivariate analysis, recurrent disease revealed the factors that significantly correlated with upper gastrointestinal acute complications. Arg399Gln polymorph isms of the XRCC1 gene, the radiation dose and the frequencies of chemotherapy during radiation therapy were significantly correlated with lower gastrointestinal complications. Arg399Gln polymorph isms also affected the decrease of the WBC and platelet count during radiation therapy. Conclusion: Although the present sample size was too small for fully evaluating this hypothesis, this study suggests that Arg399Gln polymorph isms of the XRCC1 genes may be used as one of the predictors for acute complications of chemoradiation therapy in colorectal cancer patients.

• Journal of the Korean Applied Science and Technology
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• v.30 no.2
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• pp.258-263
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• 2013

New conducting polymers containing heterocyclic ring with carbazole, EDOT and benzobisthiazole were synthesized and characterized by organic spectroscopic methods. Potentiometric ion-selective membrane electrodes (ISMEs) have been extensively used for ion analysis in clinical, environmental, and industeial fields owing to its wide response range (4 to 7 orders of magnitude), no effect of sample turbidity, fast response time, and ease of miniaturization. Considerable attention has been given to alternative use of room temperature vulcanizing (RTV)-type silicone rubber(SR) owing to its strong adhesion and high thermal durability. Unfortunately, the high membrane resistance of SR-based (ISMs)(2 to 3 higher orders of magnitude compared to those of poly(vinyl chloride)(PVC)-based ones) has significantly restricted its application. Herein we demonstrate a new method to reduce membrane resistance via addition of new conducting polymer into the SR-based ISMs.

• Cross-Cultural Studies
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• v.42
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• pp.107-129
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• 2016

In modern history, there have been several kinds of continental unions or supranational politico-economic unions in the world, such as the United Nations, the European Union, the Union of South American Nations, the African Union, etc. Modern thinkers proposed many pan-isms on their continental base, for example, Pan-Arabism, Pan-Latin Americanism, Pan-Asianism, Pan-Celtism, etc. What is the most common in these pan-isms is that a continental union would be a politico-economic system to overcome the limits of the modern state-nation and to realize a long and happy relationship between member nations and continents. However, the concept of a supranational union differs from that of cosmopolitanism, in that the former presupposes the common cultural and historical heritage in the concerned region or continent. Ngugi wa Thinog'o' Pan-Africanism implies two keywords that are connected to his concepts such as 'decentralization' and 'African languages.' Pan-Africanism supposes that Africa may gain benefits from the union of African nations under the umbrella of anti-colonial efforts to down size the Euro-American influences. Moreover, using African languages enhances self-reliance and self-imagination among the African people. For in the former colonial regimes, the European colonial languages, such as English, French, or Portuguese, were central to the dissemination of European culture and modernity. Ngugi asserts that the African peripheralized languages could reinstate the African cultural heritage and propose an alternative to the Western modernity.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.22 no.5
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• pp.1123-1132
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• 2012

Many domestic organizations are introducing and operating various information security management systems capable of coping with technical, administrative, and legal issues comprehensively and systematically, in order to prevent various infringement incidents such as personal information disclosure and hacking preemptively and actively. However, empirical analyses regarding the extent to which an information security management system contributes to information security performance have not been fully conducted, even though enterprises and organizations are actively introducing such systems in order to achieve their information security objectives as a part of their organizational management activities in line with their respective business, by investing considerable effort and resources in developing and operating these systems. This approach can be used to apply, develop, and operate the information management system actively within an organization. this study focused on analyzing how each specific phase of the information security management system affects information security performance, compared with previous studies, which generally focus on the information security control item in analyzing information security performance. The information security management system was analyzed empirically to determine how the Security PCDA cycling model affects information security performance.

• Knowledge Management Research
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• v.22 no.1
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• pp.309-330
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• 2021

The information security disclosure system (ISDS) has been implemented since 2016 to ensure the protection of stakeholders and the right to know, and to promote voluntary investment in information protection by companies. Regarding the information security disclosure system, there have been studies that urge the implementation of the system, but studies that analyze the contents disclosed after the implementation of the system or suggest improvement directions are few. In this study, the contents of the information security disclosure system that had been announced on the information security industry promotion portal until 2019 were analyzed, the current status was summarized, and the direction of system improvement was suggested. In some cases, companies that disclosed information through the disclosure system increased the number of personnel in charge and obtained certifications related to information security, but did not find any effect on the increase/decrease in investment. The current disclosure system has not been activated because it has difficulty in giving individual companies incentives to disclose. Thus, this study suggests the inclusion of ISDS to information security management system (ISMS), which is currently mandatory for certain companies. In the current disclosure system, it is difficult for the company's stakeholders or customers to check the contents of the disclosure. As a way to do this, a method of including in the contents of the personal information processing policy or the notification of the use of personal information was suggested.

• Smart Media Journal
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• v.11 no.3
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• pp.54-61
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• 2022

With the increase in the types of information systems managed by public institutions and companies, a security certification system is being implemented in Korea to quickly respond to vulnerabilities that may arise due to insufficient security checks. The korea security evaluation system, such as ISMS-P, performs a systematic security evaluation for each category by dividing the categories for technical inspection items. NIST in the United States has developed SCAP that can create security checklists and automate vulnerability checks, and the security checklists used for SCAP can be written in OVAL. Each manufacturer prepares a security check list and shares it through the SCAP community, but it's difficult to use it in Korea because it is not categorized according to the korea security evaluation system. Therefore, in this paper, we present a mechanism to categorize the OVAL definition, which is an inspection item written in OVAL, to apply SCAP to the korea security evaluation system. It was shown that 189 out of 230 items of the Red Hat 8 STIG file could be applied to the korea security evaluation system, and the statistics of the categorized Redhat definition file could be analyzed to confirm the trend of system vulnerabilities by category.