• International Journal of Advanced Culture Technology
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• 제10권2호
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• pp.220-224
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• 2022

The efficiencies of rates and energy in the fifth generation (5G) wireless channels can be improved via intelligent reflecting surface (IRS) transmissions, towards the sixth generation (6G) mobile communications. While previous works have considered mainly optimizations of IRS transmissions, we propose a performance analysis on the total power in terms of the number of reflecting devices for IRS transmissions in non-orthogonal multiple access (NOMA) networks. First, we derive an analytical expression of the total power gain factor in terms of the number of reflecting devices for the cell-edge user in IRS-NOMA systems. Then we evaluate how many reflecting devices we need to obtain a total power gain in dB. Moreover, we also demonstrate numerically the signal-to-noise ratio (SNR) gain of the IRS-NOMA system over the conventional NOMA system based on the achievable data rate.

• Asia pacific journal of information systems
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• 제13권4호
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• pp.229-255
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• 2003

This article attempts to examine the well-known law that the increasing returns to scale(IRS) is effective in the Internet business. The effect of IRS is one of the hottest issues in the Internet business sector. Many cases and survey studies support the fact that the IRS phenomenon exists in the Internet business. Executives in Internet business generally give a deep trust on this theory. As the Internet business grows, however, the boundary of the business becomes widened and complicated. And each category of Internet business is characterized with a different business style and economic behavior. It may, therefore, be dangerous to accept that the phenomenon of IRS is applied to all areas of Internet business. For this reason, the research for the close look into the IRS phenomenon should provide significant implications for the managers in the Internet business industry. This article divides the internet business into four sub-areas, and analyzes the IRS phenomenon using AHP/DEA-based full ordering technique. Interpretations are given, based upon the research results, for each sub-area of Internet business, as a guideline of setting business strategies for practical managers.

• 대한미생물학회지
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• 제35권4호
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• pp.289-297
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• 2000

Background: Staphylococcus aureus (s. aureus) and Escherichia coli (E. coli) are major pathogens in community and hospital. And they sometimes cause the outbreak in hospital in the immunocompromised patients. Pulsed-field gel electrophoresis (PFGE) has been regarded as a standard method for genotyping in epidemiologic studies, but it is laborious and time-consuming. Infrequent restriction site-polymerase chain reaction (IRS-PCR), a new genotyping methods, was performed to compare the applicability with PFGE. Methods: We performed PFGE and IRS-PCR on S. aurues (n=120) and E. coli (n=117) which were collected clinically in 4 different hospitals. We assessed each method in terms of discriminatory power, quality, and efficiency. Results: In E. coli, the discriminatory power of IRS-PCR was $46.7{\sim}86.7%$, and that of PFGE was $88.9{\sim}96.7%$ according to hospital. But in S. aurues, the discriminatory power of IRS-PCR was $20{\sim}56.7%$, and that of PFGE was $40{\sim}90%$ according to hospital. The typablity and reproducibility of IRS-PCR were 100% of each. PFGE needed four days to complete the procedure, but IRS-PCR could be performed within one day, IRS-PCR showed better resolution than PFGE. Conclusion: In case of gram negative bacteria (like E. coli), IRS-PCR could be a reliable alternative for epidemiologic typing due to better efficiency and comparable discriminatory power. But in the case of gram positive bacteria (like S. aureus), IRS-PCR does not seem to be suitable for the strain-to-strain differentiation. More trials and changes of restriction enzymes or primers could reveal the efficacy of IRS-PCR in the field of molecular typing.

• Journal of Nutrition and Health
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• 제54권6호
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• pp.603-617
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• 2021

혈당 조절에 유익한 천연 식품을 발굴하고 그 효과를 밝혀보고자 본 연구에서는 아마란스 종자에 주목하여 몇 가지 혈당조절 연관 지표의 증감 정도를 알아보았다. 아마란스 종자의 색과 발아 여부에 따라 효능에 차이가 있는지 알아보기 위하여 발아 흑색 아마란스는 germinated black amaranth (GBA), 비발아 흑색 아마란스는 black amaranth (BA), 발아 황색 아마란스는 germinated yellow amaranth (GYA), 비발아 황색 아마란스는 yellow amaranth (YA)로 구분하였고 각각의 시료는 80% 에탄올 추출물을 만들어 사용하였다. 본 연구에서 α-amylase 및 α-glucosidase 저해 활성을 측정한 결과 GBA, BA, GYA, YA 순으로 높은 저해 활성을 나타냈으며 특히 α-amylase 저해 활성 실험에서 GBA는 양성 대조물질인 acarbose와 거의 비슷한 수준을 나타내어 높은 저해 활성을 가지는 것으로 판단된다. HepG2 세포에서 포도당 흡수를 측정한 결과 모든 추출물에서 농도 의존적으로 증가하였고 GBA > BA > GYA > YA 순으로 높게 나타났다. 특히 50 ㎍/mL 농도에서 GBA는 인슐린과 유사한 값을 나타내었다. GBA를 농도별로 처리한 HepG2 세포에서 ACC, GLUT-2, GLUT-4, IRS-1, IRS-2 mRNA 발현 정도는 모두 농도 의존적으로 증가하였다. 이상의 결과로 아마란스 종자는 혈당 조절 및 개선에 효능이 있다고 평가되며 특히 발아한 흑색 종자가 혈당 조절 효능이 높게 나타남을 보여 혈당 조절에 유익한 효능을 가지는 식품 소재가 될 수 있음을 확인하였다.

• 한국측량학회지
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• 제19권4호
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• pp.373-383
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• 2001

본 연구에서는 중해상도 위성영상으로 대표적인 SPOT, 아리랑, IRS-1C위성영상에 대하여 각기 하나의 입체모델을 이용한 지도제작 실험을 수행하였으며, 각각에 대한 위치정확도, 판독 및 묘사가능한 지형지물의 분석, 기존 수치지도와의 비교 등을 통하여, 제작가능한 지도축척의 범위에 대한 기술적인 검토 및 경제성 검토를 하였다. 도화작업에 있어서, SPOT 영상은 수치입체도화기를 사용한 3차원 도화를 하였으며, 아리랑 및 IRS-lC 위성영상은 데이터에 대한 시스템 지원상의 문제가 있어서 영상정합 방법으로 수치표고모형을 생성한 후 정사보정영상을 제작하여 head-up digitizing에 의한 2차원 도화를 실시하였다. 실험 결과 중해상도 영상으로 큰 도로, 하천, 수애선 등 일부 항목에 대하여 판독과 묘사가 가능하였지만, 불가능한 항목이 많았다. 지도제작 측면에서 SPOT은 1/50,000지형도 수정용, 아리랑 및 IRS-lC는 1/25,000지형도의 수정용으로 활용이 가능하다고 판단되었다.

• Molecules and Cells
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• 제38권4호
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• pp.356-361
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• 2015

Mitochondrial dysfunction is associated with insulin resistance and diabetes. We previously showed that retinoid X receptor ${\alpha}$ ($RXR{\alpha}$) played an important role in transcriptional regulation of oxidative phosphorylation (OXPHOS) genes in cells with mitochondrial dysfunction caused by mitochondrial DNA mutation. In this study, we investigated whether mitochondrial dysfunction induced by incubation with OXPHOS inhibitors affects insulin receptor substrate 1 (IRS1) mRNA and protein levels and whether $RXR{\alpha}$ activation or overexpression can restore IRS1 expression. Both IRS1 and $RXR{\alpha}$ protein levels were significantly reduced when C2C12 myotubes were treated with the OXPHOS complex inhibitors, rotenone and antimycin A. The addition of $RXR{\alpha}$ agonists, 9-cis retinoic acid (9cRA) and LG1506, increased IRS1 transcription and protein levels and restored mitochondrial function, which ultimately improved insulin signaling. $RXR{\alpha}$ overexpression also increased IRS1 transcription and mitochondrial function. Because $RXR{\alpha}$ overexpression, knock-down, or activation by LG1506 regulated IRS1 transcription mostly independently of mitochondrial function, it is likely that $RXR{\alpha}$ directly regulates IRS1 transcription. Consistent with the hypothesis, we showed that $RXR{\alpha}$ bound to the IRS1 promoter as a heterodimer with peroxisome proliferator-activated receptor ${\delta}$ ($PPAR{\delta}$). These results suggest that $RXR{\alpha}$ overexpression or activation alleviates insulin resistance by increasing IRS1 expression.

• 천문학회보
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• 제40권2호
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• pp.42.1-42.1
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• 2015

We model the Spectral Energy Distribution (SED) of Class 0 protostar L1527 IRS using a radiative transfer code RADMC-3D. In addition to the photometry data from literatures, we include the Herschel/PACS data which well covers the far-infrared SED peak of L1527 IRS, providing precise constraints to the density structure and other physical properties of its circumstellar envelope. Previously, Tobin et al. (2013) presented a dust continuum modeling results using a rotating and infalling envelope (Terebey and Shu, & Cassen 1984 ; TSC envelope), which originally describes a power-law density profile (${\rho}{\propto}r-{\alpha}$) with the power-law index (${\alpha}$) of 1.5. However, we find that Herschel/PACS data are better fitted with a shallower power-law density profile. This smaller power-law might be attributed to a inner envelope. Thus, we fit the SED of L1527 IRS with a Bonnor-Ebert sphere, which is a combination of the inner flat-topped and the outer power-law (${\alpha}=2$) density profiles. This Bonnor-Ebert sphere is often used to explain the density profile of prestellar cores, which is considered the earliest stages of star formation. The well-fitted SED with a Bonnor-Ebert sphere suggests that L1527 IRS might have collapsed from a Bonnor-Ebert sphere rather than a singular isothermal sphere.

• ETRI Journal
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• 제45권1호
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• pp.28-44
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• 2023

We propose short packet communication in an underlay cognitive radio network assisted by an intelligent reflecting surface (IRS) composed of multiple reconfigurable reflectors. This scheme, called the IRS protocol, operates in only one time slot (TS) using the IRS. The IRS adjusts its phases to give zero received cumulative phase at the secondary destination, thereby enhancing the end-to-end signal-to-noise ratio. The transmitting power of the secondary source is optimized to simultaneously satisfy the multi-interference constraints, hardware limitations, and performance improvement. Simulation and analysis results of the average block error rates (BLERs) show that the performance can be enhanced by installing more reconfigurable reflectors, increasing the blocklength, lowering the number of required primary receivers, or sending fewer information bits. Moreover, the proposed IRS protocol always outperforms underlay relaying protocols using two TSs for data transmission, and achieves the best average BLER at identical transmission distances between the secondary source and secondary destination. The theoretical analyses are confirmed by Monte Carlo simulations.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2001년도 추계학술대회 및 정기총회
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• pp.101-101
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• 2001

In the present study, we explored to determine if insulin has any effect on the nuclear translocation of insulin receptor and tyrosine phosphoryaltion of nuclear proteins in the UMR-106 cells. Significant amount of insulin receptors and IRS-1 proteins were detected in the nucleus. IRS-1 and PI$_3$-Kinase appeared to translocate to the nucleus in a time dependent manner. Tyrosine phosphorylation of a number of proteins including 180 KDa, 85 KDa protein in the nucleus was significantly stimulated by insulin, suggesting IRS-1 and PI$_3$-Klnase was activated in the nucleus by insulin treatment. In addition, p70 S6 Kinase, a downstream target of PI3-Kinase was transiently appeared in the nucleus by insulin and its activity was stimulated by insulin. These results suggest that the insulin signaling system containing insulin receptor, IRS-1, PI$_3$-Kinase and p70 S6 Kinase operates in the nucleus of osteoblast cells. The nuclear insulin-mediated tyrosine phosphorylation may play an essential role in the gene expression, differentiation and growth of osteoblast cells.

• 대한수의학회지
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• 제49권2호
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• pp.105-111
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• 2009

In this study, occurrence of canine brucellosis was surveyed in kennels, indoor dogs and stray dogs in Korea, and infrequent restriction site-polymerase chain reaction (IRS-PCR) was applied to analyze DNA polymorphism of Brucella canis (B. canis) isolates. Among a total of 501 dogs tested, B. canis antibodies by both rapid screening agglutination with 2-mercaptoethanol (2-ME RSAT) and immunochromatographic assay were detected in only 14.1% of kennel dogs. There were no seropositive cases in indoor dogs and stray dogs. DNA polymorphism was observed in 16 B. canis isolates by the IRS-PCR. Sixteen isolates were tested with primers, PsalA, PsalC, PsalG and PsalT, and different primers produced different DNA patterns. In regard to the IRS-PCR pattern of 16 isolates, 9 (56.3%) belonged to the IRS-PCR type I. The remaining 7 were differentiated as type II, III and IV. An application of the primer PsalC provided discrimination between B. canis isolated in 2005 and others.