• Journal of Korean Medicine Rehabilitation
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• v.21 no.4
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• pp.227-239
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• 2011

Objectives: This study was performed to report the case of oriental medical treatment for the left lower limb monoplegia after herniated intervertebral disc(HIVD) operation at lumbar(L)-spine. Methods: A 38-year-old man who underwent lumbar HIVD operation at a hospital admitted with motor weakness of left lower limb, a little decreased left leg radiation pain and low back pain. We treated him by acupuncture, herbal medicine, bee venom injection moxibustion, cupping treatment physical therapy and measured with visual analogue scale(VAS), Oswestry disability index(ODI), Roland-Morris disability questionnaire(RMDO) and manual muscle test(MMT) from 8th February to 4th May 2011. Results: After treatment most symptoms decreased, VAS score changed from 10 to 3, ODI changed 71% to 37% RMDQ changed 13 to 8 and MMT changed from 3 to 5. Conclusions: Our study suggested that oriental medical treatments are significantly applicable to the monoplegia and pain after lumbar HIVD operation. And further studies ire required to identify underlying mechanism of the treatment.

• Management & Information Systems Review
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• v.31 no.4
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• pp.339-362
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• 2012

The purpose of this study is to examine the relationship between LMX, psychological empowerment and organizational commitment and the moderating effect of perceived organizational support. The research was examined using a sample of 305 employees engaged in various industries in Seoul, Gyeonggi and Gangwon provinces and the findings of these studies were as follows: To begin with, findings from the study indicate that the Leader-Member Exchange(LMX) is positively related to organizational commitment. Secondly, the Leader-Member Exchange(LMX) has been proven influential for psychological empowerment and furthermore, the results reveal that psychological empowerment(e.g. self-determination, meaning) has positive impacts on organizational commitment. Finally, it has been identified that the relationship between leader-member exchange and organizational commitment didn't prove to be moderated by perceived organizational support. The contribution and limitation of this research were discussed, and future researches were mentioned.

• Korean Journal of Microbiology
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• v.33 no.2
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• pp.157-162
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• 1997

Recently the bioremediation technology has been widely used to recover the oil contaminated environments The application of bioremediation agents to oil polluted environments became common and thus many kinds of commercial products were imported into domestic market. In Korea, howcver. the standardization of bioremediation products quality is not yet established and results of efficacy test .ire scarce. In this study five oil spill bioremediation commercial products including microbial inoculants and en'cyme agents are tested for the oil degradation rate. From the results most products shows the strong oil emulsifying phenomena due to the contained chemical oil dispersant and the low oil degradation rate. Product D inhibited the oil degradability of microorganisms even in the natural sea water. From these results it could be concluded that in the near future the laboratory protocol and standardization of products quality for bioremediarion agents should be prepared to activate the effective application of bioremediation technology in Korea.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.15 no.1
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• pp.36-43
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• 2001

Recently, outdoor lighting of buildings has bemIre activated in national level of Korea. Therefore, this study aims to analyze the outdoor ljghting effect of historic buildings with particular reference to two traditional gates architecture - Namdaemtul and Kwanghwamun For the purpose, luminance and chromaticity of outdoor lighting are measured. The results of the study are as follows; $\circled1$ Outdoor lighting of the historic buildings were mainly illuminated by the floodlights. In addition, up-lighting and accent lighting were locally used. $\circled2$ Basements and rooflines were specially emphasized, and they represented the night image of historical buildings. $\circled3$ Chromaticity distribution of historical building was wlute during the day. However, it was yellow dL1Jing the night due to the color and color temperature of outdoor lighting.ghting.

• Journal of the Korean Institute of Gas
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• v.24 no.4
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• pp.48-55
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• 2020

The installation of lightning protection system has recently been increasing, but the amount of damage has still been increasing. In this study, survey (interview) and field conditions were conducted to identify the installation and safety standards of the lightning protection system. it was analyzed that the safety management system is non-existent at the stage of the design, manufacturing and construction of the site lightning protection system, and that the safety inspection of the lightning protection facility is not properly managed. It has been shown that lightning protection systems, that can solve these problems, need to be re-established according to the reality so that safety inspection can be carried out in accordance with safety standards such as management of safety certification products, operation of survey institutions, design, manufacturing, and construction of safety standards at a national level.

• Korean Journal of Applied Biomechanics
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• v.13 no.2
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• pp.13-28
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• 2003

The purpose of this study was to analyze the kinematic characteristics of Ice hockey slap shot. The subjects of this study were four professional ice hockey players. The reflective markers were attached on the anatomical boundary line of body and the subjects were asked to perform the shot. Ariel Performance Analysis System was used to capture and digitize the shooting image, the data were analyzed by LabView 6i. The results were as fellows. 1. The period of the back swing phase was $0.542{\pm}0.062sec$, the down swing phase was $0.28{\pm}0.056sec$ and the total swing time was $0.825{\pm}0.017sec$ 2. The maximum linear velocity of the stick blade for x direction was shown after 7% of impact, for y, z direction were shown before 2%, 8% of Impact. 3. The maximum velocity of each segment for the left arm was $2.35{\pm}0.05m/s$ in the upper arm, $3.56{\pm}0.34m/s$ in the forearm, $4.75{\pm}0.67m/s$ in the hand. 4. The maximum velocity of each segment for the right arm was $4.67{\pm}0.43m/s$ in the upper arm, $7.22{\pm}0.69m/s$ in the forearm, $9.42{\pm}0.89m/s$ in the hand. 5. The angle of left elbow was generally flexed from the ready stance to the impact and was $82.26{\pm}3.45^{\circ}$ the moment of Impact. 6. The angle of the left shoulder was increased ut the down swing phase and was $78.74{\pm}4.78^{\circ}$ on the moment of impact. 7. The angle of the right shoulder was decreased in the down swing phase and increased before the impact. and the angle was $51.28{\pm}3.54^{\circ}$ on the moment of impact.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.22 no.3
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• pp.244-256
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• 2012

Objectives: This study was conducted to assess the level of depression and its association with sociodemographic characteristics and health related characteristics, job-related characteristics, sleep quality, occupational stress among manufacturing male immigrant worker in Korea. Methods: Total number of subject were 287 workers employed in 19 manufacturing industry. A structured self-administered questionnaire was used to assess each responder's sociodemographic and health related characteristics, job-related characteristics, sleep quality (PSQI), Korean occupational stress (KOSS), Depression (CES-D). The job stress questionna ire was used according to KOSS-26 and depression symptoms were measured using CES-D, which was translated into Korean. We used multiple logistic regression analysis to assess the relationship between risk factors included job stress, sleep quality and depression. Results: The prevalence of depression in survey subjects was 63.9%and poor group (PSQI) (5 point and over at PSQI score)among all subjects were 83.28%. Adjusting for confounding factor, higher the occupational stress (KOSS), depression levels were significantly higher (${\beta}=0.5575$), worse quality of sleep, the more depressed the level was slightly high ${\beta}=0.118$) did not reach statistical significance. Conclusions: The prevalence of depressive symptoms among the study subjects was higher than that among the Korean workers. Especially, the level of depression was more influenced by occupational stress than quality of sleep. Therefore, the author recommend to prepare the effective strategy for reducing the depression and also reducing the occupational stress among immigrant male workers, and the author consider that it need to support the convenient working environment such as consultation for difficulty or health care among immigrant male workers.

• Nutritional Sciences
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• v.3 no.1
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• pp.31-35
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• 2000

The purpose of this study was to compare the changes in PLP concentrations induced by regular, moderate, and abrupt, high-intensity exercise in the plasma and tissues of vitamin B6 deficient and normal rats. Forty-eight rats were fed either a vitamin B6 deficient (-B6) diet or a normal (+B6) diet for 5 weeks and were subdivided into 4 groups:non-exercise(NE) group: regular, moderate-intensity exercise (RME) group; abrupt, high-intensity exercise (AIE) group; abrupt, high-intensity exercise and recuperation(IRE) group. The RME group was exercised on treadmill ($10^{\circ}$, 0.5-0.8km/h) for 2 hours just before sacrifice at the end of 5th week on the diet and the IER group was recuperated for three days on the diet after being exercised like the AIE group. Pyridoxal 5 -phosphate(PLP) levels were compared in the plasma, liver and skeletal muscle of the rats. Plasma PLP concentration tended to decrease in -B6 rats and tended to increase in +B6 rats with AIE. Plasma PLP concentration in both +B6 rats with AIE and no change in both -B6 and +B6 rats with RME. Muscle PLP concentration decreased in +B6 rats, showed no change in -B6 rats with AIE. Muscle PLP concentrations in both +B6 and -B6 rats did not change with RME. Plasma PLP, liver PLP and muscle PLP concentration of IER returned to those of NE in both +B6 and -B6 rats. These results suggest that changes in PLP concentration in plasma, liver and muscle occur with exercise and are affected by exercise intensity and vitamin B6 status. These changes may be due to interorgan redistribution of PLP.

• Molecules and Cells
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• v.42 no.11
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• pp.783-793
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• 2019

When endoplasmic reticulum (ER) functions are perturbed, the ER induces several signaling pathways called unfolded protein response to reestablish ER homeostasis through three ER transmembrane proteins: inositol-requiring enzyme 1 (IRE1), PKR-like ER kinase (PERK), and activating transcription factor 6 (ATF6). Although it is important to measure the activity of ATF6 that can indicate the status of the ER, no specific cell-based reporter assay is currently available. Here, we report a new cell-based method for monitoring ER stress based on the cleavage of $ATF6{\alpha}$ by sequential actions of proteases at the Golgi apparatus during ER stress. A new expressing vector was constructed by using fusion gene of GAL4 DNA binding domain (GAL4DBD) and activation domain derived from herpes simplex virus VP16 protein (VP16AD) followed by a human $ATF6{\alpha}$ N-terminal deletion variant. During ER stress, the GAL4DBD-VP16AD(GV)-$hATF6{\alpha}$ deletion variant was cleaved to liberate active transcription activator encompassing GV-$hATF6{\alpha}$ fragment which could translocate into the nucleus. The translocated GV-$hATF6{\alpha}$ fragment strongly induced the expression of firefly luciferase in HeLa Luciferase Reporter cell line containing a stably integrated 5X GAL4 site-luciferase gene. The established double stable reporter cell line HLR-GV-$hATF6{\alpha}$(333) represents an innovative tool to investigate regulated intramembrane proteolysis of $ATF6{\alpha}$. It can substitute active pATF6(N) binding motif-based reporter cell lines.

• BMB Reports
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• v.52 no.11
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• pp.665-670
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• 2019

Nucleotide-binding oligomerization domain protein 2 (NOD2), an intracellular pattern recognition receptor, plays important roles in inflammation and cell death. Previously, we have shown that NOD2 is expressed in vascular smooth muscle cells (VSMCs) and that NOD2 deficiency promotes VSMC proliferation, migration, and neointimal formation after vascular injury. However, its role in endoplasmic reticulum (ER) stress-induced cell death in VSMCs remains unclear. Thus, the objective of this study was to evaluate ER stress-induced viability of mouse primary VSMCs. NOD2 deficiency increased ER stress-induced cell death and expression levels of apoptosis mediators (cleaved caspase-3, Bax, and Bak) in VSMCs in the presence of tunicamycin (TM), an ER stress inducer. In contrast, ER stress-induced cell death and expression levels of apoptosis mediators (cleaved caspase-3, Bax, and Bak) were decreased in NOD2-overexpressed VSMCs. We found that the $IRE-1{\alpha}-XBP1$ pathway, one of unfolded protein response branches, was decreased in NOD2-deficient VSMCs and reversed in NOD2-overexpressed VSMCs in the presence of TM. Furthermore, NOD2 deficiency reduced the expression of XBP1 target genes such as GRP78, PDI-1, and Herpud1, thus improving cell survival. Taken together, these data suggest that the induction of ER stress through NOD2 expression can protect against TM-induced cell death in VSMCs. These results may contribute to a new paradigm in vascular homeostasis.