• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.4
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• pp.929-935
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• 2008

As internet telephony services based on Session initiation Protocol (SIP) enter the spotlight as marketable technology, many products based on SIPs have been developed and utilized for home and office telephony services. The call connection of an internet phone is classified into specific call connections and group call connections. Group call connections have a forking function which delivers the message to all of the group members. This function requires excessive message control for a call connection and creates heavy traffic in the network. In the internet cail system model. most of the call-setup messages are directed to the proxy server during a short time period. This heavy message load brings an unwanted delay in message processing and. as a result, call setup can not be made. To solve the delay problem, we simplified the analysis of the call-setup message in the proxy server, and processed the forking function distributed for the group call-setup message. In this thesis, a new system model to minimize the load is proposed and the subsequent implementation of this model demonstrates the performance improvement.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.9
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• pp.2118-2135
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• 2012

With the rapid development of heterogeneous emerging wireless technologies and numerous types of mobile devices, the need to support robust mobile video streaming based on the seamless handover in Future Internet is growing. To support the seamless handover, several IP-based mobility management protocols such as Mobile IPv6 (MIPv6), fast handover for the MIPv6 (FMIPv6), Hierarchical MIPv6 (HMIPv6) and Proxy Mobile IPv6 (PMIPv6) were developed. However, MIPv6 depreciates the Quality-of-Service (QoS) and FMIPv6 is not robust for the video services in heterogeneous emerging wireless networks when the Mobile Node (MN) may move to another visited network in contrast with its anticipation. In Future Internet, the possibility of mobile video service failure is more increased because mobile users consisting of multiple wireless network interfaces (WNICs) can frequently change the access networks according to their mobility in heterogeneous wireless access networks such as 3Generation (3G), Wireless Fidelity (Wi-Fi), Worldwide Interoperability for Microwave Access (WiMax) and Bluetooth co-existed. And in this environment, seamless mobility is coupled according to user preferences, enabling mobile users to be "Always Best Connected" (ABC) so that Quality of Experience is optimised and maintained. Even though HMIPv6 and PMIPv6 are proposed for the location management, handover latency enhancement, they still have limit of local mobility region. In this paper, we propose a robust mobile video streaming in Heterogeneous Emerging Wireless Systems. In the proposed scheme, the MN selects the best-according to an appropriate metric-wireless technology for a robust video streaming service among all wireless technologies by reducing the handover latency and initiation time when handover may fail. Through performance evaluation, we show that our scheme provides more robust mechanism than other schemes.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.4
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• pp.1344-1367
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• 2014

Mobile traffic is increasing a masse because of the propagation of the Internet and the development of wireless mobile technology. Accordingly, the Network Local Mobility Management (NETLMM) working group [1] of the Internet Engineering Task Force (IETF) has standardized Proxy Mobile IPv6 (PMIPv6) [2] as a protocol for accomplishing the transmissibility of mobile terminals. PMIPv6 is a network-led IP-based mobility management protocol, which can control terminal mobility without depending on the type of access system or the capability of the terminal. By combining PMIPv6 and the mobility of Session Initiation Protocol (SIP), we can establish terminal mobility and session mobility through a more effective route. The mobility function can be improved and the overlap of function reduced as compared to that in the case of independent operation. PMIPv6 is appropriate for a non-real-time service using TCP, and SIP is appropriate for a real-time service using RTP/UDP. Thus, in the case of a terminal using both services, an effective mobility management is possible only by using PMIPv6 together with SIP. In order to manage mobility in this manner, researches on PMIPv6-SIP are in progress. In line with this trend, this paper suggests a new PMIPv6-SIP architecture where when a mobile terminal conducts a handover, a network-led handover while maintaining the session without the addition of a special function or middleware is possible along with effective performance evaluation through mathematical modeling by comparing the delay and the packet loss that occur during the handover to the Pure-SIP.

• Korean Journal of Veterinary Research
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• v.39 no.5
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• pp.878-895
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• 1999

Ischemic preconditioing (IPC), i.e., a preliminary brief episode of ischemia and reperfusion, has been shown to reduce the cell damage induced by long ischemia and reperfusion. Superoxide radical which is produced during reperfusion after ischemia was recognized as a factor of the ischemic injury and it is dismutated into $H_2O_2$ and $O_2$ by two types of intracellular superoxide dismutase (SOD), Cu,Zn-SOD in cytoplasm and Mn-SOD in mitochondria. Recently oxygen free radicals are suggested to induce the apoptosis, however mechanism of the reduced apoptosis by ischemic preconditioing was unknown, while many studies performed in mammalian heart indicated that ATP-sensitive $K^+$ ($K_{APT}$) channel activation related with the protective effects. The aim of present study is to investigate 1) whether IP upregulate the Cu,Zn-SOD and Mn-SOD activities, and 2) whether ischemic preconditioning decreases apoptosis via $K_{APT}$ channel activation in timely reperfused skeletal muscle after long ishemia. The experimental animals, Sprague-Dawley rats weighing 250~300g, were divided into 8 groups; 1) control group, 2) ischemic preconditioning only groups, 3) pinacidil, a $K_{APT}$ channel opener, treatment only groups, 4) glibenclamide, a $K_{APT}$ channel blocker, treatment only groups, 5) ischemia groups, 6) ischemia after IPC groups, 7) ischemia and pinacidil treatment groups, and 8) IP and ischemia after glibenclamide pretreatment groups. Animals of the control group were administered with the vehicle (DMSO) alone. Pinacidil (1mg/kg) was administered intravenously 5 minutes after initiation of ischemia, and glibenclamide (0.5mg/kg) was injected intravenously 20 minutes before IPC. In rats that were ischemic preconditioned, the left common iliac artery was occluded for 5 minutes followed by 5 minutes of reperfusion by three times using vascular clamp. Ischemia was done by occlusion of the same artery for 4 hours. The specimens of left rectus femoris muscle were obtained immediately (0 hour), 12 hours, 24 hours after drug administrations, IP or ischemia and reperfusion. The immunoreactivities of SOD and its alterations were observed by use of sheep antihuman Cu,Zn-SOD and Mn-SOD antibodies on the $10{\mu}m$ cryosections. The incidencies of apoptosis were observed by TUNEL methods with in situ apoptosis detection kit on $6{\mu}m$ paraffine section. The results obtained were as follows : 1. After IPC, immunoreactivities of Cu,Zn-SOD mainly in the small-sized fibers were increased by 24 hours, that of Mn-SOD at 0 hour and 24 hours. 2. No significant changes in immunoreactivities of SOD was observed in the pinacidil and in the glibenclamide treatment only groups, and in the ischemia only groups. 3. The immunoreactivities of the Cu,Zn-SOD were increased in the ischemia after IPC groups and the ischemia and pinacidil treatment groups. 4. The immunoreactivities of the Cu,Zn-SOD in the IPC and ischemia after glibenclamide pretreatment groups were not increased except for the 12 hours reperfusion group. But, Mn-SOD immunoreactivities were increased in the 0 hours, 12 hours and 24 hours after reperfusion. 5. In the control group, the IPC only groups, and the pinacidil treatment only groups, negative or trace apoptotic reactions were observed, but the positive apoptotic reaction occured in the glibenclamide treatment groups. 6. Moderate or many number of apoptosis were revealed in the ischemia groups, and also the IPC and ischemia after glibenclamide pretreatment group except for 12 hours and 24 hours after reperfusion. However, the incidence of apoptosis was decreased in the ischemia after IPC groups and in the ischemia and pinacidil treatment groups. 7. There is a coincidence between the increase of Cu,Zn-SOD immunoreactivities and the decrease of apoptosis in the presence of ischemia and reperfusion. These results suggest that the protective effects of ishemic preconditioing may related to the SOD activation, and the ischemic preconditioning decreases the apoptosis partially via $K_{APT}$ channel activation in timely reperfused rat skeletal muscle. It is also suggested that inhibition of apoptosis by IPC may related with the SOD activation.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2006.05a
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• pp.417-420
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• 2006

UPnP presents home network middleware for local home electrical appliances basedon internet protocols that is available access and control electrical appliances just in local home network. Itis designed to bring easy-to-use, flexible, standards-based connectivity to ad-hoc or unmanaged networks in the home, a small business, public spaces, or attached to the Internet. In this paper, Internet Gateway expands UPnP IGD(Internet Gateway Device) DCP(Device Control protocol) and UPnP IGP Bridge for Internet Home Network Electrical Appliance Control. UPnP IGD DCP is configurable initiation and sharing of internet connections, advanced connection-management features, management of host configuration service, and supports transparent Internet access by non-UPnP-certified devices. UPnP Bridge search for local home network devices by sending control messages. Control Point of UPnP Bridge search for devices of interest on the network and can control or be controlled all of functions by IGD DCP with control commands. Outside client, approach to UPnP IGD DCP, send control messages UPnP Bridge, and invoke each UPnP device. As a result, Electrical Appliance of Home Network base on UPnP, can control and be controlled via the Internet like ones in the one Home Network without modification of existing UPnP.

• Journal of Life Science
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• v.25 no.6
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• pp.703-708
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• 2015

Hox genes encode a highly conserved family of homeodomain-containing transcription factors controlling vertebrate pattern formation along the anteroposterior body axis during embryogenesis. Retinoic acid (RA) is a key morphogen in embryogenesis and a critical regulator of both adult and embryonic cellular activity. Specifically, RA regulates Hox gene expression in mouse- or human-derived embryonic carcinoma (EC) cells. Histone modification has been reported to play a pivotal role in the process of RA-induced gene expression and cell differentiation. As histone modification is thought to play an essential role in RA-induced Hox gene expression, we examined RA-induced initiation of collinear expression of Hox genes and the corresponding histone modifications in F9 murine embryonic teratocarcinoma (EC) cells. Hox expression patterns and histone modifications were analyzed by semiquantitative RT-PCR, RNA-sequencing, and chromatin immuno-precipitation (ChIP)-PCR analyses. The Hoxc4 gene (D0) was initiated earlier than the Hoxc5 to –c10 genes (D3) upon RA treatment (day 0 [D0], day 1 [D1], and day 3 [D3]). The Hox nonexpressing D0 sample had a strong repressive marker, H3K27me3, than the D1 and D3 samples. In the D1 and D3 samples, reduced enrichment of the H3K27me3 marker was observed in the whole cluster. The active H3K4me3 marker was closely associated with the collinear expression of Hoxc genes. Thus, the Hoxc4 gene (D1) and all Hoxc genes (D3) expressed H3K4me3 upon transcription activation. In conclusion, these data indicated that removing H3K27me3 and acquiring H3K4me3 regulated RA-induced Hoxc gene collinearity in F9 cells.