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Analysis of trends in patents on insect-derived medicinal materials for skin diseases (곤충 유래 한약재를 활용한 피부질환 개선 기능성 소재에 대한 특허 동향 분석)

  • Lee, Ji Hye;Moon, Byeong Cheol;Nam, Hyeon Hwa;Kim, Joong Sun
    • The Korea Journal of Herbology
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    • v.35 no.2
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    • pp.39-46
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    • 2020
  • Objective: In this study, we analyzed the trend of patents registered prior to October 4, 2019, to understand the industrial trends in insect-derived medicinal materials used for the treatment of skin diseases. Methods: Using the WIPSON database, we collected information regarding the patents related to insect-derived materials for treating various skin diseases. Results: The patents registered prior to October 4, 2019, from Korea, Japan, the USA, China, and the EU, along with those registered under PCT were selected. There were 195 patents related to the use of insect-derived medicinal materials in treating various skin diseases such as psoriasis, inflammatory skin diseases, eczema, pruritus, and atopic dermatitis. China is mostly superior in total number of registered patents compared with the other countries. Korea was the major patent technology-holder for atopic dermatitis, but China dominated in the remaining categories of skin diseases. Upon first patent registration in 1992, there had been a continual increase in the number of patents. Especially, patents related to eczema, psoriasis, inflammatory skin disease were markedly increased. Most frequently used insect-derived medicinal materials was Scolopendra, Cicadidae Periostracum, Scorpions, Cantharides, and Batryticatus Bombyx. The insect-derived medicinal materials were generally used as a combined preparation with other medicinal materials in patents. Conclusion: This study could help to establish the basis for future research and development related treating skin diseases using insect-derived medicinal materials. In order to provide sufficient data, further study including analysis of rejected patents is needed.

Study on the Effects of the Healing Programs Using Emotional Insects - Bombyx mori (Linnaeus) Case - (정서곤충을 이용한 치유프로그램의 효과 분석 - 누에나방 사례 -)

  • Kim, So-Yun;Ji, Sangmin;Kim, Wontae;Song, Jeong-Hun
    • Korean journal of applied entomology
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    • v.61 no.2
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    • pp.283-288
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    • 2022
  • The study aimed to investigate the psychological effect of the emotional insect-assisted healing program on the stress experienced by 43 children in a community child center. Silkworm (Bombyx mori [Linnaeus]) was used in the healing programs, and the stress was measured using salivary alpha-amylase levels. Saliva samples and a survey on insect preference were collected before and after the healing programs, respectively. After the program, the satisfaction score for participation was evaluated. Results indicate that the emotional insect-assisted healing programs led to statistically significant lowering of salivary alpha-amylase levels and increased the preference for insects. The children's satisfaction in the healing program activities using silkworms was 4.23 points out of 5.

An efficient production management of the silkworm variety "Daewhangjam" through low temperature in a pupa

  • Chan Young Jeong;Sang Kug Kang;Seong-Wan Kim;Hyun-Bok Kim;Jong Woo Park;Ji Hae Lee;Kee-Young Kim;Seong Ryul Kim
    • International Journal of Industrial Entomology and Biomaterials
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    • v.47 no.1
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    • pp.44-50
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    • 2023
  • The Daehwangjam has excellent marketability and quality. However, precise silkworm breeding data on the recent high-temperature environment is not enough collected, and it is necessary to check whether stable Daewhangjam silkworm egg production was possible in poor environments. In this study, the timing of metamorphosis of the Daewhangjam parents Jam323 and Jam324 silkworms, in an optimal condition and a general condition similar to breeding grounds, was investigated to confirm that appropriate mating was achieved. Surprisingly, a number of female moths were discarded due to the metamorphosis of Jam324 female moths much earlier than Jam323 male moths in either an optimal or a general condition. To improve this, during the Jam324 female pupation period, the mild low-temperature of 15℃ was treated for the pupation period to delay the metamorphosis into female moths. Depending on the treatment period, the metamorphosis of the female pupa was delayed by more than 4 days, allowing normal mating with the Jam323 male moth. The eye pigments in a pupa also slowly accumulated in these treatments. In order to discover the side effects of low-temperature treatments, the voltinism of the Daewhangjam eggs was investigated, but most of them remained univoltine. Taken together, the low-temperature treatment during the female pupation period made it possible to use Jam324 female moths that were should be discarded, which means that stable and efficient management of Daewhangjam egg production is possible.