• Title/Summary/Keyword: IL-22

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Health Zone_4050 멋지게 - 가슴 답답한데 소화기내과로 가는 이유는? 역류성 식도염

  • Min, Yeong-Il
    • 건강소식
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    • v.36 no.5
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    • pp.20-22
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    • 2012
  • 중소기업에 다니는 40대 중반의 남성은 얼마 전부터 종종 가슴이 화끈거리는 불쾌한 통증과 함께, 목과 가슴 사이에 복숭아씨가 걸려있는 듯한 답답함을 느꼈다. 혹시나 심장에 이상이 있는 것이 아닌지 검사를 해보았지만, 결과는 정상이었다. 이리저리 알아보다 위액이 역류하는 경우에도 비슷한 증상이 있을 수 있다는 정보를 얻고 소화기내과를 찾았고, 내시경 검사 결과 역류성 식도염 진단을 받았다.

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The Experimental Study on the Suppression Effect of Asthma and Immune Response Improvement of Platycodi Radix Herbal-acupuncture (길경약침(桔梗藥鍼)의 천식억제(喘息抑制) 및 면역조절효과(免疫調節效果)에 대(對)한 실험적(實驗的) 연구(硏究))

  • Park, Chi-Young;Kim, Young-Il;Hong, Kwon-Eui
    • Journal of Acupuncture Research
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    • v.22 no.6
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    • pp.61-74
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    • 2005
  • Objectives : The aim of this study was to investigate the effect of Asthma-depression and Immunoregulation with PR-HAS(Herbal-acupuncture with Platycodi Radix infusion solution) injection at Joksamni(St36) on ovalbumin-induced asthma in mice. Methods : C57BL/6 mice were sensitized and challenged with OVA(ovalbumin) for 12 weeks(once a week). The experimental group(OVA-PR-HA) wase treated with concentrations(1%) of PR-HAS at Joksamni(St36) for the later 8 weeks(3times/week). The second experimental group(OVA-Needle prick) was treated with Needle-Prick at Joksamni(St36) for the later 8 weeks(3times/week). Results : 1. The weight and total cells in the mice lung treated with PR-HA decreased significantly compared with that of control group. 2. Total leukocytes and eosinophils in BALF of the mice group treated with PR-HA decreased remarkably compared with those of control group. 3. The sticking of collagen on histological analysis of lung sections, the mice group treated with PR-HA decreased significantly compared with those of control group. 4. The concentrations of IL-4, IL-5, IgE in BALF, and IL-4, IL-5, IL-13 in serum of the mice group treated with PR-HA decreased significantly compared with those of control group. 5. The number of $Gr-1^+/CD11b^+\;and\;CD11b^+$ cells in the lungs of the mice group treated with PR-HA decreased significantly compared with that of control group. 6. The numbers of $CCR3^+\;cells,\;CD4^+\;cells\;and\;CD8^+\;cells$ in the lungs, and $CD3e^+/CD69^+$ in the lungs of the mice group treated with PR-HA decreased significantly compared with those of control group. 7. The mRNA expression of ${\beta}-actin,\;TNF-{\alpha}$, IL-4, IL-5,IL-13 in the mice group treated with PR-HA with RT-PCR decreased significantly compared with those of control group. Conclusion : The concentrations of IL-4, IL-5, IgE in BALF, and IL-4, IL-5, IL-13 in serum of the mice group treated with PR-HA decreased significantly compared with those of control group. The number of $Gr-1^+/CD11b^+\;and\;CD11b^+$ cells in the lungs of the mice group treated with PR-HA decreased significantly compared with that of control group. The numbers of $CCR3^+\;cells,\;CD4^+\;cells\;and\;CD8^+\;cells$ in the lungs, and $CD3e^+/CD69^+$ in the lungs of the mice group treated with PR-HA decreased significantly compared with those of control group. The mRNA expression of ${\beta}-actin,\;TNF-{\alpha}$, IL-4, IL-5, IL-13 in the mice group treated with PR-HA with RT-PCR decreased significantly compared with those of control group. These result suggests that Platycodi Radix Herbal-acupuncture at Joksamni(St36) in C57BL/6mice may be an effictive part to OVA-induced asthma in C57BL/6 mice.

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The Study on Application of Flying Inspection Method for the 22.9kV Distribution Line (22.9kV 배전선로 비행점검 방법 적용에 관한 연구)

  • Zhang, Jeong-Il;Kang, Byoung-Seok
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.61 no.2
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    • pp.194-198
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    • 2012
  • This paper describes flying inspection apparatus for 22.9kV distribution line. This apparatus is composed of multi-copter(more than 4 propellers), camcorder and remote controller. The existing inspections, such as hot-line inspection job and optical inspection method and distribution Line Checking Robot, have many restrictions. A electric working vehicle and hot-line job license are essential in hot-line inspection job. Besides its high cost, it can't be applied to the electric pole over 18m and road-blocked area. Optical method can't inspect upper side of electric facilities mounted on the electric pole. Robot method can't be applied to the corroded overhead earth wire and nothing of overhead earth wire. To solve the problems, in Korea Electric Power Co., we have applied flying inspection apparatus to the 22.9kV distribution line. The results of trial application show that this paper is practical and effective for the inspection technical method in 22.9kV distribution line

Effect of 0.5 mM Dibutyryl cAMP on Meiotic Maturation during Different Incubation Time and Embryonic Development Following In Vitro Fertilization or Parthenogenetic Activation in Porcine Oocytes

  • Yu, Il-Jeoung
    • Journal of Embryo Transfer
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    • v.26 no.4
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    • pp.251-256
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    • 2011
  • Presently, the effect of 0.5 mM dibutyryl cAMP (dbcAMP)-supplemented maturation medium during different incubation time on meiotic arrest (germinal vesicle) and resumption (metaphase II) of porcine oocytes and embryonic development of porcine oocytes following in vitro fertilization (IVF) or parthenogenetic activation (PA) was determined. Porcine cumulus oocyte complexes (COCs) were cultured in 0.5 mM dbcAMP for 17, 22, 27, or 42 h, and an additional 22 h without 0.5 mM dbcAMP. The nuclear status was examined at each time point. Oocytes cultured from 39~49 h displayed more than 80% meiotic resumption. More than 85 % of meiotic arrest was presented at 17~22 h. Oocytes were cultured for 22 h with 0.5 mM dbcAMP and additional 22 h without dbcAMP to assess developmental potential following IVF or PA. There were no significant differences in blastocyst rates among the dbcAMPIVF, IVF, dbcAMP-PA, and PA groups, although cleavage rate of IVF group was significantly higher than those of dbcAMP-PA, and PA groups. In conclusion, 0.5 mM dbcAMP influenced meiotic maturation of porcine oocytes depending on incubation time of oocyte, although embryonic development was not improved in both IVF and PA.