• 대한전기학회:학술대회논문집
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• 대한전기학회 2008년도 학술대회 논문집 정보 및 제어부문
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• pp.157-158
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• 2008

보완대제의학의 한분야인 Color Therapy에 대한 과학적 진단을 위해, 색(color)이 인체에 미치는 영향을 정량화 하기위한 선행 기초연구로서 자연광에 포함된 가시광선의 파장이 인체에 미치는 영향을 계측하고 분석하기 위한 시스템의 설계에 대하여 연구하였다. 인체를 구성하는 세포는 세포하나하나가 살아있는 생명체로서 주변환경에 대하여 반응을 하고, 그 반응으로부터 생체신호가 발생하며, 발생된 생계신호는 인체의 다양한 구성기관에 전달되고, 전달받은 기관은 그 신호에 반응한다[4][5]. 따라서 가시광선 영역의 색이 인체에 미치는 영 향분석은 보완대체의학 발전에 중요한 요소라 할 수 있다. 본 연구를 통해 설계한 "Color therapy 진단 System"은 가시광선 중에서 특정 파장대의 빛을 발생시켜 방사하며, 방사된 빛을 조사받은 사람의 신체가 반응하는 신체 상태를 한방적인 진단요소인 "맥", "기혈전류변화"[1][2], "체온변화"등을 계측하고 이를 정량화하는 연구를 수행하였다. 본 연구의 결과는 그 동안 시회저변에서 이루어지고 있던 보완대체의학 분야의 의료행위에 대한 과학화, 정량화를 위해 필요한 중요한 시발점으로 사료된다.

• 대한정형도수물리치료학회지
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• 제16권2호
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• pp.93-97
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• 2010

Purpose: The first purpose of this study was to determine the effect of reciprocal inhibition that influence changes in pain when applied to patients with culf cramps. The second purpose of this study was to determine the effect of manual therapy on iliaosacral joint that influence changes number of occurrences when applied to patients with frequent nocturnal culf cramps. Methods: The first study using reciprocal inhibition techniques to 20 patients with calf cramps and saw the change in pain. The second study using manual therapy on iliaosacral joint to 2 patients with frequent nocturnal culf cramps and saw the change in number of occurrences during the week. Results: The pain and number of occurrences were significantly difference between pre-treatment and post treatment. Conclusion: Based on the results of this study, we found that reciprocal inhibition decreased pain and that manual therapy on iliaosacral joint decreased number of occurrences.

• 혜화의학회지
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• 제16권2호
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• pp.1-5
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• 2007

Objectives : To exam the effect of Jungsongouhyul Herbal Acupuncture(JHA) Therapy for neck pain patients. Methods : We divided subjects into two groups : One is treated JHA theraphy after treated general acupuncture therapy. The other group is treated normal saline injection after treated same general acupuncture therapy. Results : The following result were obtained: 1. Age of average of general acupuncture therapy+JHA theraphy group is $37.30{\pm}4.38$ years and general acupuncture therapy+normal saline injection group is $36.25{\pm}4.09$ years. 2. VAS of change between two groups was significantly decreased(p<0.05). Conclusion : It is suggested that Jungsongouhyul Herbal Acupuncture Therapy has development-effectiveness on neck pain patients.

• 대한한의학회지
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• 제30권3호
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• pp.70-78
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• 2009

Objectives : This study was aimed at examining the effects of the application of EA (electroacupuncture) at GV20 and LI4 in the early cerebral ischemia on the size of cerebral infarction, COX-2 and IL-6. Methods : For this experiment, 21, six-week-old male S-D (Sprague - Dawley) rats weighting 160g to 200g were selected and randomly classified into 3 groups, seven rats in each group. Brain ischemia was simulated using a modified Koizumi method which was performed on each rat. In the GV20 group, the GV20 of the SD rats was stimulated for thirty minutes with acupunctural electrode low frequency stimulator five hours after inducement of ischemia. For the LI4 group, the LI4 was stimulated as above, while for the Ischemia group, no stimulation was applied. Twenty-four hours after the experiment, stained cerebral tissues were examined and an immuno-histological test was done to examine inflammatory reaction Results : Out of the three groups, the LI4 group showed the smallest size of cerebral infarction and the Ischemia group showed the highest COX-2 (cyclooxygenase-2) expression value in the cortex of the cerebrum. In addition, the LI4 group showed the lowest COX-2 expression value in unknown putamen out of the three groups. Conclusions : We infer that EA, applied at LI4 and GV20 in early ischemia, is effective in delaying the expression of IL-6 (interleukin-6) and COX-2, the inflammatory agents manifested from stroke. In addition, application at LI4, rather than GV20, can lower the expression value of the inflammatory agents. Further, EA can be an effective way to block early inflammatory reaction in stroke.

• 대한약침학회지
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• 제7권2호
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• pp.75-81
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• 2004

Objective : The purpose of this study is to report the efficiency of Bee Venom Therapy by managering of radial nerve palsy patients. Method : Three patients were treatmented by Bee Venom therapy and acupucture therapy. And we took pictures of someone's wrist and checked the power of muscles by the improving phase. Results : Almost cases shows the improvement in the movement of wrist and the numbness of hand. By using acuputure and Bee Venom therapy, the symptoms of radial nerv palsy was more fastly recovered.

• IMMUNE NETWORK
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• 제24권1호
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• pp.2.1-2.24
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• 2024

Studies over the last 2 decades have identified IL-17 and IL-21 as key cytokines in the modulation of a wide range of immune responses. IL-17 serves as a critical defender against bacterial and fungal pathogens, while maintaining symbiotic relationships with commensal microbiota. However, alterations in its levels can lead to chronic inflammation and autoimmunity. IL-21, on the other hand, bridges the adaptive and innate immune responses, and its imbalance is implicated in autoimmune diseases and cancer, highlighting its important role in both health and disease. Delving into the intricacies of these cytokines not only opens new avenues for understanding the immune system, but also promises innovative advances in the development of therapeutic strategies for numerous diseases. In this review, we will discuss an updated view of the immunobiology and therapeutic potential of IL-17 and IL-21.

• The Journal of Korean Physical Therapy
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• 제10권1호
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• pp.253-263
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• 1998

To provide physical therapy service of good quality keeping people healthy and obstain structural reformation coping with the demands of in medical service market to foreign intercourse on 21C, we should make legal system fer the physical therapy practice. Thus we suggest the Ministry of Health and Health and the authorities should, 1. Exclude the provision of physical therapist from the classfication of medical technician on the Medical Technician Law Article 2. and establish the independent Physical Therapist Law 2. Eliminate the provision of physician or dentist's guide the Medical Technician Law Article 1. or reform it to physician or dentist's request so that physical therapists may have a independent practice, or 3. Add the provision of the physical therapy center to the Medical Technician Law, the enforcement ordinances and enforcement regulations, such as the provision of optometrist or dental technician.

• 대한의생명과학회지
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• 제24권3호
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• pp.157-167
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• 2018

The concept of gene therapy is to treat a disease by transferring therapeutic nucleic acids to a patient's cells. It took several decades from the basic theoretical proposal of gene therapy to the current promising treatment option for some important human diseases. The encountered adverse effects in the early clinical studies boosted the development of sophisticated vectors and elaborate clinical designs. The gene therapy is now considered to have the potential to cure many diseases that are incurable with conventional medications. By the end of 2017, about 2,600 clinical trials of gene therapy have been performed or are ongoing for a variety of diseases such as cancers, monogenic diseases, cardiovascular diseases and neurological diseases etc. Here, we present a brief introduction of technical achievement in relation to gene therapy development, and a review of the current status of global gene therapy clinical development.

• 한국전문물리치료학회지
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• 제27권3호
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• pp.199-205
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• 2020

Background: The classification of foot type can be commonly determined by the height of the media longitudinal arch. The normalized arch height (NAH) is defined as the ratio of navicular or instep heights to the foot length or instep length. Objects: This study investigated the relationships among foot characteristics, such as foot length (FL), instep length (IL), navicular height (NH), and instep height (IH), in Korean young adults. Also, the distribution of foot type based on calculated NAH was assessed. Methods: Three-dimensional foot scanning data of young adults aged 20 to 39 years (total: 1,978; 974 male, 1,004 female) were obtained from the Korea Technology Standards Institute, and used for analyses. NAH was calculated as the following: NH/FL, IH/FL, IH/IL, NH/IL. Spearman's rank order correlation was used to identify correlations among variables. The Mann-Whitney U-test and chi-square test were used to compare the sex differences in foot characteristics and distribution of foot type. Results: FL and IL showed a very high correlation (r = 0.94). The correlations between FL or IL and IH (r = 0.50-0.57) were greater than those between FL or IL and NH (r = 0.23-0.72). Males had significantly larger values than females (p < 0.001), and the frequency of pes planus was significantly higher in females than in males (χ² = 50.09, p < 0.001). Based on the IH/IL index, the neutral foot, pes planus and pes cavus distributed by 16%, 78%, and 6% respectively. Conclusion: Our results on foot arch distribution could be used as basic data in clinical or footwear fields, and our data on differences in arch structure according to sex may facilitate understanding of why injury to the lower limbs differs between males and females.

• Journal of Microbiology and Biotechnology
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• 제23권4호
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• pp.518-526
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• 2013

Gut-derived lipopolysaccharides (LPS) are critical to the development and progression of chronic low-grade inflammation and metabolic diseases. In this study, the effects of probiotics Lactobacillus and Bifidobacterium on gut-derived lipopolysaccharide and inflammatory cytokine concentrations were evaluated using a human colonic microbiota model. Lactobacillus reuteri, L. rhamnosus, L. plantarum, Bifidobacterium animalis, B. bifidum, B. longum, and B. longum subsp. infantis were identified from the literature for their anti-inflammatory potential. Each bacterial culture was administered daily to a human colonic microbiota model during 14 days. Colonic lipopolysaccharides, and Gram-positive and negative bacteria were quantified. RAW 264.7 macrophage cells were stimulated with supernatant from the human colonic microbiota model. Concentrations of TNF-${\alpha}$, IL-$1{\beta}$, and IL-4 cytokines were measured. Lipopolysaccharide concentrations were significantly reduced with the administration of B. bifidum ($-46.45{\pm}5.65%$), L. rhamnosus ($-30.40{\pm}5.08%$), B. longum ($-42.50{\pm}1.28%$), and B. longum subsp. infantis ($-68.85{\pm}5.32%$) (p < 0.05). Cell counts of Gram-negative and positive bacteria were distinctly affected by the probiotic administered. There was a probiotic strain-specific effect on immunomodulatory responses of RAW 264.7 macrophage cells. B. longum subsp. infantis demonstrated higher capacities to reduce TNF-${\alpha}$ concentrations ($-69.41{\pm}2.78%$; p < 0.05) and to increase IL-4 concentrations ($+16.50{\pm}0.59%$; p < 0.05). Colonic lipopolysaccharides were significantly correlated with TNF-${\alpha}$ and IL-$1{\beta}$ concentrations (p < 0.05). These findings suggest that specific probiotic bacteria, such as B. longum subsp. infantis, might decrease colonic lipopolysaccharide concentrations, which might reduce the proinflammatory tone. This study has noteworthy applications in the field of biotherapeutics for the prevention and/or treatment of inflammatory and metabolic diseases.