• Title/Summary/Keyword: IIA

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Laryngeal Electromyography

  • Lee, In-Ja
    • Proceedings of the KSLP Conference
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    • 1994.06a
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    • pp.138-142
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    • 1994
  • Types of muscle fiber (Table omitted) Thyroarytenoid ; higher proportion of TypeII fiber. Post.cricoarytenoid. Higher proportion of Type fiber ; 52-67%. Type II fiber ; IIA dominant. Rapid contraction &fatigue ressitant ; appropriate for endurant action of respiration. Muscle fiber type grouping(Teig E et al, 1978). (omitted)

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Synthesis of Nucleophilic Adducts of thiols (VIII). Addition of Thioglycolic acid, Benzenethiol and Benzylmercaptan to ${\beta}$-Acetyl-${\beta}$-benzoylstyrene Derivatives (Thiol의 친핵성 첨가물의 합성 (제VIII보) ${\beta}$-Acetyl-${\beta}$-benzoylstyrene 유도체에 대한 thioglycolic acid, benzenethiol 및 benzylmercaptan 첨가 생성물의 합성)

  • Tae-Sung Huh;In-Sook Baek;Kih-Rim Seo;Tae-Rim Kim
    • Journal of the Korean Chemical Society
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    • v.31 no.4
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    • pp.364-368
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    • 1987
  • The addition reactions of thioglycolic acid, benzenethiol and benzylmercaptan to ${\beta}-acetyl-{\beta}-benzoylstyrene$ were investigated. ${\beta}-Acetyl-{\beta}-benzoylstyrene$ derivatives easily underwent addition reactions with thioglycolic acid, benzenethiol, and benzylmercaptan to form five(2-acetyl-2-benzoyl-1-phenylethyl) thioglycolic acid derivatives (IIa-IIe), five (2-acetyl-2-benzoyl-1-phenylethyl)benzenethiol (IIIa-IIIe) derivatives and five (2-acetyl-2-benzoyl-1-phenylethyl)benzylmercaptan derivatives (IVa-IVe), respectively.

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Ovarian Metastasis and other Ovarian Neoplasms in Women with Cervical Cancer Stage IA-IIA

  • Ngamcherttakul, Vijit;Ruengkhachorn, Irene
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.9
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    • pp.4525-4529
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    • 2012
  • Objectives: To determine the prevalence and predicting factors of ovarian metastasis, and evaluate the histology of other ovarian neoplasms in women with early-stage cervical cancer. Methods: The medical records of women with cervical cancer stage IA-IIA who underwent primary surgical treatment at Siriraj Hospital, Mahidol University from January 2007 to December 2011 were used for the study. Demographic, clinical and histopathologic data of the women who underwent salpingo-oophorectomy were reviewed. Results: Of 264 women, the mean age was 52.3 years. The types of hysterectomy procedures were composed of 210 radical hysterectomy, 9 modified radical hysterectomy, 40 simple hysterectomy, and 5 abandoned hysterectomy. The prevalence of ovarian metastasis was 0.76% (2/264). All of ovarian metastatic patients were older than 60 years old, postmenopause, and had macroscopical stage IB1 cervical cancer. Others ovarian tumors were found in 7 patients including 1 synchronous ovarian carcinoma, 1 serous cystadenoma, 1 fibroma, and 4 teratoma. Conclusions: In cases of early-stage cervical carcinoma of the population studied, ovarian preservation could be another option in <60-year-old patients, with non-neuroendocrine cell type, stage IA, and no extracervical or ovarian lesions.

Overview of muscle metabolism, muscle fiber characteristics, and meat quality

  • Choe, Jeehwan
    • Korean Journal of Agricultural Science
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    • v.45 no.1
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    • pp.50-57
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    • 2018
  • Meat comes from the skeletal muscles of farm animals, such as pigs, chickens, and cows. Skeletal muscles are composed of many muscle fibers. Muscle fibers are categorized into three types, fiber type I, IIA, and IIB, based on their contractile speed and metabolic properties. Different muscle fiber types have different biochemical, physiological, and biophysical characteristics. Especially, the characteristics of muscle fiber type I and IIB are opposite to each other. Muscle fiber type I has a relatively strong oxidative metabolic trait and a higher content of lipids. In contrast to fiber type I, muscle fiber type IIB has a strong glycolytic metabolic trait and a relatively lower content of lipids and a higher content of glycogen. Muscle fiber type IIA has intermediate properties between fiber type I and IIB. Thus, muscles with different fiber type compositions exhibit different ante- and post-mortem muscle characteristics. In particular, the different metabolic traits of muscles due to the different compositions of the fiber types strongly affect the biochemical and physiological processes during the conversion of muscle to meat and subsequently influence the quality of the meat. Therefore, understating muscle metabolism and muscle fiber characteristics is very important when discussing the traits of meat quality. This review is an overview on basic muscle metabolism, muscle fiber characteristics, and their influence on meat quality and finally provides a comprehensive understanding about the fundamental traits of muscles and meat quality.

A Histochemical Study of the Masseter Muscle Fibers of White Rat with Unilateral Edentulous Jaw (편측 무치악이 백서 교근 근섭유에 미치는 영향에 관한 조직화학적 연구)

  • Hong-Ryeol Ryu;Sung-Woo Lee
    • Journal of Oral Medicine and Pain
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    • v.13 no.1
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    • pp.61-69
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    • 1988
  • The study of the muscle fiver composition and the muscle fiver type conversion during unilateral edentulous condition was undertaken in the rostral superficial masseter muscle of the whiter rat. 16 4-week-old male white rats weighting approximately 130gm that crowns of left upper and lower molare were cut intentionally, were divided into 4 groups (one control group and 3 experimental groups). After experimental groups were sacrificed by etherization in 6 days($E_1$), 18 days($E_2$) and 36 days($E_3$) separately, samples of the rostral superficial masseter muscle were obtained bilaterally and the proportion of type I, type IIA, type IIB, and type IIC fibers was determined and counted according to their histochemical activity of myosin ATPase (at pH 9.4, pH 4.6, and pH 4.2)and PAD staining. The obtained results were as follows : 1. The rostral superficial masseter muscle of the white rat contained approximately 47.5% type I fiber and 52.5% type II fiber. 2. Type I/ Type II ratio of molar-present side was increased significantly in the group E2 (18 days group) 3. Type IIA fiber was increased at molar-present side and decreased at molar-absent side in experimental groups.

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Role of histone deacetylase 2 and its posttranslational modifications in cardiac hypertrophy

  • Eom, Gwang Hyeon;Kook, Hyun
    • BMB Reports
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    • v.48 no.3
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    • pp.131-138
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    • 2015
  • Cardiac hypertrophy is a form of global remodeling, although the initial step seems to be an adaptation to increased hemodynamic demands. The characteristics of cardiac hypertrophy include the functional reactivation of the arrested fetal gene program, where histone deacetylases (HDACs) are closely linked in the development of the process. To date, mammalian HDACs are divided into four classes: I, II, III, and IV. By structural similarities, class II HDACs are then subdivided into IIa and IIb. Among class I and II HDACs, HDAC2, 4, 5, and 9 have been reported to be involved in hypertrophic responses; HDAC4, 5, and 9 are negative regulators, whereas HDAC2 is a pro-hypertrophic mediator. The molecular function and regulation of class IIa HDACs depend largely on the phosphorylation-mediated cytosolic redistribution, whereas those of HDAC2 take place primarily in the nucleus. In response to stresses, posttranslational modification (PTM) processes, dynamic modifications after the translation of proteins, are involved in the regulation of the activities of those hypertrophy-related HDACs. In this article, we briefly review 1) the activation of HDAC2 in the development of cardiac hypertrophy and 2) the PTM of HDAC2 and its implications in the regulation of HDAC2 activity.

A Clinical Study of Valve Repair of the Mitral Valvular Disease (승모판막 질환의 판막 재건술에 대한 임상연구)

  • 김민호
    • Journal of Chest Surgery
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    • v.27 no.9
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    • pp.752-758
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    • 1994
  • From July 1983 to December 1992, 145 patients with mitral valvular disease underwent open heart surgery at Chonbuk National University Hospital. Of these patients, 89 patients[61.4%] required mitral valve replacement. 56 patients [38.6 %] had mitral valve repair. There were 32 women and 24 men and the mean age was 34.3 years[range 6 years to 62 years].There were 23 cases of pure mitral stenosis, 19 cases of mitral regurgitation and 14 cases of mixedmitral valvular disease. The mean duration of symptom was 4.53 years and mean mitral valvularorifice diameter[in cases of pure stenosis and mixed mitral valvular lesion] was 0.96 cm. According to the NYHA classification, the distribution of patients preoperatively was as follows; class IIa, 15 patients; class lib, 17 patients; class III, 22 patients; class IV, 2 patients. Four patients[7%] had an embolic history preoperatively. 24 patients[ 43 %] were in atrial fibrillation. In cases of pure mitral stenosis, the technique used included open mitral commissurotomy[21atients], open mitral commissurotomy with mitral annuloplasty[2 patients]. In mixed mitral valvular disease, open mitral commissurotomy[ll patients] and open mitral commissurotomy with mitral annuloplasty[l patient] were performed. In cases of mitral regurgitation, mitral annuloplasty[5 patients], mitral valvuloplasty[6 patients], mitral annuloplasty with valvuloplasty [3 patients] and ring annuloplasty [5 patients] were performed.There was one perioperative death related to acute renal failure and sepsis. One late death was occurred related to heart failure after 10 months postoperatively. One patient required reoperation due to restenosis and no embolic episode was occured. After operation, 34 patients were in NYHA functional class I, 20 patients were in class IIa.

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Conjoint-like Analysis Using Elimination-by-Aspects Model (EBA 모형을 활용한 유사 컨조인트 분석)

  • Park, Sang-Jun
    • Korean Management Science Review
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    • v.25 no.1
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    • pp.139-147
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    • 2008
  • Conjoint Analysis is marketers' favorite methodology for finding out how buyers make trade-offs among competing products and suppliers. Thousands of applications of conjoint analysis have been carried out over the past three decades. The conjoint analysis has been so popular as a management decision tool due to the availability of a choice simulator. A conjoint simulator enables managers to perform 'what if' question accompanying the output of a conjoint study. Traditionally the First Choice Model (FCM) has been widely used as a choice simulator. The FCM is simple to do, easy to understand. In the FCM, the probability of an alternative is zero until its value is greater than others in the set. Once its value exceeds that threshold, however, it receives 100%. The LOGIT simulation model, which is also called as "Share of Preference", has been used commonly as an alternative of the FCM. In the model part worth utilities aren't required to be positive. Besides, it doesn't require part worth utilities computed under LOGIT model. The simulator can be used based on regression, monotone regression, linear programming, and so on. However, it is not free from the Independent from Irrelevant Alternatives (IIA) problem. This paper proposes the EBA (Elimination-By-Aspects) model as a useful conjoint-like method. One advantage of the EBA model is that it models choice in terms of the actual psychological processes that might be taking place. According to EBA, when choosing from choice objects, a person chooses one of the aspects that are effective for the objects and eliminates all objects which do not have this aspect. This process continues until only one alternative remains.