• The Transactions of The Korean Institute of Electrical Engineers
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• v.59 no.8
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• pp.1497-1505
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• 2010

The present study was performed to investigate the effect of aging on muscular activity of older subjects under the condition of fixed load muscle contraction. SEMG signals were recorded from old (46 women) and young (45 women) groups performing sustained isometric elbow flexion contraction with a fixed load during 30 seconds. Linear regression and mean square error (MSE) analysis with four characteristic variables (ARV, RMS, MDF, MNF) were used to compare the age-related difference (of local muscle fatigue and fluctuation of the amplitude and frequency) in the SEMG signal. The main results can be summarized as follows: During sustained muscle contraction with a fixed load: i) the MSE values of amplitude (ARV, RMS) and frequency (MDF, MNF) variables were more than 30% higher for the young than for the old adults; ii) the measures of local muscle fatigue (slope of the MDF and MNF) indicated greater fatigue in the old; and iii) the rate of increase of the SEMG amplitude was higher for the young than the old.

• Asian-Australasian Journal of Animal Sciences
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• v.7 no.3
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• pp.405-411
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• 1994

Purified myofibrils were prepared from ante-mortem stress and control lots of Taiwan country chicken breast and thigh muscles at death and afler storage at $4^{\circ}C$ for 0, 1, 2, 3, and 7 days post-mortem. Sodium dodecyl sulfate polycrylamide gel electrophoresis (3.2%) and densitometer were used to examine the effect of ante-mortem stress and control storage of muscle on titin and nebulin. Results indicated that titin and nebulin were more rapidly degraded in the control and the ante-mortem stress light muscles than in the control and ante-mortem dark muscles of Taiwan country chicken. In contrast, nebulin was shown to be more resistance to degradation in the ante-mortem stress dark muscle than in the control light muscle.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.2
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• pp.11-17
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• 2019

Purpose : The purpose of this study was to determine the effects of specific frequency and application timing of microcurrent (MC) on the mechanical property of muscle caused by delayed onset muscle soreness (DOMS). Methods : The subjects were 32 healthy adults with 8 subjects randomly assigned to four groups (I; 40 Hz MC while inducing DOMS, II; 40 Hz MC immediately after inducing DOMS, III; 284 Hz MC while inducing DOMS, IV; 284 Hz MC immediately after inducing DOMS). DOMS is applied to the biceps brachii muscle while MC was applied at an intensity of $300{\mu}A$ for 10 minutes. The mechanical properties of muscle were measured before and immediately after DOMS. Results : In terms of muscle tone, there were significant differences in interaction effects between time and groups. Regarding muscle elasticity and stiffness, there were no significant differences in interaction effects between time and groups but there were only significant differences in main effects based on time. Conclusion : The results indicated that 40 Hz MC had an effect on reducing muscle tone regardless of application timing. However, both 40 Hz and 284 Hz MC did not trigger changes in muscle elasticity and stiffness regardless of application timing.

• Journal of Haehwa Medicine
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• v.24 no.2
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• pp.17-24
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• 2016

Objectives : This study was aimed to widen range of comprehesion about meridian muscle system through myological study of meridian muscle system and comparison with deep front arm line in anatomical train Methods : We have studied the similarity and difference between Hand Great Yin Lung Meridian Muscle System and Deep Front Line in Anatomical Train through Principles of Meridians & Acupoints, publications about myology, Anatomical trains. Results : I. Like another advanced studies, muscular system of hand great yin showed similarity to deep front line in anatomical train. II. It is considered that muscular system of hand great yin contains Musculus abductor pollicis brevis, Musculus extensor hallucis longus, Musculus brachioradialis, Musculus biceps brachii, Musculus subclavius, Musculus pectoralis major. III. Comparing muscular system of hand great yin to deep front arm line in anatomical train it showed similarity to part of muscles and pathological symptoms. But it showed difference to part of muscles and pathological symptoms. Conclusions : Hand Great Yin Lung meridian muscle system showed similarity and difference to deep front arm line in anatomical train. Further studies would be needed.

• Asian-Australasian Journal of Animal Sciences
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• v.19 no.10
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• pp.1496-1502
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• 2006

Skeletal muscle contains slow and fast twitch fibers. These skeletal muscle fibers express type I and type II myosin, respectively, and these myosin isoenzymes have different ATPase activity. The aim of this study was to investigate protein profiles of bovine skeletal muscles by proteomic analysis. Fifty seven spots of distinct proteins were excised and characterized. The expression of sixteen spots was differed in longissimus dorsi muscle with a minimal 2-fold change compared to biceps femoris muscle. The majority of differentially expressed proteins belonged to metabolic regulation-related proteins such as glyceraldehyde 3-phosphate dehydrogenase, triosephosphate isomerase and carbonic anhydrase 3. The real time-PCR assay confirmed an increase or induction of specific genes: RGS12TS isoform, GAPDH, triosephosphate isomerase and carbonic anhydrase. These results suggest that the expression of metabolic proteins is under a specific control system in different bovine skeletal muscle. These observations could have significant implications for understanding the physiological regulation of bovine skeletal muscles.

• Journal of International Academy of Physical Therapy Research
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• v.12 no.2
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• pp.2323-2330
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• 2021

Background: Stroke patients have weak trunk muscle strength due to brain injury, so a single type of exercise is advised for restoring functionality. However, even after intervention, the problem still lies and it is suggested that another intervention method should be applied with exercise in order to deal with such problem. Objectives: To Investigate the effect of bridge exercise combined with functional electrical stimulation (FES) on trunk muscle activity and balance in stroke patients. Design: Randomized controlled trial. Methods: From July to August 2020, twenty stroke patients was sampled, ten patients who mediated bridge exercises combined with functional electrical stimulation were assigned to experiment group I, and ten patients who mediated general bridge exercises were assigned to experiment groupII. For the pre-test, using surface EMG were measured paralyzed rectus abdominis, erector spinae, transverse abdominis/internal oblique muscle activity, and using trunk impairment scale were measured balance. In order to find out immediate effect after intervention, post-test was measured immediately same way pre-test. Results: Change in balance didn't show significant difference within and between groups, but muscle activity of trunk was significant difference rectus abdominis and erector spinae within groups I (P<.01), also between groups was significant difference (P<.05). Conclusion: Bridge exercise combined with FES could improve trunk function more effectively than general bridge exercise due to physiological effect of functional electrical stimulation.

• Journal of muscle and joint health
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• v.26 no.3
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• pp.167-174
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• 2019

Purpose: The purpose of this study was to investigate the effects of self-efficacy and social support on health promotion behaviors of patients with stroke. Methods: A sample of 123 patients with stroke was recruited from outpatient department of a hospital. Data were collected between September and October in 2015 using Health Promoting Lifestyle Profile II (HPLP-II), the Homebound Stroke Patients' Self-efficacy, and the Multidimensional Scale of Perceived Social Support (MSPSS). Results: The mean score of HPLP-II, self-efficacy, MSPSS were 2.71 out of 4, 63.87 out of 75 and 37.91 out of 60, respectively. Multiple regression analysis demonstrated that self-efficacy and family support explained 40% of the health promotion behaviors among the stroke patients. Conclusion: The results of the study revealed that self-efficacy and family support have significantly positively correlated with health promotion behaviors. These correlates should be taken into account in the development of interventions to support patients with stoke in health behavior change.

• Proceedings of the Korean Biophysical Society Conference
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• 2003.06a
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• pp.66-66
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• 2003

In skeletal muscle cells, depolarization of the transverse tubules (T-tubules) results in Ca$\^$2+/ release from the sarcoplasmic reticulum (SR), leading to elevated cytoplasmic Ca$\^$2+/ and muscle contraction. This process has been known as excitation-contraction coupling (E-C coupling). Several proteins, such as the ryanodine receptor (RyR), triadin, junctin, and calsequestrin (CSQ), have been identified to be involved in the Ca$\^$2＋/ release process. However, the molecular interactions between the SR proteins have not been resolved. In the present study, the mechanisms of interaction between RyRl and triadin have been studied by in vitro protein binding and $\^$45/Ca$\^$2+/ overlay assays. Our data demonstrate that the intraluminal loop II of RyR1 binds to triadin in Ca$\^$2+/-independent manner. Moreover, we could not find any Ca$\^$2+/ binding sites in the loop II region. GST-pull down assay revealed that a KEKE motif of triadin, which was previously identified as a CSQ binding site (Kobayasi et al.,2000 JBC) was also a binding site for RyR1. Our results suggest that the intraluminal loop II of RyR could participate in the RyR-mediated Ca$\^$2+/ release process by offering a direct binding site to luminal triadin.

• Journal of Korean society of Dental Hygiene
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• v.21 no.1
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• pp.5-16
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• 2021

Objectives: To evaluate the impact of an oral exercise program including whole-body exercises on oral function in older people. Methods: The participants (aged ≥65 years) were divided into three groups: intervention group I (only oral exercise), intervention group II (oral exercise with whole-body exercises), and control group (no intervention). The oral health status, saliva flow rate, and oral muscle strength were evaluated. Analyses were performed to compare the three groups and identify the changes in the aforementioned parameters before and after the program. Results: The saliva flow rate significantly increased in intervention groups I and II after the program. Oral muscle strength evaluation using the Iow a oral performance instrument showed that the anterior tongue strength increased significantly in intervention group I; the posterior tongue strength and cheek strength also increased but not significantly. The anterior tongue, posterior tongue, and cheek strengths significantly increased in intervention group II. Conclusions: The oral exercise program including whole-body exercises showed positive effects on the saliva flow rate and oral strength. No significant differences were observed in the quality of life related to oral health.

• Applied Microscopy
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• v.52
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• pp.9.1-9.5
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• 2022

The compact smooth muscle 10S myosin II is a type of a monomer with folded tail and the heads bending back to interact with each other. This inactivated form is associated with regulatory and enzymatic activities affecting myosin processivity with actin filaments as well as ATPase activity. Phosphorylation by RLC can however, shuttle myosin from the inhibited 10S state to an activated 6S state, dictating the equilibrium. Multiple studies contributed by TEM have provided insights in the structural understanding of the 10S form. However, it is only recently that the true potential of Cryo-EM in deciphering the intramolecular interactions of 10S myosin state has been realized. This has led to an influx of new revelations on the 10S inactivation, unfolding mechanism and association in various diseases. This study reviews the gradual development in the structural interpretation of 10S species from TEM to Cryo-EM era. Furthermore, we discuss the utility of Cryo-EM in future myosin 10S studies and its contribution to human health.