• Title/Summary/Keyword: IDC

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Nomogram Models for Distinguishing Intraductal Carcinoma of the Prostate From Prostatic Acinar Adenocarcinoma Based on Multiparametric Magnetic Resonance Imaging

  • Ling Yang;Xue-Ming Li;Meng-Ni Zhang;Jin Yao;Bin Song
    • Korean Journal of Radiology
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    • v.24 no.7
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    • pp.668-680
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    • 2023
  • Objective: To compare multiparametric magnetic resonance imaging (MRI) features of intraductal carcinoma of the prostate (IDC-P) with those of prostatic acinar adenocarcinoma (PAC) and develop prediction models to distinguish IDC-P from PAC and IDC-P with a high proportion (IDC ≥ 10%, hpIDC-P) from IDC-P with a low proportion (IDC < 10%, lpIDC-P) and PAC. Materials and Methods: One hundred and six patients with hpIDC-P, 105 with lpIDC-P and 168 with PAC, who underwent pretreatment multiparametric MRI between January 2015 and December 2020 were included in this study. Imaging parameters, including invasiveness and metastasis, were evaluated and compared between the PAC and IDC-P groups as well as between the hpIDC-P and lpIDC-P subgroups. Nomograms for distinguishing IDC-P from PAC, and hpIDC-P from lpIDC-P and PAC, were made using multivariable logistic regression analysis. The discrimination performance of the models was assessed using the receiver operating characteristic area under the curve (ROC-AUC) in the sample, where the models were derived from without an independent validation sample. Results: The tumor diameter was larger and invasive and metastatic features were more common in the IDC-P than in the PAC group (P < 0.001). The distribution of extraprostatic extension (EPE) and pelvic lymphadenopathy was even greater, and the apparent diffusion coefficient (ADC) ratio was lower in the hpIDC-P than in the lpIDC-P group (P < 0.05). The ROC-AUCs of the stepwise models based solely on imaging features for distinguishing IDC-P from PAC and hpIDC-P from lpIDC-P and PAC were 0.797 (95% confidence interval, 0.750-0.843) and 0.777 (0.727-0.827), respectively. Conclusion: IDC-P was more likely to be larger, more invasive, and more metastatic, with obviously restricted diffusion. EPE, pelvic lymphadenopathy, and a lower ADC ratio were more likely to occur in hpIDC-P, and were also the most useful variables in both nomograms for predicting IDC-P and hpIDC-P.

IDC의 에너지 효율화지수 활용현황에 관한 고찰

  • Lee, Sang-Hak;Park, Hyeon-Gyu;Choe, Yeong-Jin
    • Information and Communications Magazine
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    • v.29 no.6
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    • pp.9-13
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    • 2012
  • IDC의 에너지 효율화 측정지수로 IDC 전체 전력 중 ICT장비에 사용한 전력의 비율을 지수화 한 PUE가 활용되고 있다. PUE는 IDC 운영자 및 관리자가 신속하게 현재의 IDC의 에너지 사용에 대한 효율성을 파악하여 에너지 효율 향상에 대한 목표수립을 가능하게 한다. 아직까지 국가적으로 명확한 IDC 에너지 효율화 기준이 없는 우리나라의 대형 IDC를 중심으로 그린그리드의 PUE를 내부 관리지표로 사용하고 있으나 적용 기준이 IDC 전용 데이터센터 위주로 작성되어 있어서 IDC 이외의 용도가 복합적으로 구성되어 있는 우리나라 IDC의 PUE를 객관적으로 측정할 수 있는 표준 마련이 시급한 실정이다. 이에 본 연구에서는 IDC 에너지 사용 측정방법과 PUE 구조 및 활용 현황에 대하여 기술하였다. 본 연구는 IDC의 에너지 효율화 측정에 활용할 수 있으며, 향후 제정될 국가적인 IDC 에너지 효율화 지수에 활용될 수 있다.

Antigenicity Study on IDC7181, a Quaternary Ammoniopropenyl Cephalosporin Possessing Two Vinyl Groups (Cephalosporin계 항생제 IDC7181에 대한 항원성시험)

  • 신지순;장호송;최은경;권운;채희열;조영민;김윤배;강종구
    • Toxicological Research
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    • v.19 no.4
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    • pp.321-324
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    • 2003
  • Antigenic potential of a novel cephalosporin, IDC7181 was examined a active systemic anaphylaxis (ASA) and passive cutaneous anaphylaxis (PCA) test, in guinea pig and mouse-rat models, respectively. In ASA test, IDC7181 induced the signs of restlessness in a few animals immunized with a high dose (100 mg/kg) of IDC7181 alone or in combination with Freund's complete adjuvant (FCA). In PCA test, only one of ten sera from the animals immunized with a high dose (100 mg/kg) of IDC7181 in the absence or presence of FCA showed positive reaction. The positive reaction, induced by IDC7181, which may be due to $\beta$-lactam ring, in ASA and PCA tests were negligible in comparison with those of traditional cephalosporins. Taken together, it is suggested that IDC7181 do not cause immunological problems in clinical dosage.

A Study on Evaluation Method of IDC in the Wire/Wireless Integrated Environment (유.무선 통합환경에서의 IDC 평가방법에 관한 연구)

  • Lee, Jea-Pyuing;Park, Jin-Seok;Lee, Man-Woo;Kim, Sun-Gohn
    • Proceedings of the Korea Contents Association Conference
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    • 2006.11a
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    • pp.599-603
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    • 2006
  • Korea Information Security Agency has executed the certification system for the information security management since 2002 and examines the conformance of the IDCs'total management system including the technical and the physical protection measure. However, this certification system has the standard only for the IDC in the wire/wireless segregated and the evaluation method for the wire/wireless integrated has not been suggested yet. This paper is on the basis of "Accumulation Information Communication Facility Secure Principle", guidelines of Wireless LAN security operation, the existing principles and recommendations of the information security and the data on IDC environment. And the paper suggests the IDC network model in the wire/wireless integrated and the IDC evaluation method.

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A Comparative Study on the Electric Power Efficiency of IDCs with AC and DC Distribution Systems (교류배전시스템과 직류배전시스템이 적용된 IDC 전력효율 비교연구)

  • Son, Sung-Yong;Mok, Hyung-Soo;Park, Kyung-Seok;Hong, Jun-Hee
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.22 no.8
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    • pp.38-44
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    • 2008
  • Internet Data Centers (IDCs), which are resulted by the rapid progress of Information Technology industry, consist of high-density digital loads with internet server systems. Introduction of DC distribution system may simplify the conventional electric power conversion system, and may result in the improvement of electric power efficiency. However, this conjecture has never been tested under Korean IDC environment. In this study, electric power efficiency of DC distribution system from KT Namsuwon IDC is contrasted with that of conventional AC distribution system from KT Bundang IDC. DC 48[V] based distribution system showed 13.2[%] higher efficiency than the conventional AC based distribution system. The further analysis with the assumption of DC 380[V] suggests efficiency improvement over 25[%] can be achieved.

Design of Integrated Control System Architecture for Green IDC (그린 IDC를 위한 통합 관제 시스템 아키텍처 설계)

  • Kim, In-Woo;Kim, Min-Su;Lee, Young-Jun;Chae, Jin-Seok
    • Proceedings of the Korean Information Science Society Conference
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    • 2011.06b
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    • pp.342-345
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    • 2011
  • 최근 전 세계는 지구온난화와 기후변화로 상징되는 '환경'위기와 고유가로 대표되는 '자원'위기를 동시에 맞이하고 있다. 정보화의 가속으로 IT 기기의 증가 및 인터넷의 통신량 증가는 IDC 운영에도 많은 영향을 주고 있다. 그 중에서도 대부분의 운영비용이 막대한 전력 소모로 인해 발생하고 있는 실정이다. 이에 따라 IDC 사업자들은 운영 경비의 비용을 줄이기 위해 IDC의 불필요한 인적, 물적 자원의 소모를 줄이며, 고성능 저비용, 저전력 장비 확보에 많은 관심을 기울이고 있다. 제안 시스템에서는 IDC의 서버와 스토리지 등의 IT 장비와 공조시스템과 전력공급시스템 등의 Non-IT 장비의 자동화 통합 관리를 통하여 인적, 물적 자원을 체계적으로 관리하여 이들의 활용성을 높이고, 나아가 IDC의 운영비용 및 효율을 고도화할 수 있도록 하였다.

Single and Four-Week Intravenous Toxicity Studies of a Novel Cephalosporin Antibiotic Agent, IDC-7181, in Rats (새로운 Cephalosporin계 항생제 IDC-7181의 랫드에 대한 단회 및 4주 반복 정맥투여 독성시험)

  • 장호송;황재식;신장우;정은용;신지순;이수해;이종성;강재훈;김기원
    • Toxicological Research
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    • v.18 no.2
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    • pp.195-203
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    • 2002
  • This study was performed to evaluate single and repeated-dose toxicities oj a new cophalosporin antibiotic agent IDC-7l81 in Sprague-Dawley rats. IDC-7181 was injected intravenously to rats at dose levels of 0, 3.2, 16, 80, 400 and 2,000 mg/kg/day for single-dose toxicity study and at dose levels of 0, 10, 50 and 250 mg/kg/day for 4-week repeated-dose toxicity study. In both studies, there were no dose-related changes in mortality clinical signs, body weight changes, food and water consumption, opthalmoscopy, organ weights, urine analysis, biochemical examination, and hematological findings of all animals treated with IDC-7l8l. Gross and histopathological findings revealed no evidence of specific toxicity related to IDC-7181. These results suggest that the intravenous maximum tolerated dose value of IDC-7181 may be over 250 mg/kg and $LD_{50}$ value may be over 2,000 mg/kg in rats.

A Development of Citrix Storagelink based on Storage Management Initiative Specification (개방형 스토리지 관리 표준기반의 Citrix Storagelink 개발)

  • Kim, Young-Hwan;Hyeon, Jae-Hun;Park, Changwon
    • Proceedings of the Korea Information Processing Society Conference
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    • 2012.11a
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    • pp.212-214
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    • 2012
  • 분산 컴퓨팅 자원의 효율적인 관리기술은 많은 기업, 연구소, 표준기관이 연구해온 분야로 최근까지도 관련된 개방형 프로젝트가 진행되고 있다. 대표적으로 DMTF는 선도적인 기업체를 중심으로 학계와 협력하여 객체지향 방법을 통한 다양한 컴퓨팅 하드웨어 및 소프트웨어 관리 시스템의 정보를 CIM기반의 객체로 정의하고 있다. 또한 SNIA에서는 DMTF의 CIM 표준을 기반으로 개방형 스토리지 관리 표준인 SMI-S 규격을 제공하고 있다. 본 논문에서는 SNIA에서 제공하는 SMI-S CIIM 스키마를 이용하여 상용 가상화 소프트웨어 인 Citrix Storagelink를 통해 Third Party 스토리지 시스템을 관리하기 위한 기술에 대해 설명한다.

A Smart Monitoring Management System Architecture Design for Modular Data Center Infra (모듈러 데이터센터 인프라를 위한 스마트 모니터링 관리 시스템 구조 설계)

  • Lee, Woo Seung;Kim, Hyun Woo;Lee, Young Hwan
    • Proceedings of the Korea Information Processing Society Conference
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    • 2013.11a
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    • pp.26-29
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    • 2013
  • 클라우드 컴퓨팅 및 빅데이터 환경에서 최근 데이터의 유동량은 폭발적으로 증가하였다. 그에 따라 대규모 IT자원 및 서비스 제공을 위한 핵심 인프라 역할을 맡고 있는 데이터센터의 수요가 급증하고 있는 추세이다. 하지만, 데이터센터의 빠른 확장 속도에 비하여 데이터센터를 통합적, 효율적으로 관리하고 모니터링 할 수 있는 시스템의 부재로 데이터센터의 빠른 유지보수, 효율적 자원관리와 고신뢰 시스템 구축이 어려운 실정이다. 또한 국내 여건상 외국의 사례와 같이 넓은 부지를 사용하여 데이터센터를 구축할 수가 없기 때문에 모듈 형태의 데이터센터 구축 연구가 절실한 상황이다. 본 논문에서는 이러한 폭발적 데이터 환경과 국내 여건을 고려한 효율적인 인프라 지원을 위한 모듈러 데이터 센터의 스마트 모니터링 관리 시스템 구조를 설계한다.

The effects of incremental dental care(IDC) on kindergarten children (유치원 아동 대상 계속구강건강관리 효과)

  • Ha, Myung-Ok;Cho, Min-Jung;Kim, Eun-Mi
    • Journal of Korean society of Dental Hygiene
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    • v.13 no.2
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    • pp.271-277
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    • 2013
  • Objectives : The purpose of this study was to evaluate the effects of incremental dental care(IDC) program on kindergarten children. Methods : The subjects were 46 kindergarten children aged 6 who wished participation in IDC program during 5 weeks at oral health center in G-college from March to May, 2012. The data of subjects were examined into oral conditions such as toothbrushing method and frequency, modified O'leary plaque index and dental caries activity before and after IDC program. The collected data were analyzed by SPSS statistical package version 19.0. Results : 1. The rolling and fones methods of toothbrushing increased from 10.8% to 91.3% after IDC program(p<.001). The change of toothbrushing frequency showed that over 3 times a day increased from 52.2% to 76.0% after IDC program(p<.01). 2. The modified O'leary plaque index of before toothbrushing education increased from 1st visit(score 32.19) to 5th visit(score 57.14) and after toothbrushing education increased from 1st visit(score 64.45) to 5th visit(score 78.27) during IDC program(p<.001). 3. As a results of dental caries activity test before and after IDC program, it was found that the bacterial numbers in S.mutans and Latobacillus reduced from 0.74, 0.70 to 0.28, 0.41 (p<.01) and the saliva buffering capacity increased from 1.50 to 2.02(p<.001). Conclusions : It is considered very necessary that IDC program should be maintained and extended to dental clinic so as to enhance the oral health state of kindergarten children.