• Title/Summary/Keyword: ICDS

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Avionics Software Data Modeling Method and Test For FACE Conformance (FACE 적합성을 위한 항공전자 소프트웨어 데이터 모델링 방안 및 검증)

  • Kyeong-Yeon, Cho;Doo-Hwan, Lee;Sang-Cheol, Cha;Jeong-Yeol, Kim
    • Journal of Aerospace System Engineering
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    • v.16 no.6
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    • pp.45-53
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    • 2022
  • The avionics industry has recently adopted an open architecture to increase software portability and reduce the development schedule and cost associated with changing hardware equipment. This paper presents a data modeling method compliant with FACE, a widely used open avionics architecture. A FACE data model is designed and implemented to output data from VOR/ILS avionics equipment. A FACE Conformance Test Suite (CTS) program is utilised to verify that the data model meets FACE standards. The proposed data modeling method is expected to improve the development schedule and cost associated with modifying communication methods and ICDs (Interface Control Documents).

Immunogenic cell death in cancer immunotherapy

  • Minji Choi;Jisoo Shin;Chae-Eun Lee;Joo-Yoon Chung;Minji Kim;Xiuwen Yan;Wen-Hao Yang;Jong-Ho Cha
    • BMB Reports
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    • v.56 no.5
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    • pp.275-286
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    • 2023
  • Cancer immunotherapy has been acknowledged as a new paradigm for cancer treatment, with notable therapeutic effects on certain cancer types. Despite their significant potential, clinical studies over the past decade have revealed that cancer immunotherapy has low response rates in the majority of solid tumors. One of the key causes for poor responses is known to be the relatively low immunogenicity of solid tumors. Because most solid tumors are immune desert 'cold tumors' with antitumor immunity blocked from the onset of innate immunity, combination therapies that combine validated T-based therapies with approaches that can increase tumor-immunogenicity are being considered as relevant therapeutic options. This review paper focuses on immunogenic cell death (ICD) as a way of enhancing immunogenicity in tumor tissues. We will thoroughly review how ICDs such as necroptosis, pyroptosis, and ferroptosis can improve anti-tumor immunity and outline clinical trials targeting ICD. Finally, we will discuss the potential of ICD inducers as an adjuvant for cancer immunotherapy.

Power, Degree and Selection Information-Aware Connected Dominating Set Construction Algorithm in Ad-hoc Wireless Networks (무선 Ad-hoc 네트워크에서 전력, 연결강도 및 이력 정보를 고려한 Connected Dominating Set 구성 방법)

  • Ha, Deok-Kyu;Song, Young-Jun;Kim, Dong-Woo;Kim, Young-Joon;Lee, In-Sung
    • The Journal of the Korea Contents Association
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    • v.9 no.8
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    • pp.49-56
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    • 2009
  • In this paper, we propose a method of energy level, node degree and selection information based CDS(Connected Dominating Set) construction algorithm for more efficient routing in ad-hoc wireless networks. Constructing CDS in ad-hoc wireless network, it is necessary to make more efficient algorithm that is faster, more simple and has low power consumption. A CDS must be minimized because nodes in the CDS consume more energy in order to handle various bypass traffics than nodes outside the set. It is better not to reconstruct CDS after constructing the most efficient CDS. To overcome this problem, we proposed the CDS construction algorithms based on EL+ND+Sel method. We compared and estimated the performance in each situation of EL + ND and EL + ND + Sel.

Thyroid Cancer Epidemiology in Iran: a Time Trend Study

  • Safavi, Ali;Azizi, Fereidoun;Jafari, Rozita;Chaibakhsh, Samira;Safavi, Amir Ali
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.407-412
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    • 2016
  • Background: Considering the rising incidence of thyroid cancer worldwide, the aim of our study was to investigate the temporal trends in the incidence of this cancer in a large population of Iranian patients. Materials and Methods: We used the Iran Cancer Data System (ICDS) Registry to assess the thyroid cancer trend from 2004 to 2010 with regard to different genders, age groups, and morphologies. To do this we analyzed the data of 10,913 new cases of thyroid cancer that occurred during these years. Results: The incidence rate (per one year) of thyroid cancer was 2.20 per 100,000 persons between 2004 and 2010 in Iran. Papillary thyroid cancer was the most common histology type, with an annual rate of 0.29 in Iran. The highest rate of prevalence in thyroid cancer was observed at the age of 45 years at the time of diagnosis. We found a female-to-male ratio of 2 in Iran. A significant decrease was detected in the trend of thyroid cancer in children <19y, which was not correlated to the trend of older patients. Conclusions: As expected, the trend of thyroid cancer increased over the 7 years, primarily contributed by papillary thyroid cancer. A rising pattern of incidence was seen in all the age groups except patients aged under 19 years.

Exploratory Factor Analysis Study on the Safety Culture of Highway Management Agencies (고속도로 관리기관의 안전문화에 대한 탐색적 요인분석 연구)

  • Jeong-Soo Seo;Kyung-Ok Jeong
    • Journal of the Korea Safety Management & Science
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    • v.26 no.1
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    • pp.55-61
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    • 2024
  • In this paper, in order to study the relationship between the safety culture of highway management agencies and disaster reduction activities (BCMS), a measurement tool was identified through previous research on safety culture, and the validity of the measurement tool was confirmed through exploratory factor analysis. I want to check. The subjects of the study were workers belonging to disaster reduction activity management system certification organizations among highway management organizations. The highway management agencies are the Korea Expressway Corporation, which manages the functional continuity of national highways nationwide, and 8 of the 21 private road agencies that manage the functional continuity of the highways. The safety culture measurement tool is an indicator that measures safety culture factors, and is reorganized by the researcher based on survey items from previous studies, with management/manager safety values and attitudes, safety communication, safety education and training, and safety regulations/management system as subfactors. A total of 24 questions were comprised of the survey tool. As a result of the study, the result of exploratory factor analysis was that the safety culture scale was extracted into four factors based on theoretical grounds, and the total cumulative variance was 80.360%. When checking the questions for each factor, it was found that all the questions loaded on the factor that was originally intended to be measured. Factor 1 is management, factor 2 is safety, and factor 3 is communication., Factor 4 was named education. Number of questions: 4 management questions, 3 safety questions, communication It consisted of 4 questions and 2 education questions.

A Study on Non-participating TDL Message Analyzer (비가입형 TDL 메시지 분석기에 관한 연구)

  • Hwang, Byoung-Han;Lee, Jung-Woong
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.11 no.3
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    • pp.290-294
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    • 2018
  • Modern warfare exhibit a NCW (Network Centric Warfare) aspect through quick situation awareness and Command and Control. And Tactical messages operate on various tactical data links (TDLs). For monitoring TDL messages processed by data link processor(DLP), message analysers are generally developed as a component during system development. In addition, in order to forward TDL messages processed by DLP to the message anayzer, the interface messages between DLP and message analysers should be defined interface control document(ICD). We propose the methods using UDP or TCP packets provided by TDL layers that are delivered to DLP without communicating directly with DLP. Depending on TDL message standards and Interface Control Documents(ICDs), we design the message analyzer which communicates with data link processor using internal messages. Using known header field information from the TDL application standard such as JREAP-C, we can quickly filter candidate packets against collected packets and use the full data size information contained in the headers to verify the completed message. Because the methods proposed in this paper do not communicate directly with DLP, the methods proposed in this paper are enable to analyze the TDL application messages such as JREAP-C or Link-K without constraints in existing methods that should be reflected in the system configuration and ICD.