• Korean Journal of Environmental Agriculture
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• v.35 no.1
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• pp.79-86
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• 2016

BACKGROUND: This study was initiated to quantitatively evaluate the effects of five heavy metals on the growth and P removal efficiencies of Alcaligenes sp., known as the Phosphorus Accumulating Organisms (PAOs). It was cultivated in the batch system with five heavy metals, such as Cd, Cu, Zn, Pb and Ni, added in single and binary mixtures, respectively.METHODS AND RESULTS: IC₅₀ (half of inhibition concentration of bacterial growth) and EC₅₀ (half of effective concentration of phosphorus removal Efficiencies) were used to quantitatively evaluate the effects of heavy metals on the growth and phosphorus removal Efficiencies of Alcaligenes sp. In addition, Additive Index Value (A.I.V.) method was used to evaluate the interactive effects between Alcaligenes sp. and heavy metals. As a result, as the five heavy metals were singly added to Alcaligenes sp., the greatest inhibitory effects on the growth and P removal efficiencies of each bacteria was observed in the cadmium (Cd). In the binary mixture treatments of heavy metals, the treatments of lowest IC₅₀ and EC₅₀ were the Cd + Cu treatment. Based on the IC₅₀ and EC₅₀ of the binary mixtures of heavy metals treatments, most interactive effects between the heavy metals were found to be antagonistic.CONCLUSION: Based on the results obtained from this study, it appears that they could provide the basic information about the toxic effects of the respective treatments of single and binary mixtures of heavy metals on the growth and P removal efficiencies of Alcaligenes sp. through further study about the characterization of functional proteins involved in toxic effects of heavy metals.

• YAKHAK HOEJI
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• v.53 no.1
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• pp.12-18
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• 2009

The aim of this study was to develop antitoxic compound for cadmium-induced cytotoxic Vero cells. These cells were divided into five groups; control group (medium only), cadmium group (cadmium only), and two experimental groups. SRB (sulphorodamine B) assay was performed to evaluate the cytotoxicity of cell organelles. After cadmium was treated on Vero cells, we determined IC50 values to examine the detoxification effects of Houttuynia cordata methanol extract and quercetin under cadmium-induced cytotoxicity. Furthermore, morphological changes were observed by the light microscope. In Vero cells, methanol extract of Houttuynia cordata, and quercetin showed inhibitory effects on cadmium-induced cytotoxicity and these detoxification effects were increased in a concentration-dependent manner. These results suggest that methanol extract and quercetin from Houttuynia cordata retain a potential antitoxic activity.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.12 no.5
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• pp.75-81
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• 2012

RFID is new recognition technology which can trace IC chip(built in information) with wireless frequency. The present RFID is used in parcel service, missing child potection system, bus card, and extensive areas. This paper proposes and designs a belongings position tracking system using RFID with GPS. The main features of the proposed system are as follows. First, the system can in real time track the lost belongings. Second, the system can provide lost belonging location information to the users. The performance evaluation of the proposed system is performed by using AVD(Android Virture Device).

• YAKHAK HOEJI
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• v.54 no.3
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• pp.151-156
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• 2010

Cytotoxicity of cadmium on NIH 3T3 fibroblasts was utilized in order to discover antitoxic compound in Galgeuntang extract in this study. Treatment groups were chosen as follows; control (medium only), $MTT_{50}$ group and five experimental groups. MTT {3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazoliumbromide} method was performed to evaluate the cytotoxicity of cell organelles and $IC_{50}$ was also measured. Accordingly we have examined the detoxification effects of Galgeuntang extract on cadmium-treated NIH 3T3 fibroblasts to observe morphological changes by the light microscopy. Galgeuntang extract showed cytoprotective effects on cadmium-induced cytotoxicity. Furthermore, Galgeuntang showed a dose-dependency in detoxication. The phenolic content of Galgeuntang ethanol extract was higher than that of water content. These results suggest that Galgeuntang extract may be used as a cytoprotective agent against cadmium (II)-mediated cytotoxicity.

• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.12
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• pp.1724-1731
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• 2009

This study was aimed to investigate the effect of phyto-extract fermented mixture (MP119) on the male sexual functions. The MP119 was evaluated for anti-impotency and anti-hypertensive effects via ACE (angiotensin converting enzyme) or PDE (phosphodiesterase) inhibition assay. $IC_{50}$ values of MP119 against ACE and PDE were 241.3${\pm}$35.5 ppm and 372.2${\pm}$33.8 ppm, respectively. To investigate the effect of testosterone expression by MP119, we performed cell media test using mouse Leydig-derived TM3 cells. Production of testosterone in TM3 cell was increased by MP119. Also, NO (nitric oxide) production of HUVEC (human umbilical vein endothelial cell) was increased when MP119 was added to the cultures. Forty male ICR mice were divided into 4 groups. MP119 was orally intubated for 7 days to group 1 and 3, and same volume of vehicle to group 2 and 4 as controls. After that, group 3 and 4 were intraperitoneally injected cadmium chloride at a single dose of 2 mg/kg. On the 8th experimental day, weights of testis, epididymis and seminal vesicle, number of sperm, concentrations of serum testosterone and cGMP were determined. The number of sperm, the concentrations of testosterone and cGMP were significantly increased in two experimental groups (group 1, 3). These results suggest that MP119 enhanced the sexual function of male mice, and could protect the sexual organs from the cadmium chloride as one of the endocrine disrupters.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.16 no.4
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• pp.33-41
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• 2006

RSA cryptosystem is of great use in systems such as IC card, mobile system, WPKI, electronic cash, SET, SSL and so on. RSA is performed through modular exponentiation. It is well known that the Montgomery multiplier is efficient in general. The critical path delay of the Montgomery multiplier depends on an addition of three operands, the problem that is taken over carry-propagation makes big influence at an efficiency of Montgomery Multiplier. Recently, the use of the Carry Save Adder(CSA) which has no carry propagation has worked McIvor et al. proposed a couple of Montgomery multiplication for an ideal exponentiation, the one and the other are made of 3 steps and 2 steps of CSA respectively. The latter one is more efficient than the first one in terms of the time complexity. In this paper, for faster operation than the latter one we use binary signed-digit(SD) number system which has no carry-propagation. We propose a new redundant binary adder(RBA) that performs the addition between two binary SD numbers and apply to Montgomery multiplier. Instead of the binary SD addition rule using in existing RBAs, we propose a new addition rule. And, we construct and simulate to the proposed adder using gates provided from SAMSUNG STD130 $0.18{\mu}m$ 1.8V CMOS Standard Cell Library. The result is faster by a minimum 12.46% in terms of the time complexity than McIvor's 2 method and existing RBAs.

• Korean Journal of Environmental Agriculture
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• v.30 no.2
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• pp.216-222
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• 2011

BACKGROUND: This study was performed to evaluate the effects of environmental factors and heavy metals on the growth and phosphorus removal capacity of Alcaligenes sp., which was well known as one of PAOs(Phosphorus Accumulating Microorganisms). METHODS AND RESULTS: The environmental factors used in this study were temperature, pH and carbon sources, and the heavy metals included Cu, Cd, Zn, As, and Ni. The growth and P removal efficiency of Alcaligenes sp. was maximal as temperature, pH, and carbon source were $25^{\circ}C$, 7, and glucose+acetate, respectively. Also, the $IC_{50}$(median inhibitory Concentration) values of Alcaligenes sp. for the Cu, Cd, Zn, As, and Ni were 5.03, 0.08, 0.73, 282.20 and 4.74 mg/L, respectively. CONCLUSION(S): Based on the results obtained from this study, it appears that the growth and P removal efficiency of Alcaligenes sp. were affected by the environment factors and at the best optimum condition for its growth and P removal efficiency, as the concentrations of heavy metals were gradually increased, its growth was correspondingly decreased.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2005.05a
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• pp.36-43
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• 2005

RFID(Radio Frequency IDentification: 라디오 주파수 인식)란 라디오 주파수를 활용해서 무선으로 사물을 인식하는 것을 의미한다. RFID 기술을 구성하는 기본 요소는 태그, 안테나, 리더 등이다. 본 연구에서는 이러한 RFID 기술의 기본 요소와 더불어 인식된 사물의 정보를 광범위하게 구축되어 있는 유${\cdot}$무선 네트워크와 연결하여 활용할 수 있는 모든 기술을 RFID 기술로 정의하였다. 비록 최근에 RFID 기술이 여러 분야에서 큰 이슈로 떠오르고 있지만, 실제 RFID 기술은 오래전인 2차 세계대전에 영국군의 자국 전투기 식별을 위해 이미 활용되고 있었다. 그러나 그 당시에는 RFID 기술의 구성요소인 태그나 리더의 값이 고가였기 때문에 특정분야에 한해 RFID 기술을 적용할 수 있었다. 그 이후에 1990년대에 이르러 RFID 기술은 가축관리, 컨테이너관리, IC 카드 등 점차 다른 분야로 적용이 확대되기 시작했다. 특히 반도체 기술의 발전이 급속도로 이루어진 1990년대 말을 기점으로 RFID 기술에 대한 연구가 활발히 이루어져, 현재에는 SCM(Supply Chain Management), 국방, 의료, 교통, 환경, 동물관리, 홈 네트워크 등 다양한 분야에 적용이 가능한 기술로 평가되고 있다. 특히, SCM에 있어서 RFID 기술 도입은 큰 파급효과가 예상되고 있다. SCM을 구성하는 기업들은 RFID 기술 도입을 통해 제품의 가시성(visibility)과 추적성(traceability)을 확보할 수 있게 된다. 기업들은 자신의 제품이 현재 어디에 있으며 어떠한 경로를 통해 그 자리에 이르렀는지를 실시간(real time)으로 확인 가능하게 된다. 미국의 월마트사(社) 와 영국의 메트로사(社) 같은 선진 유통 기업들은 실증연구를 통해 RFID 기술 도입이 비용 절감과 함께 고객 서비스 향상을 도모할 것이라는 결론을 내린 바 있다. 또한 현제 초기단계이기는 하지만 실제 RFID 기술을 도입하여 운영 중에 있다. 국내에서도 정부주도 하에 RFID 기술에 대한 연구가 활발하게 이루어지고 있으며, 지난 2004년에 유통 물류 분야의 1차 시범사업을 완료하였다. 그러나, 이러한 국내${\cdot}$외의 적극적인 도입 움직임에도 불구하고 국내에서는 아직 RFID기술 도입이 SCM(Supply Chain Management)에 있어서 구체적으로 어떠한 영향을 미치는가에 대한 연구가 거의 이루어지지 못하고 있는 실정이다. 특히 RFID 기술 도입 의사결정자에게 제공될 수 있는 정량적인 ROI 분석 모형에 관한 연구는 시급한 과제로 떠오르고 있다. 따라서 본 연구에서는 SCM 차원에서 RFID 기술 도입에 따른 ROI 분석 모형을 제시하고 적용해 보고자 한다.

• Environmental Mutagens and Carcinogens
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• v.26 no.1
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• pp.12-19
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• 2006

Cadmium, a human carcinogen, can induce toxicity in various cell lines and organs. Despite extensive research, the mechanisms of cadmium-induced cell toxicity and estrogenic potential in human are not clear. This study was performed to investigate cadmium-induced toxicity on human breast cancer cells: MCF-7 cells, an estrogen receptor (ER) positive breast cancer cells, and MDA-MB-231 cells, an ER negative breast cancer cells. MCF-7 cells was proved to be more sensitive than the other cell lines (IC50 = $50\;{\mu}M$ at MCF-7 cells and $120{\mu}M$ at MDA-MB-231). The expression of JNK and AP-1 transcription factors such as c-Jun and c-Fos dependent transcription were increased by cadmium treatment. Inhibition of ER activation by ER antagonist (tamoxifen or ICI 182,780) significantly recovered the viablity and inhibited apoptotic cell death. This suggested that cadmium-induced cell death in ER (+) cells was mediated by JNK/AP-1 pathway and this pathway was more stimulated by ER activated by cadmium. Co-treatment of antioxidants such as selenium (Se), butylated hydroxyanisole (BHA), glutathione (GSH), or N-acetyl-L-cysteine (NAC) recovered the cadmium-induced cell death in MCF-7 cells. Cadmium-induced lipid peroxidation was decreased by GSH, NAC, or BHA in MCF-7 cells. The expression of SOD protein was decreased by cadmium ($100{\mu}M$) but recovered by GSH, NAC, BHA, or Se. Our data showed that the cadmium-induced cell toxicity in human breast cancer cells could be protected by the antioxidants (Se, BHA, NAC, GSH, or NAC) and ER antagonist (tamoxifen or ICI 182,780). Therefore, toxicity of cadmium in breast cancer were mediated by oxidative stress and $ER{\alpha}$.

• Journal of Intelligence and Information Systems
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• v.20 no.4
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• pp.59-87
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• 2014

In MIS field, the researches on payment services are focused on adoption factors of payment service using behavior theories such as TRA(Theory of Reasoned Action), TAM(Technology Acceptance Model), and TPB (Theory of Planned Behavior). The previous researches presented various adoption factors according to types of payment service, nations, culture and so on even though adoption factors of identical payment service were presented differently by researchers. The payment service industry relatively has strong path dependency to the existing payment methods so that the research results on the identical payment service are different due to payment culture of nation. This paper aims to suggest a successful adoption factor of noble payment service regardless of nation's culture and characteristics of payment and prove it. In previous researches, common adoption factors of payment service are convenience, ease of use, security, convenience, speed etc. But real cases prove the fact that adoption factors that the previous researches present are not always critical to success to penetrate a market. For example, PayByPhone, NFC based parking payment service, successfully has penetrated to early market and grown. In contrast, Google Wallet service failed to be adopted to users despite NFC based payment method which provides convenience, security, ease of use. As shown in upper case, there remains an unexplained aspect. Therefore, the present research question emerged from the question: "What is the more essential and fundamental factor that should takes precedence over factors such as provides convenience, security, ease of use for successful penetration to market". With these cases, this paper analyzes four cases predicted on the following hypothesis and demonstrates it. "To successfully penetrate a market and sustainably grow, new payment service should find non-customer of the existing payment service and provide noble payment method so that they can use payment method". We give plausible explanations for the hypothesis using multiple case studies. Diners club, Danal, PayPal, Square were selected as a typical and successful cases in each category of payment service. The discussion on cases is primarily non-customer analysis that noble payment service targets on to find the most crucial factor in the early market, we does not attempt to consider factors for business growth. We clarified three-tier non-customer of the payment method that new payment service targets on and elaborated how new payment service satisfy them. In case of credit card, this payment service target first tier of non-customer who can't pay for because they don't have any cash temporarily but they have regular income. So credit card provides an opportunity which they can do economic activities by delaying the date of payment. In a result of wireless phone payment's case study, this service targets on second of non-customer who can't use online payment because they concern about security or have to take a complex process and learn how to use online payment method. Therefore, wireless phone payment provides very convenient payment method. Especially, it made group of young pay for a little money without a credit card. Case study result of PayPal, online payment service, shows that it targets on second tier of non-customer who reject to use online payment service because of concern about sensitive information leaks such as passwords and credit card details. Accordingly, PayPal service allows users to pay online without a provision of sensitive information. Final Square case result, Mobile POS -based payment service, also shows that it targets on second tier of non-customer who can't individually transact offline because of cash's shortness. Hence, Square provides dongle which function as POS by putting dongle in earphone terminal. As a result, four cases made non-customer their customer so that they could penetrate early market and had been extended their market share. Consequently, all cases supported the hypothesis and it is highly probable according to 'analytic generation' that case study methodology suggests. We present for judging the quality of research designs the following. Construct validity, internal validity, external validity, reliability are common to all social science methods, these have been summarized in numerous textbooks(Yin, 2014). In case study methodology, these also have served as a framework for assessing a large group of case studies (Gibbert, Ruigrok & Wicki, 2008). Construct validity is to identify correct operational measures for the concepts being studied. To satisfy construct validity, we use multiple sources of evidence such as the academic journals, magazine and articles etc. Internal validity is to seek to establish a causal relationship, whereby certain conditions are believed to lead to other conditions, as distinguished from spurious relationships. To satisfy internal validity, we do explanation building through four cases analysis. External validity is to define the domain to which a study's findings can be generalized. To satisfy this, replication logic in multiple case studies is used. Reliability is to demonstrate that the operations of a study -such as the data collection procedures- can be repeated, with the same results. To satisfy this, we use case study protocol. In Korea, the competition among stakeholders over mobile payment industry is intensifying. Not only main three Telecom Companies but also Smartphone companies and service provider like KakaoTalk announced that they would enter into mobile payment industry. Mobile payment industry is getting competitive. But it doesn't still have momentum effect notwithstanding positive presumptions that will grow very fast. Mobile payment services are categorized into various technology based payment service such as IC mobile card and Application payment service of cloud based, NFC, sound wave, BLE(Bluetooth Low Energy), Biometric recognition technology etc. Especially, mobile payment service is discontinuous innovations that users should change their behavior and noble infrastructure should be installed. These require users to learn how to use it and cause infra-installation cost to shopkeepers. Additionally, payment industry has the strong path dependency. In spite of these obstacles, mobile payment service which should provide dramatically improved value as a products and service of discontinuous innovations is focusing on convenience and security, convenience and so on. We suggest the following to success mobile payment service. First, non-customers of the existing payment service need to be identified. Second, needs of them should be taken. Then, noble payment service provides non-customer who can't pay by the previous payment method to payment method. In conclusion, mobile payment service can create new market and will result in extension of payment market.