• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.15 no.7
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• pp.692-697
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• 2004

OFDM system is very useful for the multi-path channel and highly bandwidth-efficient system. However, OFDM signal shows the high PAPR so that nonlinear distortion can happen in the HPA(high power amplifier). This paper studies BER performance variation according to IBO(input back off) values when the predistorter is used fur the compensation for the HPA nonlinearity. In case of the SSPA(solid state power amplifier) of nonlinearity parameter p=0.5 and IBO=0㏈, the system with predistorter is poorer than the one without predistorter. But this situation is inverted, if IBO is increased from 0㏈ to 3㏈. So, we can find that there is a threshold value of IBO for the predistorter to effectively compensate for the nonlinear SSPA when the sub-carrier number and p value are changed.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.15 no.3
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• pp.319-325
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• 2004

FHMA(frequency hopping multiple access) communication system has good performance for the LPI and AJ(low probability of intercept and anti-jamming) application. However, high PAPR(peak to average power ratio) happens in the base-station or the repeater system because of a large number of users. In general, predistorter is used to complete the HPA(high power amplifier) nonlinear characteristics. This paper analyzes BER performance when magnitude of IBO(input back oft) and the number of user are considered as the system parameters. In case of the SSPA(solid state power amplifier), the predistorter does not always work as a complete nonlinear compensator. We find that there is a minimum value of IBO for the predistorter to compensate for the nonlinear SSP A, which is changed as the number of user. If IBO is lower than 6 ㏈ at the user number of 16 and p=1, the system with predistorter is poorer than the one without predistorter. Only when the IBO is over 6 ㏈, predistorter does work as a nonlinear compensator. We call it as cross-over IBO value. TWTA improves the more compensation performance than SSPA because characteristic AM/AM of TWTA has more nonlinear than SSPA. At the BER=10$\^$-3/, there are SNR power gains of about 2.5 ㏈ and 3 ㏈ due to the predistorter when the numbers of users are 16 and 32, respectively.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2004.11a
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• pp.124-128
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• 2004

We have assessed amyloid ${\beta}-peptide$ $(A{\beta})-induced$ neurotoxicity in primary neurons and organotypic hippocampal slice cultures (OHC) in rat. Exposing cultured hippocampal and cerebellar granule neurons to $A{\beta}$ resulted in a decrease of MTT reduction, and in destruction of neuronal integrity. Treatment of these neurons with tunicamycin, an inhibitor of N-glycosylation in the endoplasmic reticulum (ER), also decreased MTT reduction in these neurons. S-allyl-L-cysteine (SAC), an active organosulfur compound in aged garlic extract, protected hippocampal but not cerebellar granule neurons against $A{\beta}$- or tunicamycin-induced toxicity. In the hippocampal neurons, protein expressions of casapse-12 and GRP 78 were significantly increased after $A{\beta}_{25-35}$ or tunicamycin treatment. The increase in the expression of caspase-12 was suppressed by simultaneously adding $1{\mu}M$ SAC in these neurons. In contrast, in the cerebellar granule neurons, the expression of caspase-12 was extremely lower than that in the hippocampal neurons, and an increase in the expression by $A{\beta}_{25-35}$ or tunicamycin was not detected. In OHC, ibotenic acid (IBO), a NMDA receptor agonist, induced concentration-dependent neuronal death. When $A{\beta}$ was combined with IBO, there was more intense cell death than with IBO alone. SAC protected neurons in the CA3 area and the dentate gyrus (DG) from the cell death induced by IBO in combination with $A{\beta}$, although there was no change in the CA1 area. Although protein expression of casapse-12 in the CA3 area and the DG was significantly increased after the simultaneous treatment of AI3 and IBO, no increase in the expression was observed in the CA1 area. These results suggest that SAC could protect against the neuronal cell death induced by the activation of caspase-12 in primary cultures and OHC. It is also suggested that multiple mechanisms may be involved in neuronal death induced by AI3 and AI3 in combination with IBO.

• The Journal of the Korea Contents Association
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• v.5 no.1
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• pp.201-208
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• 2005

Tn this paper, we evaluate the peak-to-average power ratio (PAPR) performance in a space-time block code (STBC) multi-input multi-output orthogonal frequency division multiplexing (MIMO-OFDM) system using selected mapping (SLM) and partial transmit sequences (PTS) approaches. SLM and PTS methods are used to decrease the nonlinear distortion and to improve the power efficiency of the nonlinear high power amplifier(HPA) in the MIMO-OFDM system. In simulation result, when compared with the existing MIMO-OFDM system using QPSK, the PTS method reduces the PAPR about 5dB while the SLM method can reduce about 3.5 dB. Also, we find the BER performance of the MIMO-OFDM system with and without the predistorter in front of the HPA. When the predistorter is used, the input back-off (IBO) of 4 dB is required in the PTS method, and IBO of 6 dB in the SLM method to closely conform to the linear amplifier. If the method of improving the PAPR is not used, the value of IBO of 8 dB is required.

• The Korean Journal of Physiology and Pharmacology
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• v.23 no.6
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• pp.483-491
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• 2019

Cordycepin exerts neuroprotective effects against excitotoxic neuronal death. However, its direct electrophysiological evidence in Alzheimer's disease (AD) remains unclear. This study aimed to explore the electrophysiological mechanisms underlying the protective effect of cordycepin against the excitotoxic neuronal insult in AD using whole-cell patch clamp techniques. ${\beta}$-Amyloid ($A{\beta}$) and ibotenic acid (IBO)-induced injury model in cultured hippocampal neurons was used for the purpose. The results revealed that cordycepin significantly delayed $A{\beta}$ + IBO-induced excessive neuronal membrane depolarization. It increased the onset time/latency, extended the duration, and reduced the slope in both slow and rapid depolarization. Additionally, cordycepin reversed the neuronal hyperactivity in $A{\beta}$ + IBO-induced evoked action potential (AP) firing, including increase in repetitive firing frequency, shortening of evoked AP latency, decrease in the amplitude of fast afterhyperpolarization, and increase in membrane depolarization. Further, the suppressive effect of cordycepin against $A{\beta}$ + IBO-induced excessive neuronal membrane depolarization and neuronal hyperactivity was blocked by DPCPX (8-cyclopentyl-1,3-dipropylxanthine, an adenosine $A_1$ receptor-specific blocker). Collectively, these results revealed the suppressive effect of cordycepin against the $A{\beta}$ + IBO-induced excitotoxic neuronal insult by attenuating excessive neuronal activity and membrane depolarization, and the mechanism through the activation of $A_1R$ is strongly recommended, thus highlighting the therapeutic potential of cordycepin in AD.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.14 no.6
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• pp.543-549
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• 2003

It is important to consider the nonlinear effects of the HPA(High Power Amplifier) in the OFDM communication systems and other digital communication systems as well. In this paper, we investigate a new performance figure-of$.$merit(D) that reflects both power and spectrum efficiencies. The performance figure-of-merit is expressed to include the spectrum and power efficiencies that depend on the magnitude of IBO(Input Backoff) and the number of subcarriers. So, we analyze the variation characteristics of the power efficiency and spectrum efficiency which has the tradeoff relationship.

• The Journal of the Korea Contents Association
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• v.17 no.12
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• pp.525-536
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• 2017

One of Africa's most accomplished writer, Chinua Achebe is not only known to have to contributed to writing a renowned folk literature but to contributing to the expansion of the English language. This research paper seeks to explore Achebe's most widely read novel "Things Fall Apart" and his 1 other novel and analyze how the incorporation and purposeful use of Ibo words, proverbs and phrases contribute to not only conveying the rich African experience but expanding the English language.

• Journal of The Korean Association For Science Education
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• v.18 no.4
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• pp.627-633
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• 1998

Achievements of Korean delegate students who attend on the 9th International Biology Olympiad(IBO) were compared with those of IBO participants for the 4th, 5th and 7th theoretical tests. It was predicted that four Korean delegates won medals in the 9th IBO on the basis of the average percentages of correct answer and the shifting patterns of achievement. And achievemens of four delegates during delegates training period were compared with that in the 9th IBO. Mean perecntages of theoretical part of them were 78.15%, 77.16%, 80.97% and 76.99% respectively, and total mean percentage was 78.32%. Their achievement was level for silver medalist. It was 86.56% on the average that they had achieved in the 9th IBO. This result was more than achievement in delegates training. Their percentages of achievement order were 90.84%, 97.71%, 82.44% and 70.99% respectively. One of them won gold medal and the others won silver medals. It was needed to develop effective teaching program for biology gifted-students and training preparing for IBO.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38A no.1
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• pp.79-87
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• 2013

A new modulation technique - correlative encoded FSK (CEFSK) - for use in power and bandwidth limited digital communication system is proposed. CEFSK is free of ISI and generates output signals which have a smooth and continuous phase transition and a reduced envelope fluctuation by keeping correlation between amplitude and phases of two subsequent symbols. In comparison to conventional one-bit differential detected (1DD) GFSK, the performance of the 1DD-CEFSK in a non-linearly amplified (NLA) channel impaired by additive white Gaussian noise (AWGN), ISI and IM, is analyzed via computer simulation. The simulation result shows that, in an NLA single-channel, 1DD-CEFSK provides a signal-to-noise ratio (SNR) advantage of up to 1.2dB and 0.8dB at BER of $1{\times}10^{-4}$ when input back-off (IBO) of HPA is -1.0dB and -3.0dB, respectively. For the same channel environment with multi-channel, 1DD-CEFSK outperforms 1DD-GFSK by 1.1dB in SNR, regardless of the value of IBO.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.19 no.1
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• pp.64-69
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• 2005

In this paper, we analyzed the nonlinear performance on the DS/CDMA Communication System. At the $BER=10^{-4}$, uniform chip waveforms have similar performance in the linear channel. However, non-uniform chip waveforms have about more 0.5[dB] power gain than the conventional raised-cosine chip waveforms. In the nonlinear HPA, non-uniform chip waveforms have worse BER performance than the uniform chip waveforms because of the high PAPR. In other words, non-uniform chip waveforms show similar performance as uniform chip waveforms if IBO (input back on) of 15[dB] is given.