• Anatomy and Cell Biology
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• 제57권1호
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• pp.105-118
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• 2024

The world has witnessed tremendous advancements in nano-base applications. Zinc oxide nanoparticles (ZON) are widely used in food industry and medicine. Although their application is of important value, they may cause toxicity to body tissues. Peripheral blood mononuclear cells (PBMCs) proved its efficacy in tissue regeneration especially when it is preconditioned by activated platelet supernatant (APS). The aim of this study is to evaluate the effect of ZON on the gastric mucosa and the therapeutic role of the PBMCs preconditioned by APS in rats. Ten rats were donors and fifty rats were recipients. The recipients were divided into; control group, ZON group (10 mg/kg/day orally for five days) and preconditioned PBMCs group (1×10⁷ once intravenously 24 hours after ZON). Gastric specimens were processed for histological, immunohistochemical, biochemical and quantitative real-time polymerase chain reaction studies. ZON group showed marked structural changes in the gastric mucosa. There was desquamation or deep ulceration of the epithelium. Cytoplasmic vacuoles and pyknotic nuclei were in glandular cells. Reduced proliferating cell nuclear antigen and increased tumor necrosis factor-α were in epithelial cells. There were significant elevation in malondialdahyde and reduction in glutathione, superoxide dismutase, and catalase. Enhancement in mRNA expression of nuclear factor kappa-B and cyclooxygenase-2 was detected. The preconditioned PBMCs group showed significant improvement of all parameters. So, ZON had cytotoxic effects on the gastric mucosa and the preconditioned PBMCs had a therapeutic effect on gastric mucosal damage after ZON.

• Applied Microscopy
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• 제47권3호
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• pp.121-125
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• 2017

This study deals the prediction of temperature effect on low-frequency dispersion of alternating current (AC) conductivity spectra of composite materials based on copolymer reinforced with carbon black (CB) particles. A sample of ethylene butylacrylate loaded with 13% of CB particles were prepared and investigated using the impedance spectroscopy representation in the frequency range from 40 Hz to 0.1 MHz and temperature range from $20^{\circ}C$ to $125^{\circ}C$. The dielectric constant, ${\varepsilon}^{\prime}$, and dielectric losses, ${\varepsilon}^{{\prime}{\prime}}$, were found to decrease with increasing frequency. The frequency dependence of the AC conductivity follows the universal power law with a large deviation in the high frequency region, the positive temperature coefficient in resistivity effect has been observed below the melting temperature which makes this composite potentially remarkable for industrial applications.

• Structural Engineering and Mechanics
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• 제67권5호
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• pp.517-525
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• 2018

In this study, we investigate the vibration of single-walled carbon nanotubes embedded in a polymeric matrix using nonlocal elasticity theories with account arbitrary boundary conditions effects. A Winkler type elastic foundation is employed to model the interaction of nanobeam and the surrounding elastic medium. Influence of all parameters such as nonlocal small-scale effects, Winkler modulus parameter, vibration mode and aspect ratio of nanobeam on the vibration frequency are analyzed and discussed. The mechanical properties of carbon nanotubes and polymer matrix are treated and an analytical solution is derived using the governing equations of the nonlocal Euler-Bernoulli beam models. Solutions have been compared with those obtained in the literature and The results obtained show that the non-dimensional natural frequency is significantly affected by the small-scale coefficient, the vibrational mode number and the elastic medium.

• Smart Structures and Systems
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• 제19권3호
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• pp.289-297
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• 2017

This work presents a simplified higher order shear deformation theory (HSDT) for thermal buckling analysis of cross-ply laminated composite plates. Unlike the existing HSDT, the present one has a new displacement field which introduces undetermined integral terms and contains only four unknowns. Governing equations are derived from the principle of the minimum total potential energy. The validity of the proposed theory is evaluated by comparing the obtained results with their counterparts reported in literature. It can be concluded that the proposed HSDT is accurate and simple in solving the thermal buckling behavior of laminated composite plates.

• Structural Engineering and Mechanics
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• 제60권4호
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• pp.693-705
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• 2016

Functionally graded material (FGM) plates can be bonded to the soffit of a beam as a means of retrofitting the RC beam. In such plated beams, tensile forces develop in the bonded plate and these have to be transferred to the original beam via interfacial shear and normal stresses. In this paper, an interfacial stress analysis is presented for simply supported concrete beam bonded with a functionally graded material FGM plate. This new solution is intended for application to beams made of all kinds of materials bonded with a thin plate, while all existing solutions have been developed focusing on the strengthening of reinforced concrete beams, which allowed the omission of certain terms. It is shown that both the normal and shear stresses at the interface are influenced by the material and geometry parameters of the composite beam. This research is helpful for the understanding on mechanical behavior of the interface and design of the FGM-RC hybrid structures.

• Advances in materials Research
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• 제4권1호
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• pp.31-44
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• 2015

This paper presents a simple n-order four variable refined theory for buckling analysis of functionally graded plates. By dividing the transverse displacement into bending and shear parts, the number of unknowns and governing equations of the present theory is reduced, and hence, makes it simple to use. The present theory is variationally consistent, uses the n-order polynomial term to represent the displacement field, does not require shear correction factor, and eliminates the shear stresses at the top and bottom surfaces. A power law distribution is used to describe the variation of volume fraction of material compositions. Equilibrium and stability equations are derived based on the present n-order refined theory. The non-linear governing equations are solved for plates subjected to simply supported boundary conditions. The thermal loads are assumed to be uniform, linear and non-linear distribution through-the-thickness. The effects of aspect and thickness ratios, gradient index, on the critical buckling are all discussed.

• Coupled systems mechanics
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• 제4권1호
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• pp.99-114
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• 2015

In this paper, a refined exponential shear deformation beam theory is developed for bending analysis of functionally graded beams. The theory account for parabolic variation of transverse shear strain through the depth of the beam and satisfies the zero traction boundary conditions on the surfaces of the beam without using shear correction factors. Contrary to the others refined theories elaborated, where the stretching effect is neglected, in the current investigation this so-called "stretching effect" is taken into consideration. The material properties of the functionally graded beam are assumed to vary according to power law distribution of the volume fraction of the constituents. Based on the present shear deformation beam theory, the equations of motion are derived from Hamilton's principle. Analytical solutions for static are obtained. Numerical examples are presented to verify the accuracy of the present theory.

• Structural Engineering and Mechanics
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• 제54권5호
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• pp.923-936
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• 2015

In this paper, a simple n-order refined theory based on neutral surface position is developed for bending and frees vibration analyses of functionally graded beams. The present theory is variationally consistent, uses the n-order polynomial term to represent the displacement field, does not require shear correction factor, and gives rise to transverse shear stress variation such that the transverse shear stresses vary parabolically across the thickness satisfying shear stress free surface conditions. The governing equations are derived by employing the Hamilton's principle and the physical neutral surface concept. The accuracy of the present solutions is verified by comparing the obtained results with available published ones.

• Steel and Composite Structures
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• 제20권2호
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• pp.413-429
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• 2016

A theoretical method to predict the interfacial stresses in the adhesive layer of reinforced concrete beams strengthened with externally bonded carbon fiber-reinforced polymer (CFRP) plate is presented. The analysis provides efficient calculations for both shear and normal interfacial stresses in reinforced concrete beams strengthened with composite plates, and accounts for various effects of Poisson's ratio and Young's modulus of adhesive. Such interfacial stresses play a fundamental role in the mechanics of plated beams, because they can produce a sudden and premature failure. The analysis is based on equilibrium and deformations compatibility approach developed by Tounsi. In the present theoretical analysis, the adherend shear deformations are taken into account by assuming a parabolic shear stress through the thickness of both the reinforced concrete beam and bonded plate. The paper is concluded with a summary and recommendations for the design of the strengthened beam.

• Earthquakes and Structures
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• 제13권1호
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• pp.9-15
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• 2017

In this paper, the influence of the rotational component, about a vertical axis, of earthquake ground motion on the response of building structures subjected to seismic action is considered. The torsional component of ground motion is generated from the records of translational components. Torsional component of ground motion is then, together with translational components, applied in numerical linear dynamic analysis of different reinforced concrete framed structure of three stories buildings. In total, more than 40 numerical models were created and analyzed. The obtained results show clearly the dependence of the effects of the torsional seismic component on structural system and soil properties. Thus, the current approach in seismic codes of accounting for the effects of accidental torsion due to the torsional ground motion, by shifting the center of mass, should be reevaluated.