• Korean Journal of Veterinary Service
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• v.30 no.3
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• pp.321-327
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• 2007

This is a case report on the occurrence of inclusion body hepatitis (IBH) and infectious bursal disease (IBD) among the broilers in a local farm located in Wanju, Jeollabukdo. Mostly IBH could be caused by adenovirus if the bird's immune system was first weakened by exposure to immunosupressive agents such as infectious bursal disease virus (IBDV) and chicken anemia virus (CIAV). However IBH primary occurred before IBD in this case. And recent work has demonstrated that virulent adenovirus alone can produce the disease.

• Monthly Korean Chicken
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• v.14 no.11
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• pp.127-131
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• 2008

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2012.04a
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• pp.163-164
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• 2012

• Journal of Veterinary Science
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• v.22 no.4
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• pp.42.1-42.16
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• 2021

Background: Inclusion body hepatitis (IBH) is an economically important viral disease primarily affecting broiler and breeder chickens. All 12 serotypes of fowl adenovirus (FAdV) can cause IBH. Objectives: To characterize FAdV isolates based on phylogenetic analysis, and to study the pathogenicity of FAdV-8b in specific-pathogen-free (SPF) chickens following virus inoculation via oral and intramuscular (IM) routes. Methods: Suspected organ samples were subjected to virus isolation and polymerase chain reaction (PCR) for FAdV detection. Hexon gene sequencing and phylogenetic analysis were performed on FAdV-positive samples for serotype identification. One FAdV-8b isolate, UPM/FAdV/420/2017, was selected for fiber gene characterization and pathogenicity study and was inoculated in SPF chickens via oral and IM routes. Results: The hexon gene phylogenetic analysis revealed that all isolates belonged to FAdV-8b. The fiber gene-based phylogenetic analysis of isolate UPM/FAdV/420/2017 supported the grouping of that isolate into FAdV species E. Pathogenicity study revealed that, chickens infected with UPM/FAdV/420/2017 via the IM route had higher clinical score values, higher percent mortality, higher degree of the liver lesions, higher antibody response (p < 0.05), and higher virus shedding amounts (p < 0.05) than those infected via the oral route. The highest virus copy numbers were detected in liver and gizzard. Conclusions: FAdV-8b is the dominant FAdV serotype in Malaysia, and pathogenicity study of the FAdV-8b isolate UPM/FAdV/420/2017 indicated its ability to induce IBH in young SPF chickens when infected via oral or IM routes.

• Korean Journal of Poultry Science
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• v.37 no.3
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• pp.255-263
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• 2010

Inclusion body hepatitis-hydropericardium syndrome (IBH-HPS) is an acute viral disease usually found in broilers aged from 3 to 5 weeks and causes up to 75% mortality. Among the 12 serotypes of fowl adenovirus group 1, serotype-4 (FAdV-4) was identified as a primary agent of IBH-HPS and was usually isolated in IBH-HPS cases in Korea since 2007. To prevent these IBH-HPS outbreaks in Korea, we developed the FAdV-4 inactivated vaccine using Korean isolate (ADL070244) and evaluated the efficacy of this vaccine. For the efficacy test, 2-week-old specific-pathogen-free (SPF) chickens intramuscularly inoculated with 1 or 2 dose of inactivated vaccine were used and challenged with FAdV-4 through either intramuscular or oral route at 2 weeks after vaccination. The vaccine induced good seroconversion which was confirmed by agar gel precipitation (AGP) test. In addition, the vaccine could decrease the FAdV-4 detection rate and histological lesion severity such as lymphocyte infiltration and necrosis in the liver comparing with those of non-vaccination group. Based on the current results, the developed FAdV-4 inactivated vaccine in this study was effective in the terms of reduction of virus detection rate and histological lesions severity. However, it was difficult to confirm the efficacy of the vaccine clearly because of no mortality and clinical signs in the non-vaccinated group after challenge. Therefore, we need further study to develop a standard challenged model system which could clearly evaluate the efficacy of the vaccines for FAdV-4.

• Journal of Electrical Engineering and Technology
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• v.13 no.5
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• pp.2086-2098
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• 2018

Security plays a vital role and is the key challenge in Mobile Ad-hoc Networks (MANET). Infrastructure-less nature of MANET makes it arduous to envisage the genre of topology. Due to its inexhaustible access, information disseminated by roaming nodes to other nodes is susceptible to many hazardous attacks. Intrusion Detection and Prevention System (IDPS) is undoubtedly a defense structure to address threats in MANET. Many IDPS methods have been developed to ascertain the exceptional behavior in these networks. Key issue in such IDPS is lack of fast self-organized learning engine that facilitates comprehensive situation awareness for optimum decision making. Proposed "Intelligent Behavioral Hybridized Intrusion Detection and Prevention System (IBH_IDPS)" is built with computational intelligence to detect complex multistage attacks making the system robust and reliable. The System comprises of an Intelligent Client Agent and a Smart Server empowered with fuzzy inference rule-based service engine to ensure confidentiality and integrity of network. Distributed Intelligent Client Agents incorporated with centralized Smart Server makes it capable of analyzing and categorizing unethical incidents appropriately through unsupervised learning mechanism. Experimental analysis proves the proposed model is highly attack resistant, reliable and secure on devices and shows promising gains with assured delivery ratio, low end-to-end delay compared to existing approach.

• Journal of Korean Neurosurgical Society
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• v.60 no.2
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• pp.211-219
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• 2017

Objective : This study aimed to compare the clinical and radiologic outcomes of patients with subaxial cervical injury who underwent anterior cervical discectomy and fusion (ACDF) with autologous iliac bone graft or polyetheretherketone (PEEK) cages using demineralized bone matrix (DBM). Methods : From January 2005 to December 2010, 70 patients who underwent one-level ACDF with plate fixation for post-traumatic subaxial cervical spinal injury in a single institution were retrospectively investigated. Autologous iliac crest grafts were used in 33 patients (Group I), whereas 37 patients underwent ACDF using a PEEK cage filled with DBM (Group II). Plain radiographs were used to assess bone fusion, interbody height (IBH), segmental angle (SA), overall cervical sagittal alignment (CSA, C2-7 angle), and development of adjacent segmental degeneration (ASD). Clinical outcome was assessed using a visual analog scale (VAS) for pain and Frankel grade. Results : The mean follow-up duration for patients in Group I and Group II was 28.9 and 25.4 months, respectively. All patients from both groups achieved solid fusion during the follow-up period. The IBH and SA of the fused segment and CSA in Group II were better maintained during the follow-up period. Nine patients in Group I and two patients in Group II developed radiologic ASD. There were no statistically significant differences in the VAS score and Frankel grade between the groups. Conclusion : This study showed that PEEK cage filled with DBM, and plate fixation is at least as safe and effective as ACDF using autograft, with good maintenance of cervical alignment. With advantages such as no donor site morbidity and no graft-related complications, PEEK cage filled with DBM, and plate fixation provide a promising surgical option for treating traumatic subaxial cervical spine injuries.

• The Journal of Korean Society for Radiation Therapy
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• v.31 no.2
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• pp.43-49
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• 2019

Purpose: This study examined changes in the position of the heat and lungs depending on the patient's breathing method during left breast cancer radiotherapy and used treatment plans to compare the resulting radiation dose. Materials and methods: The participants consisted of 10 patients with left breast cancer. A CT simulator(SIMENS SOMATOM AS, Germany) was used to obtain images when using three different breathing methods: free breathing(FB), deep inspiration breath hold(DIBH with Abches, DIBH), inspiration breath hold(IBH with CPAP, CPAP). A Ray Station(5.0.2.35, Sweden) was used for treatment planning, the treatment method was volumetric modulated arc therapy (VMAT) with one partial arc of the same angle, and the prescribed dose to the planning target volume (PTV) was a total dose of 50Gy(2Gy/day). In treatment plan analysis, the 95% dose (D95) to the PTV, the conformity index(CI), and the homogeneity index (HI) were compared. The lungs, heart, and left anterior descending artery (LAD) were selected as the organs at risk(OARs). Results: The mean volume of the ipsilateral lung for FB, DIBH, and CPAP was 1245.58±301.31㎤, 1790.09±362.43 ㎤, 1775.44±476.71 ㎤. The mean D95 for the PTV was 46.67±1.89Gy, 46.85±1.72Gy, 46.97±23.4Gy, and the mean CI and HI were 0.95±0.02, 0.96±0.02, 0.95±0.02 and 0.91±0.01, 0.90±0.01, 0.92±0.02. The V20 of Whole Lung was 10.74±4.50%, 8.29±3.14%, 9.12±3.29% and The V20 of the ipsilateral lung was 20.45±8.65%, 17.18±7.04%, 18.85±7.85%, the Dmean of the heart was 7.82±1.27Gy, 6.10±1.27Gy, 5.67±1.56Gy, and the Dmax of the LAD was 20.41±7.56Gy, 14.88±3.57Gy, 14.96±2.81Gy. The distance from the thoracic wall to the LAD was measured to be 11.33±4.70mm, 22.40±6.01mm, 20.14±6.23mm. Conclusion: During left breast cancer radiotherapy, the lung volume was 46.24% larger for DIBH than for FB, and 43.11% larger for CPAP than FB. The larger lung volume increases the distance between the thoracic wall and the heart. In this way, the LAD, which is one of the nearby OARs, can be more effectively protected while still satisfying the treatment plan. The lung volume was largest for DIBH, and the distance between the LAD and thoracic wall was also the greatest. However, when performing treatment with DIBH, the intra-fraction error cannot be ignored. Moreover, communication between the patient and the radiotherapist is also an important factor in DIBH treatment. When communication is problematic, or if the patient has difficulty holding their breath, we believe that CPAP could be used as an alternative to DIBH. In order to verify the clinical efficacy of CPAP, it will be necessary to perform long-term follow-up of a greater number of patients.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.57-57
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• 2023

최근 심각한 기후변화로 인한 호우, 태풍 등 기상현상의 변화로 다양한 재해가 발생하고 그로 인한 피해 규모도 커지고 있다. 현재 우리나라의 호우 재해에 대한 예보는 단순히 강수량, 강설량, 바람의 강도 등을 전달해 주고 있는데, 이러한 정보 전달의 형태는 그로 인한 피해 규모를 예측하기 어렵다. 본 시스템은 현재의 단순한 수치만을 보여주는 예보에서 호우가 어느 지역에 어떠한 영향을 미치는지에 대한 정보를 전달한다. 시간대별 격자단위(1km×1km)로 구획하여 그 영향이클 것이라고 예상되는 9개 분야(생활, 도로, 농업, 편의, 공업, 의료복지, 교육연구. 축산업, 공용)의 정보를 전달 해 줌으로써 경제적, 산업적 측면에서 재난으로 인한 피해를 최소화할 수 있도록 하였다. GIS와 호우위험영향도 분석결과를 제공하는 플랫폼이며 주요 기능은 종합위험등급 현황을한 눈에 볼 수 있는 GIS 대쉬보드 상황판과 IBH-HR(예측강우분석), IBF-G(수문분석), IBF-PRA(리스크 분석) 3개의 분석 모듈 그리고 분석 모듈을 통해 도출된 분석결과를 관리하는 ARM(분석이력관리)으로 구성되었다. 다양한 콘텐츠 서비스로 호우 영향정보의 활용성이 클 것으로 기대된다.