• Asian-Australasian Journal of Animal Sciences
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• 제23권9호
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• pp.1145-1151
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• 2010

The objective of this work was to analyze the relationship between ovine major histocompatibility complex (MHC) DRB1 gene polymorphism and genetic resistance to hydatidosis in Kazakh sheep. The Ovar (ovine MHC) class II DRB1 second exon was amplified by polymerase chain reaction (PCR) from DNA samples of 702 Kazakh sheep, including 302 sheep with hydatidosis and 400 health controls. PCR products were characterized by the restriction fragment length polymorphism (RFLP) technique using five restriction enzymes, i.e., MvaI, HaeIII, SacI, SacII and Hin1I, yielding 14 alleles and 28 genotypes. Comparing the frequency of genotypes in hydatidosis sheep with the control group, it was found that the genotype frequencies of MvaIbc, Hin1Iab, SacIIab, HaeIIIde, HaeIIIdf and HaeIIIdd in control sheep were significantly (p<0.01) higher than in hydatidosis sheep, indicating that a significant correlation existed between these genotypes and resistance to hydatidosis. Genotype frequencies of MvaIbb, SacIIaa, Hin1Ibb and HaeIIIef in sheep with hydatidosis were extremely significantly (p<0.01) higher than in the control group, and the genotype frequency of HaeIIIab was significantly higher (p<0.05), indicating that a marked correlation existed between these genotypes and susceptibility to hydatidosis. By way of analyzing haplotype with these resistant genotypes, the hydatidosis resistant haplotype MvaIbc-SacIIab-Hin1Iab of Kazakh sheep was screened out, and then verified through artificial hydatid infection in sheep. The results indicated that the infection rate of sheep with the resistant haplotype of hydatidosis was significantly lower (p<0.01) than without this resistant haplotype. It showed that the genic haplotype MvaIbc-SacIIab-Hin1Iab of Ovar-DRB1 exon 2 was the resistant haplotype of hydatidosis in Kazakh sheep.

• 한국지반환경공학회 논문집
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• 제18권5호
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• pp.45-53
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• 2017

토압분리형 일체식 교대 교량은 일체식 교대 교량의 문제점을 개선하고자 Nam et al.(2016)에 의해 개발되었다. 본 연구에서는 IPM Bridge의 파일벤트의 돌출높이(H), 근입심도(L) 및 지반의 조건에 대한 매개변수 특성을 검토하기 위해 p-y 해석을 수행하였다. 그 결과, IPM Bridge의 파일벤트 두부는 상부구조와 일체화되어 최대 휨모멘트가 발생되었다. 해석에 사용된 지반조건에 따르면, 지중의 사질토와 풍화토의 경계면에서 최대 전단력이 발생되었다. 파일벤트의 최대 부재력과 비지지길이는 돌출높이와 근입심도의 비(L/H)가 1.0일 때 수렴되었으며, 파일벤트의 돌출높이보다 근입심도가 작을 경우에는 부재력이 과다하게 발생된다. p-y 해석 결과, 횡 방향 변위는 파일벤트의 근입깊이가 커질수록 뚜렷한 변곡점을 나타내었으며, 근입깊이가 작아질수록 완만한 곡선이 되었다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2007년도 추계종합학술대회
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• pp.819-821
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• 2007

The explosive growth of the Internet brought serious problems to the Internet routing infrastructure. Especially scaling problems is recognized more seriously. The ever increasing user population, as well as multiple other factors including multi-homing, traffic engineering, and policy routing, have been driving the growth of Default Free Zone (DFZ) routing table size at an alarming rate. While it has been long recognized that the existing routing architecture may have serious scalability problems, effective solutions have yet to be identified, developed, and deployed. Recently, several attempts for finding the concrete problems are made. Especially the report of the routing and addressing workshop which the IAB (Internet Architecture Board) held on 2006 is described the problems of the current internet in detail. This document describes those problems and introduces the related activity to solve the problems.

• 조명전기설비학회논문지
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• 제15권6호
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• pp.20-26
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• 2001

본 논문에서는 터널의 내공변위를 측정하고 측정된 데이터를 효율적으로 관리하는 계측 시스템을 설계하였다. 계측 시스템은 마이크로콘트롤러로와 포텐시오메터형 변위센서로 구성되는 Intelligent Sensing Head와 계측 시스템을 운용하고 측정된 데이터를 관리하는 호스트 컴퓨터로 구성된다. Intelligent Sensing Mead와 호스트 컴퓨터는 다중노드 통신방식에 의하여 연결되며 다중노드 네트워크의 안정된 동작을 위하여 Daisy-Chain 형태로 네트워크를 구성하였고 Fail-Safe 회로를 설계하였으며 Modbus 프로토콜을 사용하여 시스템의 범용성을 높였다. 호스트 컴퓨터는 종합관리 소프트웨어에 의하여 다양한 측정조건을 선택할 수 있으며 데이터베이스를 이용하여 측정된 데이터를 관리한다. 설계된 시스템은 터널에 설치되어 효용성을 확인하였다.

• 한국동물위생학회지
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• 제40권1호
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• pp.27-33
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• 2017

Salmonella enterica subsp. enterica is a common microbial flora in pet turtles, which could opportunistically become pathogenic to human. Their possession of aminoglycoside resistance genes has important significance both in humans and animal medicine. In this study, twenty-one Salmonella enterica subsp. enterica were isolated from thirty-five individual turtles purchased from pet shops and online markets in Korea. In order to characterize the aminoglycoside susceptibility patterns, antimicrobial susceptibility tests were performed against gentamicin, amikacin and kanamycin of aminoglycoside antimicrobial group. Each of the isolates showed susceptibility to all tested aminoglycosides in disk diffusion and minimum inhibitory concentration (MIC) tests. PCR assay was carried out to determine aminoglycoside resistance genes, integron and integron mediated aminoglycoside genes. None of the isolates showed aac(3)-IIa, aac-(6')-Ib, armA, aphAI-IAB aminoglycoside resistance genes. Only, five isolates (24%) harbored class 1 integron related IntI1 integrase gene. The results suggest that Salmonella enterica subsp. enterica strains isolated from pet turtles are less resistance to aminoglycosides and don't harbor any aminoglycosides resistance genes.

• 한국항해항만학회지
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• 제39권2호
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• pp.115-123
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• 2015

This study focused on the alternative to estimate the demand of employment in Kenya logistics. First of all, it investigated the importance and necessity of search about the present circumstance of the country's industry. Next, it reviewed respectively the concept and limitation of several previous models for employment, including Bureau of Labor Statistics, USA; ROA, Netherlands; IER (Institute for Employment Research), UK; and IAB, Germany. In regard to the demand forecasting of employers in logistics, it could anticipate more realistically the future demand by the time-lag approach. According to the findings, if value of output record 733,080 KSH million in 2015 and 970,640 in 2020, compared to 655,222 in 2013, demand on wage employment in logistics industry would be reached up to 95,860 in 2015 and 104,329 in 2020, compared to about 89,600 in 2012. To conclude, this study showed the more rational numbers about the demand forecasting of employment than the previous researches and displayed the systematic approach to estimate industry manpower in logistics.

• 인터넷정보학회지
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• 제14권3호
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• pp.5-20
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• 2013

ICANN has been governing the Domain Name System(DNS) "technically" since 1998. The architecture is called Internet Governance, and it brings about many different discourses; "What does that govern?", "Who delegate its role to ICANN?"," How could the regime ensure fairness?" etc. This article will analyze on Internet Governance by applying the government approach of Foucault, and try to compare two parts, the 'core' and the 'edge' of Internet Governance for method. Whereas the 'core' of it refers the site that be governed by the formal contract directly, the 'edge' as the rest of it means informal friendly relations with ICANN. The 'core' rule was stemmed from technological community such as IAB or IETF historically. They had invented new world and its population to integrate the technical order as protocol and the semiotic order as language, that be based on new government mode. On the other hand, ".KR" domain, one of the 'edges', has been evolved into more heterogeneous system, through contest and conflict between traditional state and Internet Governance. The governed object of ".KR" domain is situated in the crossing of each other the 'protocol user', the 'language-semiotic user' and the' geographical resident'. Here the 'geographical resident' rule was weird for DNS, so that shows the internal lack of Internet Governance. It needs to move to the concept of 'Hangeul(Korean-language) user' rather than the 'geographical resident'.

• Steel and Composite Structures
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• 제34권1호
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• pp.35-51
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• 2020

Integral abutment bridges (IABs) are those bridges without expansion joints. A single row of steel H-piles (SHPs) is commonly used at the thin and stub abutments of IABs to form a flexible support system at the bridge ends to accommodate thermal-induced displacement of the bridge. Consequently, as the IAB expands and contracts due to temperature variations, the SHPs supporting the abutments are subjected to cyclic lateral (longitudinal) displacements, which may eventually lead to low-cycle fatigue (LCF) failure of the piles. In this paper, the potential of using finite element (FE) modeling techniques to estimate the LCF life of SHPs commonly used in IABs is investigated. For this purpose, first, experimental tests are conducted on several SHP specimens to determine their LCF life under thermal-induced cyclic flexural strains. In the experimental tests, the specimens are subjected to longitudinal displacements (or flexural strain cycles) with various amplitudes in the absence and presence of a typical axial load. Next, nonlinear FE models of the tested SHP specimens are developed using the computer program ANSYS to investigate the possibility of using such numerical models to predict the LCF life of SHPs commonly used in IABs. The comparison of FE analysis results with the experimental test results revealed that the FE analysis results are in close agreement with the experimental test results. Thus, FE modeling techniques similar to that used in this research study may be used to predict the LCF life of SHP commonly used in IABs.

• Steel and Composite Structures
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• 제26권2호
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• pp.227-239
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• 2018

Integral abutment bridges (IABs) have no joint across the length of bridge and are therefore also known as jointless bridges. IABs have many advantages, such as structural integrity, efficiency, and stability. More importantly, IABs have proven to be have both low maintenance and construction costs. However, due to the restraints at both ends of the girder due to the absence of a gap (joint), special design considerations are required. For example, while replacing the deck slabs to extend the service life of the IAB, the buckling strength of the steel girder without a deck slab could be much smaller than the case with deck slab in place. With no deck slab, the addition of thermal expansion in the steel girders generates passive earth pressure from the abutment and if the applied axial force is greater than the buckling strength of the steel girders, buckling failure can occur. In this study, numerical simulations were performed to estimate the buckling strength of typical steel girders in IABs. The effects of girder length, the width of flange and thickness of flange, imperfection due to fabrication and construction errors on the buckling strengths of multiple and single girders in IABs are studied. The effect of girder spacing, span length ratio (for a three span girder) and self-weight effects on the buckling strength are also studied. For estimation of the reaction force of the abutment generated by the passive earth pressure of the soil, BA 42/96 (2003), PennDOT DM4 (2015) and the LTI proposed equations (2009) were used and the results obtained are compared with the buckling strength of the steel girders. Using the selected design equations and the results obtained from the numerical analysis, equations for preventing the buckling failure of steel girders during deck replacement for maintenance are presented.

• 한국임상약학회지
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• 제13권1호
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• pp.13-17
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• 2003

This study was carried out to compare the bioavailability of $Ceclex^{(R)}$ SR TAB (test drug, cefaclor 375 mg/Tablet) with that of Ceclor $MR^{(R)}$ SR IAB (reference drug) and to estimate the pharmacokinetic parameters of cefaclor in healthy Korean volunteers. The bioavailability was examined on 24 healthy volunteers who received a single dose (375 mg) of each drug in the fasting state in a randomized balanced 2-way crossover design. After dosing, blood samples were collected for a period of 7 hours. Plasma concentrations of cefaclor were determined using HPLC with UV detection. The pharmacokinetic parameters $(AUC_{0-7h},\;C_{max},\;T_{max},\;AUC_{inf},\;K_e,\;t_{1/2},\;V_d/F,\;and\;CL/F)$ were calculated with non-compartmental pharmacokinetic analysis. The ANOVA test was utilized for the statistical analysis of the $T_{max}$, log-transformed $AUC_{0-7h$}$, log-transformed $C_{max},\;t_{1/2},\;V_d/F$, and $CL/F$. The ratios of geometric means of $AUC_{0-7h}\;and\;C_{max}$ between test drug End reference drug were $95.67\%\;(8.55\;vs\;8.18{\mu}g{\cdot}hr/ml)\;and\;103.86\%\;(2.85\;vs\;2.96{\mu}g/ml)$, respectively. The $T_{max}$ of test drug and reference drug was $2.56\pm0.15\;and\;2.23\pm0.13\;hrs,\;respectively.\;The\;90\%$ confidence intervals of mean difference of logarithmic transformed $AUC_{0-7h}\;and\;C_{max}$ were log0.90-log1.04 and log0.91-log1.13, respectively. It shows that the bioavailability of test drug is equivalent with that of reference drug.