• Title/Summary/Keyword: I-max

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A Study on the Spatial Indexing Scheme in Geographic Information System (지리정보시스템에서 공간 색인기법에 관한 연구)

  • 황병연
    • Spatial Information Research
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    • v.6 no.2
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    • pp.125-132
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    • 1998
  • The I/O performance for spatial queries is extremely important since the handling of huge amount of multidimensional data is required in spatial databases for geographic information systems. Therefore, we describe representative spatial access methods handling complex spatial objects, z-transform B tree, KDB tree, R tree, MAX tree, to increase I/O performance. In addition, we measure the performance of spatial indexing schemes by testing against various realistic data and query sets. Results from the benchmark test indicates that MAX outperforms other indexing schemes on insertion, range query, spatial join. MAX tree is expected to use as index scheme organizing storage system of GIS in the future.

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Contrast Sensitivity as a function of spatial frequency by using polarization (편광을 이용한 눈의 공간주파수-대비민감도 함수 측정기구 설계)

  • Kim, Young-Geun
    • Journal of Korean Ophthalmic Optics Society
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    • v.5 no.1
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    • pp.43-48
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    • 2000
  • It was to adjust the luminance of light by the rotation angle of the polarizes and analyzer. The luminance value Lmax, Lmin of Contrast Sensitivity could be obtained from the rotation angle ${\theta}_m$ of the average luminance($L_m$), the rotation angle(${\theta}_{max}$, ${\theta}_{min}$) of the maximum and the minimum's amplitude. $$L_{max}=I(0)e^{-2at}{\cdot}cos^2{\theta}_m(1+C_s^{-1})$$ $$L_{min}=I(0)e^{-2at}{\cdot}cos^2{\theta}_m(1-C_s^{-1})$$ We obtained the rotation angle(${\theta}_{max}$, ${\theta}_{min}$) of the polarizes and analyzer from the rotation angle ${\theta}_m$ of the average luminance($L_m$) and the Contrast Sensitivity($C_s$). $${\theta}_{max}=cos^{-1}[cos{\theta}_m{\cdot}(1+C_s^{-1})^{1/2}]$$ $${\theta}_{min}=cos^{-1}[cos{\theta}_m{\cdot}(1-C_s^{-1})^{1/2}]$$.

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Bioequivalence Evaluation of the Cisapride Formulation Produced by Dong Wha Pharmaceutical Co. (동화약품 시사프리드제제의 생물학적 동등성 평가)

  • 윤광희;박진영;박선주;조은희;유제만;김경식;정석재;이민화;심창구
    • Biomolecules & Therapeutics
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    • v.7 no.1
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    • pp.59-65
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    • 1999
  • A bioequivalence study of the Dong Wha Cisapril tablets(Dong Wha Pharm. Ind. Co., Ltd.) to the Prepulsid tablets(Janssen Korea Ltd.), formulations of cisapride, was conducted. Twenty four healthy Korean male subjects received each formulation at the dose of 5 mg as cisapride in a 2$\times$2 crossover study. There was a 1-week washout period between the doses. Plasma concentrations of cisapride were monitored by an LC/MS method for over a period of 36 h after each administration. AUC(area under the plasma concentration- time curve from time zero to infinity) was calculated by the linear trapezoidal and extrapolation method. $C_{max}$ (maximum plasma drug concentration) and $T_{max}$ (time to reach $C_{max}$) were compiled from the plasma drug concentration-time data. Analysis of variance (ANOVA) revealed that there are no differences in AUC, $C_{max}$ and $T_{max}$ between the formulations. The apparent differences between the formulations in these parameters were all far less than 20% (i.e., 6.8, -6.6 and 1.8% for AUC, $C_{max}$ and $T_{max}$, respectively). Minimum detectable differences(%) at $\alpha$=0.05 and 1-$\beta$=0.8 were all less than 20% in these parameters between the formulations (i.e., 16.5, 11.4 and 16.4% for AUC, $C_{max}$ and $T_{max}$, respectively). The 90% confidence intervals for these parameters were also within 20% (i.e., -2.9~ 16.4, -13.2~0.1 and -7.8~ 11.4% for AUC, $C_{max}$ and $T_{max}$, respectively). These results satisfy the bioequivalence criteria of the Korea Food and Drug Administration (KFDA) guidelines (No. 98-51). Therefore, these results indicate that the two formulations of cisapride are bioequivalent and, thus, may be prescribed interchangeably.hangeably.y.hangeably.

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Comparison of voice range profiles of modal and falsetto register in dysphonic and non-dysphonic adult women (음성장애 성인 여성과 정상음성 성인 여성 간 진성구와 가성구의 음성범위프로파일 비교)

  • Jaeock Kim;Seung Jin Lee
    • Phonetics and Speech Sciences
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    • v.14 no.4
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    • pp.67-75
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    • 2022
  • This study compared voice range profiles (VRPs) of modal and falsetto register in 53 dysphonic and 53 non-dysphonic adult women with gliding vowel /a/'. The results shows that maximum fundamental frequency (F0MAX), maximum intensity (IMAX), F0 range (F0RANGE), and intensity range (IRANGE) are lower in the dysphonic group than in the non-dysphonic group. F0MAX and F0RANGE are significantly higher in falsetto register than modal register in both groups. IMAX and IRANGE are significantly higher in falsetto register in the non-dysphonic group, but those are not different between two registers in the dysphonic group. There was no statistically significant difference in minimum F0 (F0MIN) and minimum intensity (IMIN) between the two groups. Modal-falsetto register transition occurred at 378.86 Hz (F4#) in the dysphonic group and 557.79 Hz (C5#) in the non-dysphonic group, which was significantly lower in the dysphonic group. It can be seen that both modal and falsetto registers in dysphonic adult women are reduced compared to non-dysphoinc adult women, indicating that the vocal folds of dysphonic adult women are not easy to vibrate in high pitches. The results of this study would be the basic data for understanding the acoustic features of voice disorders.

A Study on the Initial Maximum Value of Heat Flux, $q_{max}$ of Wool Fabrics (Part I) - The correlation between $q_{max}$ and thermal conductivity, thermal transmittance, surface air cavity of wool fabrics - (양모 복지의 초기열류속최대치($q_{max}$)에 관한 연구( I ) -열전도도, 열통과성, 표면기공도와의 상관성을 중심으로-)

  • Choi Suk Chul;Jung Jin Soun;Chun Tae il
    • Journal of the Korean Society of Clothing and Textiles
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    • v.15 no.4 s.40
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    • pp.367-372
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    • 1991
  • In this study, we discussed about the factors effected upon the initial maximum value of heat flux ($q_{max}$). Thermal conductivity, thermal transmittance and surface air cavity of wool fabrics were examind and their correlation to the $q_{max}$ was studied. The factors were examined which had an effect upon the $q_{max}$ of an objective measure of warm/cool feeling. It was simulated by Thermo-Labo apparatures. We selected twenty sorts of pure wool woven fabrics for men's fall -winter cloth (all Wool). The conclusions are as follows; 1. There was not a certain correlation between the $q_{max}$ and the thermal conductivity of wool fabric. 2. When the fabrics touched on the copper plates, the thickness of wool fabric had a negative correlation to the $q_{max}$. The thermal transmittance had a positive correlation. Both of them had a good correlation to the $q_{max}$. 3. As a major factor, the thickness of fabric effected on the $q_{max}$.

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Measurement of Phosphorus Buffering Power in Various Soils using Desorption Isotherm (탈착 등온식을 이용한 토양 중 인산 완충력 측정)

  • Lee, Jin-Ho;Doolittle, James J.
    • Korean Journal of Soil Science and Fertilizer
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    • v.37 no.4
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    • pp.220-227
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    • 2004
  • Phosphorus desorption study is essential to understanding P behavior in agricultural and environmental soils because phosphorus is considered as two different aspects, a plant nutrient versus an environmental contaminant. This study was conducted to determine soil P buffering power related to P desorption quantity intensity (Q/I) parameters, $Q_{max}$(an index of P release capacity) and $l_0$(an index of the intensity factor), and to investigate the characteristics of relationship between the P desorption Q/I parameters and the soil properties. Soil samples were prepared with treatments of 0 and $100mg\;P\;kg^{-1}$ applied as $KH_2PO_4$ solution. The P desorption Q/I curves were obtained by a procedure using anion exchange resin beads and described by an empirical equation ($Q=aI^{-1}+bln(I+1)+c$). The P desorption Q/I curves for the high available P (${\g}20mg\;kg^{-1}$ of Olsen P) soils were characteristic concave trends with or without soil P enrichment, whereas for the low available P (${\lt}20mg\;kg^{-1}$ of Olsen P) soils, the anticipated Q/I concave curves could not be obtained without a proper amount of P addition. When the soils were enriched in phosphates, the values of desorbed solid phase labile P and solution P, such as $Q_{max}$ and $I_0$ respectively, were increased, but the ratio of $Q_{max}$ versus $I_0$ was decreased. Thus, the slope of desorption Q/I curve represented as phosphorus buffering power, $|BP_0|$, is decreased. The $|BP_0|$ values of the high available P soils ranged between 48 and $61L\;kg^{-1}$ in the P untreated samples and between 18 and $44L\;kg^{-1}$ in the P enriched samples. Overall $|BP_0|$ values of both low and high available P soils treated with $l00mg\;P\;kg^{-1}$ ranged between 14 and $79L\;kg^{-1}$. The $Q_{max}$, values ranged between 71.4 and $173.1mg\;P\;kg^{-1}$, and the lo values ranged between 0.98 and $3.82mg\;P\;L^{-1}$ in the P enriched soils. The $Q_{max}$ and $I_0$ values that control the P buffering power may be not specifically related to a specific soil property, but those values were complicatedly related to soil pH, clay content, soil organic matter content, and lime. Also, phosphorus release activity, however, markedly depended on the desorbability of the applied P as well as the native labile P.

Filtration Rates of Juvenile Purple Clam, Saxidomus purpuratus (Sowerby) Feeding on Red Tide Dinoflagellates

  • Lee, Chang-Hoon;Moon, Seong-Dae;Sung, Chan-Gyoung
    • The Korean Journal of Malacology
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    • v.28 no.4
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    • pp.349-359
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    • 2012
  • The purpose of this study is to compare the clearance rate (CR) and intake rate (IR) of juvenile purple clam, Saxidomus purpuratus when feeding on different unialgal diet of red tide dinoflagellates (RTDs), and to know what is the most important cell characteristic of RTDs to cause the differences in feeding parameters. Experiments were performed to measure the CR and IR of juvenile S. purpuratus as a function of algal concentration when food was either the standard food, Isochrysis galbana or one of 9 RTDs. Patterns of CR with increasing algal concentration were similar among different RTDs. The highest $C_{max}$ was observed when S. purpuratus was feeding on A. affine, while the lowest on C. polykrikoides. The patterns of IR with increasing algal concentration were also similar among different RTDs. However, there were great differences in the maximum value of IR ($I_{max}$) among different RTDs. The highest $I_{max}$ was observed when S. purpuratus was feeding on A. carterae, while the lowest on G. catenatum. Some RTDs similar in size showed different $C_{max}$. Other RTDs different in size showed similar $I_{max}$. Life form of each RTD affected significantly the $I_{max}$, which was higher for single-celled RTDs than chain-forming RTDs. There were no significant differences in feeding parameters between toxic and nontoxic RTDs. Moreover, a toxic dinoflagellate, A. carterae recorded the highest $I_{max}$ among RTDs. The most important characteristic of RTD as a factor affecting the feeding rate of S. purpuratus was life form, not size or toxicity of RTD species.

Variation of Leucine Aminoeptidase Isozyme in Korean Land Races and Wild Soybeans (한국 재래 및 야생종 콩의 Leucine Aminopeptidase 변이)

  • 박경숙;윤문섭
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.42 no.2
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    • pp.129-133
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    • 1997
  • A total 943 accession of soybeans (G. max) and 50 wild soybeans (G. soja) were examined for leucine aminopeptidase (LAP) isozyme variation by 5% polyacrylamide gel electrophoresis(PAGE) and isoelectric focusing(IEF) of pH 4~6.5. The Lap1*b by PAGE was the most common phenotype in both G. max and G. soja. The frequency of Lap1*b allele was observed to be higher in G. max(1.00) than in G. soja(0.96) of Korea. This result shows that G. max is fixed for Lapl*b allele at the Lap1 locus. LAP isozyme band type I and II were found using IEF of pH 4~6.5 in G. max and G. soja of Korea. Type I was observed from 92.8% in G. max and 92.0% in G. soja, and type II was discovered in 7.2% G. max and 8.0% G. soja. This result suggested the possibility to be found more various band types.

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Bioequivalence Study of Acetyl-L-Carnitine Tablets (아세틸-엘-카르니틴 정제의 생물학적 동등성 평가)

  • 박경미;이미경;신지영;임수정;임윤영;김종국;우종수
    • Biomolecules & Therapeutics
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    • v.9 no.4
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    • pp.285-290
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    • 2001
  • Bioequivalence of two acetyl-1-carnitine tablets, test product (Carnitile tablet: Hanmi Pharm. Co., Ltd.) and reference product (Nicetil $e^{R}$ tablet: Dong-A Pharm. Co., Ltd.), was evaluated according to the guide- lines of Korea Food and Drug Administration (KFDA). Twenty-six healthy volunteers were divided randomly into two groups and administered the drug orally at the dose of 500 mg as acetyl-1-carnitine in a 2$\times$2 crossover study. Blood samples were taken at predetermined time intervals for 12 hours and the plasma concentration of acetyl-1-carnitine was determined using HPLC by derivatization with p-bromophenacyl bromide. The pearmacokinetic parameters (AU $C_{0-}$12h/ $C_{max}$ and $T_{max}$) were calculated and ANOVA was utilized for the statistical analysis of parameters. The apparent differences of these parameters between two drugs were less than 20% (i.e., 1.26,-5.08 and 8.59% for AU $C_{0-}$12h/ $C_{max}$ and $T_{max}$, respectively). The powers (1-$\beta$) for AU $C_{0-}$12h/ $C_{max}$ and $T_{max}$, and Tmax were over 0.9. Minimal detectable difference ($\Delta$) at $\alpha$=0.05, 1-$\beta$=0.8 were less than 20% (i.e.,7.31, 14.88 and 11.77% for AU $C_{0-}$12h/ $C_{max}$ and $T_{max}$, respectively). The confidence intervals ($\delta$) for these parameters were also within $\pm$ 20% (i.e.,-3.03$\leq$$\delta$$\leq$5.54, -13.80$\leq$$\delta$$\leq$3.64 and 1.69$\leq$$\delta$$\leq$15.48 for AU $C_{0-}$12h/ $C_{max}$ and $T_{max}$, respectively). These results satisfied the criteria of KFDA guideline for bioequivalence, indicating Carnitile bioequivalent to Nicetil $e^{R}$ .TEX>$^{R}$ .> R/ . R/ .

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On Detecting the Best Treatment

  • Kim, Woo-Chul
    • Journal of the Korean Statistical Society
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    • v.17 no.2
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    • pp.81-92
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    • 1988
  • We observe independent random variable $Y_i \sim N(\theta_i,1), i=1,2,\cdots,k$, and we are interested in detecting the treatment with the largest $\theta_i$. We consider a procedure which infers $\theta_{(k)} \geq max\theta_i (i\neq(k))$ whenever $Y_{(k)} \geq maxY_i+C (i\neq(k))$. The maximum probability of a false inference is found, and it is shown that the inference can be made with the two-sample one-sided critical value for the usual error levels. The result also holds in the case of common unknown variance.

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