• The Journal of Korean Society for Radiation Therapy
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• v.15 no.1
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• pp.19-27
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• 2003

I. Purpose In special cases of Total Body Irradiation(TBI), Half Body Irradiation(HBI), Non-Hodgkin's lymphoma, E-Wing's sarcoma, lymphosarcoma and neuroblastoma a large field can be used clinically. The dose distribution of a large field can use the measurement result which gets from dose distribution of a small field (standard SSD 100cm, size of field under $40{\times}40cm2$) in the substitution which always measures in practice and it will be able to calibrate. With only the method of simple calculation, it is difficult to know the dose and its uniformity of actual body region by various factor of scatter radiation. II. Method & Materials In this study, using Multidata Water Phantom from standard SSD 100cm according to the size change of field, it measures the basic parameter (PDD,TMR,Output,Sc,Sp) From SSD 180cm (phantom is to the bottom vertically) according to increasing of a field, it measures a basic parameter. From SSD 350cm (phantom is to the surface of a wall, using small water phantom. which includes mylar capable of horizontal beam's measurement) it measured with the same method and compared with each other. III. Results & Conclusion In comparison with the standard dose data, parameter which measures between SSD 180cm and 350cm, it turned out there was little difference. The error range is not up to extent of the experimental error. In order to get the accurate data, it dose measures from anthropomorphous phantom or for this objective the dose measurement which is the possibility of getting the absolute value which uses the unlimited phantom that is devised especially is demanded. Additionally, it needs to consider ionization chamber use of small volume and stem effect of cable by a large field.

• Radiation Oncology Journal
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• v.28 no.2
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• pp.79-84
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• 2010

Purpose: We retrospectively analyzed the long-term results of radical surgery and intraoperative radiation therapy (IORT) in patients with stomach cancer. Materials and Methods: From 1988 to 1994, 51 patients were treated with curative surgery and IORT. Postoperative external beam radiotherapy (EBRT) was administered to 30 patients, while adjuvant chemotherapy was administered to 35 patients. A dose of 15 Gy was irradiated with a 9 MeV electron beam as the IORT and a median dose of EBRT was 43.2 Gy (range, 7.2 to 45 Gy). The follow-up period ranged from 1~254 months, with a median follow-up period of 64 months. Results: The median age of all the patients was 58 years (range, 30 to 71 years). The distribution of pathologic stage (American Joint Committee on Cancer [AJCC] 2002 tumor-note-metastasis [TNM]) was as follows: 13 stage I (25.5%), 10 stage II (19.6%), 25 stage III (49.0%), and 3 stage IV (5.9%). Distant metastases occurred in 11 patients (10 in the peritoneum and 1 in bone), including one patient with concurrent local recurrence (anastomosis site). The 5-year locoregional control, disease free survival and overall survival rates were 94.7%, 66.5%, and 51.7%, respectively. For the multivariate analysis, age, TNM stage, and EBRT were significant prognostic factors for overall survival, and only TNM stage for disease free survival. Conclusion: We could have achieved a high loco-regional control rate in patients with locally advanced stomach cancer by adding IORT to radical surgery. However, the benefit of IORT on survival remains to be elucidated.

• Journal of Radiation Protection and Research
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• v.35 no.2
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• pp.85-90
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• 2010

In the present work, peak relative efficiency for the energy was obtained and response function was worked out. This study was carried out using the high resolution high efficiency HPGe detector(diameter 78.7 mm, length 86.5 mm) and NaI(Tl) detector for anti-compton. The anti-coincidence of the signals from the two detectors could be used to lessen the Compton effect signal; thus, the $\gamma$-ray energy resolution could be improved. The $\gamma$-ray spectrum was measured at $55^{\circ}$ to the direction of the incident proton beam. Reaction spectrum was obtained from the $^{23}Na$(p, $\gamma$)$^{24}Mg$ reaction at $E_p$ = 1424 keV and $^{27}Al$(p, $\gamma$)$^{28}Si$ reaction at $E_p$ = 992 keV. To accelerate the incident proton which creates the (p, $\gamma$) capture reaction, the 3 MeV Pelletron accelerator at the Tokyo Institute of Technology was used. Response function was worked out by a noble technique. We worked out a response function from 1.2 to 9.4 MeV at intervals of 0.75 MeV.

• Korean Journal of Optics and Photonics
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• v.7 no.3
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• pp.251-259
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• 1996

Two-Photon Fluorescence (TPF) experiment measures temporal width of an amplified short laser pulse which has passed through a four-pass Nd: glass amplifier, after selecting a single pulse from pulse train Q-switched and mode-locked(QSML) in Nd:YLF master oscillator. Determination of pulsewidth and pulseshape was also made with detection of autocorrelation trace of CW mode-locked pulse train by using noncollinear type I Second Harmonic Generation (SHG) method. The observed TPF track showed various patterns, depending on pulse-selecting position in QSML pulse train. That is, autocorrelation of a pulse extracted at front of the train displayed smooth pulse shape, while one from the trailing part of the train created many sharp spikes and substructure in the pulse. By TPF method, pulsewidth was measured to be 44.4 ps with contrast ratio of 2.86 which enabled us to find out energy fraction of a pulse to total energy, (sum of pulse and background); we obtain the value of 0.62. Pulsewidth of 46.6ps was also acquired in another SHG experiment with the help of only mode-locked pulse train. On the other hand, we confirmed that shape of the pulse is close to $sech^2$ one as a result of fitting the SHG autocorrelation signal with various functions. With simulation using this $sech^2$ type of pulse, pulsewidth reduction of the beam, having passed through four-pass amplifier, was also verified.

• Journal of the Korea Concrete Institute
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• v.13 no.5
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• pp.457-465
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• 2001

Shrinkage strains of concrete slab in multi-story building are restrained by structural members such as columns or walls, then can induce cracks due to excessive shrinkage stress over tensile strength of member. In this study, a shrinkage stress analysis method of concrete slab in multi-story building considering not only material properties such as shrinkage, creep and reinforcement effect but also construction sequence is proposed. Tensile stresses of slab due to shrinkage are calculated by converting shrinkage strains into equivalent temperature gradients, creep that can release shrinkage stress can be considered by replacing the modulus of elasticity of concrete, Ec , to the effective secant modulus of elasticity of concrete, E$\_$eff/ Reinforcements are also considered by modeling them as equivalent beam elements in FEM program. Results of step by step analysis reflecting construction sequence summed up to calculate stresses of the whole building considering that shrinkage stresses of the building come from the difference of shrinkage between i-th floor and (i-1)-th floor, named as effecitive shrinkage, and it can be varied by construction sequence. The results of 10-story example building show that shrinkage stresses of lower floors are greater than those of upper floors, that is, stresses of lower floors(1∼2FI.) exceed modulus of rupture of concrete, but stress ratios of higher floors are in the range of 27.9∼92.8%.

• Journal of Korea Water Resources Association
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• v.38 no.12 s.161
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• pp.1039-1049
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• 2005

The objective of this study is to produce optimal radar-derived rainfall for hydrologic utilization. The ground clutter and beam blockage effects from Mt. Kwanak station (E.L 608m) are removed from radar reflectivities by POD analysis. The reflectivities are used to produce radar rainfall data in the form of rain rates (mm/h) by the application of the Marshall-Palmer reflectivity versus rainfall relationship. However, these radar-derived rainfall are underestimated in temporal and spatial scale compared with observed one, so it is necessary to hire a correction scheme based on the gauge-to-radar (G/R) statistical adjustment technique. The selected watershed for studying the real-time correction of radar-rainfall estimation is the Soyang dam site, which is located approximately 100km east of Kwanak radar station. The results indicate that adjusted radar rainfall with the gauge measurement have reasonal G/R ratio ranged on 0.95-1.32 and less uncertainty with that mean standard deviation of G/R ratio are decreased by $9-28\%$. Mean areal precipitation from adjusted radar rainfall are well agreed to the observed one on the Soyang River watershed. It is concluded that the real-time bias adjustment scheme is useful to estimate accurate basin-based radar rainfall for hydrologic application.

• 한국방재학회:학술대회논문집
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• 2011.02a
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• pp.155-155
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• 2011

일반적으로 I형 보에 횡하중이 작용하는 경우, 횡 변위와 함께 회전을 동반하는 횡-비틀림 좌굴(Lateral-Torsional Buckling)이 발생하게 된다. 이러한 I형 보의 탄성 및 비탄성 횡-비틀림 좌굴에 대한 해석적 이론적 연구는 이미 많은 연구자들에 의해 수행되었다(Timoshenko 등, 1961; Galambos, 1963; Lindner, 1974; Trahair, 1993). I형 보의 비지지 길이 내 하중이 작용할 때 모멘트 구배계수(Cb)는 하중이 부재 단면에 작용하는 위치에 따라 달라지게 되는데 이를 하중고 효과(Load Height Effects)라고 한다. 탄성 영역 내 비지지길이가 존재하는 I형 보의 하중고 효과를 고려한 모멘트 구배계수 제안식은 Nethercot & Rockey(1971)에 의해 연구된 바 있다. 또한 Helwig 등(1997)은 Nethercot & Rockey(1971)의 제안식을 간략화 하여 탄성 영역 내 비지지길이가 존재하는 I형 보의 하중고 효과를 고려한 모멘트 구배계수식을 제안하였다. 그러나 현재까지 진행 된 하중고 효과에 대한 연구는 탄성 영역 내 비지지 길이가 존재하는 I형 보에 대한 제안식이며 현재까지 비탄성 영역 내 비지지 길이를 갖는 I형 보의 하중고 효과에 대한 연구는 진행된 바 없다. 본 연구는 비탄성 영역 내 비지지 길이가 존재하는 I형 보의 하중고 효과를 고려한 비탄성 횡-비틀림 좌굴강도에 대한 연구를 수행하였다. 하중조건으로는 집중하중 과 등분포 하중을 적용시켰으며, 비선형 횡-비틀림 좌굴 해석을 위해 잔류응력 및 초기변형을 고려하였다. Pi와 Trahair(1995)이 고려한 단순직선분포를 잔류응력으로 가정하였으며, 국내 I형강 표준 치수 허용치(현대제철, 2006)에 근거하여 부재 길이의 0.1%를 초기 최대 횡 변위로 적용하여 초기제작오차로 고려하였다. 유한요소해석결과를 바탕으로 Nethercot & Rockey(1971)와 Helwig 등(1997)의 연구내용을 바탕으로 범용구조해석 프로그램(ABAQUS, 2007)을 이용하여 비탄성 영역 내 존재하는 I형보의 횡-비틀림 좌굴강도를 산정하였다. 유한요소해석결과를 바탕으로 Nethercot & Rockey(1971)및 Helwig 등(1997)의 모멘트구배계수 제안식과 비교 분석 하였고 회기분석프로그램 MINITAB(2006)을 이용하여 비탄성 영역 내 비지지길이가 존재하는 I형보의 하중고 효과를 고려한 모멘트구배계수식을 개발 제안하였다. 본 연구에서 개발된 제안식은 경제적이고 합리적인 휨부재 강도평가에 적극 활용될 수 있으며, 비탄성 영역내 I형보의 횡-비틀림 좌굴강도 및 휨강도 연구에 널리 활용될 것이다.

• The Journal of Korean Society for Radiation Therapy
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• v.19 no.1
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• pp.43-49
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• 2007

Purpose: The aim of this study was the clinical implementation of IGRT using KV CBCT for setup correction in radiation therapy. Materials and Methods: We selected 9 patients (3 patient for each region; head, body, pelvis)and acquired 135 CBCT images with CLINAC iX (Varian medical system, USA). During the scan, the required time was measured. We analyzed the result in 3 direction; vertical, longitudinal, lateral. Results: The mean setup errors at the couch position of vertical, lateral, and longitudinal direction were 0.07, 0.12, and 0.1 cm in the head region, 0.3, 0.26, and 0.22 cm in the body region, 0.21, 0.18, and 0.15 cm in the pelvis region respectively. The mean time required for CBCT was $6{\sim}7$ minute. Conclusion: The CBCT on the LINAC provides the capacity for soft tissue imaging in the treatment position and real time monitoring during treatment delivery. With presented workflow, the setup correction within reasonable time for more accurate radiation therapy is possible. And it's image can be very useful for adaptive radiation therapy(ART) in the future with improved image quality.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.2 no.2
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• pp.123-131
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• 2016

Increasing clinical demand for carbon-11 labeled radiopharmaceuticals has triggered technological advances in fields of radiochemistry and automated modules. Even though carbon-11 has a short half-life ($t_{1/2}=20.4min$), the consecutive second production of carbon-11 labeled radiopharmaceutical in one $^{11}C$-synthetic module should be delayed at least over 4 h to avoid the high radiation exposure. We herein aimed to produce two different carbon-11 labeled radiopharmaceuticals ([$^{11}C$]PIB and [$^{11}C$]methionine) by sharing of [$^{11}C$]methylation source in one $^{11}C$-synthetic module. The synthesis of $^{11}C$-labeling reagents ($[^{11}C]CH_3I$ or $[^{11}C]CH_3OTf$) is fully automated using the commercial TRACERlab $FX_{C-pro}$ module and is readily adaptable to $^{11}C$-labeling reactor for [$^{11}C$]PIB as well as another $^{11}C$-labeling apparatus for [$^{11}C$]methionine via the three-way valve. After completing the [$^{11}C$]PIB production, the re-synthesized $[^{11}C]CH_3I$ was passed through the three-way valve connected the polyetheretherketone (PEEK) line and loaded into the C18 Sep-Pak cartridge including the methionine precursor. The labeled product [^${11}C$]methionine was purified by a simple cartridge separation and reformulated into saline. The radiochemical yield of [$^{11}C$]PIB and [$^{11}C$]methionine were $5.3{\pm}0.6%$ and $18.7{\pm}0.8%$ (n.d.c.), respectively, with over 97% of radiochemical purity. The specific activity of [$^{11}C$]PIB was over $110GBq/{\mu}mol$. Total production time of two radiopharmaceuticals needs about 2 h from $1^{st}$ beam irradiation including quality control tests. Final [$^{11}C$]PIB and [$^{11}C$]methionine were satisfied all quality control test standards.

• Journal of the Korea Concrete Institute
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• v.28 no.3
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• pp.257-265
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• 2016

The failure behavior of reinforced concrete beams is governed by the mechanical relationships between the shear span-to-effective depth ratio, flexural reinforcement ratio, load and support conditions, and material properties. In this study, two simple indeterminate strut-tie models which can reflect all characteristics of the failure behavior of reinforced concrete beams were proposed. The proposed models are effective for the beams with shear span-to-effective depth ratio of less than 3. For each model, a load distribution ratio, defined as the fraction of load transferred by a truss mechanism, is also proposed to help structural designers perform the rational design of the beams by using the strut-tie model approaches of current design codes. In the determination of the load distribution ratios, the effect of the primary design variables including shear span-to-effective depth ratio, flexural reinforcement ratio, and compressive strength of concrete was reflected through numerous material nonlinear analysis of the proposed indeterminate strut-tie models. In the companion paper, the validity of the proposed models and load distribution ratios was examined by applying them to the evaluation of the failure strength of 335 reinforced concrete beams tested to failure by others.