• Journal of Korean Academy of Nursing
• /
• v.15 no.3
• /
• pp.62-73
• /
• 1985

The problems of growth & development due to maladjustment are gradually increasing while need for the treatment of children's diseases is decreasing. The level of developmental deficiency or delay correlates with neonatal birth weight and also with gestational age, i.e. degrees of prematurity. There-fore, developmental defects and potential risk factors' are more Common in premature infants than in full term infants. The purpose of this study is to define the difference in the growth at developmental status between premature and full term infants, and to define the relation between the developmental status and the physical growth during the first 3 years' Data were collected from January 10, 1985 to April 6, 1985 at 3 hospitals including St. Mary's Hospital, and through home visiting. The subjects of this study consisted of 79 Premature infants (G.A. <37wks. & B.W. <2.5kg) and 94 full term infants (G.A.≥37 wks. & B.W.≥2.5kg). The study method used was a questionnaire, anthropometric assessment and DDST for normative data of growth & development. The collected data were analyzed using descriptive statistics, chi-square test and t-test. The results of the study were as follows: Hypothesis: 1 : That the prematures will differ from the full term infants in the physical growth status during the first 3 years was partially supported (p＜0.02) : The prematures reached up the full term infants in the physical growth status in the first 6 months. And, the first hypothesis was supported (P<0.01) : There are more cases which is below‘the Korean children's physical. growth standards’in prematures than in full term infants. Hypothesis 2 : That the prematures will differ from the full term infants in the developmental status during the first 3 years was supported (P< 0.001)；‘Normal’developmental status due to DDST was less in prematures than in full term infants. And, the second hypothesis was Partially supported (P<0.02) : The developmental status of the pre-matures was different from that of the full term infants within the first 3 months by analysis of passed items in DDST, Hypothesis 3 : That the prematures' developmental status will relate to their physical growth during the first 3 years was supported (P<0.001) : If the prematures' developmental status is in delayed status, then, their physical growth status is also in delayed status. This study shows that the prematures differed significantly from the full term infants in the growth at developmental status during their infancy. This means that the nurse can foster the growth & development of the prematures by supportive care during their infancy. Further longitudinal study is needed to verify these findings for the environmental factors.

• Journal of Korean Academy of Nursing
• /
• v.36 no.3
• /
• pp.532-541
• /
• 2006

Purpose: This study was conducted to verify the effects of an education program of restraints use on nurses' knowledge, attitude and nursing performance related to restraints use. Method: A quasi experimental study with a pre and post non-equivalent design was used. The subjects were nurses who met the selection criteria and worked in intensive care units of two university hospitals located at K-city, Gyeongbuk. Twenty nurses in A hospital were designated as the experimental group and 20 nurses in B hospital as the control group. Result: The first hypothesis which assumed that the experimental group would have higher scores of knowledge than the control group was supported(F=62.66, p=0.000). The second hypothesis which assumed that the experimental group would have lower scores of attitude toward using restraints than the control group was supported(F=23.77, p=0.000). The third hypothesis which assumed that the experimental group would have higher scores of nursing performance than the control group was supported(F=3.28, p=0.032). Conclusion: An education program for nurses' on the use of restraints needs to be introduced to decrease inappropriate use of restraints.

• Journal of Korean Academy of Nursing
• /
• v.4 no.2
• /
• pp.32-43
• /
• 1974

A steady increase in the aged population poses a great challenge to nurses with their diversities of health care needs, especially of psychological nature, such as an alienation problems among the aged. The purpose of this study is to examine the nature of alienation problems among the aged in urban areas to provide basic informations for a better understanding of aged people. In this study, the investigator has tried to identify causes of alienation in the aged, and to determine the extent of alienation in relation to sex, family structure, religion, economic status and participation in social activities. The survey was done during the period from the last part of August to the end of September 1973. After a day's training, 10 interviewers have interviewed 210 stratified random samples of people over the age of 65 residing in Seoul with the free-ended questionnaire prepared by the investigator. The result of the study was tested by Critical Ratio. Following Hypothesis have guides formulation of the study: I. The extent of alienation in old man would be higher than in old woman, II. The extent of alienation in the aged who live alone would be higher than those living with their family. III. The extent of alienation in the aged who have no spouse would be higher than who live with their spouse. IV. The extent of alienation in the people without religious beliefs would be higher than the people with religious biles. V. The extent of alienation in the aged would be higher in proportion to decreased level of their economic productivity. Ⅵ. The extent of alienation in the aged who do not participate in social activities would be higher than that of the aged who actively participate. The analytic results of the study are as fellows: 1. The extent of alienation in woman was revealed higher than that of man by showing significant difference at P〈0.01 level. (CR=3.66) Accordingly hypothesis I was denied. 2. The extent of alienation in the aged wile live alone was revealed higher than that of the aged who live with their family by showing a significant difference at P<0.01 level. (CR=7.31) So hypothesis II was supported. 3. The extent of alienation of the aged who have no spouse was revealed higher than that of the aged who live with their spouse at the significant level of P <0.01. CR=4.65) Accordingly hypothesis III was supported, 4. There was no significant difference in the extent of alienation between the people with and-without religion. Thus hypothesis IV was rejected. 5. The extent of alienation in the aged was found to be higher in proportion to decreased level of their economic ability. a. The aged with greatest income showed least alienation b. The aged with no income had a greater extent of alienation than the aged with minimal income by showing significant difference at P <0.01 level . (CR=4.82) c. The difference between the greatest income group and the minimal income group was. found to be less significant than the difference between minimal income group and the-people without income. Thus hypothesis V was positively supported. 6. The extent of alienation in the aged who do not participate in social activities was higher than that of the aged who actively participate. (P <0.01, CR=6.24) According1y hypothesis Ⅵ was supported.

• Journal of Microbiology and Biotechnology
• /
• v.30 no.5
• /
• pp.733-738
• /
• 2020

Glucose deprivation and hypoxia frequently occur in solid tumor cells, including pancreatic cancer cells. Glucose deprivation activates the unfolded protein response (UPR) and causes the up-regulation of glucose-regulated protein 78 (GRP78). Induction of GRP78 has been shown to protect cancer cells. Therefore, shutting down of GRP78 expression may be a novel strategy in anticancer drug development. Based on this understanding, a screening system established for anticancer agents that exhibit selective cytotoxicity on pancreatic cancer cells under glucose-deprived conditions. To test this hypothesis, the new compounds isolated, pancastatin A (PST-A) and B (PST-B), from Ponciri Fructus. PST-A and B were identified as glabretal triterpenoid moieties by electrospray ionization mass spectrometry and nuclear magnetic resonance spectroscopic methods. PST-A and B suppressed the accumulation of the UPR hallmark gene, GRP78, during glucose deprivation. Furthermore, PST-A and B showed selective cytotoxicity on PANC-1 pancreatic cancer cells under glucose deprivation. Interestingly, PST-A and B had no effect on these cells under normal growth conditions. Our results suggest that PST-A and B act as novel therapeutic agents to induce selective cell death in glucose-deprived pancreatic cancer cells.

• Korean Journal of Biological Psychiatry
• /
• v.3 no.2
• /
• pp.245-250
• /
• 1996

This research was performed to find out the changes of serotonin receptors in the platelet of alcoholics. Using $_{125}I-LSD$ as a radioligand. We obtained the following results. 1) In the comparison of patients vs controls, $B_{max}$ of the former was significantly higher than that of the latter(P=0.0017). But there was no significant difference in the Kd between the two groups. 2) In the comparison of type 1 vs type 2, alcoholics by cloninger's classification $B_{max}$ of the latter was significantly higher than that of the farmer(P=0.0396). But there was no significant difference in the Kd between the two groups. 3) In the comparison of alcohol abuse vs alcohol dependence, there were no significant differences in the value of $B_{max}$ and Kd between the two groups. These results support the hypothesis of serotonin-deficit in alcoholism. Furthermore, it can be inferred that the increase of platelet serotonin receptors in alcoholics might be used as a trait marker.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.30 no.7 s.250
• /
• pp.671-681
• /
• 2006

This study focuses on the development of numerical procedure to analyze the nonlinear combustion instabilities in liquid rocket engine. Nonlinear behaviors of acoustic instabilities are characterized by the existence of limit cycle in linearly unstable engines and nonlinear or triggering instability in linearly stable engines. To discretize convective fluxes with high accuracy and robustness, approximated Riemann solver based on characteristics and Euler-characteristic boundary conditions are employed. The present procedure predicts well the transition processes from initial harmonic pressure disturbance to N-like steep-fronted shock wave in a resonant pipe. Longitudinal pressure oscillations within the SSME(Space Shuttle Main Engine) engine have been analyzed using the pressure-sensitive time lag model to account for unsteady combustion response. It is observed that the pressure oscillations reach a limit cycle which is independent of the characteristics of the initial disturbances and depends only on combustion parameters and operating conditions.

• Journal of Ship and Ocean Technology
• /
• v.4 no.2
• /
• pp.1-12
• /
• 2000

The present study concentrates on the weak-scatterer hypothesis for the nonlinear wave-body interaction problems. In this method, the free surface boundary conditions are linearized on the incoming wave profile and the exact body motion is applied. The considered problems are the diffraction problem near a circular cylinder and the ship response in oblique waves. The numerical method of solution is a Rankine panel method. The Rankine panel method of this study adopts the higher-order B spline basis function for the approximation of physical variables. A modified Euler scheme is applied for the time stepping, which has neutral stability. The computational result shows some nonlinear behaviors of disturbance waves and wave forces. Moreover, the ship response shows very close results to experimental data.

• Journal of Korean Academy of Nursing
• /
• v.6 no.2
• /
• pp.32-38
• /
• 1976

The advanced knowledge is increasing day by day due to the progress of medicine and tectonics, the increase of nursing research nowadays. In parallel with these, nursing profession has a need of the nursing care with improvement of new Knowledge, tectonics and nursing procedure through the insertive education. Therefore, this study was attempted to investigate that to grasp learning need of nurses about inservice educational play a pivotal role in the progress of inservice education. This study was made from 242 clinical nurse at 4 hospitals in Seoul and through question- are consisting of 1) ideological part 2) basic sciences 3) nursing part 4) administrative part 5) the others from 10 July '75 to 7 Oct. '75. The data were treated by percentage, Licker method, arid chi- square examination. Significant difference p is 0.05. The results of this studies are as follows : A. learning needs of nurses 1) Generally the learning needs of nurses is very high. 2) Of the learning need of inservice education for nurses, the highest learning need is as follow (Table 2 ) 1 st : Charting 2 nd : The ability of grasping patient's needs and problems. 3 rd ; The contents and the methods of the advanced nursing skill. 4 th ; The importance of team work 5 th ; The general knowledge of the various disease 6 th : The decision of a propriety nursing diagnosis under the general condition. 7 th ; The introduction of the new nursing theory. 8 th : The Nurses role and the responsibility in emergency and disaster. 9 th : The improvement of nursing skill for the perfect interpersonal relationship. l0th ; Cultural education: B . Verification of hypothesis 1. Hypothesis I , learning needs of nurses and educational level of nurse will be correlated, is rejected (Table 3 ) 2. Hypothesis II, learning need of nurses and duties of post will be correlated, is rejected (Table 4) 3. Hypothesis III, learning need of nurse and clinical experience of nurses will be correlated, is rejected (Table 5).

• 제어로봇시스템학회:학술대회논문집
• /
• 1997.10a
• /
• pp.124-127
• /
• 1997

In this paper, we propose a method of cooperative control based on immune system in distributed autonomous robotic system(DARS). Immune system is living body's self-protection and self-maintenance system. Thus these features can be applied to decision making of optimal swarm behavior in dynamically changing environment. For the purpose of applying immune system to DARS, a robot is regarded as a B lymphocyte(B cell), each environmental condition as an antigen, and a behavior strategy as an antibody respectively. The executing process of proposed method is as follows. When the environmental condition changes, a robot selects an appropriate behavior strategy. And its behavior strategy is simulated and suppressed by other robot using communication. Finally much simulated strategy is adopted as a swarm behavior strategy. This control scheme is based on clonal selection and idiotopic network hypothesis. And it is used for decision making of optimal swarm strategy.

• Journal of Korean Academy of Nursing
• /
• v.15 no.1
• /
• pp.30-43
• /
• 1985

Liver cirrhosis is the common cause of death in Korea today. But, if liver cirrhosis Patients were treated in the early stage of the disease Process, they can have a chance to carry their daily lives with prescribed medical and nursing regimens. Each patient has different health beliefs that there is a different Sick Role Behavior in the process of treatment. In order to increase and control the desired patient's Sick Role Behavior, it is important for nurses to understand the health beliefs influencing Sick Role Behavior. The purpose of this study was to determine factors influencing Sick Role Behavior and provide objective and scientific data to health education, treatment and nursing care. The subjects for this study were 80 Liver Cirrhosis patients selected from in and out patients of the medical department of four University Hospitals in Seoul, Won Joo and Mok Po city. Data was collected from Sep. 18, to Oct. 15, 1984. The measurement tool was the questionaire that developed by the investigator from the literature review based on Health Belief Model. The data Collection was done by interview. Analysis of data was done by use Mean, S.D., ANOVA, Pearson Correlation Coefficient and Stepwise Multiple Regression. The result of study were as follows: 1. The significant influencing variables on the Liver Cirrhosis Patient's Sick Role Behavior in general characteristics were Sex, Marital Status, Educational levels, Family's income and Duration after diagnosis. 2. Between the Sick Role Behavior and Health Belief Model, a) The first hypothesis that the stronger degree of Health Motivation, the higher degree of Liver Cirrhosis Patient's Sick Hole Behavior was supported (r=0.7892, p=0.0000). b) The second hypothesis that the higher degree of perceived susceptibility, the higher degree of Liver Cirrhosis Patients' Sick Role Behavior was supported (r=0.6383, p=0.0000) c) The third hypothesis that the higher degree of perceived severity, the higher degree of Liver Cirrhosis Patients' Sick Role Behavior was supported (r=0.5869, p=0.0000). d) The fourth hypothesis that the higher degree of perceived benefit, the higher degree of Liver Cirrhosis patient's Sick Role Behavior was supported (r=0.7535, p=0.0000). e) The fifth hypothesis that the lower degree of perceived barrier, the higher degree of Liver Cirrhosis Patient's Sick Role Behavior was supported(r=-9.7709, p=0.0000) f) The sixth hypothesis that the higher degree of knowledge in Disease, the higher degree of Liver Cirrhosis patients'lck Role Behavior was supported (r=0.7538, p=0.0000), g) In the correlation among variables, it was found positive correlation except that perceived barrier was negatively correlated. In the Stepwise Multiple Regression and Independent Variables, the factor“Health Motivation”could account for Sick Role Behavior in 62.28% of the Sample (F=128. 786, p<0.01). When the factor“perceived barrier”is added to this, it account for 70.38% of Sick Role Behavior (F=93.479, p <0.01) and the factor“knowledge in disease”is also included, it account for 74.78% of Sick Role Behavior (F=75.131, p <0.01). Finally, when the factor“perceived susceptibility”is included, it account for 75.03% of Sick Role Behavior (F=56.329, p <0.01).