• Journal of Hospice and Palliative Care
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• v.1 no.1
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• pp.65-68
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• 1998

The neuropathic pains are not well controlled by common analgesics and opioid drugs in terminal cancer patients. The types of these pains are divided within the two cages, one is due to continuous central sensitization and the other is due to paroxymal peripheral sensitization. The mechanism of continuous central sensitization is the activity of dorsal horn neurones that are activated by C-fiber input. The tricyclic antidepressants, non-tricyclic antidepressants, and oral local anaesthesia probably produce analgesic effects in neuropathic pains through suppression of this activity. The mechanism of paroxymal peripheral sensitization is the hyper-excitability of peripheral neurones. The neuropathic pains due to peripheral sensitization respond relatively the anticonvulsants and baclofen that stabilize membranes and suppress paroxymal electrical discharge. The patients was a 38-year-old female who complained of hyperthemia on upper right extremity. The symptom of this patient was improved with anticonvulsant(dilantin 600mg).

• The Journal of Korean Medicine
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• v.25 no.3
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• pp.203-211
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• 2004

Objectives : We report an unusual case of a 57-year old woman with spasticity following fever of unknown origin (the origin of her fever was not certain by western medical diagnosis). Malignant hyperthemia with spasticity couldn't be cured by general western medical therapy, and furthermore the function of liver and renal system was worsened as a consequence of drugs. Methods : We diagnosed the watery state of the patient as seupon (습온) with gyeonggwol (경궐) through pattern identification (변증) of symptoms and signs. Results : This patient who had spasticity with malignant hyperthermia was treated by optical management of herb medicine and acupuncture, and should need long-term observation. Conclusions : We want to show that trial by febrile diseases can solve fever and spasticity.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.2 s.33
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• pp.171-178
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• 2007

Objective : The aim of this study was to evaluate Yangdorak and D.I.T.I. for analysis of Symptom-complexes. Method : This study was selected 26 acne patients in Dongshin University Oriental Medical Hospital. We used Yangdorak (SME5800N, Sord Medicom Co., Korea) and D.I.T.I. (Digital Infrared Thermal Imaging 256, Dorex Inc, Orange CA, USA) and investigated the results of Yangdorak and D.I.T.I.. We made a comparison according to Deficiency or Excess(虛實) of acne patients. Result : In comparing Yangdorak results according to Deficiency or Excess(虛實) of acne patients, Triple-energizer(三焦), Intestine(大腸), Liver(肝), Stomach(胃) meridian in Excess group are higher than Deficiency group, and Kidney(腎) meridian in Deficiency group are lower than Excess group. D.I.T.I. reveald hyperthemia of face and chest on acne patients. The temperature of face and chest on Excess group is higher than Deficiency group. There is no statistically significant value compared with data of other group.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.5
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• pp.1135-1148
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• 2006

The effect of heat on the cancer have been keen since ancient orint medic. Quantitative biologic techniques were applied to the investigation of heat, and the resulting studies have defined a firm rationale for the expectation that hypertherima will be useful in the treatment of cancer. This promise led to activity in developing physical means to produce and measure hyperthermia in patients. Hyperthermic treatments for cancer are grouped into two categories according two the amount of tissue bing heated during the treatments. The categories commonly used are localized, regional, and whole body hyperthermia. Hyperthermia is a situation referring to yang-heat. In orient medic, It refers to vital-qi and the driving force of life activities. Our paper reviewed the present state of the the hyperthemia, outline some major impediments to progress at this time, and suggest researching approches in order to define the role of hyperthermia in the treatment of cancer.

• Journal of Biomedical Engineering Research
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• v.30 no.5
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• pp.418-427
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• 2009

As many people are westernizing their life style and food consumption habits, a number of patients who have malignant tumors which grow very rapidly and hazardously destroy the human body are increasing. Ultrasonic hyperthermia is not only one of the tumor treatment methods which employs the non-radioactive ultrasonic waves to increase the temperature at the tumor region up to $40\sim45^{\circ}C$ to destroy and suppress tumor cells but also has been proved by many studies. Due to the rapid development of High Intensity Focused Ultrasound(HIFU), the ultrasound hyperthemia extensively boosts its applications in clinical field. For those reasons, Computed simulation factor should be needed before inspection to patients. To prove efficiency of ultrasonic hyperthermia, precise acoustic field measurement considering tissue characteristics and a heating experiment with tissue mimicking material phantom were conducted for effectiveness of simulation program. Finally, in this study, the computer simulation program verified the anticipated temperature effects induced by ultrasound hyperthermia. In the near future, it is hoped that this simulation program could be utilized to improve the efficiency of ultrasound hyperthermia.

• The Korean Journal of Zoology
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• v.32 no.2
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• pp.134-141
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• 1989

The present investigation aims at elucidating a possible mechanism of heat inactivation of SCK ceils by comparing the kinetics of cell lethality and protein degradation in the presence of heat protector or heat sensitizer. The effect of heat sensitizer and protector was exhibited in both cell survival and protein degradation kinetics, the magnitude of the effect being much profound for the protector compared to the sensitizer. A conclusion to he drawn from the present experiment is that there is no direct correlation between cell lethality and protein degradation. Rather, protein degradation, which might occur in the membrane, causes cell inactivation indirectly, possibly by altering the cellular environment. Accordingly, further studies are needed to get insight into the mechanism of cell inactivation by hyperthermia.